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All Journal HAYATI Journal of Biosciences Jurnal Ilmu Dasar Jurnal Penelitian Sains (JPS) Jurnal Natur Indonesia Alchemy Jurnal Penelitian Kimia Majalah Obat Tradisional CHEMPUBLISH JOURNAL JIMKesmas (Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat) Jurnal Penelitian Sains (JPS) IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Jurnal Penelitian Sains ALCHEMY Jurnal Penelitian Kimia Indonesian Journal of Chemistry Preventif Journal Martabe : Jurnal Pengabdian Kepada Masyarakat JSFK (Jurnal Sains Farmasi & Klinis) JURNAL PENDIDIKAN TAMBUSAI Sainmatika: Jurnal Ilmiah Matematika dan Ilmu Pengetahuan Alam Jurnal Pengabdian Magister Pendidikan IPA Molekul: Jurnal Ilmiah Kimia Jurnal Abdi Insani PUBLIKASI PENELITIAN TERAPAN DAN KEBIJAKAN JPK: Jurnal Proteksi Kesehatan Jurnal Abdidas Miracle Journal Of Public Health (MJPH) Jurnal Pengabdian Masyarakat Indonesia Education Enthusiast : Jurnal Pendidikan dan Keguruan Jurnal Altifani Penelitian dan Pengabdian kepada Masyarakat JKP (Jurnal Kajian Pemerintah: Journal of Government Social and Politics) Makara Journal of Science Jurnal Pepadu Innovative: Journal Of Social Science Research Journal of Local Therapy Journal of Security, Computer, Information, Embedded, Network and Intelligence System Indonesian Technology and Education Journal Jurnal Kefarmasian Indonesia PITIMAS: Journal of Community Engagement in Health
Muharni Muharni
Department Of Chemistry, Faculty Of Mathematics And Natural Sciences , Sriwijaya University, Jl. Raya Palembang Prabumulih Km 32, Indralaya, Ogan Ilir, South Sumatera 30662
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Journal : HAYATI Journal of Biosciences

 1 
Identification of New Lactone Derivatives Isolated from Trichoderma sp., An Endophytic Fungus of Brotowali (Tinaspora crispa) . ELFITA; . MUNAWAR; . MUHARNI; MASTUR ADHY SUDRAJAT
HAYATI Journal of Biosciences Vol. 21 No. 1 (2014): March 2014
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (962.477 KB) | DOI: 10.4308/hjb.21.1.15

Abstract

Endophytic fungi is a rich source of novel organic compounds with interesting biological activities and a high level of structural diversity. As a part of our systematic search for new bioactive lead structures and specific profiles from endophytic fungi, an endophytic fungus was isolated from roots of brotowali (Tinaspora crispa), an important medicinal plant. Colonial morphological trait and microscopic observation revealed that the endophytic fungus was Trichoderma sp. The pure fungal strain was cultivated on 7 L Potatos Dextose Broth (PDB) medium under room temperature  (no shaking) for 8 weeks. The ethyl acetate were added to cultur medium and left overnight to stop cell growth. The culture filtrates were collected and extracted with EtOAc and then taken to evaporation. Two new lactone derivatives, 5-hydroxy-4-hydroxymethyl-2H-pyran-2-one (1) and (5-hydroxy-2-oxo-2H pyran-4-yl) methyl acetate (2) were obtained from the EtOAc extracts of Trichoderma sp. Their structures were determined on the basic of spectroscopic methods including UV, IR, 1H-NMR, 13C-NMR,  HMQC, and HMBC.
Co-Authors . ELFITA . MUNAWAR Abd. Rasyid Syamsuri Abdullah Abdullah Ade Oktasari Adriansyah, Fikri Afnidar Agusreni Agus Purwoko Aminah Aminah Aminu, Nurmin Aminudin Bama, Akhmad Amsina, Nuryani Anak Agung Istri Sri Wiadnyani Ananda, Dea Ani Sarah Arianti, Novi Sagita Arif Fadhilah, Arif At panagan At panagan Awaliah, Widiarti Azriani, Yuni Bahri, Usman Bana, Akhmad Aminuddin Budiono Budiono Candra Candra, Putra Setia Aji Carissa, Restri Diah Cenora, Cindy Dachariyanus Dachariyanus Dachrianus Dachrianus Dachriyanus Dasril Basir Deswari, Sri Devi Savitri Effendy, Devi Savitri Dewi Fatmarani Surianto Dewi Rahayu Dian Rianita Didi Pratama Dwi Anjar Susanti Elfita Elfita . Elfita Elfita Elfita Elfita Elfita Elfita Elfita Elfita Elfita Elfita Elfita Elfita Elfita Elfita Elfita Elfita Elfita Elfita Elisa Nurnawati Eliza Eliza Eliza Eliza Emil Pertiwi Erni Erni Fajri, Riyadhul Fajri, Ryadhul Feriska Feriska Ferlinahayati Ferlinahayati Fitri Fitri Fitrya . Fitrya Fitrya Fitrya Fitrya Fitrya Fitrya Fitrya Fitrya Fitrya Fitrya Gemini, Pra Ghaniya, Fahdelaa Gusti Pratiwi Hadir Kaban, Hadir Harmida Harmida Hary Widjajanti Heni Yohandini Husein Hernadi Bahti Huzaifah, Huzaifah I Gusti Bagus Wiksuana Indah, Tri Irwan Irwan Jorena Jorena, Jorena Julinar Julinar Julinar Julinar Julinar Jurnal Pepadu Juswardi Juswardi, Juswardi Khakim, Mokhamad Yusup Nur Laila Hanum Lenny Anwar Lily Restusari Listina, Yuli Mardiyanto Mardiyanto Maretha Kobaywan Maretha Kobaywan Maria, Tri Anna Marini . Maryadi Maryadi Maryadi Maryadi MASTUR ADHY SUDRAJAT Masyita Masyita Miksusanti Miksusanti Milanti Okta Ruliza Milanti oktaruliza Milanti oktaruliza, Milanti Mokhamad Yusup Nur Khakim Munajat, Muhammad Fahrizal Munawar . Munawar Munawar Munawar Munawar Munira, Widia Musifa, Eva Nina Tanzerina Novilla Rezka Sjahjadi Oktafiani, Tiara oktaviani, muthia Rahmadania Rahmadania Rahmawati, Rahmawati Rahmi, Nelvin Ramadhan Tosepu Rifdah Nabila Riska Adillah Rivai, M Yunus Rizki . Rizqaini, Alfitratul Sabandia, La Salni Sarmayanta Sembiring Selviani, Ananda Seni Metasari Siregar, Wardah Khoiriah Sofa Farida Sofa Farida Sri Hidayati Sri Mulyani Suhadi Suhadi Suheyanto Suheryanto Sulaiman Zuhdi Sumarti Sumarti Supriyatna Supriyatna Supriyatna Supriyatna Surianto, Dewi Fatmawati Suryana, Nina Susanty, Sri Syafrina Lamin, Syafrina Syamsiah Wahyuni, Yayu Yolahumaroh, Yolahumaroh Yuanita Windusari Yuliana Arsil Yusmarita, Yusmarita Yusnita, Rini Yusup Nur Khakim, Mokhamad Zainuddin, Asnia Zara Yunizar Zefron, Zefron