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KEPADATAN VEKTOR DEMAM BERDARAH DENGUE DI PERUMNAS SITEBA PADANG TAHUN 2008 Nuzulia Irawati
Majalah Kedokteran Andalas Vol 34, No 2 (2010): Published in August 2010
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (273.97 KB) | DOI: 10.22338/mka.v34.i2.p132-137.2010

Abstract

AbstrakDemam Berdarah Dengue (DBD) masih merupakan masalah kesehatan masyarakat terpenting di Indonesia. Penyakit ini disebabkan oleh virus dengue, yang disebarkan melalui gigitan nyamuk Aedes aegypti sebagai vektor utama. Penyakit ini menyebar bersamaan dengan peningkatan mobilitas penduduk, kepadatan penduduk dan transportasi. Penyelidikan telah dilakukan dalam rangka memperoleh jawaban tentang kepadatan vektor DBD di Perumnas Siteba menggunakan metode penelitian Survey Deskriptif (Cross Sectional). Dalam hal ini, 100 buah rumah digunakan sebagai sampel sedangkan teknik pengambilan sample adalah Multi Stage Random Sampling. Hasil yang didapatkan 33% rumah dan 20.7% kontainer positif mengandung larva aedes dan 100% berupa Aedes aegypti. Kesimpulan dari penelitian ini adalah kepadatan vektor DBD di Perumnas Siteba Padang cukup tinggi dengan ratio 3: 1, dengan vektornya Aesdes aegypti. Hal ini dapat dilihat dari salah satu rumah yang positif larva Aesdes aegypti.Kata lunci : Aedes aegypti, Dengue Haemorrhagic fever (DHF)AbstractDengue Hemorrhagic fever (DHF) is still an critical community health problem in Indonesia. This disease is caused by Dengue Virus, which is spread through Aedes aegypti’s bite as the main vector. This disease spread together along with the increasing of people’s mobiliy, the population density and the transportation. The research has been done in order to get the description of the density 0f DHF vector in Perumnas Siteba by using Descriptive Survey (Cross Sectional) research method. In this case, one hundred houses are used as the sample, while the technique of taking the sample is in Multistage Random Sampling. The result 0f above 33% house and 20.7% the containera, positively with Aedes larva and almost 100% vector’s species are Aedes aegypti. In this respect, it can be concluded that the density of DHF Vector in Perumnas Siteba Padang is ther high, in ratio 3:1. It can be seen from one of three houses are positive with Aedes aegypti larvae.Key word : Aedes aegypti, Dengue Haemorrhagic fever (DHF)ARTIKEL PENELITIAN
PENGARUH INFEKSI CACING USUS TERHADAP EKSPRESI INTERFERON GAMMA SERUM PASKA PEMBERIAN IMUNISASI TETANUS TOKSOID Selfi Renita Rusjdi; Hafni Bachtiar; Nuzulia Irawati
Majalah Kedokteran Andalas Vol 36, No 1 (2012): Published in April 2012
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (292.637 KB) | DOI: 10.22338/mka.v36.i1.p87-95.2012

Abstract

AbstrakPenyakit cacing usus masih merupakan masalah kesehatan di Indonesia. Penyakit ini mempunyai dampak merugikan pada manusia terutama pada anak. Selain menimbulkan gangguan gizi, cacing ini juga menimbulkan penurunan respon terhadap antigen. Penurunan respon ini terjadi akibat respon polarisasi Th2 pada infeksi cacing usus. Tetanus toksoid yang diberikan dalam Bulan Imunisasi Anak Sekolah merupakan antigen sebagai penginduksi respon sel T. Penelitian ini bertujuan untuk mengetahui pengaruh infeksi cacing usus terhadap ekspresi IFN-γ serum paska pemberian tetanus toksoid.Lokasi penelitian dilakukan di Kecamatan Batang Anai Padang Pariaman dengan menggunakan rancangan potong lintang. Populasi dalam penelitian ini adalah murid kelas 2 dan kelas 3 SDN 08 dan SDN 22 Batang Anai Padang Pariaman. Status kecacingan didapatkan dari pemeriksaan feses metoda Kato-Katz. Kadar IFN-γ serum didapatkan dari pemeriksaan serum metode ELISA. Pengolahan dan analisa data menggunakan uji Kolmogorov-Smirnov.Hasil penelitian pada kelompok yang terinfeksi cacing usus didapatkan rerata kadar IFN-γ adalah sebesar 0,15 ± 0,16 pg/ml dan kelompok kontrol didapatkan sebesar 1,4 ± 1,02 pg/ml. Terdapat perbedaan bermakna kadar IFN-γ antara kelompok yang terinfeksi cacing usus dengan kelompok kontrol. (p< 0,05).Dari hasil penelitian dapat disimpulkan bahwa infeksi cacing usus dapat menekan ekspresi IFN-γ terhadap pemberian tetanus toksoid.Kata kunci: Cacing Usus, Tetanus Toksoid, Interferon gamma (IFN-γ)AbstractIntestinal helminthiasis is still unsolved problem in Indonesia. Children are particularly vulnerable to get health problem caused by those infection. The health problems are malnutrition and nowadays impairment immune response of antigen. The impairment is caused by Th2 polarized response. Tetanus toksoid which is annually given to elementary school children in Bulan Imunisasi Anak Sekolah isARTIKEL PENELITIAN88known as T cell strong inducer after vaccination.The aim of this study was to determine the influence of intestinal helminthiasis on serum IFN-γ expression after administered tetanus vaccination.This research is cross sectional study and it was conducted in Kecamatan Batang Anai Padang Pariaman. Population of this study are 2 nd and 3 rd grade of elementary school student in SDN 08 and SDN 22. Intestinal helminthiasis status was taken by Kato – Katz methode of fecal examination. Serum IFN-γ was analyzed by ELISA methode. The data was analyzed by Kolmogorov-Smirnov test.Mean of serum IFN-γ in intestinal helminthiasis group are 0,15 ± 0,16 pg/ml and uninfected control group are 1,4 ± 1,02 pg/ml. There was significant difference on serum IFN-γ level in intestinal helminthiasis group and uninfected control group (p<0,05).This study concluded that intestinal helminthiasis may impair serum IFN-γ expression to tetanus vaccination.Key word: intestinal helminthiasis, tetanus toxoid, interferon gamma (IFN-γ)
Ekspresi Tumor Necrosis Factor-Alfa (TNF-α) dan Interleukin-10 (IL- 10) pada Infeksi Malaria Falciparum Lili Irawati; Nusirwan Acang; Nuzulia Irawati
Majalah Kedokteran Andalas Vol 32, No 1: April 2008
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (410.991 KB) | DOI: 10.22338/mka.v32.i1.p16-28.2008

Abstract

AbstrakMalaria masih menjadi masalah kesehatan di dunia terutama negara tropis karena angka kesakitan dan kematiannya yang tinggi. Infeksi Plasmodium falciparum ini dapat menimbulkan gejala yang berat sampai kematian. Perbedaan perjalanan penyakit pada masing-masing individu salah satunya dipengaruhi oleh sistim imun. Di antara zat yang ikut berpengaruh pada imunitas malaria adalah TNF-α dan IL-10, yang dihasilkan oleh sistim pertahanan tubuh terhadap parasit ini. Tujuan penelitian ini adalah untuk mengetahui ekspresi TNF-α dan IL-10 pada infeksi malaria falciparum, menggunakan rancangan explanatory secara cross sectional, dan melibatkan 25 penderita malaria falciparum dengan umur berkisar 14 – 60 tahun. Kadar TNF-α dan IL-10 dianalisis dengan metoda enzyme-linked immunosorbent assay (ELISA), dan hasil analisis dinyatakan bermakna bila didapatkan p < 0,05. Penelitian menunjukkan adanya peningkatan kadar TNF-α dengan rerata 283,10 ± 267,72 pg/ml dan peningkatan kadar IL-10 dengan rerata 196,99 ± 131,94 pg/ml pada penderita malaria falciparum, yang dalam keadaan normal tidak terdeteksi. TNF-α berkorelasi positif dengan IL-10 (r = 0,491; p > 0,05), tapi berkorelasi negatif dengan kadar hemoglobin (r =-0,189; p > 0,05). IL-10 berkorelasi positif dengan kadar hemoglobin (r= 0,134; p > 0,05). Terhadap parasitemia, TNF-α berkorelasi positif (r=0,036; p > 0.05), namun IL-10 berkorelasi negatif (r = -0,043 dan p>0,05). Dari penelitian ini dapat disimpulkan bahwa infeksi malaria falciparum berpengaruh terhadap peningkatan kadar sitokin TNF-α dan IL-10.Kata kunci : TNF α – IL 10 – malaria falciparumAbstractMalaria is still a universal health problem, especially in tropical countries because of its high morbidity and mortality rates. Infection by Plasmodium falciparum could result in severe symptoms or even death. Differences in pathogenesis among affected individuals are affected by many factors, and the immune system is one of them. Among substances involved in the malarial immunity is TNF-α and IL-10, produced by the body's defense system as the reaction to the parasite. The objective of this study is to find expression of TNF-α and IL-10 on falciparum malaria infection, using an explanatory cross-sectional design, involving 25 people with falciparum malaria with age ranging from 14 to 60 years. The presence of TNF-α and IL-10 wereARTIKEL PENELITIAN17analyzed using enzyme linked immunosorbent assay (ELISA), and significant values considered at p < 0.05. The results show that there are increased rate of TNF-α with average 283.10 ± 267.72 pg/ml, and increased rate of IL-10 with average 196.99 ± 131.94 pg/ml among people with falciparum malaria, while in normal circumstances they are not detected. There is a positive correlation of TNF-α with IL-10 (r=0.491; p>0.05), but negative correlation with the rate of hemoglobin (r=-0189; p>0.05). IL-10 correlated positively with the rate of hemoglobin (r=0.134; p>0.05). TNF-α is positively correlated with parasitemia (r =0.036; p>0.05), but IL-10 is negatively correlated (r =-0043 and p>0.05). The results from this study conclude that falciparum malaria infection increases of TNF-α and IL-10 cytokine.Keywords: TNF α – IL 10 – falciparum malaria
EFEKTIVITAS MEDIA POP-UP CARD TERHADAP PENGETAHUAN KESEHATAN GIGI DAN MULUT ANAK USIA 8-9 TAHUN Rizki Dwi Lestari; Nuzulia Irawati; Murniwati Murniwati
Andalas Dental Journal Vol 5 No 1 (2017): Andalas Dental Journal
Publisher : Faculty of Dentistry Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (92.529 KB) | DOI: 10.25077/andalas dent. j..v5i1.68

Abstract

Dental caries is a dental problem that often affects children. One of oral and dental health problems etiology is behavioral or negligence factor to the oral and dental health. This happens due to lack of knowledge about the importance of maintaining oral and dental health, especially in children. Attractive learning media is necessary to improve the knowledge about oral and dental health. The aim of this study is to determine the effectiveness of pop-up card media toward oral and dental health knowledge of 8-9 years old children. This study used a non-equivalent control group design. Pre-test, treatment and post-test were conducted. Sampling was conducted by random and simple sampling, then the samples were divided into two groups, 23 third grade elementary school students of SDN 23 Echoes Jati Padang were included to the experimental group. This group was taught with oral and dental health education by using pop-up card media and 23 others were included into control group taught with oral and dental health education without pop-up card media. Analysis of the data was conducted using McNemar test. Statistical test results using McNemar test showed a significant increase in the knowledge. Pop-up card media effectively improved the knowledge of experimental group with p value of 0.000 (p <0.05). Based on the research that has been conducted, it can be concluded that pop-up card media is effective to improve knowledge of 8-9 years old children. Keywords:Children, Pop-up Media, Knowledge
EFFECTIVENESS OF 5% GUAVA LEAF (Psidium guajava Linn) EXTRACT OF WHITE FRUIT VARIANT TO DECREASE LEVELS OF Volatile Sulfur Compounds (VSCs) IN HALITOSIS SUFFERERS Melina Vania Elian; Nuzulia Irawati; Surya Nelis
Andalas Dental Journal Vol 1 No 2 (2013): Andalas Dental Journal
Publisher : Faculty of Dentistry Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (475.957 KB) | DOI: 10.25077/adj.v1i2.164

Abstract

Halitosis is a general term used to describe the bad breath coming out of the oral cavity. Volatile Sulfur Compounds (VSCs) are a major component causes of halitosis, formed from the break down of protein substrate by gram-negative anaerobes such as Porphyromonas gingivalis, Tanerella forsythia, Fusobacterium nucleatum, Prevotella intermedia and Treponema denticola. Guava leaf (Psidium guajava Linn) contain high levels of quercetin compounds that can inhibit the growth of Porphyromonas gingivalis and Prevotella intermedia. This study aims to determine the effectiveness of 5% guava leaf (Psidium guajava linn) extract of white fruit variant to decrease levels of Volatile Sulfur Compounds (VSCs) in halitosis sufferers. This research method was pre-experimental which consists of 19 subjects. The guava leaf (Psidium guajava Linn) extract was made by maceration method and diluted with distiled water at 5% concentration. The levels of Volatile Sulfur Compounds (VSCs) were measured by breath checker before (pre test) and after (post test) treatment. Wilcoxon test showed that there was a significant difference between the levels of Volatile Sulfur Compounds (VSCs) before and after gargling with 5% guava leaf (Psidium guajava Linn) extract of white fruit variant (p<0,05). The conclusion of this research was 5% guava leaf (Psidium guajava Linn) extract of white fruit variant effectively decreases levels of Volatile Sulfur Compounds (VSCs) in halitosis sufferers.
Edukasi dan Skrining Penyakit Cacingan pada Siswa SDN 10 Kelurahan Lambung Bukit Eka Nofita; Hasmiwati Hasmiwati; Adrial Adrial; Nurhayati Nurhayati; Selfi Renita Rusjdi; Husnil Wardiyah; Nuzulia Irawati
Warta Pengabdian Andalas Vol 29 No 2 (2022)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.29.2.81-86.2022

Abstract

One of the primary health problems still found in Lambung Bukit Village is the high stunting rate. The incidence of stunting is influenced by many factors, one of which is intestinal worm infection (Helminthiasis). Worms that live in the intestine will interfere with the absorption of food and suck the blood of their host, causing malabsorption, malnutrition and growth disorders, which can cause stunting. Therefore, genuine efforts are needed to eradicate this helminthic disease. Department Parasitology of Medical Faculty, the Andalas University, conducted community service activities at SDN 10 Lambung Bukit to reduce intestinal worm infections in children by providing counselling, detection and treatment, and follow-up on treatment success. The counselling activity was attended by 88 students and eight teachers, with 59 samples of faeces collected. From the stool examination results, none of the worm eggs was found, but four students were positive for intestinal protozoa. Furthermore, treatment was given to these four students. Through this activity, it was expected to increase students' awareness of maintaining personal hygiene so that to reduce the incidence of helminthiasis, and help to reduce stunting rates.
The Effect of Administering Vitamin D Supplement on Blood Glucose Level in Gestasional Diabetes Mellitus Rats Meka Melani Sari; Nuzulia Irawati; Dr. Efrida
Science Midwifery Vol 9 No 1, Oktober (2020): Science Midwifery
Publisher : Institute of Computer Science (IOCS)

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Abstract

Gestational Diabetes Mellitus (DMG) occurs due to insulin resistance during pregnancy which causes glucose intolerance in various levels and hyperglycemia. The incidence of DMG in the world and in Indonesia continues to increase every year. Gestational diabetes mellitus can cause complications to the mother and the fetus both during pregnancy and after delivery. Administering vitamin D supplement can reduce blood glucose level and keep the fetal growth rate in normal limits. This study aimed to determine the effect of administering vitamin D supplement on glucose level and fetal growth rate in DMG rats. This is an experimental study with post-test only control group design in 15 pregnant rats with gestational diabetes. Samples were divided into three groups, one control group and two treatment groups which were given vitamin D supplements at a dose of 9µg/kgBW and 18µg/kgBW for 14 days. Blood glucose level examination was done by using a glucometer and the fetal growth rate was done by using an analytical balance and millimeter paper. Statistical testwas conducted by using One Way ANOVA, the significance was determined if p <0.05. Mean ± SD blood glucose levels (mg/dL) in the the control group (170.80 ± 4.147), P1 group (126.00 ± 1.581), P2 group (123.80 ± 1.924) (p 0.001). Statistically there was a significant difference in the administration of vitamin D supplements on blood glucose levels and there was no significant difference in fetal growth rates in DMG rats. The conclusion of this research is that effect administration of vitamin D supplements on blood glucose levels and it does not affect fetal growth rates in DMG rats.
Analysis on the Relation of Contraception Selection Towards Perceptions of Side Effects in Couples of Reproductive Age in the Working Area of Lubuk Buaya Public Health Center in Lubuk Buaya Sub-District, Padang City Sandra Ilona; Nuzulia Irawati; Aladin Aladin
Science Midwifery Vol 10 No 1, October (2021): Science Midwifery
Publisher : Institute of Computer Science (IOCS)

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Abstract

Family Planning Program (KB) is one of the programs used to cope with the increasing population. The purpose of the Family Planning Program (KB) is to improve the quality of the population through birth control, to reduce mortality, and to improve the quality of the family planning program, one of which is by using the Long-Term Contraceptive Method (MKJP). Side Effects on Couples of Reproductive Age in the Working Area of the Lubuk Buaya Public Health Center, Lubuk Buaya Sub-district, Padang City.This study used a cross sectional design. The research population was all couples of reproductive age who were in the working area of the Lubuk Buaya Sub-district Public Health Center, Padang City who received contraceptive services. The sample of this study was 108 respondents of reproductive age couples who had received family planning services. Data were collected by using questionnaires and data were analyzed by using chi-square test and logistic regression test. The results of this study found that there was a significant relation between perceptions of side effects on the contraception selection (p = 0.016) The conclusion of this study is that there is a relation between perceptions of the side effects on contraception selection.
Correlation between Zinc and Folic Acid Intake with Hemoglobin Levels in Pregnancy Eka Darmayanti Putri Siregar; Arni Amir; Nuzulia Irawati
Science Midwifery Vol 10 No 5 (2022): December: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v10i5.896

Abstract

The deficiency of micronutrients and anemia are nutritional problems in pregnancy. WHO in 2019 and Riskesdas in 2018 reported that anemic pregnant women in Indonesia were 44.2% and 48.9%. Public Health Service also reported there was an increased prevalence of this problem in West Sumatra and Padang City in 2019 which was 18.1% and 11.2%. Micronutrient deficiency affected the hemoglobin (Hb) level, which is one of the indicators marking anemia in pregnancy. The objective was to determine the correlation between zinc and folic acid with hemoglobin levels in the third trimester of pregnancy. This analytical cross-sectional research was held in the Health Center and laboratory of Lubuk Kilangan on May-July 2022. The population and samples were 64 third-trimester pregnant women with total sampling. Intake data were collected through interviews using the Food Frequency Questionnaire (FFQ). Hemoglobin levels were examined by a hematology analyzer. Pearson correlation was used to identify the correlation of the variables (P< 0.05) . The mean levels of zinc and folic acid intake and hemoglobin levels were 7.35 mg, 215.56 mcg, and 11.08 g/dL. There was a positive correlation between zinc (p=0,015) and folic acid (p=0.004) with hemoglobin levels in the third trimester of pregnancy.
Identification of Intestinal Protozoa in Adults in Pasie Nan Tigo Sub-Distric Koto Tangah Padang Genia Alda Fitria; Nuzulia Irawati; Firdawati Firdawati
Journal of Agromedicine and Medical Sciences Vol 8 No 3 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v8i3.29697

Abstract

Intestinal protozoan infection is one of the leading causes of morbidity and mortality worldwide. However, it is difficult to estimate the true problem of protozoal infections because cases are under-reported. This study aimed to identify intestinal protozoa in healthy adults. This study used a categorical descriptive research design and used a multistage random sampling technique. This research was conducted in Pasie Nan Tigo, Koto Tangah, Padang from July 2020 to December 2021 with a total of 61 samples obtained. Furthermore, the samples were examined using the direct stool examination method and with modified Ziehl-Neelsen staining. The results of this study were obtained, from 61 subjects the most age group was 45-49 years (27.9%), the most gender was female (88.5%), and the incidence of intestinal protozoal infection was 3.3% where only Blastocystis hominis found. The vacuole stage and cyst stage were found to be 50%, respectively. All samples examined were single infection. The conclusion of this study is that Blastocystis hominis infection is still found in healthy adults in Pasie Nan Tigo, Koto Tangah, Padang. Therefore, supportive therapy and measures to prevent infection transmission need to be carried out so that the incidence and morbidity rates can be reduced. Keywords: Intestinal protozoa infections, healthy adult
Co-Authors Abdiana Abdiana Adeline Sacharissa Firdaus Adrial Adrial Adrial Adrial Afriwardi Afriwardi Afrizal Afrizal Ahlul Zikri Aladin Aladin Almurdi Almurdi Alvarino Alvarino Amir, Arni Amir, Arni Anandila Maulina Arni Amir Aswiyanti Asri Auwilla Marta Tasman Darmadi Darmadi Darmayanti Siregar Dedi Afandi Delmi Sulastri Delmi Sulastri Desmawati Desmawati Djong Hon Tjong Dr. Efrida Efrida Efrida Eka Nofita Elli Firdamila Ellyza Nasrul Elmatris Sy Endang Suriani Ennesta Asri Ermawati Ermawati Evareni, Lisma Fadjar Goembira Fajrul Ikhsan Faroliu, Goldha Fathiyyatul Khaira, Fathiyyatul Febby Arrahmi Fika Tri Anggraini Firdamila, Elli Firdawati Firdawati fitria ningsih Genia Alda Fitria Hafni Bachtiar Harminarti, dr Nora Hasmiwati Hildya Kusmi Hillbertina, Noza Hirowati Ali Husna Yetti Husnil Kadri Husnil Wardiyah Huvaid, Sevilla Ukhtil Ida Rahma Burhan Ida Rahmah Burhan Ilmiawati, Ilmiawati Ilmiawati, Ilmiawati Irma Yulianti Johanes C Mose Joserizal Serudji Lestari, Rahmi Lili Irawati Machdawaty Masri Mareza Dwithania Meka Melani Sari Melina Vania Elian Mohamad Reza Mohammad Tegar Indrayana Murniwati Murniwati Mustika Dewi Naufal, Daffa Ahmad Netti Suharti Nora Harminarti Noza Hilbertina, Noza Nur Afrainin Syah Nur Indrawaty Lipoeto Nurhayati Nurhayati Nurhayati Nurhayati Nursyirwan Effendi, Nursyirwan Nusirwan Acang Putri Gemala Sari Putri, Salsa Utami Rahayu, Yanti Randi Septiah Hendri Rauza Sukma Rita Riche Anggresti Rika Susanti Rima Semiarty Rizanda Machmud Rizka Yunidha Anwar Rizki Dwi Lestari Rosfita Rasyid Roza Kurniati Kurniati Sandra Ilona Selfi Renita Rusjdi Seto, Astari Siregar, Eka Darmayanti Putri Siti Nurhajjah Sitti Monica Astrilia Ambon Sri Wahyuni Handayani Sri Wahyuni Handayani, Sri Wahyuni Sukri Rahman Surya Nelis Sutrisna, Betti Endang Syahputra, Roni Eka Syawal Andika Putra Teguh Imana Nugraha TEVINA EDWIN Tivany Edwin Tofrizal Tuti Gusra Veri Syah Putra Weni Mulyani Yanwirasti Yanwirasti Yessi Pertiwi Yuniar Lestari Yuniar Lestari Yusrawati Yusrawati