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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Global Medical and Health Communication Majalah Kedokteran Sriwijaya Biomedical Journal of Indonesia Padjadjaran Journal of Dentistry Medical Laboratory Technology Journal Indonesian Journal for Health Sciences (IJHS) SRIWIJAYA JOURNAL OF MEDICINE Jurnal Jamu Indonesia Jurnal Mandala Pharmacon Indonesia Scientia Psychiatrica Indonesian Journal of Anesthesiology and Reanimation (IJAR) JK Unila (Jurnal Kedokteran Universitas Lampung) Eureka Herba Indonesia Jurnal Pengabdian Masyarakat: Humanity and Medicine Journal of Community Development Indonesian Community Empowerment Journal Archives of The Medicine and Case Reports Bioscientia Medicina : Journal of Biomedicine and Translational Research Arkus Wal'afiat Hospital Journal International Journal of Islamic and Complementary Medicine Conferences of Medical Sciences Dies Natalis Sriwijaya Journal of Dentistry WAL'AFIAT HOSPITAL JOURNAL Media Penelitian dan Pengembangan Kesehatan Indonesian Journal of Jamu Journal of Medicine and Health
Nita Parisa
Department Of Pharmacology, Faculty Of Medicine, Universitas Sriwijaya, Palembang, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Drug Pattern Study on ARB at the Outpatient Department of Mohammad Hoesin General Public Hospital Palembang Samantha Ferlin Boentara; Nita Parisa; Theodorus Parulian
Majalah Kedokteran Sriwijaya Vol 54, No 4 (2022): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/mks.v54i4.18899

Abstract

Backgrounds. Hypertension is a global health problem due to its increasing prevalence. Hypertension is a condition where there is a persistent increase in blood pressure exceeding 140/90 mmHg. Among the many choices of antihypertensive drug classes, ARB is one of the first-line drug classes for the treatment of hypertension. Inappropriate ARB administration can reduce the effectiveness of treatment and harm the patient. This study aims to determine the pattern of ARB use in hypertensive patients. Methods. This drug pattern study has been done on October – November 2021 at the Outpatient Department of Dr. Mohammad Hoesin Central Public Hospital Palembang. The sample was using the medical record data of all hypertensive patients period of July – December 2020 who met the inclusion criteria, with a total of 171 data. The data was processed by using the SPSS v25 and presented in the form of a table with a descriptive explanation referring to the research variables. Results. This study found that the prevalence of ARB use was 59.0% with the highest was in male (30.4%) and age group 41-60 years (29.2%). The most widely used ARB is candesartan (94.0%) at a dose of 16 mg (52.6%), frequency once a day (97.9%) and duration more than one month (93.7%). The drug prescribed to the patient mostly didn’t have interaction with ARB (33.0%). Conclusions. The prevalence of ARB administration is high in hypertensive patients (59.0%) with the most commonly used ARB is candesartan (94.0%).
GENETICS OF DEMENTIA: THE CANDIDATE GENES AND AVAILABLE GENETIC TESTINGS Ziske Maritska; Diah Andini; Febryana Ramadhani Machyar; Rachmat Taufan; Try Merdeka Puri; Tryvanie R Putra; Uswati Uswati; Bintang Arroyantri Prananjaya; Rini Nindela; Nita Parisa
Indonesian Journal for Health Sciences Vol 7, No 2 (2023): September
Publisher : Universitas Muhammadiyah Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24269/ijhs.v7i2.6353

Abstract

When dementia is present, a person's memory, reasoning, behavior, and even their capacity to carry out day-to-day chores can all become distorted. This syndrome remains present and actually worsens as time passes. It's possible that synapse loss, death and dysfunction of brain cells, gliosis, and inflammation are all factors in the progression of dementia. The clinical syndrome, age, and a history of the ailment in the patient's family should dictate the choices made about counseling and testing. Dementia is known as a multifactorial condition, brought on by the combination of strong genetic factors and environmental factors. There are several candidate genes  associated with Dementia; APP, PSEN1, and PSEN2 genes, in addition to the GRN and MAPT genes. This literatura review provide insight on the genetic of Dementia, particularly in the genetic causes and testings
THE POTENTIAL OF BAY LEAVE (SYZYGIUM POLYANTHUM) AS AN ANTI-DIABETIC AGENT Wildan Dwi Putra Widodo; Nita Parisa; Nia Savitri Tamzil; Evi Lusiana; Nafrah Ardita; Amira Azra Arisa Putri; Sindy Bintang Permata; Aisyah Fristania Ditamor
International Journal of Islamic and Complementary Medicine Vol. 4 No. 2 (2023): International Journal of Islamic and Complementary Medicine
Publisher : International Islamic Medicine Forum

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55116/IJICM.V4I2.60

Abstract

Non-communicable disease prevalence continues to increase in Indonesia. One of the top 10 causes of death is non-communicable disease, and diabetes mellitus is on the list. Genetics, advanced age, obesity, stress, hypertension, smoking, and physical inactivity are risk factors that might result in diabetes mellitus. Despite advancements in mainstream anti-diabetic treatment, traditional medical practices continue to exist in several nations. Syzygium polyanthum is the herb that diabetic patients most frequently utilize in the traditional therapy of their illness, according to research on diabetic patients at the Health Community Center in Sering, Medan, Indonesia. The research team was interested in figuring out whether bay leaves showed any potential as an anti-diabetic agent based on the previous description. In this study, secondary literature from research publications is used in a literature review with a descriptive method. Several studies have suggested that bay leaves could potentially be used for the prevention and treatment of diabetes mellitus.
Down Syndrome : Through The Eyes of The Parents Ziske Maritska; Fakhri Abdurrahman; Bintang Arroyantri Prananjaya; Nita Parisa; Syifa; Triwani
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 5 No. 3 (2018): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universi
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v5i3.106

Abstract

Sindroma Down merupakan salah satu kejadian kelainan kromosom tipe aneuploidi yang kerap ditemukan. Kejadian Sindroma Down terkait erat dengan disabilitas intelektual dan stugma sosial yang melekat padanya. Pandangan orang tua mengenai Sindroma Down yang tercerminkan melalui perilaku amat penting karena dukungan keluarga merupakan salah satu kunci utama untuk mengoptimalkan kualitas hidup penyandang Sindroma Down. Studi ini merupakan studi deskriptif pada orang tua penyandang Sindroma Down yang bersekolah di Sekolah Luar Biasa (SLB) di Palembang. Perilaku orang tua diukur dengan menggunakan kuesioner HealthStyles©. Sebagian besar orang tua penyandang Sindroma Down sepakat bahwa anak dengan Sindroma Down harus bersekolah di SLB (82,5%) karena mayoritas meyakini pencampuran penyandang Sindroma Down di sekolah biasa dapat mengganggu murid lain (60%). Namun orang tua memiliki pandangan optimis bahwa anak penyandang Sindroma Down dapat bekerja jika telah dewasa (72,5%). Mereka pun percaya bahwa penyandang Sindroma Down tidak lebih rentan mengalami kecelakaan kerja di tempat kerja (37,5%). Dari studi ini terlihat bahwa orang tua penyandang Sindroma Down memiliki perilaku yang bervariasi tergantung dari aspek mana mereka memandang Sindroma Down.
Optimalisasi Pengetahuan Tokoh Masyarakat Mengenai Penyakit Asam Urat Melalui Sosialisasi Kesehatan Evi Lusiana; Nia Savitri Tamzil; Nita Parisa; Desi Oktariana; Gita Dwi Prasasty; Indri Seta Septadina
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 9 No. 1 (2022): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universi
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v9i1.209

Abstract

Penyakit asam urat merupakan dalah satu penyakit yang banyak diderita masyarakat yang ditandai dengan rasa nyeri pada persendian yang disebabkan endapan kristal monosodium urat pada sendi. Sosialisasi kesehatan merupakan upaya perubahan perilaku manusia yang dilakukan melalui pendekatan edukatif. Tujuan enelitian ini mengetahui pengaruh sosialisasi kesehatan mengenai penyakit asam urat terhadap peningkatan pengetahuan pada tokoh masyarakat. Desain penelitian adalah pra eksperimental one group pra test post test design. Sampel yang diambil sebanyak 70 responden yang berasal dari tokoh masyarakat di Kelurahan Kutobatu Palembang, Sumatera Selatan. Data penelitian ini di ambil dengan menggunakan kuesioner. Data dianalisis dengan mengunakan uji wilcoxon dengan tingkat kemaknaan 0,05. Hasil penelitian menunjukan tingkat pengetahuan sebelum intervensi berada pada kategori kurang dengan persentase 75% dan sesudah intervensi berada pada kategori baik dengan persentase 90%. Hasil uji statistic wilcoxon dimana p-value=0,02 < α=0,05. Dapat disimpulkan terdapat pengaruh sosialisasi kesehatan terhadap peningkatan pengetahuan tokoh masyarakat di Kelurahan Kutobatu Palembang, Sumatera Selatan.
Neuropsychiatric Aspects of Long Covid Bintang Arroyantri Prananjaya; Muhammad Yusuf Wijahaska; Chris Alberto Amin; Carissa Delania; Ziske Maritska; Nita Parisa; Mohammad Hilal Atthariq Ramadhan
Biomedical Journal of Indonesia Vol. 8 No. 1 (2022): Vol 8, No 1, 2022
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/BJI.v8i1.125

Abstract

Long COVID is a term used for persistent symptoms after being infected with COVID-19 with an estimated point of onset ranging from 3-12 weeks after infection. The risk factors for the occurrence of Long COVID are influenced by age, gender, comorbidity, ethnicity, and the severity of the acute phase. It is known that central, peripheral, and psychological factors play an important role in chronic fatigue, which is one of the most common symptoms of Long COVID. The most common neuropsychiatric clinical manifestations in Long COVID are sleep disturbances, fatigue, depression, anxiety disorders, decreased cognitive function or decreased concentration, and post-traumatic stress disorder. Therapeutic management for Long COVID cases involves various aspects, such as physical rehabilitation, management of pre-existing co-morbidities, mental health support management, and social services.
Neuroprotective Effect Of Angiotensin Receptor Blocker Syarinta Adenina; Nita Parisa; Rulan Adnindya
Biomedical Journal of Indonesia Vol. 8 No. 2 (2022): Vol 8, No 2, 2022
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/BJI.v8i2.152

Abstract

Angiotensin Receptor Blocker, ARB, is a drug that acts on the AT1 receptor so as to inhibit Ang II stimulation. Ang II stimulates the main activity of the angiotensin renin system. Recent research has shown the presence of components of the RAS system in the brain, and the neuroprotective effects of the brain. ARB drugs can enter the brain and protect the blood brain flow, maintain the function of the blood brain barrier and reduce cerebral hemorrhage. The neuroprotective effect of ARB not only arises from improved cerebrovascular blood flow (improved access to oxygen and nutrients) but also decreased factors that can cause brain injury, including decreased excitotoxicity of glutamate which causes inflammatory response and apoptosis, decreased inflammatory response of interleukin-1β and bacterial endotoxin. In addition, there are additional effects through the PPARγ activation mechanism. Based on these benefits ARBs can be developed for the purpose of treating various brain disorders, in this case improving cognitive function, such as vascular dementia, Alzheimer's disease, Parkinson's disease, traumatic brain injury, stroke, and others.
Prescription Profile of Anti-inflamatory Drugs After Excision Biopsy of Oral Soft Tissue Disease in Palembang Kemas Muhammad Deky Berryl Ananta Putra; Siti Rusdiana Puspa; Nita Parisa
Sriwijaya Journal of Dentistry Vol. 3 No. 2 (2022): Sriwijaya Journal of Dentistry
Publisher : Dentistry Study Program, Faculty of Medicine Universitas Sriwijaya 

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjd.v3i2.30

Abstract

Introduction: Oral soft tissue lesion is an abnormal condition of the oral soft tissue. Clinically this lesion can be seen from the changes of colour and size in the surface of the oral soft tissues. There are various types of lesions in the oral cavity, including primary and secondary lesions. The treatment of each lesion is also different, it can be with non-surgical treatment, or surgical treatment. Biopsy is a surgical treatment procedure where tissue is taken for histopathological examination. The purpose of biopsy is to help establish a diagnosis and determine the prognosis of a treatment. After an excisional biopsy, dentists usually give patients anti-inflammatory as a pain control. Anti-inflammatory drugs devide into two groups, steroid and non-steroidal drugs. The most commonly used are non-steroidal groups. The use of anti-inflammatory drugs is seen based on the best therapeutic effects and the fewest side effects. Purpose: The purpose of this study was to examine the prescription profile of anti-inflammatory drugs after excision biopsy of soft tissue disease performed by dentists in Palembang. Method: This research was a descriptive study with survey technique. This research was conducted at the dentist's practice and the hospital's dental clinic in Palembang. Data was collected using a questionnaire form which was filled in by the respondents themselves. The questionnaire consists of several questions that were considered representative to find out how the prescription profile of anti-inflammatory use after excision biopsy of oral soft tissue disease by dentists and or specialist in Palembang. Results: The results of the study showed that the frequency distribution of anti-inflammatory drugs used by dentists in Palembang after excision biopsy was diclofenac (52.5%) and tablet preparations are the main choice (92.5%). Conclusion: The most widely used prescription of anti-inflammatory drugs after excision biopsy of oral soft tissue disease by dentists in Palembang was diclofenac, and tablet preparation of anti-inflammatory drugs was most prescribed by dentist in Palembang.
The Impact of Sambiloto Extract (Andrographis paniculata) as a Potential Antidiabetic Treatment Clara Alverina; Nita Parisa; Rio Dwi Arliansyah; Nia Savitri Tamzil
Biomedical Journal of Indonesia Vol. 10 No. 2 (2024): Vol 10, No 2, 2024
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v10i2.190

Abstract

Diabetes mellitus (DM) is a metabolic disease caused by an inappropriate increase in blood glucose levels. The development of traditional medicines, including extracts, fractions, and isolates from plants, remains highly intriguing and challenging. Andrographis paniculata is a one of medicinal plants with a long history of use in Asia for the treatment of various ailments. Andrographolide, a bioactive compound found in A. paniculata, has been extensively studied for its medicinal benefits, specifically its antidiabetic effects. This study employs a literature review approach to investigate the effect of Sambiloto extract (Andrographis paniculata) as an antidiabetic medication using Google Scholar, Science Direct, and PubMed databases. The publication year range for the literature data sources is from 2020 to 2024. Based on the conducted searches, three reference journals are included in this study. Andrographolide, the active compound contained in Sambiloto, may act as an antidiabetic medication through various mechanisms, thus representing a potential treatment for diabetes mellitus.
Extract Ethanol of Tempuyung (Sonchus arvensis) Leaves as Anti-Hyperuricemia: In Vitro Studies Parisa, Nita; Hidayat, Rachmat; Fatmawati, Fatmawati
Medical Laboratory Technology Journal Vol. 10 No. 1 (2024): June
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/mltj.v10i1.594

Abstract

Hyperuricemia is a condition where there is an increase in blood uric acid levels above 7 mg/dL in men and 6 mg/dl in women. One of the enzymes that plays a role in hyperuricemia is xanthine oxidase which can inhibit uric acid synthesis. Tempuyung leaves (Sonchus avernis) are one of the plants that have antihyperuricemia properties. This study aims to determine the effect of ethanol extract of tempuyung leaves on xanthine oxidase in vitro. Tempuyung leaves come from Palembang, South Sumatra, Indonesia, and are macerated with 96% ethanol until a thick extract is obtained. The xanthine oxidase inhibition test was carried out on tempuyung leaf extract and Allopurinol with respective concentrations of 6.25; 12.5; 25; and 50 ppm and followed by absorption measurements using UV-V spectrophotometry at a wavelength of 293 nm and determining the IC50 value. The research results showed that the ethanol extract of daun tempuyung leaves had an IC50 value of 23.37 ppm, higher than allopurinol of 17.16 ppm which was used as a reference. These results classify the ethanol extract of daun tempuyung leaves as a strong inhibitor of the xanthin oxidase enzyme. Therefore, the ethanol extract of daun tempuyung leaves has the potential to be anti hyperuricemic.
Co-Authors ., Mariana Abdulwahab Hakimi Adenina, Masayu S Adnindya, Rulan Agustina Septi Hijir Aida Nur Azizah Aini, Nurlutfiyyah Aisyah Fristania Ditamor Alfian Hasbi Alfiyah Munawwaroh Abdullah Alwi Shahab Amira Azra Arisa Putri Amirah Dhia Nabila Sinum Anisah Nida'ul Haq Aprilia Paskah Samosir Ardesy Melizah Kurniati Ardesy Melizah Kurniati Ardy Oktaviandi Arroyantri Prananjaya, Bintang Arya Putera Islami Athiah, Medina Atikah M. Ihsan Ayesha Augusta Rosdah Ayeshah A Rosdah Ayeshah Rosdah Az Zahra, Zaviera Bintang Arroyantri Bintang Arroyantri P Bintang Arroyantri Prananjaya Bintang Arroyantri Prananjaya Bintang Arroyantri Prananjaya Bintang Arroyantri Prananjaya Bintang Arroyantri Prananjaya Carissa Delania Chris Alberto Amin Citra Yuliana Clara Alverina Dara Prameswari Debby Handayati Harahap Debby Handayati Harahap Debby Harahap Desi Oktariana Diah Andini Diba, Msy. Farah Diyaz Syauki Ikhsan Dwi Tantri Marylin Eka Febri Zulissetiana Ella Amalia, Ella Emelda Emelda Eskalatin, Khaira Evi Lusiana Fakhri Abdurrahman Fakhri Abdurrahman Fatmawati Fatmawati Fatmawati Fatmawati Fatmawati Fatmawati, Fatmawati Febryana Ramadhani Machyar Gita Dwi Prasasty Gita Dwi Prasasty Haq, Anisah Nida'ul Hawari Martanusa Ina Rahmawati Indri Seta Septadina Inggarsih, Rara Irga, Muhammad Izzah, Puspita Nurul Jayawarsa, A.A. Ketut Joko Marwoto Kamaluddin, Muhammad Totong Karina Nurul Fahira Karina, Mathius Kemas Muhammad Deky Berryl Ananta Putra Krisna Murti Kumar, Arun Leonardo Satria Lusia Hayati Lusia Hayati, Lusia M. Ivan Pratama M. Khairul Kahfi Pasaribu M. T. Kamaluddin M. T. Kamaluddin M. Totong Kamaluddin Manurung, Maya Rina Santara Maria Sidabutar, Carolina Marlyani Tamara Marsyadilla Putri Masayu Hanifah Mayasari Mayasari, Mayasari Mgs Irsan Saleh Mgs Irsan Saleh Mgs. Irsan Saleh Mgs. Irsan Saleh, Mgs. Irsan Mohammad Hilal Atthariq Ramadhan Msy. Adnindya MT Kamaluddin Muhammad Barkah Muhammad Fakhri Altyan Muhammad Irsan Saleh Muhammad Reagen Muhammad Totong Kamaluddin Muhammad Totong Kamaluddin Muhammad Yusuf Wijahaska Nadhila Apriadhanti Nafrah Ardita Nailah Nurhaura Nashif, Arkan Abdullah Nia Savitri Tamzil Noviyanti Eliska, Noviyanti Nugraha, M Daffa Oktariana, Desi Pariyana Pariyana Perawati Perawati Perryanis Perryanis Perryanis, Perryanis Prananjaya, Bintang A Puji Rizki Suryani Purnamasari, Septi Putra, Marco Manza R.A. Alda Adelia Rachmat Hidayat RACHMAT HIDAYAT Rachmat Taufan Radiyati Umi Partan Rahma Nur Islami Rahmat Hidayat Rahmat Hidayat Rahmi Isman Rasyid, Riana Sari Puspita Rini Nindela Rini Nindela Rio Dwi Arliansyah Rischka Salsabila Maulini Rohaya Rohaya Rovania Yantinez Quardetta Rovania Yantinez Quardetta Safa Putri Nabila Safira Azahra Saleh, M. Irsan Saleh, Masagus I Saleh, Muhammad Irsan Salni Salni Salni Salni Salni Samantha Ferlin Boentara Samantha Ferlin Boentara Saputra, Andre Sativandi Riza Sindy Bintang Permata Siti Rusdiana Puspa Siti Rusdiana Puspa Dewi Siti Rusdiana Puspa Dewi Smaradhna, Safira Sri Nita Sri Nita Subandrate Sutandar, Vivi Hendra Syarinta Adenina Syifa Syifa Syifa Tahany, Hanifah Tantoro, Valyn T Theodorus Theodorus Theodorus Parulian Theodorus Parulian Theodorus Theodorus Theodorus Theodorus Theodorus Theodorus Tiara Fatrin Tri Wahyuni tri wahyuni Triwani Triwani Triwani Triwani Triwani Triwani Triwani Triwani Try Merdeka Puri Tryvanie R Putra Uswati Uswati Valentino, Albert Amadeus Venny Larasati Veny Larasati Vincensius Hans Kristian Pratama Vivi Sutandar Wicaksono, Bonanza Abi Wildan Dwi Putra Widodo Yeni Agustin Yuliana, Citra Yuliarni Yuliarni Yuliarni Yuliarni Zabila Adwie Prilishia Ziske Maritska