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All Journal Pendas : Jurnah Ilmiah Pendidikan Dasar Specta Journal of Technology Dirasah : Jurnal Studi Ilmu dan Manajemen Pendidikan Islam Journal of Stem Cell Research and Tissue Engineering Jurnal Rekayasa Lingkungan JOURNAL SCIENTIFIC OF MANDALIKA (JSM) Action Research Literate (ARL) Jurnal Dunia Pendidikan Journal of Community Service JKMP (Jurnal Kebijakan dan Manajemen Publik) International Journal of Community Service (IJCS) Journal of Research and Publication Innovation MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation Instink: Inovasi Pendidikan, Teknologi Informasi dan Komputer Lentera Jurnal Pengabdian Bangsa Prosiding Seminar Nasional dan Call For Paper Kebidanan Universitas Ngudi Waluyo Ta'dibiya: Jurnal Agama dan Pendidikan Islam Blockchain Frontier Technology (BFRONT) International Journal of Community Services Tadibiya; Jurnal Agama dan Pendidikan Islam SISFOTENIKA Jurnal Pengabdian Masyarakat Mandira Cendikia (JPKM-MC) JIS: Journal ISLAMIC STUDIES Sultan Adam : Jurnal Hukum dan Sosial SCIENTIA JOURNAL : Jurnal Ilmiah Mahasiswa Lubna: Journal of Islamic Elementary Education Jurnal Inovasi Administrasi Negara Terapan Jurnal Kesehatan Ibnu Sina (j-kis)
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Circular Economy Development Policy in Magetan Regency: Case Study of the Leather Industry and its Impact on Improving the Community's Economy: Kebijakan Pengembangan Ekonomi Sirkuler di Kabupaten Magetan: Studi Kasus Industri Kulit dan Dampaknya terhadap Peningkatan Ekonomi Masyarakat Sukarsono, Faza Muhammad; Gamaputra, Gading; Winata, Muhammad Danu; Kurniawan, Badrudin; Noviyanti; Lestari, Yuni; Wibisono, Haryo Kunto
JKMP (Jurnal Kebijakan dan Manajemen Publik) Vol 13 No 1 (2025): April
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/jkmp.v13i1.1818

Abstract

This study aims to analyze the circular economy development policy in Magetan Regency, focusing on the leather industry and its impact on improving the community's economy, especially on Jalan Sawo, Selosari Village. The method used is a qualitative approach, which includes in-depth interviews with industry players, direct observation at the location, and analysis of documents related to the policy. The results of the study indicate that the implementation of the circular economy policy not only increases community income through the creation of new jobs but also contributes to waste reduction and increased environmental awareness among the community. In addition, this study identifies challenges faced in implementing the policy, such as lack of training and technical support. Recommendations are provided to improve the effectiveness of this policy, including the need for collaboration between the government, private sector, and the community in creating a sustainable circular economy ecosystem. This research is expected to contribute to the development of better policies in the future.
FUNCTIONAL ROLE OF VIMENTIN'S CYSTEINE IN XIST-MEDIATED EMT INHIBITION IN BREAST CANCER Jayanti; Melisa; Arnando; Mur'ah; Noviyanti
Journal of Stem Cell Research and Tissue Engineering Vol. 9 No. 1 (2025): JOURNAL OF STEM CELL RESEARCH AND TISSUE ENGINEERING
Publisher : Stem Cell Research and Development Center, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jscrte.v9i1.73554

Abstract

Breast cancer is the most commonly diagnosed malignancy among women worldwide and a leading cause of cancer-related mortality, primarily due to its high metastatic potential. One mechanism underlying metastasis is the epithelial-to-mesenchymal transition (EMT), which enhances cancer cell mobility, invasiveness, and resistance to treatment. Vimentin, a type III intermediate filament protein, is a hallmark of EMT and plays a structural and regulatory role in cytoskeletal organization and cellular stress responses. Recent studies have highlighted the importance of a single cysteine residue at position 328 (C328) in vimentin, which functions as a redox-sensitive site influencing filament dynamics. However, the role of C328 in cancer progression remained largely unexplored. This literature review investigates the effect of a single amino acid substitution—C328 to serine (C328S)—on breast cancer cell behavior, focusing on findings published between 2020 and 2025, sourced from PubMed and Google Scholar. Evidence from MCF-7 breast cancer cell models reveals that expression of C328S-VIM induces morphological changes, cytoskeletal disorganization, and increased proliferation, migration, and invasion. Notably, C328S-VIM upregulates the long non-coding RNA XIST, which promotes EMT, estrogen independence, and stem-like properties. These findings indicate that the native C328 residue serves a tumor-suppressive function, partly through modulation of XIST activity. Overall, this review presents a novel insight into how a single amino acid mutation in vimentin can reprogram breast cancer cells toward a more aggressive and stem-like phenotype. The study highlights C328 as a potential therapeutic target and broadens our understanding of the molecular mechanisms driving breast cancer progression.
Penerapan Akupresure untuk Mengurangi Nyeri Haid pada Remaja Putri Eva Tresanita Damanik; Yekti Murbarani; Florida; Noviyanti; Syalmah; Melgita Sari Nurjayanti Saputri; Ari Widyaningsih
Prosiding Seminar Nasional dan CFP Kebidanan Universitas Ngudi Waluyo Vol. 4 No. 1 (2025): Prosiding Seminar Nasional dan Call for Paper Kebidanan Universitas Ngudi Waluy
Publisher : Universitas Ngudi Waluyo

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Abstract

Dysmenorrhea is pain that occurs during menstruation and can be very disruptive to daily activities. Menstrual pain is a common complaint experienced by many women and is a symptom, Adolescence is a problem of transition from puberty to adulthood or the process of growing towards mental, emotional, social and physical maturity. During adolescence, physical changes occur accompanied by changes in the reproductive organs. Dysmenorrhea in some adolescents is a torture in itself that must be experienced every month. In general, the treatment of dysmenorrhea pain is divided into two categories, namely pharmacological and non-pharmacological. One of the midwifery care that can be given to reduce menstrual pain or dysmenorrhea is acupressure. Acupressure is a massage or pressure on the meridian points of the body. The problem of menstrual pain or dysmenorrhea still occurs in many adolescent girls at the Tanjung Palas but there is no treatment to overcome it. In fact, menstrual pain or dysmenorrhea can affect the daily activities of adolescent girls including difficulty concentrating, emotional conflict, tension, anxiety, and disrupting the learning process, feeling uncomfortable, decreased activity in the learning process. Based on the problems that arise, community service activities are needed to overcome this. The activity began with an opening and pre-test, secondly the delivery of material about Acupressure to reduce menstrual pain in adolescent girls as well as the practice of doing acupressure to reduce menstrual pain, thirdly the closing and post-test which was attended by 16 adolescent girls. From these activities, it was found that there was an increase in the knowledge of adolescent girls about acupressure to reduce menstrual pain in adolescent girls.   Abstrak Dismenore adalah rasa nyeri yang terjadi saat menstruasi dan bisa sangat mengganggu aktivitas sehari-hari. Nyeri haid ini merupakan keluhan umum yang dialami oleh banyak perempuan dan merupakan gejala, Masa remaja merupakan masalah peralihan dari pubertas ke dewasa atau proses tumbuh kearah kematangan mental, emosional,sosial dan fisik. Pada masa remaja terjadi perubahan fisik yang disertai dengan perubahan organ reproduksi. Dismenore pada sebagian kaum remaja merupakan siksaan tersendiri yang harus dialami setiap bulannya. Secara umum penanganan nyeri dismenore terbagi dalam dua kategori yaitu farmakologis dan non farmakologis. Salah satu asuhan kebidanan yang dapat diberikan untuk mengurangi nyeri haid atau dismenore adalah akupresure. Akupresure adalah pemijatan atau penekanan pada titik-titik meridian tubuh. Permasalahan nyeri haid atau dismenore ini masih banyak terjadi pada remaja putri di Tanjung Palas namun belum ada penanganan untuk mengatasinya. Padahal, nyeri haid atau dismenore dapat mempengaruhi aktivitas sehari-hari remaja putri diantaranya sulit berkonsentrasi, konflik emosional, ketegangan, kecemasan, dan mengganggu proses belajar, merasa kurang nyaman, penurunan keaktifan dalam proses pembelajaran. Berdasarkan masalah yang muncul, maka diperlukanlah kegiatan pengabdian masyarakat untuk mengatasi hal tersebut. Kegiatan diawali dengan pembukaaan dan pree test , kedua penyampaian materi tentang Akupresure untuk mengurangi nyeri haid pada remaja putri sekaligus praktik melakukan akupresure untuk mengurangi nyeri haid, ketiga penutup dan post tes yang di hadiri oleh 16 remaja putri. Dari kegiatan tersebut didapatkan ada peningkatan pengetahuan remaja putri tentang akupresure untuk mengurangi nyeri haid pada remaja putri.
PENERAPAN SISTEM INFORMASI MANAJEMEN DALAM MANAJEMEN BERBASIS SEKOLAH (STUDI KASUS PADA SISTEM INFORMASI AKADEMIK STIT AL-IHSAN BALEENDAH) Noviyanti; Amalia, Rosemila; Mustika, Sri; Salinan; Warta, Waska
Pendas : Jurnal Ilmiah Pendidikan Dasar Vol. 10 No. 03 (2025): Volume 10 No. 03 September 2025
Publisher : Program Studi Pendidikan Guru Sekolah Dasar FKIP Universitas Pasundan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23969/jp.v10i03.30414

Abstract

The rapid development of information and communication technology has significantly impacted the education sector, particularly in improving the effectiveness, efficiency, and accountability of school management. This study aims to analyze the implementation of a Management Information System (MIS) to support School-Based Management (SBM) at STIT Al-Ihsan Baleendah. Using a descriptive qualitative case study approach, the research explores planning, organizing, implementation, and evaluation of MIS in the institution. Data were collected through interviews, observations, and document analysis, then analyzed interactively. The findings show that MIS has accelerated academic administrative services, improved data accuracy, and facilitated data-driven decision-making. However, challenges remain, including limited infrastructure, insufficient digital literacy among staff, and lack of formal documentation. Regular evaluation and continuous improvement efforts are crucial for sustainable system performance. This study contributes to both theory and practice by providing insights into the integration of MIS and SBM in Islamic higher education contexts. Keywords: Management Information System, School-Based Management, Higher Education, Academic Administration, Digital Literacy;
Antioxidant Activity Test Of Red Spinach Leaf (Amaranthus Tricolor L.) Extract And Fraction With Methode (2,2-Diphenyl-1 Picrylhydrazyl) Noviyanti; Asterina, Yolanda; Khairunnisa, Anita
SPECTA Journal of Technology Vol. 9 No. 2 (2025): Specta Journal of Technology
Publisher : LPPM ITK

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35718/specta.v9i2.8481340

Abstract

Abstract Red spinach (Amaranthus tricolor L.) is a leafy vegetable known for its high antioxidant potential due to its bioactive compounds. This study aimed to evaluate the antioxidant activity of extracts and fractions of red spinach leaves using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. Extraction was conducted through cold maceration with ethanol 96%, followed by fractionation using solvents of varying polarity: n-hexane, ethyl acetate, and water. Phytochemical screening revealed the presence of alkaloids, flavonoids, quinones, saponins, steroids, and tannins, which contribute to the plant's antioxidant properties. The antioxidant activity of the ethanol extract and fractions was assessed based on their IC50 values. The ethanol extract demonstrated moderate antioxidant activity with an IC50 of 122.09 µg/mL, while the n-hexane and water fractions showed similar moderate activity with IC50 values of 117.33 µg/mL and 124.36 µg/mL, respectively. The ethyl acetate fraction exhibited strong antioxidant activity with an IC50 value of 64.77 µg/mL, attributed to the presence of semi-polar compounds such as flavonols. The results confirmed the significant free radical scavenging potential of red spinach, particularly in its ethyl acetate fraction. This study highlights the potential of red spinach leaves as a natural source of antioxidants with applications in the pharmaceutical, health, and food industries. Keywords: Red spinach, Amaranthus tricolor L., DPPH, antioxidant activity, IC50.
IDEALITAS DAN REALITAS KEMAMPUAN GURU MI/SD DALAM MENGIMPLEMENTASIKAN PEMBELAJARAN TEMATIK Nurkhairina; Hidayatullah, Agus; Rosyidah, Neneng Aida; Noviyanti
Ta'dibiya Vol 3 No 1 (2023): Ta'dibiya: Jurnal Agama dan Pendidikan Islam
Publisher : Staisman Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61624/japi.v3i1.23

Abstract

Learning in the 2013 curriculum uses integrated thematic learning. This causes teachers to master and carry out thematic learning well. However, there are many problems that occur, then what is the ideal of the teacher in carrying out thematic learning. This research intends to know and explain in detail about the ideals and reality of MI/SD teachers' abilities in implementing thematic learning. The results of this study are; Ideally the teacher in this thematic learning is to provide meaningful teaching and experiences to students. Not only that, a teacher in addition to being a professional educator, is also an educator, teacher, mentor, director, assessor, and evaluator of students, especially in early childhood education and basic education. There are two factors that impact on the obstacles for teachers to implement, namely: internal factors and external factors. Teachers are still lacking in comprehensive education and training; teachers also still find it difficult to integrate tactics in the learning theme.
IDEALITAS DAN REALITAS KEMAMPUAN GURU MI/SD DALAM MENGIMPLEMENTASIKAN PEMBELAJARAN TEMATIK Nurkhairina; Hidayatullah, Agus; Rosyidah, Neneng Aida; Noviyanti
Ta'dibiya Vol 3 No 1 (2023): Ta'dibiya: Jurnal Agama dan Pendidikan Islam
Publisher : Staisman Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61624/japi.v3i1.23

Abstract

Learning in the 2013 curriculum uses integrated thematic learning. This causes teachers to master and carry out thematic learning well. However, there are many problems that occur, then what is the ideal of the teacher in carrying out thematic learning. This research intends to know and explain in detail about the ideals and reality of MI/SD teachers' abilities in implementing thematic learning. The results of this study are; Ideally the teacher in this thematic learning is to provide meaningful teaching and experiences to students. Not only that, a teacher in addition to being a professional educator, is also an educator, teacher, mentor, director, assessor, and evaluator of students, especially in early childhood education and basic education. There are two factors that impact on the obstacles for teachers to implement, namely: internal factors and external factors. Teachers are still lacking in comprehensive education and training; teachers also still find it difficult to integrate tactics in the learning theme.
Analisis Indeks Kepuasaan Masyarakat Pada Layanan Kepengurusan Surat Keterangan Tanda Lapor Kehilangan (SKTLK) di Polsek Jambangan Kusuma Dewi, Novian; Noviyanti
Jurnal Inovasi Administrasi Negara Terapan (Inovant) Vol. 1 No. 1 (2023): Kebijakan dan Tatakelola Lembaga Publik untuk Tujuan Pembangunan Berkelanjutan
Publisher : Universitas Negeri Surabaya

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Abstract

The problems that exist in the service of managing the Certificate of Loss Report (SKTLK), Polsek Jambangan has not implemented the IKM, lack of human resources which results in less than optimal service, lack of publication related to information about the service of managing the Certificate of Loss Report (SKTLK) and lack of infrastructure. Therefore, the purpose of this study is to describe and analyze the results of the Community Satisfaction Index (SMI) on the service of managing the Certificate of Loss Report (SKTLK) at the Jambangan Police. This research uses a quantitative approach with a survey method. In this study to measure public satisfaction with the services provided by Jambangan Police is to use the Community Satisfaction Index in accordance with the Regulation of the Minister of Administrative Reform of Bureaucratic Reform (Permenpan RB) Number 14 of 2017 concerning Guidelines for Preparing Community Satisfaction Surveys for Public Service Delivery Units. The sampling technique used Accidental Sampling with a population of 250 people and a sample size of 71 people using data collection techniques in the form of questionnaires. The results showed that the Community Satisfaction Index at Jambangan Police fell into the "GOOD" category with an interval value of 81.57. Suggestions given to Jambangan Police in improving elements that have not fully run smoothly.
Analisis Indeks Kepuasan Masyarakat Pada Layanan Sirkulasi Perpustakaan di Kementerian Desa, Pembangunan Daerah Tertinggal dan Transmigrasi Matulessy, Stella Maria; Noviyanti
Jurnal Inovasi Administrasi Negara Terapan (Inovant) Vol. 1 No. 1 (2023): Kebijakan dan Tatakelola Lembaga Publik untuk Tujuan Pembangunan Berkelanjutan
Publisher : Universitas Negeri Surabaya

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Abstract

Library circulation services are essential to carry out a satisfaction survey to determine the level of satisfaction from the community's point of view to improve and develop services in the future. The problems found in the library circulation service of the Ministry of Villages, Development of Disadvantaged Regions, and Transmigration (Kemendesa PDTT) are that they have not implemented the Community Satisfaction Index (IKM), the system has not been computerized, the lack of utilization of complaints, suggestions, and input. Therefore, the purpose of this study is to describe and analyze the results of the Community Satisfaction Index on library circulation services at Kemendesa PDTT. The type of research used is quantitative with a descriptive method using Community Satisfaction Index measurements by the Regulation of the Minister of Administrative Reform and Bureaucratic Reform Number 14 of 2017 concernin guidelines for Compiling Public Satisfaction Surveys in Public Service Delivery Units. Sampling technique using Accidental Sampling with a total sample of 73 respondent. Data collection techniques include questionnaires, interviews, observation, and documentation. Data analysis techniques use tabulation, data verification, IKM analysis, and conclusion. The results showed that the Community Satisfaction Index in the Kemendesa PDTT library was included in the "GOOD" category with a value of 81.82. The element that has the highest score is cost/tariff which is worth 100.00 and the element that has the lowest score is complaint, suggestion, and input which is worth 77.05.
Efektivitas Pelayanan Kesehatan Melalui Electronic Government (Studi Kasus Pada Elektronik Sistem Kesehatan Lamongan "eSikla" di Puskesmas Deket Kecamatan Deket Kabupaten Lamongan) Takharus Awal, Annisa Zahra; Noviyanti
Jurnal Inovasi Administrasi Negara Terapan (Inovant) Vol. 1 No. 1 (2023): Kebijakan dan Tatakelola Lembaga Publik untuk Tujuan Pembangunan Berkelanjutan
Publisher : Universitas Negeri Surabaya

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Abstract

The purpose of this research is to analyze, and describe the effectiveness of health services through Electronic Health Lamongan (eSikla) at Puskesmas Deket. Electronic Health System Lamongan (eSikla) is a health information system developed to assist officers at each health center in Lamongan Regency, including the Deket Health Center, Deket District, Lamongan Regency. Data collection techniques used in this research include: interviews, observations, and documentation with purposive sampling technique where the research subjects in this study consisted of: eSikla program managers at the Lamongan Regency Health Office, Deket Puskesmas officers and Deket Puskesmas visitors. The data sources used are primary and secondary data sources with data analysis techniques including: data reduction, data presentation and conclusion drawing. This type of research is descriptive qualitative research with five indicators of effectiveness from Siagian as a theoretical basis, while the five indicators include: Human resources (HR), Funds, Facilities and infrastructure, Quantity and Quality and also Time. The results of the research show that health services through the Electronic Health System Lamongan "eSikla" at Puskesmas Deket Deket District, Lamongan Regency are still not effective. It is because of the five indicators put forward by Siagian, four of them are still not effective with the following description: Human resource indicators are less effective because not all officers can operate eSikla via computer. Fund indicators are also less effective due to the lack of funds or budget for updating or improving the quality of eSikla applications and server maintenance, facilities and infrastructure can be said to be effective because they are in accordance with the provisions of the Lamongan District Health Office, quality and quantity are also less effective because there are several obstacles related to the quality of the eSikla application, and time indicator is also not effective because implementation is often delayed.
Co-Authors Agus Prasetyawan Ainy, Afra Nur Alfira S Amalia , Rosemila Amalia, Rosemila AMBAR WIDYA LESTARI Andriani Angga Domeos Manggara Antonio Constantino Soares Ari Lutfia Sari Ari Widyaningsih Arianti, Gisela Arnando Asma, Nurul ASNI Asterina, Yolanda Aulia Rosida, Nabila Azizah, Maulia Salsanabila Azwar, Yessi Badrudin Kurniawan Basuki Batubara, Hamidah Sari Bella, Ivvon Septina Berliani, Dedek Bunga Tiara Carolin DIAN ARLUPI UTAMI Dirgayusa Febrianaga, Pipit Eliyah Emy Susanti EVA AULIA MUKTI Eva Tresanita Damanik Faisal R Dongoran, Faisal R Fitrianingrum, Aditya Pratiwi Florida Gading Gamaputra Handayani, Sri Hidayatullah, Agus Hikmah, S.E., M.Si. Hutasoit, Eva Santi Ice Irawati Imanudin Siregar Indera Hayati, Aulia Dian Isnaini Fitri Effendi Jayanti Juliani, Wahyuni Karimah, Arzetya Fitri Al Keristanti, Ruri Khaatamal Awlad Khairunnisa, Anita Khummad Robby, Tasbikhy Kusuma Dewi, Novian Leni Utami Lina Haryani Lukmawati, Luthfi Rizky Mar'atus Sholikhah Matulessy, Stella Maria Mauizatul Hasanah Maulida Mega Dewi Lestari Melgita Sari Nurjayanti Saputri Melisa Misriningsih, Dwi Cahyani Mohammad Yogi Hamdi Muhammad Zaini Mur'ah Murni Murniati Nanik Cahyati Natasha, Ayu Naufal Hanif Ramadhan Norwanda Nur Ichani Nur Rachma, Dita Laela Nurkhairina Nurlina Nurmayana Oskar Pardosi, Renhad Andreas Permana, Handy Januar Pinata, Putri Prasetyo Isbandono Punarbawa, Gede Putri Fatahillah, Ratu Egalitarian Putri Nabilah Ranti Widayanti Ratna Sari, Monika Retno Widuri, Aliffionia Sindy Hendrati Rice Haryati Rinanti, Maghalita Rinanti Rita Dewi Triastianti Rizka Hadya Robby Cokro Buwono Rosyidah, Neneng Aida Salinan Sarasati, Inda Siti Maesaroh Sophia Sri Mustika Sujarwo Putri, Tarisa Sukarsono, Faza Muhammad Suwandari, Lilis Suwiase, Putu Syalmah Tahlia Wahyuning Tias Takharus Awal, Annisa Zahra Tanosida K Theresa Heidi A Kanadjara Wahyuni, Rika Sri Warsiyah Warta, Waska Wati, Norlidia WENI ROSDIANA Wibisono, Haryo Kunto Widyaningsih, Triatmi Sri Widyaningtyas, Dwi Wilujeng, Vianti Winata, Muhammad Danu Yekti Murbarani Yeni Rosyeni Yulistia Yuni Lestari Yuni Lestari Yusuf, Salsabila Zalikha Zulfahmi