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Early Marriage and Maternal History with Stunted Children Aged 24-59 Months in Mataram City Rosyida, Rufaida; Widyaningsih, Vitri; Nurwati, Ida
Al-Sihah : The Public Health Science Journal Volume 15, Nomor 2, July-December 2023
Publisher : Program Studi Kesehatan Masyarakat UIN Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-sihah.v15i2.41664

Abstract

The prevalence of stunting among children in 2021 and 2022 was 25.3% and 24.4% respectively, according to Indonesian Nutritional Status Survey in Mataram City. The Religious Court of NTB Province reported that the rate of early marriage among children was 16.59%. Therefore, this study aimed to analyze the relationship between early marriage and pregnancy history with stunted children in Mataram City. An analytical survey method was used with a case-control design, questionnaire, and anthropometric measurements conducted in a single session. The samples were selected using cluster random sampling, reaching 61 children aged 24-59 months for normal and stunted groups. The results showed that the samples were predominantly male, while increased weight during pregnancy <10 kg (p=0.009, OR=2.948, CI=1.285-6.766) and maternal height <150 cm (p=0.004, OR=2.937, CI=1.406-6.135) were associated with the incidence of stunted children. On the other hand, early marriage (p=0.926, CI=1.31) had no significant relationship with the incidence of stunting. A history of pregnancy and early marriage simultaneously influenced stunting by 30.5%, with the highest predictor being the height of the mother. Therefore, pregnancy history greatly influenced the incidence of stunting among children in Mataram City.
Correlation between circulating fibrosis biomarkers with left atrial function and left atrial volume index in rheumatic mitral stenosis Asrial, An A.; Reviono, Reviono; Soetrisno, Soetrisno; Setianto, Budi Y.; Widyaningsih, Vitri; Nurwati, Ida; Wasita, Brian; Pudjiastuti, Anggit
Narra J Vol. 4 No. 1 (2024): April 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i1.293

Abstract

Mitral stenosis is the most common rheumatic heart disease (RHD) disorder worldwide, including in Indonesia. This pathological condition causes left atrial pressure, leading to left atrial fibrosis that affects the structure and function of the left atrial as well as the clinical condition. The aim of this study was to assess the correlation between circulating fibrosis biomarkers with net atrioventricular compliance (Cn) as a parameter of left atrial function, and left atrial volume index (LAVI) as a parameter left atrium structure of changes. A cross-sectional study was conducted at Panti Rahayu Hospital and Permata Bunda Hospital, Purwodadi, Central Java, with a total of 40 RHD patients with severe mitral stenosis. The ELISA was used to measure the levels of carboxy-terminal propeptide of type I procollagen (PICP), matrix metalloproteinase I (MMP-1), tissue inhibitor matrix metalloproteinase 1 (TIMP-1), and transforming growth factor-β1 (TGF-β1). The left atrial function was assessed by measuring Cn, and the LAVI parameters were measured to assess left atrium structure/size. The mean levels of circulating fibrosis biomarkers were as follows: PICP 153.96±89.12 ng/mL; MMP-1 1.44±2.12 ng/mL; MMP-1/TIMP-1 ratio 0.38±0.54 and TGF-β1 2.66±1.96 pg/mL. From the echocardiographic evaluation, the mean Cn was 5.24±1.93 mL/mmHg and the mean LAVI was 152.55±79.36 mL/m2. There were significant correlation between MMP-1 and MMP-1/TIMP-1 ratio with Cn (r=0.345 and r=0.333, respectively; both had p<0.05). PICP and TGF-β1 biomarkers did not significantly correlate with Cn (p>0.05). Meanwhile, none of the biomarkers had a significant correlation with LAVI (p>0.05). This study highlights that MMP-1 and MMP-1/TIMP-1 ratio are potentially to be used as markers to determine the Cn in RHD patients with severe mitral stenosis. However, further studies with a higher sample size are needed to confirm this finding.
School-based sexual and reproductive health education among adolescents in developing countries Utami, Dyah Rahmawatie Ratna Budi; Nurwati, Ida; Lestari, Anik
International Journal of Public Health Science (IJPHS) Vol 13, No 1: March 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i1.23267

Abstract

The increase in risky sexual behavior among adolescents indicates the need to strengthen sexual and reproductive health. Schools have an essential role, but few studies are related to mapping models of school-based sex and reproductive education for adolescents in developing countries. This scoping review examines school-based sexual and reproductive health education among adolescents in developing countries. A systematic approach was used to search the literature through 5 electronic databases: Science Direct, EBSCO, PubMed, CrossReff, and Proquest. Subsequently, two reviewers conducted a conformity analysis with the inclusion/exclusion criteria, and then the search results that met the requirements were analyzed descriptively. A total of 14 articles met the inclusion criteria. The model of sexual health education in schools comprises digital-based education, peer groups, and comprehensive sex education to improve life skills. Barriers to implementation include culture, traditional norms, organization, commitment, and supporting resources. The supporting factors are student enthusiasm, exciting methods and media, community, and parental support. School-based sexual and reproductive education increases knowledge and attitudes about sexual health. Therefore, there is a need for a comprehensive sexual education model integrated into the school curriculum using attractive media and involving several well-organized stakeholders.
IS ANTENATAL CARE (ANC) EXAMINATION IMPORTANT FOR THE HEALTH OF THE MOTHER AND BABIES? Sari, Wahyu Anjas; Nurwati, Ida
Literasi Kesehatan Husada: Jurnal Informasi Ilmu Kesehatan Vol 7 No 3 (2023): Volume 7 Issue 3, Oktober 2023, Literasi Kesehatan Husada: Jurnal Informasi Ilmu
Publisher : Library Unit collaborates with the Institute for Research and Community Service, College of Health Sciences Husada Jombang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60050/lkh.v7i3.18

Abstract

Background: Maternal mortality and infant mortality are conditions that require special attention and immediate treatment. The antenatal care program is one way to reduce the increase in maternal mortality and infant mortality. Objective: This study aims to determine the importance of antenatal care examinations on the health of mothers and babies. Design: Scoping review was used in preparing this literature review. Data Sources: The researchers conducted a search using several search engines, including Google Scholar, DOAJ, Pubmed, EBSCO, and Sciencedirect with several inclusion criteria, including 1) Year of publication between 2019-2023, 2) Articles in English and Indonesian, and 3) Original articles, full text, and open access. Review Methods: The researchers carried out descriptive analysis and synthesis of the contents of all the articles, so that the researchers would be able to conclude the results of each research used as material in preparing this literature review. Results: Based on the results of the search conducted by the researchers, it was found that 5 articles were in accordance with the objectives of preparing this literature review. These articles show the importance of antenatal care (ANC) examinations for the health of mothers and babies, both during pregnancy and after birth. Conclusion: Implementing antenatal care services for pregnant women is very important because it can be related to the health of the mother and baby right up to the birth process. Apart from that, antenatal care services can detect early postnatal health problems, such as Low Birth Weight (LBW), Stunting, and so on.
The Potential of Durian Seed (Durio zibethinus Murr.) as Natural Resources with Antioxidant Activity and Total Flavonoid Content Aisyah, Siti; Harioputro, Dhani Redhono; Nurwati, Ida
Nusantara Science and Technology Proceedings The 1st International Conference of Health Institut Kesehatan Mitra Bunda 2024
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2024.4303

Abstract

Durian is mainly distributed in Southeast Asia and is already famous among Indonesian society. In addition, the nutritional content and unique flavor of the pulp, part of durian fruit such as the seed, peel, roots, and leaves also have many benefits. Durian seeds are known as inedible parts and should disposed of as food waste. However, these are a good source of bioactive compounds. Durian seeds contain bioactive compounds that are antioxidants, including phenolics, flavonoids, and alkaloids. Flavonoids are phenolic compounds which have good benefits for human health. This research aims to analyze the potential antioxidant activity and flavonoid content of durian seed waste. The extraction used ethanol 70%, the antioxidant activity test used a scavenging test to 2,2-diphenyl-1-pycryl-hydrazil (DPPH) radical, and total flavonoid content was determined by the UV-Vis spectrophotometry method. Based on the results, durian seed extract has antioxidant activity of 99.70 µg/ml and total flavonoid content of 23,24±0,39 mgQE/g. Durian seed extract has relatively strong antioxidant activity and contains flavonoids as a bioactive compound. This information is useful for researchers to find bioactive compounds that may be new nutraceuticals for antioxidants, anti-inflammatory, anti-diabetic, and therapeutic functional foods.
Nutrient Intake and Nutritional Status of Vegetarians Compared to Non-Vegetarians: A Systematic Literature Review Sineri, Dessy Ikasartika; Nurwati, Ida; Sumardiyono, S
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2023: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Purpose: A systematic literature review aims to analyze the nutritional intake and nutritional status among adult populations consuming vegetarian and non-vegetarian diets. Methodology: This study employed a systematic literature review (SLR) of journals published from 2013 to 2023. Articles were sourced from the Pubmed, Scopus, and Google Scholar databases. Articles are included if eligible. Results: The research posed specific research questions, and the findings indicated differences in nutrient intake and nutritional status between vegetarian and non-vegetarian populations. The nutritional intake and nutritional status of vegetarians showed better outcomes compared to non-vegetarians. However, dietary adjustments are necessary to ensure nutritional adequacy. Applications/Originality/Value: A systematic literature review contributes to comparing nutrient intake and nutritional status vegetarians and non-vegetarians. Systematic literature review of this study compares several articles with different research objects, research samples, methods and results.
The Effect of Durio Zibethinus L. Seed Extract on Fasting Blood Glucose and Insulin Resistance in Metabolic Syndrome Model Rats Aisyah, Siti; Harioputro, Dhani Redhono; Nurwati, Ida
Jurnal Kesehatan Manarang Vol 10 No 3 (2024): December 2024
Publisher : Politeknik Kesehatan Kemenkes Mamuju

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33490/jkm.v10i3.1526

Abstract

Metabolic syndrome is known as insulin resistance syndrome, characterized by chronic hyperglycemia. Management of metabolic syndrome involves several combinations, including lifestyle modifications and pharmacological interventions. Durian seeds are one source of antioxidants that have the potential to improve blood glucose homeostasis and insulin sensitivity. This study aims to analyze the effect of durian seed extract on changes in fasting blood glucose levels and insulin resistance. The extraction process utilized the maceration method with a 70% ethanol solution. This study consisted of 30 rats divided into six treatment groups: KN (normal group), K- (negative control), K+ (positive control metformin 9 mg/kgBW), P1, P2, and P3, which were given durian seed extract at doses of 100 mg/kgBW, 200 mg/kgBW, and 300 mg/kgBW, respectively. Metabolic syndrome rats were induced with a high-fat, high-fructose diet for 14 days, then induced with streptozocin (STZ) and nicotinamide (NA). Fasting blood glucose levels were determined using the GOD-PAP method. The HOMA-IR index was used to measure insulin resistance. The data results were evaluated using a paired T-test and one-way ANOVA. The analysis showed a significant variance in fasting blood glucose and HOMA-IR index following a 21-day treatment (p<0.05). The highest decrease was found in the 300 mg/kgBW dose group with fasting blood glucose and HOMA-IR index of 90.00 ± 2.70 mg/dl and 3.55 ± 0.11. The P2 and P3 treatments did not show different results with metformin treatment (p>0.05). The findings of this study suggest that consumption of durian seed extract for 21 days can effectively improve the condition of mice with metabolic syndrome. In addition, the drug metformin has the same effect as the intervention of durian seed extract doses of 200 and 300 mg/kgBW.
Effect of Cnidoscolus aconitifolius Leaf Extract in Lowering Triglyceride Levels and Body Weight of Wistar Rats with Metabolic Syndrome Sarsanti, Arifa Sherina Noor; Putranto, R. Prihandjojo Andri; Sarsono, Sarsono; Nurwati, Ida; Baihaqy, Fathu Thaariq
Althea Medical Journal Vol 11, No 3 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v11n3.3315

Abstract

Background: Cnidoscolus aconitifolius has the potential to be antidyslipidemic which has the effect of lowering triglyceride levels. This study aimed to explore the effect of Cnidoscolus aconitifolius leaf extract on triglyceride levels and body weight of Wistar rats with metabolic syndrome.Methods: This randomized controlled trial with a pre- and posttest design was conducted in 2021 at the Center for Food and Nutrition Studies, Yogyakarta, Indonesia. Male Wistar rats were subjected into metabolic syndrome state with a high-fat and high-fructose diet (HFHFD) for 21 days, then injected with Streptozotocin (STZ, 45 mg/kg) and Nicotinamide (NA, 110 mg/kg), and designated as positive control group. The intervention group was given 150 mg/kg, 300 mg/kg, and 450 mg/kg dose of leaf extract for 28 days. Triglyceride, glucose, high-density lipoprotein or HDL, and cholesterol were measured before and after intervention, using serum samples taken from the retro-orbital vein and analyzed using an enzymatic colorimetric method. The Wistar weight was measured every week. Data was analyzed by paired T-test and One-way ANOVA with Post-hoc Bonferroni and Games-Howell.Results: There was a significant decrease in triglyceride levels after the intervention (p< 0.005). Interestingly, there was also a significant increase in weight gain in all groups after the intervention (p=0.000), both were dose dependent.Conclusion: Cnidoscolus aconitifolius leaf extract is significantly lowering triglyceride levels in the Wistar rats model. In addition, weight gain has also been observed after intervention. Clinical studies are needed to further explore the potential of Cnidoscolus aconitifolius leaves as anti-dyslipidemia.
EFFECT OF BLACK GLUTINOUS TAPE BEVERAGE ON MALONDIALDEHYDE IN METABOLIC SYNDROME RATS Khoirunnisa, Rahmi; Putranto, Wachid; Nurwati, Ida
Media Penelitian dan Pengembangan Kesehatan Vol. 33 No. 4 (2023): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v33i4.1719

Abstract

Sindrom Metabolik (SM) dikenal sebagai sindrom resistensi insulin, juga dikenal sebagai faktor risiko DMT2. Diperlukan kombinasi perubahan gaya hidup dan pengobatan dalam penanganan SM. Sari tape ketan hitam (BGTB) sebagai pangan lokal mengandung tinggi kandungan antosianin sebagai sumber antioksidan dan Lactobacillus spp., yang berpotensi sebagai sumber probiotik yang dapat memperbaiki stres oksidatif pada pasien SM. Studi ini dirancang untuk mengevaluasi efek BGTB dalam menangani stres oksidatif, dengan melakukan pengukuran pada kadar MDA. Sebanyak 30 tikus Sprague Dawley digunakan dalam penelitian ini dan mereka dibagi menjadi lima kelompok. Kelompok normal (KN) akan diberikan diet standar, sedangkan keempat kelompok akan diberikan high-fat diet (HFD) selama 2 minggu dan kemudian diinduksi menggunakan Streptozotocin (STZ) dan Nicotinamide (NA); kontrol negatif (KN) akan diberikan standar diet; kontrol positif (KP) akan diberikan metformin 9 mg; kelompok perlakuan 1 (P1) dan perlakuan 2 (P2) akan diberikan BGTB sebanyak 0,9 ml 200 gr-1 BB dan 1,8 ml 200 gr-1 BB, diberikan selama 28 hari. Hasil menunjukan adanya perbedaan sginifikan (p=0.000) pada kadar malondialdehid, dengan perbandingan tertinggi pada kelompok P2. Penelitian ini menunjukkan BGTB dapat menjadi makanan fungsional dan berpotensi menjadi sumber probiotik untuk pasien SM.
A scoping review : Potential nutraceutical values of bioactive compounds and antioxidant activity in durian seed – An exotic tropical plant Aisyah, Siti; Harioputro, Dhani Redhono; Nurwati, Ida
World Nutrition Journal Vol. 8 No. i2 (2025): Volume 08 Issue 2, February 2025
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V08.i2.0001

Abstract

Background: Durian is a tropical fruit with a unique flavour and intense aroma. All parts of durian are reported to have many health benefits, especially the seeds. The seeds are known to have higher antioxidant activity and phytochemical compound than the pulp. Durian seeds are food waste that has the potential to be reused in the food and health industry. Objective: This article provides information on the presence of bioactive compounds, antioxidant activity, and the potential use of durian seeds as therapeutic agents. Methods: The study used a scoping review with four databases: Google Scholar, PubMed, DOAJ, and ScienceDirect. Scoping is needed to complete the article, summarize scientific data, and as a future reference regarding the nutraceutical potential of durian seeds. Results: A total of 6 articles were reviewed based on the screening results. The bioactive compounds found in these articles are phenolics, flavonoids, α-tocopherol, terpenoids, saponins, anthraquinones, and several flavonoid classes such as catechin, rutin, isoquercitrin, quercitrin. Total phenolic content (TPC) and antioxidant activity were highest in the Chanee durian seed cultivar compared to the Monthong type and various other cultivars from several countries. Conclusion: Durian seeds as food waste seem to have potential as a nutraceutical. Known as food waste that is rarely utilized, based on several studies, durian seeds have several benefits, one of which is to overcome various diseases. Further research needs to be done to prove that durian seeds can be helpful in the food industry as well as in pharmaceutical and cosmetic applications.
Co-Authors A. Guntur Hermawan Ambar Mudigdo Anik Lestari Asrial, An A. Baihaqy, Fathu Thaariq Betty Saptiwi Betty Saptiwi Betty Saptiwi Brian Wasita Christanto, Antonius Danus Hermawan Danus Hermawan Dicky Maulana Lazuardi Diding H P Diding Heri Prasetyo Diding Heri Prasetyo Dono Indarto Dyah Rahmawatie Ratna Budi Utami Dyah Ratna Budiani Dyah Ratna Budiani Dyah Ratna Budiani Eriana Melinawati Eric Edwin Yuliantara Eti Poncorini Pamungkasari Fahmi, Muhammad Izzul Widad Gresmita Rindi Winarti Hadi, Cahyono Harioputro, Dhani Redhono Hermawan, Danus Ika Tristanti Jarot Subandono Jarot Subandono Jarot Subandono Khoirunnisa, Rahmi Lazuardi, Dicky Maulana Martini Martini Martini Martini Martini Martini Muthmainah Muthmainah Muthmainah Muthmainah Muthmainah Muthmainah Muthmainah Muthmainah Mutmainah Mutmainah Nabila Aushaf Prasetyo Nafisa, Putri Amalina Nanang Wiyono Noni Kartika Sari Nugroho, Anung N. Nur Hafidha Hikmayani Nur Hafidha Hikmayani Nutria Widya Purna Anggraini Octavia, Dhamayanti Eka Pamungkasari, Eti P. Paramasari Dirgahayu Prihandjojo Andri Putranto Pudjiastuti, Anggit Putranto, R. Prihandjojo Andri Putranto, Wachid Reviono Reviono Risya Cilmiaty A. R. Risya Cilmiaty AR Risya Cilmiaty, Risya Rosyida, Rufaida Sari, Noni Kartika Sarsanti, Arifa Sherina Noor Sarsono Sarsono Sarsono Sarsono Sarsono Sarsono Sarsono Sarsono Selfi Handayani Selfi Handayani Selfi Handayani Selfi Handayani Setiamika, Made Setianto, Budi Y. Sigit Setyawan Sineri, Dessy Ikasartika Siti Aisyah Siti Marufah Soetrisno Soetrisno Sri Hartati Hadinoto Sri Haryati Sri Sulistyowati Sumardiyono Sumardiyono Sumardiyono, S Uki Retno Budihastuti Vitri Widyaningsih Wahyu Anjas Sari Wesliaprilius, Todung Antony Wiyono, Nanang Yarso, Kristanto Y. yoseph Indrayanto Yudhani, Ratih Dewi Yulia Sari Yulyanti, Yulyanti