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All Journal Biospecies Jurnal Lahan Suboptimal Biosfer: Jurnal Tadris Biologi Biogenesis: Jurnal Ilmiah Biologi Proceeding International Conference on Global Resource Conservation AGRIVITA, Journal of Agricultural Science Indonesian Journal of Biotechnology Biota Biology, Medicine, & Natural Product Chemistry Journal of Tropical Biodiversity and Biotechnology Proceeding of the Electrical Engineering Computer Science and Informatics Science and Technology Indonesia Jurnal Penelitian Sains DIDAKTIKA BIOLOGI: Jurnal Penelitian Pendidikan Biologi Jurnal Biologi Tropis IJEMS (Indonesian Journal of Environmental Management and Sustainability) Jurnal Biolokus: Jurnal Penelitian Pendidikan Biologi dan Biologi Riau Journal of Empowerment Seminar Nasional Lahan Suboptimal Jurnal Gema Ngabdi Jurnal Vokasi Journal of Environmental Science and Sustainable Development Berkala Penelitian Hayati Jurnal Altifani Penelitian dan Pengabdian kepada Masyarakat Indonesian Journal of Applied Environmental Studies SRIWIJAYA JOURNAL OF ENVIRONMENT BIOVALENTIA: Biological Research Journal Jurnal Pepadu JURNAL BIOLOGI PAPUA Dikdimas : Jurnal Pengabdian Kepada Masyarakat Bulletin of Chemical Reaction Engineering & Catalysis Aksi Kita: Jurnal Pengabdian Kepada Masyarakat Edumaspul: Jurnal Pendidikan
Laila Hanum
Biology Department, Faculty Of Mathematics And Natural Sciences, Sriwijaya University, Indralaya, 30662, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Effect of Media and Plant Growth Regulator on Proliferation of Somatic Embryogenic Callus of Oil Palm (Elaeis gueenesis Jacq.) Sulaksono, Gogoh; Hasmeda, Mery; Hanum, Laila; Wendra, Fahmi; Santika, Baitha
AGRIVITA Journal of Agricultural Science Vol 46, No 2 (2024)
Publisher : Faculty of Agriculture University of Brawijaya in collaboration with PERAGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17503/agrivita.v46i2.4234

Abstract

The Pisifera type oil palm is an important palm variety and mostly used as a pollen source to produce Tenera commercial hybrid varieties. This research on proliferating fertile Pisifera oil palm callus using somatic embryogenesis method was conducted at the Tissue Culture Laboratory of PT. Sampoerna Agro, Tbk from February to August 2021 to find out the optimum basal media and the concentration of growth regulators on callus proliferation. The planting material was the primary callus from the previous research. This study used a factorial Completely Randomized Design with two factors. The first factor involved two types of basal media: MS and Y3, and the second factor consisted of different concentrations of growth regulators (PGR). All treatments were repeated three times. The results showed that the use of MS media supplemented with 6 mg/l NAA and 0.5 mg/l 2,4-D was the most effective treatment for the proliferation of embryogenic callus in term of callus initiation time, the capacity of primary callus formation, primary calli morphology and proliferation, and callus fresh weight.
Genetic Diversity and Phylogenetic Relationships of Pometia pinnata Variants from South Sumatra Using RAPD Markers Hanum, Laila; Novira, Sandra; Oktariansyah, Yadi
Jurnal Biologi Tropis Vol. 25 No. 4b (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4b.10536

Abstract

Matoa (Pometia pinnata J.R. & G. Forst) is a tropical tree of the Sapindaceae family widely distributed in Southeast Asia, yet the genetic diversity and evolutionary relationships among its variants in South Sumatra remain poorly understood. This study aimed to clarify the genetic structure of four local variants forest, red, yellow, and green matoa using Random Amplified Polymorphic DNA (RAPD) markers. Leaf samples representing each variant were collected across different regions of South Sumatra and analyzed through standard molecular procedures, including DNA extraction and RAPD amplification using five primers. Cluster analysis based on Jaccard’s coefficient and UPGMA revealed two major genetic groups, indicating substantial variation among the studied variants. Red and yellow matoa showed the closest genetic affinity, whereas forest matoa was the most distinct from the others. These findings demonstrate considerable intraspecific diversity within matoa populations in South Sumatra. The study provides essential baseline information that strengthens conservation strategies, supports potential breeding programs, and enhances understanding of the species’ evolutionary patterns within tropical ecosystems.
Secondary Metabolite Profile of Essential Oils of Kaffir Lime, Kalamansi, and Lime Fruit Peels from South Sumatra Astri Indah Lestari; Salni Salni; Laila Hanum
Edumaspul: Jurnal Pendidikan Vol 8 No 1 (2024): Edumaspul: Jurnal Pendidikan
Publisher : Universitas Muhammadiyah Enrekang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33487/edumaspul.v8i1.7753

Abstract

This study aims to determine the secondary metabolite content of the essential oils of kaffir lime, kalamansi and lime peels from South Sumatra. This research consisted of several stages, namely the stage of identifying kaffir lime, calamansi and lime plants, the stage of preparing tools and materials, the stage of distillation of the essential oils of kaffir lime, calamansi and lime peels and the stage of identifying the chemical components of essential oils using the GC-MS method. Based on research, it can be concluded that the main essential oil content of kaffir lime peel, calamansi and lime from South Sumatra are citronellal (24.55%), limonene (97.12%) and limonene (35.24%) respectively.
Exploration of Plastic Degrading Bacteria in the Musi River, PalembangCity Widjajanti, Hary; Annisa Kemala Tasya; Laila Hanum
Biota Vol 11 No 2 (2025): Jurna Biota 2025
Publisher : Faculty of Science and Technology Universitas Islam Negeri Raden Fatah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19109/biota.v11i2.27347

Abstract

Musi River is a waterway in South Sumatra that faces increasing plastic pollution, threatening aquatic ecosystems and human life. This study aims to identify and evaluate plastic-degrading bacteria from Musi River using phenotypic and molecular approaches. The methods of this study include bacterial isolation, plastic degradation test, and Scanning Electron Microscopy (SEM) analysis were carried out to assess degradation efficiency and changes in surface morphology, phenotypic and molecular identification. The results showed that isolates S1I3, S1I5, and S2I1 had high plastic degradation potential, with levels of 38.03%, 34.73%, and 30.46%, respectively. SEM observations showed changes in surface morphology, including pores and cracks. Molecular identification confirmed that S1I3 was Bacillus proteolyticus (99.87%), while S1I5 and S2I1 matched Bacillus cereus (100%).
Secondary metabolites from Lansium domesticum as potential anti-inflammatory iNOS inhibitors: An in silico study Yadi Oktariansyah; Laila Hanum; Muhammad Habiburrahman
Jurnal Biolokus : Jurnal Penelitian Pendidikan Biologi dan Biologi Vol 8, No 2 (2025): December
Publisher : Universitas Islam Negeri Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30821/biolokus.v8i2.4731

Abstract

Inflammation is a crucial mechanism by which the immune system combats disease. However, when it becomes uncontrolled, it can result in acute inflammatory disorders. Although non-steroidal anti-inflammatory drugs (NSAIDs) are widely used for treatment, their associated side effects have prompted the search for safer, natural alternatives. One of the enzymes central to the progression of acute inflammation is inducible nitric oxide synthase (iNOS), particularly its active site, plays a key role in the progression of acute inflammation. Lansium domesticum Corrêa, 1807 have been reported to contain secondary metabolites with anti-inflammatory potential, but their interaction with iNOS has not been systematically explored. This study is the first to comprehensively evaluate these secondary metabolites against iNOS using an in silico approach combing biological activity prediction, physicochemical and pharmacokinetic profiling, and molecular docking simulations. From 53 screened metabolites, nine compounds met drug-likeness and pharmacokinetic criteria and were further analyzed through molecular docking.  Ellagic Acid, (+)-Spathulenol, α-Cadinene, and τ-Muurolol showed substantial binding affinities at the iNOS active site, which suggests that they could be good anti-inflammatory agents. These results establish a basis for subsequent in vitro and in vivo validation aimed at creating safe, natural iNOS inhibitors as herbal-based for the alternative anti-inflammatory medicines.
Analisis Polimorfisme Padi Varietas Lokal Sumatera Selatan Berdasarkan Pendekatan PCR-RAPD Fikri Adriansyah; Laila Hanum; Muharni Muharni; Yuanita Windusari
Jurnal Lahan Suboptimal : Journal of Suboptimal Lands Vol. 7 No. 1 (2018): JLSO
Publisher : Research Center for Suboptimal Lands (PUR-PLSO), Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33230/JLSO.7.1.2018.347

Abstract

Adriansyah et al, 2018. Polymorphism Analysis of Local Varieties of South Sumatra Rice Based on PCR-RAPD. JLSO 7(1):50-58.The existence of rice germplasm is threatened because of the introduction of various high-yielding varieties. This study aimed to analyze rice kinship and conservation of local varieties of South Sumatra rice. This study was conducted in August 2015 to December 2015. DNA isolation using the Promega Wizard Purification Systems KIT. This study uses OPA-9 primer, OPA-10, OPA-13, OPA-16. All primers can amplify DNA with optimal quality. OPA-9 primers produced 5 DNA bands, OPA-10 primers produced 9 DNA bands, OPA-13 primers produced 12 DNA and Primary OPA-16 bands producing 9 ppita DNA.
Pengelolaan Penanaman Bayam Brazil Pada Tanah Tandus Secara Matematika dengan Menggunakan Eco-Enzyme Fitri Maya Puspita; Venty; Tri Handayani; Reza Andeka; Fidella Oktariana; Destia Maharani; Dewi Lisandra; Ayu Nursafitri; Laila Hanum; Evi Yuliza; Sisca Octarina; Yolanda Fitria
Aksi Kita: Jurnal Pengabdian kepada Masyarakat Vol. 1 No. 4 (2025): JULI-AGUSTUS
Publisher : Indo Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63822/xmh3gt88

Abstract

Penanaman Bayam Brazil (Alternanthera sissoo) di lahan kritis seperti tanah tandus dan rawan banjir memerlukan pendekatan pengelolaan yang inovatif. Penelitian ini membahas strategi pengelolaan berbasis eco-enzyme yang dikombinasikan dengan pemodelan matematika untuk mengoptimalkan pertumbuhan dan hasil tanaman. Eco-enzyme hasil fermentasi limbah organik, terbukti meningkatkan kesuburan dan retensi air tanah. Dalam praktiknya, pengelolaan dilakukan melalui persiapan tanah, aplikasi dosis eco-enzyme yang terukur, serta evaluasi pertumbuhan tanaman secara berkala. Evaluasi menunjukkan peningkatan pertumbuhan dan hasil tanaman secara signifikan. Penelitian ini menunjukkan bahwa pengelolaan berkelanjutan berbasis matematika dan teknologi bio-organik seperti eco-enzyme dapat menjadi solusi adaptif terhadap perubahan iklim dan degradasi lahan.
Analisis In Silico Metabolit Sekunder Lansium domesticum sebagai Agen Antimalaria Potensial yang Menargetkan Enzim Laktat Dehidrogenase (PfLDH) pada Plasmodium falciparum Hanum, Laila; Nirwana, Rahma Julia; Oktariansyah, Yadi; Harvianti, Yuniar
Biogenesis: Jurnal Ilmiah Biologi Vol 14 No 1 (2026)
Publisher : Department of Biology, Faculty of Sci and Tech, Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/bio.v14i1.62225

Abstract

Malaria continues to be a significant global infectious illness, with Plasmodium falciparum primarily responsible for the most severe and lethal cases, including cerebral malaria. P. falciparum lactate dehydrogenase (PfLDH), an essential enzyme in the parasite's glycolytic cycle, is a viable molecular target for the development of antimalarial drugs. The deficiencies in existing therapeutics underscore the necessity for novel candidate alternative drugs. Lansium domesticum, a native Indonesian plant, possesses bioactive compounds with potential antimalarial effects. This work sought to assess L. domesticum secondary metabolites as potential antimalarial agents using an in silico methodology. A total of 47 compounds were evaluated to forecast antimalarial efficacy, thereafter, assessing their physicochemical attributes, pharmacokinetic features, and toxicity profiles. Molecular docking was used to examine the interactions between potential drugs and the PfLDH target enzyme. Four compounds—is-3-Hexen-1-ol, Aromadendrene, Isoledene, and Hexadecanoic acid—fulfilled the necessary physicochemical, pharmacokinetic, and toxicological standards. Hexadecanoic acid demonstrated the most robust interaction with PfLDH, establishing three critical amino acid connections at the active site (GLY29, THR97, and HIS195) and exhibiting a superior binding affinity compared to control and natural ligands. The data indicate that hexadecanoic acid is a promising antimalarial candidate sourced from L. domesticum. Additional molecular dynamics simulations, together with in vitro and in vivo investigations, are required to validate its therapeutic efficacy.
DIVERSIFIKASI MAKANAN DAN MINUMAN BERBAHAN DASAR KULIT BUAH NAGA MERAH (Hylocereus polyrhizus) DI DESA PULAU SEMAMBU Hary Widjajanti; Indra Yustian; Laila Hanum; Elisa Nurnawati; Endri Junaidi; Nita Aminasih
Jurnal Pepadu Vol 7 No 1 (2026): Jurnal Pepadu
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/pepadu.v7i1.9355

Abstract

Kulit buah naga merah (Hylocereus polyrhizus) masih belum banyak dimanfaatkan oleh masyarakat, padahal pada kulit buah naga merah masih mengandung senyawa antioksidan dan senyawa lain yang sangat bermanfaat bagi manusia. Senyawa antioksidan mampu melawan oksidasi dalam tubuh. Kulit buah naga merah dapat diolah menjadi berbagai maacam makanan dan minuman yang bermanfaat bagi kesehatan manusia. Kegiatan ini bertujuan untuk meningkatkan pengetahuan masyarakat Desa Pulau Semambu khususnya ibu-ibu dan remaja putri dalam diversifikasi (penganekaragaman) makanan dan minuman berbahan dasar kulit buah naga merah (Hylocereus polyrhizus) untuk meningkatkan ekonomi masyarakat. Kegiatan pengabdian kepada masyarakat yang dilakukan di desa Pulau Semambu kecamatan Indralaya Utara Kabupaten Ogan Ilir Provinsi Sumatera Selatan meliputi demonstrasi, pelatihan, pendampingan dan evaluasi. Kegiatan evaluasi dirancang dengan membagikan kuesioner kepada khalayak sasaran. Demonstrasi dan pelatihan pembuatan beraneka ragam makanan dan minuman berbahan dasar kulit buah naga telah dilaksanakan dan dapat diterima dengan baik oleh khalayak sasaran yang terdiri atas ibu-ibu remaja putri. Kegiatan penyuluhan Diversifikasi makanan dan minuman berbahan dasar kulit buah naga merah telah memberikan pengetahuan dan ketrampilan baru bagi masyarakat  desa Pulau Semambu yang diharapkan dapat memberikan alternatif usaha untuk meningkatkan pendapatan keluarga.  Masyarakat Desa Pulau Semambu kecamatan Indralaya Utara memberikan respon positif  dan partisipasi aktif dalam pelaksanaan kegiatan pengabdian kepada masyarakat. Hasil evaluasi menunjukkan sebanyak 92,4 – 96,3 % khalayak sasaran sangat puas terhadap metode dan cara penyampaian materi penyuluhan, 96,3%  menyatakan bahwa kegiatan yang dulaksanakan sangat bermanfaat, 88,9%  menyatakan bahwa kegiatan sangat bisa dilanjutkan.
Phytochemical Profiling and Cytotoxic Evaluation of Marasi (Curculigo latifolia) Leaf Extract and Fractions Against MCF-7 Breast Cancer Cells Nanda Lia Putri Sari; Salni Salni; Elfita Elfita; Laila Hanum; Elisa Nurnawati
Biology, Medicine, & Natural Product Chemistry Vol 15, No 1 (2026)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2026.151.1725-1735

Abstract

Breast cancer has the highest incidence among women in Indonesia. The exploration of natural products as sources of selective anticancer agents with minimal side effects continues to attract considerable attention. Marasi (Curculigo latifolia) is reported to contain secondary metabolites with potential antiproliferative properties. This study aimed to perform phytochemical profiling using thin-layer chromatography (TLC) and liquid chromatography–mass spectrometry (LC–MS), as well as to evaluate the cytotoxic activity of C. latifolia leaf extracts and fractions against MCF-7 breast cancer cells. TLC analysis indicated that the leaf extract of C. latifolia and its fractions comprise diverse secondary metabolites, such as phenolics, terpenoids, flavonoids, and tannins. Meanwhile, LC–MS profiling demonstrated that nitrogen-bearing heterocyclic compounds predominate, particularly triazine derivatives, tetrazoles, and benzothiazoles. Cytotoxicity assessment demonstrated that the extracts and fractions displayed low inhibitory activity against MCF-7 cells, with the strongest effect observed at an IC50 value of 234.8782 ppm, which remains above the accepted threshold for significant cytotoxic activity. Although the activity against MCF-7 cells was limited, further investigation involving other cancer models and isolation of active constituents is necessary to better understand and potentially enhance the biological activity of C. latifolia leaf.
Co-Authors Aditya K. Karim Aditya K. Karim Adriansyah, Fikri Affandi, Azhar Kholiq Afnur Imsya Aldes Lesbani Ali Djamhuri Amin Ali Mubarok Amin Rejo Andika Puspita Dewi Annisa Kemala Tasya Arum Setiawan Arum Setiawan Arum Setiawan Arum Setiawan Aryani, Robeah Astri Indah Lestari Ayu Nursafitri Ayu Safitri Chatrin Yohana Simamora Dedek Kurniawan Deni Julius Destia Maharani Destri, Erin Dewi Lisandra Doni Setiawan Dwi Asmono Dwi Septiawati, Dwi Eddy Ibrahim Edward Saleh Eka Haryati Yuliany Elfita Elfita Elisa Nurnawati Elisa Nurnawati Elvi Rusmiyanto Pancaning Wardoyo, Suci Lestari, Mukarlina, Elyani Ami Endri Junaidi Endro Sastro cahyono Enggar Patriono Ervina Indrayani Ervina Indrayani Erwin Nofyan Evi Yuliza Evi Yuliza Evi Yuliza, Evi Fidella Oktariana Fikri Adriansyah Fikri Adriansyah Fikri Adriansyah Fitri Maya Puspita Fitri Maya Puspita Fitri Maya Puspita Fitri Maya Puspita Harvianti, Yuniar Hary Widjajanti Hary Widjajanti hasana, nurdiah Helena Valenta Br Kemit Heni Yohandini Hernanda, Eggyana Deri Hikayati I Gusti Wayan Murjana Yasa Indra Yustian Indrawati Indrawati Irmeilyana Juswardi Juswardi, Juswardi Lestari, Astri Indah Lestari, Margareta Sri Maretasari, Giri Margareta Sri Lestari Margareta Sri Lestari, Margareta Sri Maya Puspita, Fitri Melisyah, Melisyah Melwita, Elda Mery Hasmeda Muhammad Habiburrahman Muharni Muharni Muharni, . Mustafa Kamal Nabila Aprianti Nanda Lia Putri Sari Negara, Zaidan Panji Ngudiantoro . Nina Tanzerina Nirwana, Rahma Julia Nita Aminasih Nita Aminasih Nita Aminasih Novira, Sandra Nur Arifah Nuriessa Aputri, Farah Nursela, Dewi Parwanti, Sri Permata, Ending Pratiwi, Putri Rizki Putra Bahtera Jaya Bangun Putra Bahtera Jaya Bangun Putra BJ Bangun, Putra BJ R. Rugayah Rahmat Pratama Rahmat Pratama Rahmat Pratama, Rahmat Ranti Sawitri Ratih Wijayanti, Ratih Reza Andeka Rina S. Kasiamdari Rina S. Kasiamdari Rina Sri Kasiamdari Rizka Aniza Robeah Aryani Rosmania, Rosmania Rugayah Rugayah Rupiah Rupiah Rupiah S. Santosa Salni Salni Salni Salni Salni Santika, Baitha Santosa . Santosa Santosa Sarno Sarno Sarno Sarno Sarno Sarno Sarno Sarno Singgih Tri Wardana Singgih Tri Wardana Sisca Octarina Sisca Puspita Sepriliani Siti Indah Oktaviani Siti Indah Oktaviani Siti Suzlin Supadi Suheyanto Suheryanto Sulaksono, Gogoh Syafrina Lamin, Syafrina Tri Handayani Venty Wendra, Fahmi Wijaya, Alfan Windusari, Yuanita Yadi Oktariansyah Yolanda Fitria Yuanita Windusari Yuanita Windusari Yuanita Windusari Yuanita Windusari Yuanita Windusari Yuanita Windusari Yulia Anisawati Yuliany, Eka Haryati Zahrial Effendi Zaidan P Negara Zulkifli Dahlan Zulkifli Dahlan Zulkifli Dahlan