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All Journal Journal of Food and Pharmaceutical Science Jurnal Penelitian Saintek Jurnal Ilmiah Farmasi EKSAKTA: Journal of Sciences and Data Analysis Statistika Indonesian Journal of Cancer Chemoprevention Program Kreativitas Mahasiswa - Penelitian Indonesian Journal of Biotechnology Majalah Obat Tradisional MPI (Media Pharmaceutica Indonesiana) INDONESIAN JOURNAL OF PHARMACY JURNAL BIOLOGI INDONESIA Molecular and Cellular Biomedical Sciences (MCBS) Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan JEPA (Jurnal Ekonomi Pertanian dan Agribisnis) Majalah Farmaseutik Indonesian Journal of Chemistry Media Ilmu Kesehatan JFIOnline INTEGRITAS : Jurnal Pengabdian Jurnal Farmasi Populer: Jurnal Penelitian Mahasiswa Jurnal Kedokteran Hewan Journal of Food and Pharmaceutical Sciences Agri Analytics Journal Indonesian Journal of Pharmacology and Therapy Jurnal Pengabdian Masyarakat Manage Journal of Pharmascience
Retno Murwanti
Departemen Farmakologi Dan Farmasi Klinik, Fakultas Farmasi, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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The Role of Lactiplantibacillus plantarum in Modulating the Gut-Skin Axis: A Comprehensive Review on Its Potential in Managing Atopic Dermatitis Cahyo Nurani, Sekar; Novrizal Abdi Sahid , Muhammad; Murwanti, Retno
Journal of Food and Pharmaceutical Sciences Vol 13, No 3 (2025): J.Food.Pharm.Sci
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.20639

Abstract

Atopic Dermatitis (AD) is a chronic inflammatory skin condition marked by impaired skin barrier function, immune system irregularities, and microbial imbalance. This research examines the efficacy of Lactiplantibacillus plantarum, a probiotic recognized for its established safety and advantageous characteristics, in the management of atopic dermatitis (AD). The pathophysiology of AD encompasses genetic, environmental, and immunological components, with dysbiosis of skin and gut microbiota being essential. L. plantarum has shown beneficial effects in controlling gut and skin microbiota, improving skin barrier integrity, and modulating immunological responses via processes including short-chain fatty acid (SCFA) synthesis, cytokine regulation, and competitive exclusion of pathogens. Clinical investigations demonstrate that L. plantarum supplementation can diminish the severity of atopic dermatitis, as assessed by the SCORAD index, and enhance skin barrier integrity. The effectiveness of probiotic therapy may be affected by genetic, nutritional, and environmental variables. This review emphasizes the promise of L. plantarum as a therapeutic agent for AD, while also discussing the limitations and future possibilities for probiotic-based therapies in managing this intricate condition.
Evaluation of synthetic‐gene recombinant LipL32 antigen for IgM ELISA detection of Leptospira infection Widiastuti, Dyah; Paramita, Dewi Kartikawati; Murwanti, Retno; Kusrini, Ina; Wijayanti, Nastiti; Haryanto, Aris
Indonesian Journal of Biotechnology Vol 30, No 4 (2025)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijbiotech.111102

Abstract

Leptospirosis presents with nonspecific clinical features and requires time‐consuming laboratory tests for gold standard diagnosis. This study aims to design and characterize the recombinant LipL32 from synthetic gene and assess its performance as an antigen for detecting leptospirosis. The antigen was developed by cloning the LipL32 gene conserved portion of Leptospira interrogans serovar Icterohaemorrhagiae strain Langkawi. The immunoinformatic was used to characterize the developed rLipL32. Western blot results using anti‐histidine revealed a band of rLipL32 protein at ~40 kDa. Subsequently, it was used to examine the IgM antibody on human sera by using ELISA. The IgM‐LipL32 ELISA was evaluated using 67‐positive and 25‐negative sera and compared with a commercial ELISA. With a cut‐off value of 0.8, it showed 85.7% sensitivity, 83.3% specificity, a 48% positive prediction value (PPV), and 97% negative prediction value (NPV), indicating modest performance compared to existing commercial kits. The rLipL32 is a potential antigen for detecting IgM using ELISA; however, for use in low incidence areas, a confirmation test is crucial.
KAJIAN PROYEKSI PRODUKSI dan DAYA SAING KOMODITAS PERKEBUNAN dan PERTANIAN KABUPATEN JEMBER dalam MENDUKUNG POTENSI EKSPOR Murwanti, Retno; Nurul Fathiyah F
Jurnal Ekonomi Pertanian dan Agribisnis Vol. 9 No. 4 (2025)
Publisher : Department of Agricultural Social Economics, Faculty of Agriculture, Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

The growth of the agricultural and plantation sectors in Jember Regency plays an important role in the local economy, particularly in providing commodities with high export potential. Along with the development of global market demand, managing production, stock availability and increasing the competitiveness of commodities are key to strengthening Jember's position in the international market. Maintaining productivity and improving the competitiveness of export products requires in-depth projection analysis. This research aims to project the production and stocks of plantation and agricultural commodities in Jember Regency for the period 2024-2026, and to map their competitiveness and export potential. The problem of this research is to project the production and stocks of plantation and agricultural commodities in Jember Regency in 2024-2026, and to map the competitiveness and export potential of these commodities. The method used in this research is quantitative descriptive method with production projection approach using trend analysis and competitiveness calculation using Revealed Comparative Advantage (RCA). Data were obtained from relevant agencies and official publications and then analysed to describe the production potential and comparative advantage of the main commodities of Jember Regency. The results show that several plantation and agricultural commodities have stable projected production increases over the period 2024-2026. Certain commodities such as tobacco, coffee and cocoa show high competitiveness and significant export potential based on RCA values. These results suggest that sustainable production management and competitiveness improvement strategies are needed to maximise export potential. The results of this study are expected to serve as a basis for local government and stakeholders in designing export development policies for Jember's leading commodities in the international market.
Bibliometric Analysis of Medicinal Plants Research for Diabetes Mellitus in Indonesia Khoerul Anwar; Nanang Fakhrudin; Retno Murwanti; Agung Endro Nugroho
Journal of Pharmascience Vol. 12 No. 2 (2025): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v12i2.23703

Abstract

Diabetes mellitus (DM) memiliki hubungan yang erat dengan perubahan pola makan dan gaya hidup yang tidak sehat. Jumlah penderita diabetes di Indonesia terus meningkat. Minat masyarakat dalam mengonsumsi tanaman obat semakin berkembang karena pasien lebih memilih produk alami yang dianggap lebih aman. Penelitian tentang tanaman obat sebagai agen antidiabetes juga menunjukkan tren yang meningkat. Studi ini bertujuan untuk memetakan penelitian yang menggunakan tanaman obat terkait diabetes di Indonesia. Data subjek penelitian diperoleh dari Scopus, dan perangkat lunak statistik RStudio dengan paket bibliometric digunakan untuk menganalisis dan memvisualisasikan data. Hasil analisis menunjukkan bahwa pertumbuhan publikasi di bidang ini mencapai 36,25% per tahun. Jumlah penulis bersama per dokumen adalah 4,93 dengan tingkat kolaborasi internasional sebesar 15,12%. Sebanyak 1.548 artikel dengan 4.877 penulis diterbitkan di 429 jurnal dan prosiding terpilih. Elya B (n = 35), Universitas Airlangga (n = 435), dan IOP Conference Series: Earth and Environmental Science (n = 92) merupakan penulis, afiliasi, dan penerbit paling produktif. Dengan jumlah sitasi per artikel sebesar 7,78 menunjukkan bahwa penelitian dari Indonesia berkontribusi pada penelitian lain. Penulis artikel di Indonesia sebagian besar (89,73%) berkolaborasi dengan peneliti sesama di Indonesia, sementara sisanya (10,27%) berkolaborasi dengan peneliti di luar negeri seperti Jepang, Malaysia, Thailand, China, dan Korea. Dapat disimpulkan bahwa kuantitas dan kualitas penelitian tentang tanaman obat untuk DM di Indonesia semakin meningkat dan berkontribusi pada penelitian lebih lanjut untuk pengelolaan diabetes. Kata Kunci: Bibliometric, Diabetes Mellitus, Tumbuhan Obat, Scopus, Rstudio Diabetes mellitus (DM) strongly associated with changes in unhealthy diet and lifestyles. The number of diabetic patients in Indonesia continues to increase. Public interest in consuming medicinal plants was developing because patients prefer on natural products and are considered safer. Research on medicinal plants as antidiabetic agents also shows an increasing trend. This study aims to map research using medicinal plants related to diabetes in Indonesia. Data on research subjects were retrieved from Scopus and the bibliometric package in RStudio statistical software was used to analyze and visualize the data. The results of the analysis showed that the growth of publications in this field was 36.25% per year. The number of co-authors per document was 4.93 with an international co-authorship rate of 15.12%. A total of 1548 articles with 4877 authors were published in 429 selected journals and proceedings. Elya B (n = 35), Universitas Airlangga (n = 435), the IOP Conference Series: Earth and Environmental Science (n = 92) was the most productive author, affiliation, and publisher. With the number of citations per article of 7.78, it shows that this research from Indonesia contributes to another research. The authors of the articles in Indonesia mostly (89.73%) collaborated with fellow researchers in Indonesia, while the rest (10.27%) collaborated with researchers abroad such as Japan, Malaysia, Thailand, China, and Korea. It can be concluded that the quantity and quality of research on medicinal plants for DM in Indonesia is increasing and contributing to further research for diabetes management.
Mentoring SCA Berbasis Web Madinapay Pada AUMDik Se-Kab. Banyuwangi Diyah Probowulan; Retno Murwanti
Jurnal Pengabdian Masyarakat Manage Vol. 5 No. 2 (2024): Agustus
Publisher : Universitas Muhammadiyah Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32528/manage.v5i2.1767

Abstract

Muhammadiyah is a da'wah organization that devotes itself to teaching life based on tawhid and renewal, amar ma'ruf nahi mungkar. Muhammadiyah's education reform aims to unify religion and values and advance the education system. The Council of Education is working hard to improve Amal Usaha Muhammadiyah's (AUM) management in education, especially in the financial management of elementary, junior high, and high school. AUM financial management has improved, but not optimally because AUMDik in Banyuwangi Regency still has not operationalized its financial reporting through the Madinapay website. The results of the current situation analysis of LPPK East Java are (1) LPPK has made efforts to realize effective, efficient and accountable financial governance by creating a budget plan program for Muhammadiyah East Java schools and making financial reporting applications; (2) LPPK has not completed the application with manual guidance; (3) LPPK has carried out system socialization to Muhammadiyah Schools, but the results are not optimal because Muhammadiyah schools in East Java do not use the application until now. The results of service activities at AUMDik in Banyuwangi Regency, especially school treasurers, 1) partners have increased their ability to operate the Madinapay website, 2) some partners already have an integrated financial system but have not been integrated with stakeholders.
Co-Authors Abdul Rohman Adam Hermawan Agung Endro Nugroho Agung Endro Nugroho Ahmad Marzuki Alexxander, . Alexxander, . Amalia, Latifa Anami Riastri Andayana Puspitasari Gani Andayana Puspitasari Gani Andayana Puspitasari Gani Annisa, Siti Nur Anselma Ivanawati Arief Nurrochmad Arief Nurrochmad Arief Nurrochmad Arief Nurrochmad Arief Rahman Hakim Arifka, Vigha Ilmanafi Aris Haryanto Ariska Deffy Anggarany, Ariska Deffy Ashfannada, Nuqya Asri Mega Putri Azizah Amin Azmi Rahmadani Bambang Sulistiyo Ari Sudarmanto Bani Adlina Shabrina Bayu Irawan, Muhamad Bayu Prio Septiantoro Beni Lestari Budastra, Wayan Cintya Ganes Cahyo Nurani, Sekar Cindy Puspita Sari Devina Martina Devita Anggraeni Devita Anggraeni Devyanto Hadi Triutomo Dewi Kartikawati Paramita Dhania Novitasari Dhirgo Adji Dhirgo Adji Diana Rachma Ningsih Dwi Brilyani Sandy Dwi Salim, Rozin Dyah Afritasari Dyah Aryani Perwitasari Dyah Widiastuti Dyaningtyas Dewi Pamungkas Putri Edy Meiyanto Edy Meiyanto Edy Meiyanto Edy Meiyanto Edy Meiyanto Edy Meiyanto Effendi, Adha Maula Erna Prawita Setyowati Erna Prawita Setyowati Fikriansyah Fikriansyah Fita Rahmawati Fitri, Dafina Aisya Fitriana Hayyu Arifah Gagas Pradani Nur Ilmawati Gani, Andayana Puspitasari Ginna Zabrina Hayati, Farida Hendri Wasito Herwandhani Putri Hidayah, Alifia Brilliani Hilyatul Fadliyah I Gusti Ngurah Agung Dewantara Putra Ida Ayu Putu Sri Widnyani Idlohatud Dilalah Ika Puspita Sari Illian, Didi Nurhadi Imono Argo Donatus, Imono Argo Ina Kusrini Iren Wati Siahaan Jenie, Riris Istighfari Juang Juansa Khafi, Muhammad Khasanah, Aisyah Nur Khoerul Anwar Khoerul Anwar Kustanto, Satya Prima Layung Sekar Sih Wikanthi Ledi, Ledi Klarismawati Lodyta Nawang Tika lubis, muhammad fauzan Lukman Hakim Luthfiyyah, Annisa Tiara Martien , Ronny Mentari Widiastuti Miftahus Sa'adah Mustofa Mustofa Naisbitt Iman Hanif, Naisbitt Iman Nanang Fakhrudin Nanang Fakhrudin, Nanang Nanda Saifullah Sulaiman, Teuku Nastiti Wijayanti Ngurah Agung Dewantara Putra, I Gusti Nindi Wulandari Nindya Budiana Putri Nindya Budiana Putri Ningsih, Diana Rachma Norita Citra Yuliarti, Norita Citra Novrizal Abdi Sahid , Muhammad Nursani, Rabila Nurul Fathiyah F Nurul Mukhlisa Pratiwi, Rima Dwi Prawitasari, Saptya Prisnu Tirtanirmala Probowulan, Diyah Purnomo, Kurnia Rahayu Purwantiningsih Purwantiningsih Rahmawaty Rachmady Rahmayani, Almira Retno S. Sudibyo Retno Sunarminingsih Sudibyo Riandari , Teti Mariam Rima Munawaroh Risa Umari Yuli Aliviyanti Ritmaleni, Ritmaleni Rizkita, Anggraini Ihza Rohmad Yudi Utomo Rohman, Abdul Rommy Sagala, Reynelda Juliani Sardjiman . Sari Haryanti Sari Haryanti Sari, Laras Ratna Shofa Annur Siswadi Siswadi Sri Susilowati Sri Tasminatun Sri Wahdaningsih Subagus Wahyuono Sudarsono Sudarsono Sugeng Riyanto Sugiyanto . Sugiyanto . Sulaiman, T.N Saifullah Sumaiyah, Sumaiyah Susi Ari Kristina Suwijiyo Pramono Suwijiyo Pramono Tamhid, Hady Anshory Tampubolon, Keshia Thoriq Ziyad, Thoriq Tiffany, Ghea Rachella Triana Candraningrum Triana Hertiani Triawan Adi Cahyanto Ulfa Afrinurfadhilah Darojati Wahyu Utaminingrum Widya Leontin Susanti Yoce Aprianto Yosi Bayu Murti Yundari, Yundari Zahrotul Ulum Ziana Walidah, Ziana