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Jusak Nugraha
Clinical Pathology Department, Dr. Soetomo Hospital Surabaya Institute Of Tropical Disease, Universitas Airlangga Surabaya
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Veterinary Other

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Journal : Media Penelitian dan Pengembangan Kesehatan

 1 
Dyslipidemia in Chronic Kidney Disease Patients at Dr. Soetomo Hospital Surabaya Siti Rahmawati; Jusak Nugraha; Edhi Rianto
Media Penelitian dan Pengembangan Kesehatan Vol 31 No 1 (2021)
Publisher : Sekretariat Badan Penelitian dan Pengembangan Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/mpk.v31i1.3917

Abstract

Epidemiological studies report that patients with chronic kidney disease (CKD) have a higher risk of mortality from cardiovascular disease than the general population. Previous studies have shown that dyslipidemia is thought to play a role in the development of atherosclerosis in patients with CKD. Dyslipidemia is known to be common in CKD patient population, but shows a diverse patterns in various CKD patient populations. This study aimed to analyze the lipid profile and lipid ratio in CKD patients at Dr. Soetomo Hospital Surabaya for the period 2016-2017. This cross-sectional study was conducted through retrospective observation of the medical records of CKD patient at the Kidney-Hypertension Polyclinic of Dr. Soetomo Hospital Surabaya in the 2016-2017 period. A total of 68 research subjects were analyed in this study. Most of the study subjects were male (68%) and the median age was 54 years. Almost 70% of the study subjects had CKD stage 5. Increased levels of total cholesterol and triglyceride were found in 37% of the study subjects. Meanwhile, a decreae in HDL-cholesterol levels and an increase in LDL-cholesterol and non-HDL-cholesterol levels were found in 60% of the study subjects. The mean value of total cholesterol, LDL-cholesterol, and non-HDL-cholesterol levels in the female group was siginificantly higher based on statistical calculations (p0.05). Most of the study subjects were predicted to be at risks for developing cardiovascular disease based on the calculation of several lipid ratios. The incidence of dyslipidemia in population is known to be higher than in the general population. Decreased HDL-cholesterol, increased LDL-cholesterol, and non-HDL-cholesterol are the most common forms of dyslipidemia in population studies. Abstrak Studi epidemiologi melaporkan bahwa pasien penyakit ginjal kronis memiliki risiko mortalitas akibat penyakit kardiovaskular yang lebih tinggi dibandingkan populasi umum. Studi sebelumnya menunjukkan bahwa dislipidemia diduga turut berperan terhadap terjadinya atherosklerosis pada pasien penyakit ginjal kronis. Dislipidemia diketahui umum ditemukan pada populasi pasien penyakit ginjal kronis namun menunjukkan pola yang bervariasi pada berbagai populasi pasien penyakit ginjal kronis. Studi ini bertujuan untuk menganalisis profil lipid dan rasio lipid pada pasien penyakit ginjal kronis di RSUD Dr. Soetomo Surabaya periode 2016-2017. Studi cross-sectional ini dilakukan melalui pengamatan retrospektif terhadap catatan rekam medis pasien penyakit ginjal kronis di Poliklinik Ginjal-Hipertensi RSUD Dr. Soetomo Surabaya pada periode 2016-2017. Sebanyak 68 subjek penelitian dianalisis dalam penelitian ini. Sebagian besar subjek penelitian berjenis kelamin laki-laki (68%) dan nilai median usia pada subjek penelitian mencapai 54 tahun. Sebagian besar subjek penelitian memiliki penyakit ginjal kronis stadium 5 (70%). Peningkatan kadar kolesterol total dan trigliserida ditemukan pada sekitar 37% subjek penelitian. Sedangkan penurunan kadar HDL-kolesterol dan peningkatan kadar LDL-kolesterol serta non HDL-kolesterol ditemukan pada sekitar 60% subjek penelitian. Nilai rerata kadar kolesterol total, LDL-kolesterol, dan non HDL-kolesterol pada kelompok berjenis kelamin perempuan secara signifikan lebih tinggi berdasarkan perhitungan statistika (p0.05). Sebagian besar subjek penelitian diprediksi memiliki risiko untuk mengalami penyakit kardiovaskular berdasarkan perhitungan beberapa rasio lipid. Insiden dislipidemia pada studi populasi diketahui lebih tinggi dibandingkan populasi umum. Penurunan HDL-kolesterol, peningkatan LDL-kolesterol, dan non HDL-kolesterol merupakan bentuk dislipidemia yang paling umum ditemukan pada studi populasi.
Co-Authors Abdul Hafid B Agung Dwi Wahyu W Agung Dwi Wahyu Widodo Agustiningrum, Indah Akhmad Setyo Rahman aminuddin, mohammad Anak Agung Istri Sri Wiadnyani Anita Budiarti Anna Roosdiana Anton Yuntarso Aryati Aryati Aryati Aryati Ashon Sa'adi Ashon Sa’adi Ashon Sa’adi Awalia Awalia Ayu Imamatun Nisa Bambang Purwanto Bastian Bastian Bastian Bastian Beatrix, Stephanie Besin, Valentinus Betty Agustina Betty Agustina Tambunan Buana, Dwi Candra Budi Prasetyo Budi Utomo Budiutari, Ni Nyoman Budy, Theresia Indah Callixte, Cyuzuzo Caroline Caroline Ch. Destri Wiwis Wijayanti Christina Destri Citra Indah Setyaningrum Cynthia Cynthia Cynthia Cyuzuzo Callixte Darmadi, Epriyanto T Dheasy Herawati Diyan Wahyu Kurniasari Djoko Agus Purwanto Dominicus Husada Dwi Aris Agung Nugrahaningsih Dwi Liliek Kusindarta Dwiyanti Puspitasari, Dwiyanti Eddy Mart Salim Eddy Mart Salim Eddy Mart Salim Eddy Mart Salim, Eddy Mart Edhi Rianto Elok Budi Retnani Elvan Dwi Widyadi Erfina Lim Erna R Tobing Esthy Poespitaningtyas Febtarini Rahmawati Ferdy R. Marpaung Ferdy Royland Marpaung Foe, Kuncoro Francisca Srioetami Tanoerahardjo Francisca Srioetami Tanoerahardjo Fransisca Srioetami Tanoerahardjo Fransisca Srioetami Tanoerahardjo Fransiska Fransiska Fransiska Sri Oetami Gede Arie Wijaya Handayani, Luh Putu Trys Monika Hans Kristian Nugraha, Hans Kristian Hantoro Gunawan Hari Basuki Notobroto Hari Setiono Hartono Kahar, Hartono Hendy Wijaya Herin Mawarti Heru Setiawan Hery Priyanto Hevi Wihadmadyatami Holland Lydia Marpaung Huda Shalahudin Darusman I Made Andika Bara Kusuma Idha Kusumawati Ilham Ilham Irvan Ipandi Januarti, Catur Ifda Joewono Soeroso John Wiwin Julious Julious julious, julious Kasiyati, Menik Kemas Ya'kub Rahadiyanto Kemas Ya'kub Rahadiyanto Kemas Ya’kub Rahadiyanto kurniati, nova Lisa Soegianto Lumempouw, Silvia Luminto, Dian Lutfi Dewanda Nugroho M. Aminuddin M. Aminuddin M. Irsan Saleh Maya E. Roring Meiti Muljanti, Meiti Mohammad Aminuddin Mohammad Hasan Machfoed Muhammad Amin Muhammad Amminuddin Muhammad Hamdan Muhammad Irsan Saleh Muhammad Nazarudin Munawaroh Fitriah Myrza Elita Nico Jafet Ningrum, Emilna Mega Ninik Asmaningsih Soemyarso Notopuro, Paulus Budiono Nova Kurniati Nova Kurniati Nova Kurniati Noviana, Rachmitasari Nugraha, Hans K Nur Hayati Nur Lailatul Fadhilah Oetami, Fransisca Sri Oryza Chrisantia Patria Dewi Pande Pratama, Dyah Ayu Oktaviani A Prihantika S., Sabrina Pudji Lestari Purwanta, Marijam Purwoko, Agus Puspitasari, Yessy Putri, Indah Aprianti Rahadiyanto, Kemas Ya'Kub Rahajuningsih Dharma Rahma Indah Pratiwi Rendy, Achmad Nur Rifa’I, Muh Husni Risky V. Prasetyo Roedi Irawan Rusli, Musofa Ryzky Widi Atmaja S. Soedarsono S.Pd. M Kes I Ketut Sudiana . Sabri Prihantika Sabrina Prihantika Saleh, M Irsan Saputra, Angky Saputri, Agatha Efrad Senny Yesery Esar Setiawan, Lidwina Tri Kristanti Shahzad Shoukat Sheila Clarissa Shoukat, Hamad Shoukat, Shahzad SILMI MARIYA Silvia F. Lumempouw Sinansari, Restry Siti Nur Husnul Yusmiati Siti Rahmawati Soedarsono Soedarsono Soedarsono Soedarsono Soelistijo, Soebagijo Adi SP Edijanto Srikanth Karnati Süleyman Ergün Susi Oktaviani Tanoehardjo, Francisca Srioetami Tanoehardjo, Francisca Srioetami Tanoerahardjo, Francisca Srioetami Tedja, I G.A. Wiradari Theresia Indah Budhy Sulisetyawati Triagung Ruddy Tuyishimire Irene Utariani, Arie UUS SAEPULOH Wahyu Dewi Tamayanti, Wahyu Dewi Wahyu Setiani Wibowo Wahyu Setiani Wibowo Winthoko, Eka Nora Vitaloka Aprilia Putri Wulandari, Dian Novita Wuryanto Hadinugroho Yetti Hernaningsih Yoes Prijatna Dachlan Yudy Tjahjono Yufita Ratnasari Wilianto Yulia Nadar Indrasari Zen Hafy