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All Journal HAYATI Journal of Biosciences Jurnal Ilmu Pertanian Indonesia Jurnal Akuakultur Indonesia ACTA VETERINARIA INDONESIANA Hemera Zoa Jurnal Sain Veteriner Buletin Peternakan Jurnal Veteriner JURNAL KIMIA SAINS DAN APLIKASI Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) Biodidaktika : Jurnal Biologi dan Pembelajarannya Jurnal Penelitian Pendidikan IPA (JPPIPA) Indonesian Aquaculture Journal Jurnal Riset Akuakultur Jurnal Medik Veteriner ARSHI Veterinary Letters Berkala Penelitian Hayati Jurnal Kedokteran Hewan Current Biomedicine Jurnal Medika Veterinaria
Agustin Indrawati
Bagian Mikrobiologi Medik, Departemen Ilmu Penyakit Hewan Dan Kesmavet, Fakultas Kedokteran Hewan Institut Pertanian Bogor
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Education Engineering Environmental Science Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Physics Public Health Social Sciences Veterinary Other

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Evaluasi antidiare infus daun jambu biji pada tikus pediatrik menggunakan model transit usus Hendry, Altaff; Yan, Teo Qin; Andre, Daniel Latief; Rahman, Muhammad Luthfi; Rudramurti, Win Satya; Permana, Nadine Hanifa; Utami, Dian Maulia; Pristihadi, Diah Nugrahani; Indrawati, Agustin
ARSHI Veterinary Letters Vol. 9 No. 4 (2025): ARSHI Veterinary Letters - November 2025
Publisher : School of Veterinary Medicine and Biomedical Sciences, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avl.9.4.119-120

Abstract

Diare merupakan gangguan gastrointestinal utama pada anak-anak dan masih menjadi penyebab kematian yang signifikan, terutama pada balita. Daun jambu biji (Psidium guajava L.) telah lama digunakan dalam pengobatan tradisional sebagai obat antidiare. Penelitian ini bertujuan untuk menentukan dosis efektif infusa daun jambu biji pada tikus yang disapih menggunakan metode transit intestinal. Tiga puluh tikus sehat secara acak dibagi menjadi enam kelompok: kontrol negatif (air suling), kontrol positif (atropin sulfat 2,5 mg/kg BB), dan empat kelompok perlakuan yang menerima infusa daun jambu biji dengan dosis 100, 200, 400, dan 800 mg/kg BB. Di antara kelompok perlakuan, dosis 200 mg/kg BB menghasilkan penurunan transit intestinal terbesar. Namun, tidak ada perbedaan yang signifikan secara statistik yang diamati antara kelompok perlakuan dan kontrol negatif. Hasil ini menunjukkan bahwa dalam rentang dosis yang diperiksa, infusa daun jambu biji tidak menunjukkan efek antidiare yang signifikan pada model tikus pediatrik.
Detection of quinolone antibiotic resistance genes in Escherichia coli isolated from dairy cattle feces Raihan, Muhammad Ammar; Elsharkawy, Sara; Indrawati, Agustin; Latif, Hadri
Current Biomedicine Vol. 4 No. 1 (2026): January
Publisher : School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/currbiomed.4.1.1

Abstract

Background Livestock raised in densely populated areas can serve as reservoirs for bacteria such as Escherichia coli, which may harbor antibiotic resistance genes that threaten both animal and human health. Objective This study aimed to identify and characterize quinolone resistance genes in E. coli isolated from dairy cattle feces. Methods Fifteen E. coli isolates were obtained from 15 dairy farms located in Kebon Pedes, Bogor, West Java. Genotypic detection of quinolone resistance genes was conducted using DNA sequencing on the MinION platform. Results All E. coli isolates (100%) carried at least one quinolone resistance gene. Of these, ten isolates (67%) contained a single resistance gene, while five isolates (33%) possessed two genes. The qnrS1_1 gene was identified in all isolates and represented the predominant genotype, whereas the qnrVC4_1 gene was found in five isolates (33%), mostly co-occurring with qnrS1_1. Both genes are plasmid-mediated and categorized as plasmid-mediated quinolone resistance (PMQR) genes. Conclusion The detection of qnrS1_1 and qnrVC4_1 genes in E. coli isolated from dairy cattle feces indicates that livestock manure may act as a reservoir for quinolone resistance genes, contributing to their persistence and potential spread within farm environments.
Co-Authors . Darniati Aditya Primawidyawan Afifah Nurhasanah Afiff , Usamah agrita, tri wera Agus Sjahrurachman Ambar Retnowati Ambar Retnowati Andre, Daniel Latief ANGELA MARIANA LUSIASTUTI ANGELA MARIANA LUSIASTUTI Angela Mariana Lusiastuti Apris Beniawan Ardiana Ardiana Arum, Diah Sekar Bayu Febram Prasetyo Betty Ernawati Damiana Rita Ekastuti Darniati D, Darniati Denny Widaya Lukman Destri Prameswari, Alvira Diah Nugrahani Pristihadi Diah Sekar Arum Dwi Endrawati Edi Purwanto Elmanaviean Elsharkawy, Sara Eni Kusumaningtyas Erdina Pangestika Erin Kurnianingtyas Fachriyan H Pasaribu Fachriyan Hasmi Pasaribu Fachriyan Hasmi Pasaribu Fachriyan Hasmi Pasaribu Fachriyan Hasmi Pasaribu Fachriyan Hasmi Pasaribu Fadlilah, Ulfi Nurul Fera Ibrabim Guntari Titik Mulyani Hadri Latif Hamdika Yenri Handayani Halik Handina Rakhmawati HELGA SEEGER Hendarko, Sriani Hendry, Altaff Hermana, Nabila Swarna Puspa Herwin Pisestiyani I Wayan T. Wibawan I wayan Teguh Wibawan Idwan Sudirman Ita Krissanti Jefri Naldi Jeni Maharani Julia Rosmaya Riasari Kuntum Khoirani Kurnia Tiara Aulia Lee Xia Meen Leila Nur Aziah Leila Nur Azizah Lila Gardenia Maharani, Jeni Mangaraja Pidoli Tampubolon Mardiastuti Mardiastuti MICHAEL ZSCHÖCK Mira Mawardi Mirnawati Bachrun Sudarwanto Mirnawati Sudarwanto Muh Ramadhan Nabila Swarna Puspa Hermana Nabila Swarna Puspa Hermana Nafiqoh, Nunak Naldi, Jefri Nauval Firdana, Chorrysa Navasuriya Radha Krisnan Nazmi Zahir B. Mohd Zaini Ni Luh Putu Ika Mayasari Ni Luh Putu Ika Mayasari Nining Arini Novita, Hessy Nurhasanah, Afifah Nurul Fadillah Nurul fadillah, Nurul Oktaviani, Dian Okti Nadia Poetri Penataseputro, Tanjung Permana, Nadine Hanifa Pratitis S Wibowo Pratitis S Wibowo Rahman, Muhammad Luthfi Rahmat Hidayat Rahmat Hidayat Raihan, Muhammad Ammar Ramadhaniah, Vetty Reinilda Alwina Retno D. Soejoedono Retno Damajanti Retno Damayanti Soejoedono Rifky Danial Rifky Rizkiantino Risqika Aqla Velayati Romsyah Maryam Rudramurti, Win Satya Rukmi, M.G. Isworo Ryan Septa Kurnia Safika S, Safika Sapto Andriyono Sartika Juwita Seruni Agistiana Setiadi Setiadi Siti Fatimah Siti Gusti Ningrum, Siti Gusti Siti Nur Jannah Sucitya Purnama Suhartila Suhartila Suherman . Surachmi Setiyaningsih Susan M Noor Susan M Noor Susanti, Wiwik Susanto Nugroho Syahidah, Dewi Teguh Budipitojo Titiek Sunartatie Titis Wulandari Tri Wiyoko Trioso Purnawarman Triwardhani Cahyaningsih Ulfi Nurul Fadlilah Uni Purwaningsih Uni Purwaningsih Upik Kesumawati Hadi Usama Affif Usamah Afif Utami, Dian Maulia Uus Saepuloh Velayati, Risqika Aqla Wattiheluw, Muhammad Subhan Yan Evan Yan, Teo Qin Yenri, Hamdika Yuda Heru Fibrianto