Claim Missing Document
Check
Articles

Down Syndrome : Through The Eyes of The Parents Ziske Maritska; Fakhri Abdurrahman; Bintang Arroyantri Prananjaya; Nita Parisa; Syifa; Triwani
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 5 No. 3 (2018): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universi
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v5i3.106

Abstract

Sindroma Down merupakan salah satu kejadian kelainan kromosom tipe aneuploidi yang kerap ditemukan. Kejadian Sindroma Down terkait erat dengan disabilitas intelektual dan stugma sosial yang melekat padanya. Pandangan orang tua mengenai Sindroma Down yang tercerminkan melalui perilaku amat penting karena dukungan keluarga merupakan salah satu kunci utama untuk mengoptimalkan kualitas hidup penyandang Sindroma Down. Studi ini merupakan studi deskriptif pada orang tua penyandang Sindroma Down yang bersekolah di Sekolah Luar Biasa (SLB) di Palembang. Perilaku orang tua diukur dengan menggunakan kuesioner HealthStyles©. Sebagian besar orang tua penyandang Sindroma Down sepakat bahwa anak dengan Sindroma Down harus bersekolah di SLB (82,5%) karena mayoritas meyakini pencampuran penyandang Sindroma Down di sekolah biasa dapat mengganggu murid lain (60%). Namun orang tua memiliki pandangan optimis bahwa anak penyandang Sindroma Down dapat bekerja jika telah dewasa (72,5%). Mereka pun percaya bahwa penyandang Sindroma Down tidak lebih rentan mengalami kecelakaan kerja di tempat kerja (37,5%). Dari studi ini terlihat bahwa orang tua penyandang Sindroma Down memiliki perilaku yang bervariasi tergantung dari aspek mana mereka memandang Sindroma Down.
Optimalisasi Pengetahuan Tokoh Masyarakat Mengenai Penyakit Asam Urat Melalui Sosialisasi Kesehatan Evi Lusiana; Nia Savitri Tamzil; Nita Parisa; Desi Oktariana; Gita Dwi Prasasty; Indri Seta Septadina
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 9 No. 1 (2022): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universi
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v9i1.209

Abstract

Penyakit asam urat merupakan dalah satu penyakit yang banyak diderita masyarakat yang ditandai dengan rasa nyeri pada persendian yang disebabkan endapan kristal monosodium urat pada sendi. Sosialisasi kesehatan merupakan upaya perubahan perilaku manusia yang dilakukan melalui pendekatan edukatif. Tujuan enelitian ini mengetahui pengaruh sosialisasi kesehatan mengenai penyakit asam urat terhadap peningkatan pengetahuan pada tokoh masyarakat. Desain penelitian adalah pra eksperimental one group pra test post test design. Sampel yang diambil sebanyak 70 responden yang berasal dari tokoh masyarakat di Kelurahan Kutobatu Palembang, Sumatera Selatan. Data penelitian ini di ambil dengan menggunakan kuesioner. Data dianalisis dengan mengunakan uji wilcoxon dengan tingkat kemaknaan 0,05. Hasil penelitian menunjukan tingkat pengetahuan sebelum intervensi berada pada kategori kurang dengan persentase 75% dan sesudah intervensi berada pada kategori baik dengan persentase 90%. Hasil uji statistic wilcoxon dimana p-value=0,02 < α=0,05. Dapat disimpulkan terdapat pengaruh sosialisasi kesehatan terhadap peningkatan pengetahuan tokoh masyarakat di Kelurahan Kutobatu Palembang, Sumatera Selatan.
Neuropsychiatric Aspects of Long Covid Bintang Arroyantri Prananjaya; Muhammad Yusuf Wijahaska; Chris Alberto Amin; Carissa Delania; Ziske Maritska; Nita Parisa; Mohammad Hilal Atthariq Ramadhan
Biomedical Journal of Indonesia Vol. 8 No. 1 (2022): Vol 8, No 1, 2022
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/BJI.v8i1.125

Abstract

Long COVID is a term used for persistent symptoms after being infected with COVID-19 with an estimated point of onset ranging from 3-12 weeks after infection. The risk factors for the occurrence of Long COVID are influenced by age, gender, comorbidity, ethnicity, and the severity of the acute phase. It is known that central, peripheral, and psychological factors play an important role in chronic fatigue, which is one of the most common symptoms of Long COVID. The most common neuropsychiatric clinical manifestations in Long COVID are sleep disturbances, fatigue, depression, anxiety disorders, decreased cognitive function or decreased concentration, and post-traumatic stress disorder. Therapeutic management for Long COVID cases involves various aspects, such as physical rehabilitation, management of pre-existing co-morbidities, mental health support management, and social services.
Neuroprotective Effect Of Angiotensin Receptor Blocker Syarinta Adenina; Nita Parisa; Rulan Adnindya
Biomedical Journal of Indonesia Vol. 8 No. 2 (2022): Vol 8, No 2, 2022
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/BJI.v8i2.152

Abstract

Angiotensin Receptor Blocker, ARB, is a drug that acts on the AT1 receptor so as to inhibit Ang II stimulation. Ang II stimulates the main activity of the angiotensin renin system. Recent research has shown the presence of components of the RAS system in the brain, and the neuroprotective effects of the brain. ARB drugs can enter the brain and protect the blood brain flow, maintain the function of the blood brain barrier and reduce cerebral hemorrhage. The neuroprotective effect of ARB not only arises from improved cerebrovascular blood flow (improved access to oxygen and nutrients) but also decreased factors that can cause brain injury, including decreased excitotoxicity of glutamate which causes inflammatory response and apoptosis, decreased inflammatory response of interleukin-1β and bacterial endotoxin. In addition, there are additional effects through the PPARγ activation mechanism. Based on these benefits ARBs can be developed for the purpose of treating various brain disorders, in this case improving cognitive function, such as vascular dementia, Alzheimer's disease, Parkinson's disease, traumatic brain injury, stroke, and others.
Prescription Profile of Anti-inflamatory Drugs After Excision Biopsy of Oral Soft Tissue Disease in Palembang Kemas Muhammad Deky Berryl Ananta Putra; Siti Rusdiana Puspa; Nita Parisa
Sriwijaya Journal of Dentistry Vol. 3 No. 2 (2022): Sriwijaya Journal of Dentistry
Publisher : Dentistry Study Program, Faculty of Medicine Universitas Sriwijaya 

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjd.v3i2.30

Abstract

Introduction: Oral soft tissue lesion is an abnormal condition of the oral soft tissue. Clinically this lesion can be seen from the changes of colour and size in the surface of the oral soft tissues. There are various types of lesions in the oral cavity, including primary and secondary lesions. The treatment of each lesion is also different, it can be with non-surgical treatment, or surgical treatment. Biopsy is a surgical treatment procedure where tissue is taken for histopathological examination. The purpose of biopsy is to help establish a diagnosis and determine the prognosis of a treatment. After an excisional biopsy, dentists usually give patients anti-inflammatory as a pain control. Anti-inflammatory drugs devide into two groups, steroid and non-steroidal drugs. The most commonly used are non-steroidal groups. The use of anti-inflammatory drugs is seen based on the best therapeutic effects and the fewest side effects. Purpose: The purpose of this study was to examine the prescription profile of anti-inflammatory drugs after excision biopsy of soft tissue disease performed by dentists in Palembang. Method: This research was a descriptive study with survey technique. This research was conducted at the dentist's practice and the hospital's dental clinic in Palembang. Data was collected using a questionnaire form which was filled in by the respondents themselves. The questionnaire consists of several questions that were considered representative to find out how the prescription profile of anti-inflammatory use after excision biopsy of oral soft tissue disease by dentists and or specialist in Palembang. Results: The results of the study showed that the frequency distribution of anti-inflammatory drugs used by dentists in Palembang after excision biopsy was diclofenac (52.5%) and tablet preparations are the main choice (92.5%). Conclusion: The most widely used prescription of anti-inflammatory drugs after excision biopsy of oral soft tissue disease by dentists in Palembang was diclofenac, and tablet preparation of anti-inflammatory drugs was most prescribed by dentist in Palembang.
The Impact of Sambiloto Extract (Andrographis paniculata) as a Potential Antidiabetic Treatment Clara Alverina; Nita Parisa; Rio Dwi Arliansyah; Nia Savitri Tamzil
Biomedical Journal of Indonesia Vol. 10 No. 2 (2024): Vol 10, No 2, 2024
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v10i2.190

Abstract

Diabetes mellitus (DM) is a metabolic disease caused by an inappropriate increase in blood glucose levels. The development of traditional medicines, including extracts, fractions, and isolates from plants, remains highly intriguing and challenging. Andrographis paniculata is a one of medicinal plants with a long history of use in Asia for the treatment of various ailments. Andrographolide, a bioactive compound found in A. paniculata, has been extensively studied for its medicinal benefits, specifically its antidiabetic effects. This study employs a literature review approach to investigate the effect of Sambiloto extract (Andrographis paniculata) as an antidiabetic medication using Google Scholar, Science Direct, and PubMed databases. The publication year range for the literature data sources is from 2020 to 2024. Based on the conducted searches, three reference journals are included in this study. Andrographolide, the active compound contained in Sambiloto, may act as an antidiabetic medication through various mechanisms, thus representing a potential treatment for diabetes mellitus.
Pendampingan pemanfaatan tanaman herbal pada pasien hipertensi dan diabetes melitus sebagai upaya pencegahan penyakit gagal ginjal di Puskesmas Gandus Palembang Lusiana, Evi; Kurniati, Ardesy Melizah; Harahap, Debby Handayati; Tamzil, Nia Savitri; Parisa, Nita; Adenina,  Masayu Syarinta; Rosdah, Ayesha Augusta; Oktariana, Desi; Pariyana, Pariyana; Azizah, Aida Nur; Islami, Arya Putera
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 5 No 1 (2024): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V5I1.138

Abstract

Hypertension and diabetes mellitus are risk factors for chronic kidney disease. A person diagnosed with hypertension and diabetes mellitus is required to regularly take medication for life, which can lead to side effects of drugs (ESO). This triggers the search for more effective and safer drugs, so many people start to turn to traditional medicine. The main objective of this community service is to increase community knowledge and skills through assistance in cultivating herbal plants such as Sambiloto, Celery, and Ginger. The method of service carried out in this activity is by giving questionnaires before and after the delivery of material with the community in the working area of the Gandus Palembang Health Center. The targets of community service activities are hypertension and diabetes mellitus patients and the community registered in the working area of the Gandus Palembang Health Center as many as 30 participants. The results of the counseling showed that there was an increase in the results of participants who fell into the good category, according to the variables of knowledge, attitude and action respectively 56.7%, 23.3% and 40%.
Promosi Kesehatan Jiwa Berbasis Media Sosial (Instagram Live) Bagi Masyarakat di Masa Pandemi COVID-19 Maritska, Ziske; Prananjaya, Bintang Arroyantri; Nabila, Safa Putri; Parisa, Nita
Wal'afiat Hospital Journal Vol 4 No 1 (2023): Wal'afiat Hospital Journal
Publisher : Rumah Sakit Ibnu Sina, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/whj.v4i1.98

Abstract

Pandemi COVID-19 yang telah berlangsung selama dua tahun terakhir menyebabkan disrupsi layanan kesehatan di berbagai bidang kesehatan tanpa terkecuali termasuk layanan kesehatan jiwa di seluruh negara di dunia. Tinjauan pustaka ini bertujuan untuk mengeksplorasi potensi media sosial sebagai media promosi kesehatan jiwa di masa pandemi COVID-19. Penelusuran literatur dilakukan di 2 situs pencari (Google Scholar dan PubMed) yang memenuhi kriteria inklusi dan ekslusi. Dari hasil penelurusuran diketahui bahwa media sosial sering dijadikan sebagai sarana untuk berbagi informasi dengan banyak orang lainnya. Aksesnya yang relatif mudah menjadikan media sosial sebagai platform berbagi yang cukup efektif dengan jangkauan yang luas. Salah satu platform media sosial yang banyak digunakan oleh masyarakat dari berbagai latar belakang dan usia adalah Instagram. Penggunaan Instagram sebagai salah satu media edukasi atau penyuluhan kesehatan yang murah, dan mudah untuk diakses masyarakat luas merupakan salah satu opsi yang efektif dalam upaya promosi kesehatan di masa pandemi. Berbagai studi menunjukkan bahwa penggunaan media sosial berdampak positif terhadap upaya promosi kesehatan termasuk promosi kesehatan jiwa. Berdasarkan hasil survey WHO di akhir tahun 2021, didapatkan masih banyak masyarakat yang tidak dapat mengakses layanan kesehatan baik di tingkat perawatan primer maupun lanjut di era pandemi COVID-19. Situasi ini dapat berdampak pada information flow di dunia kedokteran dan kesehatan di mana dikhawatirkan dapat menyebabkan tersebarnya informasi kesehatan yang menyesatkan (misleading atau false information/hoax). Karena keterbatasan interaksi sosial akibat situasi pandemi, salah salah satu metode yang dapat digunakan untuk melaksanakan promosi kesehatan sekaligus penyuluhan/edukasi tentang berbagai topik kesehatan yang dapat diakses oleh masyarakat luas adalah dengan menggunakan media sosial.
Extract Ethanol of Tempuyung (Sonchus arvensis) Leaves as Anti-Hyperuricemia: In Vitro Studies Parisa, Nita; Hidayat, Rachmat; Fatmawati, Fatmawati
Medical Laboratory Technology Journal Vol. 10 No. 1 (2024): June
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/mltj.v10i1.594

Abstract

Hyperuricemia is a condition where there is an increase in blood uric acid levels above 7 mg/dL in men and 6 mg/dl in women. One of the enzymes that plays a role in hyperuricemia is xanthine oxidase which can inhibit uric acid synthesis. Tempuyung leaves (Sonchus avernis) are one of the plants that have antihyperuricemia properties. This study aims to determine the effect of ethanol extract of tempuyung leaves on xanthine oxidase in vitro. Tempuyung leaves come from Palembang, South Sumatra, Indonesia, and are macerated with 96% ethanol until a thick extract is obtained. The xanthine oxidase inhibition test was carried out on tempuyung leaf extract and Allopurinol with respective concentrations of 6.25; 12.5; 25; and 50 ppm and followed by absorption measurements using UV-V spectrophotometry at a wavelength of 293 nm and determining the IC50 value. The research results showed that the ethanol extract of daun tempuyung leaves had an IC50 value of 23.37 ppm, higher than allopurinol of 17.16 ppm which was used as a reference. These results classify the ethanol extract of daun tempuyung leaves as a strong inhibitor of the xanthin oxidase enzyme. Therefore, the ethanol extract of daun tempuyung leaves has the potential to be anti hyperuricemic.
Anti-hyperuricemia Potential of Ethyl Acetate Fraction from Ethanolic Stem Extract of Arcangelisia flava Fatmawati, Fatmawati; Saleh, Irsan; Parisa, Nita; Salni, Salni; Izzah, Puspita Nurul; Subandrate, Subandrate; Athiah, Medina
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.13510

Abstract

Arcangelisia flava, with its secondary metabolites in flavonoids, has shown promising potential as an alternative treatment for hyperuricemia. The study aimed to determine the effectiveness of the ethyl acetate fraction from the ethanolic stem extract of Arcangelisia flava in inhibiting xanthine oxidase. This research, conducted at the Medical Basic Chemistry Laboratory Universitas Sriwijaya in September–December 2022, used in vitro study methods. The stem of Arcangelisia flava was extracted by maceration using ethanol. The ethanolic stem extract of Arcangelisia flava was then fractionated using n-hexane and ethyl acetate. The ethyl acetate fraction and ethanolic extract of Arcangelisia flava were measured to inhibit the xanthine oxidase using UV-vis spectrophotometry with allopurinol as a comparison. The IC50 was calculated by linear regression. The ethanol extract and ethyl acetate fraction have flavonoids, alkaloids, terpenoids, and quinones. The IC50 value of the ethanol extract was 30.04 ppm, the ethyl acetate fraction was 23.99 ppm, and the allopurinol was 17.16 ppm. The ethyl acetate fraction inhibited xanthine oxidase better than the ethanol extract. The study's significant finding is that the ethyl acetate fraction of the ethanolic stem extract of Arcangelisia flava strongly inhibits xanthine oxidase, offering a potential new avenue for treating hyperuricemia.
Co-Authors ., Mariana Abdulwahab Hakimi Adenina, Masayu S Agustina Septi Hijir Aini, Nurlutfiyyah Aisyah Fristania Ditamor Alfiyah Munawwaroh Abdullah Alwi Shahab Amira Azra Arisa Putri Amirah Dhia Nabila Sinum Anisah Nida'ul Haq Aprilia Paskah Samosir Ardesy Melizah Kurniati Ardesy Melizah Kurniati Ardy Oktaviandi Arroyantri Prananjaya, Bintang Athiah, Medina Atikah M. Ihsan Ayeshah A Rosdah Az Zahra, Zaviera Azizah, Aida Nur Bagaskara, Surya Bintang Arroyantri Bintang Arroyantri P Bintang Arroyantri Prananjaya Bintang Arroyantri Prananjaya Bintang Arroyantri Prananjaya Bintang Arroyantri Prananjaya Carissa Delania Chris Alberto Amin Citra Yuliana Clara Alverina Dara Prameswari Debby Handayati Harahap Desi Oktariana Diah Andini Diba, Msy. Farah Diyaz Syauki Ikhsan Dwi Tantri Marylin Eka Febri Zulissetiana Ella Amalia, Ella Emelda Emelda Eskalatin, Khaira Evi Lusiana Fakhri Abdurrahman Fakhri Abdurrahman Fatmawati Fatmawati Fatmawati Fatmawati Fatmawati Fatmawati Fatmawati Fatmawati, Fatmawati Febryana Ramadhani Machyar Gita Dwi Prasasty Gita Dwi Prasasty Haq, Anisah Nida'ul Hawari Martanusa Ina Rahmawati Indri Seta Septadina Inggarsih, Rara Irga, Muhammad Islami, Arya Putera Izzah, Puspita Nurul Jayawarsa, A.A. Ketut Joko Marwoto Kamaluddin, Muhammad Totong Karina Nurul Fahira Karina, Mathius Kemas Muhammad Deky Berryl Ananta Putra Larasati, Veny Leonardo Satria Lusia Hayati Lusia Hayati, Lusia M. Ivan Pratama M. Khairul Kahfi Pasaribu M. T. Kamaluddin M. T. Kamaluddin M. Totong Kamaluddin Manurung, Maya Rina Santara Maria Sidabutar, Carolina Marlyani Tamara Mayasari Mayasari Mgs Irsan Saleh Mgs Irsan Saleh Mgs. Irsan Saleh Mgs. Irsan Saleh, Mgs. Irsan Mohammad Hilal Atthariq Ramadhan MT Kamaluddin Muhammad Barkah Muhammad Fakhri Altyan Muhammad Irsan Saleh Muhammad Reagen Muhammad Totong Kamaluddin Muhammad Totong Kamaluddin Muhammad Yusuf Wijahaska Nabila, Safa Putri Nadhila Apriadhanti Nafrah Ardita Nashif, Arkan Abdullah Nia Savitri Tamzil Noviyanti Eliska, Noviyanti Nugraha, M Daffa Oktariana, Desi pariyana, Pariyana Pasaribu, Rouly Pola Perawati Perawati Perryanis Perryanis Perryanis, Perryanis Prananjaya, Bintang A Prananjaya, Bintang Arroyantri Puji Rizki Suryani Purnamasari, Septi Putra, Marco Manza R.A. Alda Adelia RACHMAT HIDAYAT Rachmat Hidayat Rachmat Taufan Radiyati Umi Partan Rahma Nur Islami Rahmat Hidayat Rahmat Hidayat Rahmi Isman Rasyid, Riana Sari Puspita Rini Nindela Rini Nindela Rio Dwi Arliansyah Rischka Salsabila Maulini Rohaya Rohaya Rosdah, Ayesha Augusta Rovania Yantinez Quardetta Rovania Yantinez Quardetta Rulan Adnindya Safira Azahra Saleh, M. Irsan Saleh, Masagus I Salni Salni Salni Salni Salni Samantha Ferlin Boentara Samantha Ferlin Boentara Saputra, Andre Sativandi Riza Sindy Bintang Permata Siti Rusdiana Puspa Siti Rusdiana Puspa Dewi Smaradhna, Safira Sri Nita Sri Nita Subandrate Sutandar, Vivi Hendra Syarinta Adenina Syifa Syifa Syifa Tahany, Hanifah Tantoro, Valyn T Theodorus Theodorus Theodorus Parulian Theodorus Parulian Theodorus Theodorus Theodorus Theodorus Theodorus Theodorus Tiara Fatrin tri wahyuni Tri Wahyuni Triwani Triwani Triwani Triwani Triwani Triwani Triwani Triwani Try Merdeka Puri Tryvanie R Putra Uswati Uswati Valentino, Albert Amadeus Venny Larasati Vincensius Hans Kristian Pratama Wicaksono, Bonanza Abi Wildan Dwi Putra Widodo Yeni Agustin Yeni Agustin Yeni Agustin Yuliana, Citra Yuliarni Yuliarni Yuliarni Yuliarni Zabila Adwie Prilishia Ziske Maritska