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Erlin Yustin Tatontos
POLTEKKES KEMENKES MATARAM
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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THE EFFECT OF STARTING READING ON RESULTS SERUM GLUTAMIC PYRUVIC TRANSMINASE (SGPT) ON ENZYME TESTING Yulia Aida; Yunan Jiwintarum; Fihiruddin; Erlin Yustin Tatontos
Journal of Indonesia Laboratory Students (JILTS) Vol. 5 No. 2 (2026): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v5i2.525

Abstract

Background: Serum Glutamic Pyruvic Transaminase (SGPT), also known as alanine aminotransferase (ALT), is a clinical chemistry parameter that can be used to evaluate hepatocellular conditions based on enzyme activity. The kinetic method is performed by observing changes in absorbance during the enzymatic reaction. One analytical aspect related to the measurement of enzyme activity is the initial reading time (starting reading), as differences in measurement time may be associated with variations in the test results. Objective: This study aimed to determine whether variations in starting reading time affect SGPT test results. Research Methods: This study employed an experimental static group comparison design. The samples consisted of 6 respondents who were examined using variations in starting reading time after substrate addition, namely at the 1st to 5th minutes. The examination was performed using the IFCC kinetic method, and the results were expressed in U/L. The data were analyzed descriptively and followed by the Friedman test. Research Results: The mean SGPT activity at starting reading times of the 1st, 2nd, 3rd, 4th, and 5th minutes was 10.17 U/L, 9.33 U/L, 9.00 U/L, 9.67 U/L, and 8.17 U/L, respectively. The highest mean value was observed at the 1st minute, while the lowest mean value was found at the 5th minute. The Friedman test resulted in an Asymp. Sig. value of 0.608 (p>0.05), indicating that there was no statistically significant difference among the variations in starting reading time. Conclusion: Variations in starting reading time from 1 to 5 minutes did not show a significant effect on SGPT test results under the conditions of this study.
Comparison of Fast and Time Blood Glucose Levels in Chronic Disease Management Program Patients (Proalnic) and Non-Prolanic with Diabetes Mellitus in Praya Health Center Miftahul Aini; Erlin Yustin Tatontos; Nurul Inayati; Iswari Pauzi
THRIVE Health Science Journal Vol. 1 No. 1 (2024): March
Publisher : Balai Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56566/thrive.v1i1.92

Abstract

Glucose is the most important carbohydrate which is mostly absorbed into the bloodstream as glucose and other sugars are converted into glucose in the liver. Blood glucose levels are closely related to DM. Prolanic (Chronic Disease Management Program) is a health service system that involves participants from Health Facilities and BPJS health in the context of health care for participants suffering from chronic diseases including diabetes mellitus to achieve optimal quality of life with cost-effective and efficient health services. To determine the comparison of fasting and intermittent blood glucose levels in prolanic and non-prolanic patients suffering from DM at Praya Health Center. : This type of research is Analytical Observation, the sample is taken purposively. A sample of 30 respondents, in this study were 15 respondents who took prolanis and 15 respondents who did not follow prolanis who had a history of diabetes mellitus and underwent blood glucose level checks at the UPTD BLUD Laboratory of Praya Health Center. Based on research that has been done, the average fasting blood glucose level in prolanis is 158 mg/dl and fasting glucose is 204 mg/dl. Meanwhile, non-prolanic fasting glucose levels are 156 mg/dl and fasting glucose levels are 204 mg/dl.
Analysis of Circadian Rhytme Variations on Glucose Examination Results Putri Ziddanur Rahmani; Yunan Jiwintarum; Erlin Yustin Tatontos; Iswari Pauzi
THRIVE Health Science Journal Vol. 1 No. 2 (2024): September
Publisher : Balai Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56566/thrive.v1i2.234

Abstract

Background: Circadian rhythm is a term used to describe the 24-hour physiological rhythm of organisms. According to Minister of Health Regulation no. 43 of 2013 concerning How to Organize a Good Clinical Laboratory, the Circadian rhythm variation is explained in the body as levels of certain substances change from time to time. Changes in substance levels that are influenced by time can be cyclical, such as daily cycles (diurnal variations), monthly cycles (menstruation), or linear/straight lines, such as age. Classic experiments using a 72-hour glucose clamp methodology, demonstrated that humans exhibit a robust Circadian rhythm in insulin secretion, independent of food and glycemia. Additionally, a cell-autonomous Circadian clock appears to oversee the diurnal rhythm in glucose-induced insulin secretion.Research Objectives: Knowing the analysis of Circadian rhythm variations on glucose examination results. Research Methods: Analytical observational analysis using cross sectional methods and purposive sampling techniques. The sample population of applied TLM undergraduate students class of 2020 had blood serum taken and using the Slovin formula to determine the sample size, 36 samples were obtained with respondents without a history of diabetes mellitus. Data analysis used the Paired t-test statistical test. Research Result: The results obtained from the examination of the average glucose level at the time of sampling in the morning were 80.25 mg/dl, in the afternoon 96.5 mg/dl, and in the evening 85.91 mg/dl. The results of the paired t-test statistical analysis obtained Sig. (2-tailed) or p 0.010 means p < 0.05 there is a difference in the average glucose results at the time of sampling in the morning and afternoon and Sig. (2-tailed) or p 0.115 means p > 0.05 there is no difference in the average glucose test results at the time of sampling in the morning and evening. Conclusion:  Blood glucose levels taken in the morning have lower average levels than during the day and evening.
Co-Authors . Kholik Aden Turmuji Aeni Halawiya Agrijanti, Agrijanti Agus Ikhsan Jayadi Anggun Sari Mianti Anky Frasatya Aolani, Almira Zaida Ari Khusuma Aurira Thrisna Dwi Aprianti Ayu Rosita Dendi Arisandi Dera Suci Elmaria Dramawan, Awan Eliza, Ida Eliza, Ida Erna Kristinawati Ersandhi Reshnleksmana Ershandi Resnhaleksmana Ershandi Resnhaleksmana Fadila Rizki Ananda Feni Wahyuni Fihiruddin, Fihiruddin Gunarti Gunarti Gunarti Gunarti Gunarti, Gunarti Hana Fatinah I Gede Arya Santika Arya I Gusti Ayu Ambarawati Iswara Sesa I Nyoman Purna I Wayan Getas I Wayan Getas I Wayan Sali Ida Eliza IGAN Danuyanti Iswari Pauzi Iswari Pauzi Khairunnisa Kholik, Kholik Kristinawati, Erna Kurnia Anindita Kurnia Rizki Lalu Sri Gede Lalu Sri Gede Lina Sundayani Lu’lu’il Adawiyah Maruni wiwin Danuarti Maruni Wiwin Diarti Maruni Wiwin Diarti Maruni Wiwin Diarti Maruni Wiwin Diarti Maruni Wiwin Diarti Maruni Wiwin Diarti Maruni Wiwin Diarti Maswan, Moch Miftahul Aini Mutiara Rachmawati Suseno Nanda Yuniza Pratiwi Ni Nengah Yunita Nurul Inayati Nurul Inayati Nurul Inayati Nurul Inayati Nurul Inayati Nurul Inayati Nurul Inayati Putri Ziddanur Rahmani Putu Dita Septiani Putu Femila RAI WIADNYA, IDA BAGUS Riska Novitasari Rizki, Kurnia Rohmi Rohmi Rohmi, Rohmi Septiani, Erna Septiawan, Dandi Siti Malika Amini Siti zaetun sofiatummina Thomas Tandi Manu Titin Emilia Nirmala Sari Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip, Urip Wahyu Ardiansyah Yudha Anggit Jiwantoro Yulia Aida Yuliana Wardani Yunan Jiwintarum Yunan Jiwintarum Yunan Jiwintarum Yunan Jiwintarum Yunan Jiwintarum Yunkiy Allisa Septiana Putri Zainal Fikri