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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Journal of Agromedicine and Medical Sciences Mutiara Medika: Jurnal Kedokteran dan Kesehatan MNJ (Malang Neurology Journal) Majalah Kedokteran Sriwijaya JPSriwijaya Biomedical Journal of Indonesia Molecular and Cellular Biomedical Sciences (MCBS) Jurnal Surya Medika Jurnal Penelitian Pendidikan IPA (JPPIPA) Syntax Literate: Jurnal Ilmiah Indonesia Acta Biochimica Indonesiana Oceana Biomedicina Journal SRIWIJAYA JOURNAL OF MEDICINE Majalah Patologi Indonesia Medica Hospitalia Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Best Journal (Biology Education, Sains and Technology) Indonesian Journal of Global Health research Jurnal Pengabdian Masyarakat: Humanity and Medicine Bioscientia Medicina : Journal of Biomedicine and Translational Research Conferences of Medical Sciences Dies Natalis Eduvest - Journal of Universal Studies Jurnal Keperawatan Molekul: Jurnal Ilmiah Kimia Jurnal Kesehatan Indonesian Journal of Global Health Research
Zen Hafy
Universitas Sriwijaya
Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Pengembangan Bahan Alam Dari Siput Gonggong (Laevistrombus Sp.) Untuk Penyembuhan Luka: Tinjauan Histologis Fadilah, Rizka; Hafy, Zen; Larasati, Veny
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v10i10.62261

Abstract

Penyembuhan luka merupakan proses biologis kompleks yang melibatkan fase inflamasi, proliferasi, dan remodeling jaringan. Pemanfaatan bahan alami dari laut, seperti siput gonggong (Laevistrombus sp.), menawarkan potensi besar sebagai agen penyembuh luka karena kandungan senyawa bioaktifnya yang memiliki aktivitas antimikroba, antiinflamasi, dan antioksidan. Penelitian ini bertujuan untuk meninjau potensi ekstrak siput gonggong dalam mempercepat penyembuhan luka melalui analisis terhadap kandungan bioaktif, mekanisme kerja, dan bukti histologis. Kajian dilakukan secara sistematis terhadap literatur dari PubMed, ScienceDirect, Google Scholar, dan Scopus dalam lima tahun terakhir hingga April 2025, dengan fokus pada aktivitas biologis moluska laut dan aplikasinya pada regenerasi jaringan kulit. Hasil tinjauan menunjukkan bahwa siput gonggong mengandung protein histon H2A, peptida antimikroba (AMPs), flavonoid, alkaloid, dan saponin yang berperan dalam menekan sitokin proinflamasi (TNF-α, IL-6), meningkatkan sitokin antiinflamasi (IL-10), serta menstimulasi proliferasi fibroblas, angiogenesis, dan sintesis kolagen melalui jalur NF-κB, PPAR-γ, dan TGF-β/Smad. Secara histologis, senyawa ini mempercepat reepitelisasi dan meningkatkan deposisi kolagen pada jaringan luka. Dengan demikian, ekstrak siput gonggong memiliki potensi besar sebagai bahan dasar alami untuk pengembangan produk dermatologis dan farmasi yang aman, efektif, serta berkelanjutan.
The Relationship Between Quantitative C-Reactive Protein (CRP) and the Number of Leukocytes and Blood Edition Rate (ESR) in Optic Neuritis Patients Ramadhayanti, Lidya; Hafy, Zen; Sari, Nurmalia Purnama
Indonesian Journal of Global Health Research Vol 6 No 3 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i3.3164

Abstract

Optic neuritis (ON) is a demyelinating inflammatory process that causes sudden visual impairment that can occur in one or both eyes simultaneously or successively. Optic neuritis (ON) can be caused by demyelinating diseases of the central nervous system, immune system diseases, infectious diseases, and can also be caused by inflammatory responses and vaccinations. This study aimed to determine the relationship between quantitative c-reactive protein (CRP) and leukocyte count and blood edition rate (ESR) in patients with optic neuritis. The most common pathophysiology of optic neuritis is inflammatory optic neuropathy associated with multiple sclerosis. In optic neuritis, demyelination occurs due to inflammation of the optic nerve with a lesion pathology similar to plaque in the central nervous system of someone with multiple sclerosis. There will be perivascular swelling, edema of the myelinated nerve sheath, and myelin damage. Inflammation of the retinal vascular endothelium may precede demyelination. Myelin damage is more severe than the damage found in axons. This research was conducted to determine the correlation between quantitative CRP levels and leukocyte counts and erythrocyte sedimentation rate levels in optical neuritis patients. The type of research used is quantitative research with an analytical observational research design, namely a cross-sectional approach. CRP and ESR are two commonly performed laboratory tests that may help physicians in accurately diagnosing and following many complex disease conditions. The relationship between CRP levels and leukocyte counts is to evaluate the effectiveness of treatment response.
Vitamin D Levels in Epilepsy Patients at the Neurology Polyclinic, Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia Sri Handayani; Partan, Radiyati Umi; Zen Hafy; Fitri Octaviana; Citra Ananta Avis; Rini Nindela; Selly Marisdina
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 7 No. 12 (2023): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v7i12.949

Abstract

Background: In epilepsy patients, treatment is often lifelong and anti-epileptic drugs (AEDs) can be divided into two general groups, namely drugs that affect cytochrome P-450 (CYP-450) such as carbamazepine, phenytoin, primidone, or valproic acid, and those that affect minimal cytochrome P-450 such as gabapentin, vigabatrin, levetiracetam, oxcarbazepine, or topiramate. AEDs include various drugs that can cause a decrease in vitamin D levels. Therefore, this study was aimed at examining vitamin D levels in epilepsy patients who took AEDs at the neurology polyclinic at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia. Methods: This research is a descriptive study with a cross-sectional design using primary data obtained from the results of patient examinations using laboratory tests and secondary data from medical records. Results: As many as 78% (14 subjects) who received monotherapy had vitamin D levels below normal, and 16 subjects, or 76%, who received polytherapy had vitamin D levels below normal (p = 0.907). A total of 13 (72%) subjects who received phenytoin had vitamin D levels below normal, as well as 5 (63%) subjects who received carbamazepine and 12 (92%) subjects who received other therapies (p = 0.235). A total of 12 (67%) subjects who received therapy for 1-3 years and 18 (86%) subjects who received therapy > 3 years had vitamin D levels below normal (p = 0,406). Conclusion: Vitamin D deficiency is a crucial problem in epilepsy patients receiving AED therapy, where more than 75% of patients have vitamin D deficiency. In this study, vitamin D deficiency did not have a significant relationship with the type of therapy (monotherapy or polytherapy) or the type of drug used. used, duration of therapy, and frequency of sun exposure.
Procalcitonin Levels in Pulmonary Tuberculosis and Bacterial Pneumonia: A Cross-Sectional Study at a Tertiary Hospital in Indonesia Abdullah Fikri; Hadi Nugraha Mustofa; Zen Ahmad; Zen Hafy
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 4 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i4.1245

Abstract

Background: Pulmonary tuberculosis (TB) and bacterial pneumonia are respiratory infections with high morbidity and mortality rates. Despite having similar clinical symptoms and radiological findings, these conditions require different treatment approaches. Procalcitonin is a potential biomarker to differentiate these conditions, as its levels tend to increase in bacterial infections but not in TB. This study aims to compare procalcitonin levels in patients with pulmonary TB and bacterial pneumonia. Methods: This research employed an observational analytic design with a cross-sectional approach conducted at Dr. Mohammad Hoesin General Hospital (RSMH), Palembang. The study subjects were patients with pulmonary TB and bacterial pneumonia who met the inclusion and exclusion criteria. Procalcitonin levels were measured using ELISA methods. Data were analyzed to determine differences in procalcitonin levels between the two groups. Results: The study found that procalcitonin levels in bacterial pneumonia patients were significantly higher than those in pulmonary TB patients (p<0.05). These findings indicate that procalcitonin levels can serve as a diagnostic parameter to distinguish between the two conditions. Conclusion: Procalcitonin levels can be a useful biomarker for differentiating pulmonary TB from bacterial pneumonia. This biomarker is expected to assist clinicians in making more accurate diagnoses and expediting clinical decision-making.
Peran Polimorfisme Promotor Gen Interleukin-10 pada Penyakit Kusta: Tinjauan Sistematik Desi Oktariana; Irsan Saleh; Zen Hafy; Iche Andriyani Liberty
Majalah Kedokteran Indonesia Vol 73 No 1 (2023): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.73.1-2023-816

Abstract

Introduction: Leprosy remains a significant problem in Indonesia as the number of cases has not been eliminated until now. One of the cytokines that plays a role in the disease is interleukin-10 (IL-10), which has a dominant anti-inflammatory effect and influences the immunopathogenesis of leprosy. Genetic factors, including the IL-10 gene promoter polymorphism, affect the amount of IL-10 produced, thereby increasing the risk of leprosy. Therefore, the objective of this study is to gather information on the role of IL-10 gene promoter polymorphism in the development of leprosy.Method: A systematic review method was used to identify, evaluate, and extensively discuss published works through national and international journals such as Google Scholar, Science Direct, Elsevier, EBSCO, Medline, PubMed, Proquest, and Wiley. The study was conducted by searching relevant keywords related to the research topic in these databases. Subsequently, article selection was performed based on predetermined inclusion and exclusion criteria. The selected articles were then evaluated for quality to ensure accuracy and reliability of the presented information. Finally, the results of this systematic review were used to obtain accurate and up-todate information regarding the role of IL-10 gene promoter polymorphism in leprosy.Results: This systematic review analyzed a total of 14 articles and revealed that results varied among study populations. However, there is consistent evidence to suggest that the IL-10 gene promoter polymorphism is associated with leprosy, which was found in the majority of the study populations.Conclusion: IL-10 gene promoter polymorphism tends to be associated with leprosy.
Improvement IL -10 and Reactive Oxygen Species (ROS) in HIV patients : Narrative Review Franajayakk, Indra; Legiran; Salim, Eddy Mart; Hafy, Zen
Jurnal Kesehatan - STIKes Prima Nusantara Vol 16 No 1 (2025): Jurnal Kesehatan Volume 16 Nomor 1 Tahun 2025
Publisher : LPPM Universitas Prima Nusantara Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35730/jk.v16i1.1234

Abstract

Background: Infection Human Immunodeficiency Virus (HIV) is still become problem scary health​ for world community . This virus infection causes a bunch symptom disease characterized by with weakening system immunity body . A collection of symptoms This known with designation Acquired Immune Deficiency Syndrome (AIDS). Consequence the decline system immunity , HIV sufferers will prone to For caught various disease infections that can have fatal consequences. Objective: For know How improvement IL-10 and Reactive Oxygen Species (ROS) levels in HIV patients . Research methods: This use Narrative Review design . Articles searched from Google Scholar, PubMed, Science Direct, and EMBASE/ Elviser with use relevant keywords , then chosen based on criteria that have been set , and objectives study . Results: Increased levels of IL-10 and Reactive Oxygen Species (ROS) in patients results in a decrease in the immune system, this is characterized by increased virus replication, deactivation macrophages and depletion of the number of lymphocytes, so that the progression of the infection towards AIDS can occur. Conclusion: HIV infection causes the occurrence dysfunction mitochondria and enhancement production Reactive Oxygen Species (ROS) in cells CD4 + T lymphocytes. Various viral proteins, such as the envelope proteins Gp120, Tat, Nef and Vpr , are able to increase ROS production through various different pathways. The increase in ROS that occurs can increase mRNA expression through activation Nuclear Factor Kappa B ( NFκB ), increased IL-10 mRNA expression ultimately will increase IL-10 levels
PERAN IMUNOMODULATOR VITAMIN D TERHADAP INTERLEUKIN 6 PADA PENDERITA DIABETES MELITUS TIPE 2 Wulandari, Septi; Hafy, Zen; Liana, Phey
BEST Journal (Biology Education, Sains and Technology) Vol 8, No 1 (2025): Juni 2025
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v8i1.11119

Abstract

Diabetes Melitus Tipe 2 (DMT2) adalah penyakit metabolik kompleks dengan peradangan kronis sebagai salah satu mekanisme penting dari patogenesisnya. Interleukin-6 (IL-6) memiliki peran signifikan dalam memperburuk resistensi insulin dan meningkatkan risiko komplikasi vaskular pada penderita DMT2. Vitamin D diketahui tidak hanya berfungsi dalam metabolisme tulang tetapi juga bertindak sebagai imunomodulator yang mampu memodulasi respons inflamasi. Tinjauan literatur ini bertujuan untuk menganalisis peran vitamin D dalam mengatur tingkat IL-6 pada pasien DMT2 berdasarkan studi yang dipublikasikan sebelumnya. Literature review ini bertujuan untuk menjelaskan pengaruh vitamin D dalam menurunkan sitokin proinflamasi IL-6 pada pasien diabetes mellitus tipe 2. Metode yang digunakan dalam artikel ini adalah penelusuran artikel melalui database Pubmed, Springer Link dan Google Scholar. Tahun penerbitan sumber pustaka adalah dari tahun 2011 hingga 2025 dengan 27 sumber pustaka. Hasil: Beberapa literatur menunjukkan bahwa kadar vitamin D serum yang cukup atau pemberian suplemen vitamin D memiliki kemampuan untuk mengurangi IL-6 dan berkontribusi terhadap perbaikan kontrol glikemik Hasil yang diperoleh antar studi belum sepenuhnya konsisten karena adanya perbedaan metodologi, dosis suplementasi, durasi intervensi, serta karakteristik subjek penelitian. Beberapa literatur menunjukkan bahwa kadar vitamin D serum yang cukup atau pemberian suplemen vitamin D memiliki kemampuan untuk mengurangi IL-6 dan berkontribusi terhadap perbaikan kontrol glikemik
Rhodomyrtus tomentosa Leaf Extract Cream Suppresses MMP-1 Expression and Epidermal Thickening in UVB-Irradiated Swiss Webster Mice Defa Agripratama Ali; Zen Hafy; Veny Larasati; Nora Ramkita
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 10 No. 6 (2026): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v10i6.1609

Abstract

Background: Ultraviolet B (UVB) radiation induces matrix metalloproteinase-1 (MMP-1) expression and epidermal hyperplasia, contributing to photoaging. Rhodomyrtus tomentosa (karamunting) is rich in polyphenolic compounds with documented antioxidant properties, but its in vivo photoprotective effects remain unexplored. Methods: We investigated the effects of R. tomentosa leaf extract cream at varying concentrations (0%, 12.5%, 25%, 50%) on UVB-irradiated Swiss Webster mice (n=4 per group). UVB exposure was standardized at approximately 150 mJ/cm² per session over seven consecutive days. Vitamin E cream served as a positive control. Immunohistochemical staining quantified MMP-1 expression as a percentage of positive cells, while hematoxylin-eosin histology measured epidermal thickness. Results: Kruskal-Wallis testing revealed significant differences in both MMP-1 expression (H=10.43, p=0.015) and epidermal thickness (H=10.88, p=0.012). The 25% extract concentration optimally suppressed MMP-1 expression (mean 45.94% of positive cells) compared to the untreated UVB control (89.53%). A biphasic dose-response pattern emerged, with hormetic effects observed at 50% concentration (76.45%), suggesting polyphenol pro-oxidant activity at excessive concentrations. Epidermal thickness normalized with 25% treatment (71.8 μm) versus UVB control (93.4 μm). Immunohistochemical intensity decreased progressively with treatment intensification through 25%, supporting suppression of MMP-1-mediated collagen degradation. Conclusion: R. tomentosa leaf extract cream at 25% concentration effectively suppresses MMP-1 expression and normalizes UVB-induced epidermal thickening in mice. The hormetic response at higher concentrations highlights the importance of dose optimization in phytotherapeutic development. This work establishes the first in vivo evidence for karamunting leaf extract as a photoprotective agent and supports further clinical translation.
Ekspresi Penanda Tumor CEA dan Calretinin pada Adenocarci-noma dan Sel Mesotel Reaktif dari Cairan Pleura . Aspitriani, Mezfi Unita, Zulkarnain Musa, Zen Hafy
Majalah Patologi Indonesia Vol. 20 No. 3, September 2011
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

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Abstract

ABSTRAK Latar belakang Perbedaan gambaran morfologi antara sel mesotel reaktif dan adenokarsinoma pada efusi pleura masih merupakan salah satu tantangan dalam diagnostik sitologi. Sejauh ini, telah banyak penanda tumor yang digunakan pada efusi pleura dengan berbagai derajat efektivitas. Penelitian ini bertujuan untuk mengetahui tingkat positifitas carcinoembryonic antigen (CEA) dan calretinin pada adenokarsinoma dan sel mesotel reaktif dari sitologi cairan pleura. Bahan dan cara Tujuh puluh empat sampel arsip slaid dari efusi pleura dengan diagnosa adenokarsinoma atau sel mesotel reaktif diperoleh selama periode waktu 1 Februari 2010-31 Januari 2011. Semua slaid berasal dari spesimen sitospin dengan pulasan Papanicolaou dan Diff Quik kemudian dipulas ulang dengan menggunakan antibodi CEA dan calretinin. Ekspresi kedua penanda tumor ini dievaluasi untuk menilai tingkat positifitas, korelasi antara kedua antibodi dianalisis dengan uji korelasi non parametrik Kendall’s. Hasil Pulasan positif untuk CEA dan calretinin masing-masing sebesar 81,6% (31/38) dan 39,5% (15/38) pada kasus adenokarsinoma Untuk sel mesotel reaktif, positifitas CEA dan calretinin masing-masing sebesar 36,1% (13/36) and 88,9% (32/36). Koekspresi positif kedua penanda tumor dijumpai sebanyak 25% (9/36) pada kasus sel mesotel reaktif. Didapatkan korelasi negatif yang bermakna antara CEA dan calretinin dengan kekuatan korelasi sedang pada adenokarsinoma (p
Karakteristik Umur dan Histopatologi pada Subtipe Karsinoma Payudara Tripel Negatif . Suly Auline Rusminan, Heni Maulani, Fifie Julianita, Zen Hafy
Majalah Patologi Indonesia Vol. 21 No. 3, September 2012
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

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Abstract

ABSTRAK Latar belakang Karsinoma payudara tripel negatif (KPTN) adalah karsinoma payudara yang tidak mengekspresikan reseptor esterogen, progesteron dan HER-2. Proporsi kejadian KPTN adalah 10-17% dari seluruh karsinoma payudara. KPTN memiliki perjalanan klinis agresif, prognosis yang buruk dan karakteristik klinikohistopatologi serta molekular yang unik. Penelitian ini dirancang untuk mengetahui hal-hal yang terkait dengan karakteristik dan faktor-faktor yang diduga berhubungan dengan subtipe KPTN basal-like dan nonbasal-like berdasarkan tripanel petanda (CK14, EGFR dan 34βE12). Bahan dan cara kerja Penelitian observasi analitik ini menggunakan sampel 39 kasus KPTN dari Laboratorium Patologi Anatomik RSUP dr. Mohammad Hoesin Palembang (periode Juli 2009-Juli 2011). Pulasan imunohistokimia CK14, EGFR dan 34βE12 dilakukan untuk membedakan subtipe KPTN basal-like atau nonbasal-like, kemudian dianalisis hubungan antara karakteristik umur dan histopatologinya. Hasil KasusKPTN terbanyak didapatkan pada kelompok umur 45-49 tahun (33,3%), dengan rerata usia 55 tahun, umumnya adalah jenis karsinoma duktal invasif derajat keganasan tinggi (79,5%). Proporsi KPTN subtipe basal-like dijumpai pada 41% KPTN. Pada penelitian ini tidak dijumpai adanya hubungan statistik bermakna (p>0,05) antara umur dan karakteristik histopatologi yang meliputi ukuran tumor, pleomorfisme inti, jumlah kelenjar, jumlah mitosis, derajat keganasan, subtipe histologi, komponen DCIS, invasi limfovaskular, status limfonodus, tepi tumor dan area nekrosis dengan subtipe KPTN. Kesimpulan Berdasarkantripanel petanda imunohistokimia (CK14, EGFR dan 34βE12) didapatkan 41% kasus termasuk KPTN tipe basal-like. Tidak ada hubungan bermakna antara karakteristik umur dan histopatologi dengan subtipe karsinoma payudara tripel negatif. Kata kunci : Karsinoma payudara tripel negatif, basal-like, CK14, EGFR, 34βE12, umur, karakteristik histopatologi. ABSTRACT Background Triple negative breast cancer (TNBC) is defined as a subtype of breast cancer which is negative for estrogen receptor, progesterone receptor and HER-2. Accounts for 10-70% of all breast cancer.TNBC have aggressive behavior, poor prognosis, unique clinicohistopathologic characteristic and molecular profiles. This study designed to identified characteristics and related with TNBC subtype using tripanels CK14, EGFR and 34βE12. Methods This study was an analytical observasional study based on thirty nine cases of TNBC at the Anatomic Pathology Laboratory of Dr.Mohammad Hoesin General Hospital, Palembang since July 2009-July 2011 period, immunohistchemical staining for CK14, EGFR and 34βE12 were use to distinguish the TNBC basal-like and nonbasal-like subtype, and correlated with age and histopathologic characteristics. Results Most ofTNBC patients were 45-49 years old (33.3%), with mean 55 years old. Most of TNBC (79,5%) were high grade invasive ductal carcinoma (79,5%). Proportion of the basal-like TNBC subtype was 41%. No statistical correlation (p>0,05%) between age, and histopathologic characteristics including tumor size, nuclear pleomorphism, mitotic score, tubule formation score, histologic grade, DCIS component, lymphovascular invasion, lymph node status, margin, and necrosis area with TNBC subtype. Conclusion Based on thetripanel immunohistochemical marker (CK14, EGFR and 34βE12 determine 41% of cases as TNBC basal-like. No statistical correlation between age and histopathological characteristics with TNBC subtype. Key words: Triple negative breast cancer, basal-like, CK14, EGFR and 34βE12, age, histopathologic characteristic.
Co-Authors A, Rafdi A, Rafdi Abdullah Fikri Abdullah Sahab Afriyana Siregar Afriyana Siregar Agnes Felicia Lubis Agnes Felicia Lubis Agustian Dwi Putra Agustian Dwi Putra Agustina Br Haloho Amalia Amalia Anisah Nida'ul Haq Argentina, Fiva Ariesti Karmila aryani, Inda astri Aulia Annisa Rizki Bastian Bastian Bayu Winata Putera Calvin Ienawi Chairil Anwar Chairil Anwar Citra Ananta Avis Citra Dewi Defa Agripratama Ali Desi Arlindia Desi Oktariana Dian Puspitasari Didit Pramudhito Dwi Handayani Dwi Handayani Dwiana Ocviyanti Dwirini Retno Gunarti Dya Anggraeni Eddy Mart Salim Eddy Mart Salim Eddy Mart Salim Eddy Mart Salim Eddy Mart Salim Eddy Mart Salim, Eddy Mart Efrieni Erial Bahar Erial Bahar Erial Bahar Erial Bahar, Erial Ernawati Sinaga Evi Lusiana Fachmi Idris Fadhyl Zuhry Lubis Fadilah, Rizka Ferry Yusrizal Ferry Yusrizal Fitri Octaviana Fitri Octaviana Franajayakk, Indra Francisca Srioetami Tanoerahardjo Fransisca Srioetami Tanoerahardjo Fransisca Srioetami Tanoerahardjo Gita Dwi Prasasty Hadi Nugraha Mustofa Haekal M Handayani, Sri Hartati Harun Hudari Harun Hudari Harun, Yusril Heni Maulani Heni Pujiastuti Henny Sulastri Hermansyah Hermansyah Iche Andriyani Liberty Iche Andriyani Liberty, Iche Andriyani Indra Franajayakk Inggarsih, Rara Irawan Mangunatmadja Irsan Saleh Irsan Saleh Jusak Nugraha Jusuf Fantoni Kemas Ya'kub Rahadiyanto Kemas Ya'kub Rahadiyanto Kemas Ya’kub Rahadiyanto Kemas Yusuf Effendi Kms Yusuf Effendi Kms. Yusuf Effendi Kms. Yusuf Effendi Kms. Yusuf Effendi Kms. Yusuf Effendi Kodrati, Adika Krisna Murti Krisna Murti kurniati, nova Laida Neti Mulyani Legiran Legiran Legiran Legiran M, Haekal M, Haekal M. Irsan Saleh Masagus Irsan Saleh Hasani Maya Eka Apriyanti Meiliza Indriani Mgs. Irsan Saleh Mgs. Irsan Saleh Mohamad Sadikin Muhammad Irsan Saleh Nita Hertati Nora Ramkita Nova Kurniati Nova Kurniati Nova Kurniati Nova Kurniati Nova Kurniati Nova Lestari Novizar S Nur Riviati Ocktariyana, Ocktariyana Owen Hu Pancarani, Muftia Phey Liana Prihantika S., Sabrina Purnamasari, Septi Puspita, Riana Sari Puspita, Riana Sari R, Sentani R, Sentani Raden Muhammad Indra Radiyati Umi Partan Radiyati Umi Partan, Radiyati Umi Rafdi A Rafika Novianti Rahadiyanto, Kemas Ya'Kub Rahmi Widiyawati Ramadhayanti, Lidya Ramzi Amin, Ramzi Rasyid, Riana Sari Puspita Ray Suga Aulia Ray Suga Aulia Sentani Riana Sari Puspita Riana Sari Puspita Rasyid Rikka Wijaya Rini Nindela Rini Nindela, Rini Rizal Sanif Rizka Fadilah Rouly Pola Pasaribu S, Novizar S, Novizar Sabri Prihantika Sabrina Prihantika Saleh, M Irsan Saleh, Mgs. M. Irsan Sari, Nurmalia Purnama selly marisdina Selvy Apriani Sentani R SEPTI WULANDARI Soilia Fertilita Sri Handayani Sri Sulpha Siregar Sri Sulpha Siregar Subandrate Sudarto Sudarto Suly Auline Rusminan Susiwati Susiwati Syifa Alkaf Tanoerahardjo, Francisca Srioetami Tungki Pratama Umar Venny Larasati Venny Larasati Veny Larasati Veny Larasati Verli Saniba Welly Salutondok Wresnindyatsih Ya’kub Rahadiyanto Yudianita Kesuma, Yudianita Yulia Iriani Yunni Diansari Yusuf Effendi Yusuf Effendi Yusuf Effendi Yusuf Effendi Zen Ahmad Zen Ahmad Zen Ahmad Ziske Maritska Zulkarnain Musa