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All Journal BIOLINK (Jurnal Biologi Lingkungan, Industri, Kesehatan) JMM (Jurnal Masyarakat Mandiri) Pharmasipha Martabe : Jurnal Pengabdian Kepada Masyarakat Jambura Journal of Health Sciences and Research Jambura Journal of Chemistry Journal Syifa Sciences and Clinical Research (JSSCR) Jurnal Sibermas (Sinergi Pemberdayaan Masyarakat) Indonesian Journal of Pharmaceutical Education Indonesian Community Journal Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Jurnal Multidisipliner Kapalamada Jurnal Farmasi Teknologi Sediaan dan Kosmetika (JFTSK) Journal of Community and Clinical Pharmacy Journal of Pharmacology and Natural Products Jurnal Riset dan Pengabdian Interdisipliner
Mahdalena Sy Pakaya
UNIVERSITAS NEGERI GORONTALO
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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ANTIOXIDANT ACTIVITY EVALUATION OF CATFISH (CLARIAS SP.) COLLAGEN EXTRACT USING DPPH AND ABTS METHODS Hiola, Faramita; Zuriati Uno, Wiwit; Sy. Pakaya, Mahdalena; Hutuba, Ariani
Jurnal Multidisipliner Kapalamada Vol. 4 No. 04 (2025): JURNAL MULTIDISIPLINER KAPALAMADA
Publisher : Pusat Studi Ekonomi, Publikasi Ilmiah dan Pengembangan SDM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62668/kapalamada.v4i04.1964

Abstract

This study aimed to evaluate the antioxidant activity of collagen extracted from catfish (Clarias sp.) using DPPH and ABTS assays. The research procedures included sample preparation, collagen extraction using an acid-based method, and antioxidant analysis at concentrations ranging from 20–100 ppm. The degree of hydrolysis (DH) was measured to determine the effectiveness of Alkalase in producing bioactive peptides. The results showed that higher enzyme concentrations led to increased DH, with the highest value of 62.42% obtained at 3% Alkalase. Antioxidant activity increased with sample concentration, with maximum inhibition values of 78.57% (DPPH) and 85.00% (ABTS) at 100 ppm. The ABTS assay exhibited higher sensitivity than DPPH. These findings indicate that catfish collagen has strong potential as a safe and natural antioxidant source suitable for further development in food, pharmaceutical, and cosmetic applications.
Analisis Penerapan Metode ATC/DDD dan DU90% Dalam Penggunaan Antibiotik Pada Pasien Rawat Inap Rumah Sakit Stella Maris Makassar Arsyad, Rival Al-fazri; Pakaya, Mahdalena Sy.; Paneo, Mohamad Aprianto; Rasdianah, Nur; Madania, Madania
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Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/jrpi.v3i1.36531

Abstract

The antimicrobial resistance (AMR) crisis poses a serious threat to global health, making the rational use of antibiotics a priority within Antimicrobial Stewardship (AMS) programs. This study aims to evaluate the patterns and quantity of antibiotic use among inpatient populations at Stella Maris Hospital Makassar using the Anatomical Therapeutic Chemical (ATC) classification, Defined Daily Dose (DDD), and Drug Utilization (DU) 90% methods. This research employed a retrospective descriptive observational design using medical record data of patients who received antibiotic therapy from October to December 2024. The analysis was conducted by calculating DDD per 100 patient-days and identifying antibiotics contributing to 90% of total use. The results showed eight types of antibiotics were utilized. The three antibiotics with the highest DDD/100 patient-days were Cefuroxime (13.43), Ceftriaxone (11.8), and Cefotiam (10), which, together with Moxifloxacin, were included in the DU 90% segment. The predominance of second-generation cephalosporins—particularly among diagnoses such as unspecified fever, bronchiectasis, typhoid, and bronchitis—indicates a tendency toward broad-spectrum empirical therapy in chronic pulmonary conditions such as COPD and bronchiectasis. In conclusion, antibiotic use at Stella Maris Hospital Makassar is dominated by the cephalosporin class, highlighting the need for ongoing evaluation and strengthened implementation of AMS programs to optimize antibiotic therapy, improve treatment effectiveness, and reduce the risk of increasing antimicrobial resistance at the hospital level.
Pemberdayaan Masyarakat Desa Buti Melalui Inovasi Produk Minuman Fungsional dari pangan Lokal Menuju Desa Bebas Stunting dan Mandiri Gizi Uno, Wiwit Zuriati; Pakaya, Mahdalena Sy; Hunawa, Rachmawaty D
Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Vol 5, No 1 (2026)
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/phar.soc.v5i1.34132

Abstract

Stunting merupakan masalah kesehatan masyarakat yang masih tinggi di Indonesia, termasuk di Desa Buti, Gorontalo, yang disebabkan oleh kekurangan gizi kronis pada 1000 Hari Pertama Kehidupan (HPK). Rendahnya literasi gizi, terbatasnya pemanfaatan pangan lokal, serta minimnya peluang usaha menjadi faktor utama penyebab. Metode yang digunakan pada Program Kuliah Kerja Nyata Profesi Kesehatan (KKN-PK) dilaksanakan melalui tiga tahap: (1) persiapan (survei awal, pendataan balita stunting, rekrutmen peserta), (2) pelaksanaan (edukasi gizi, pelatihan pembuatan minuman herbal berbahan jagung, jahe merah, sereh, dan lengkuas, serta uji organoleptik), dan (3) keberlanjutan (pendampingan kader PKK dan posyandu, distribusi leaflet, monitoring, serta publikasi hasil kegiatan). Hasil yang diperoleh dari Program ini meningkatkan pengetahuan gizi masyarakat secara signifikan (skor post-test 82% dibandingkan pre-test 55%). Selain itu, tercipta prototipe minuman herbal fungsional yang disukai masyarakat, serta peningkatan kapasitas kader PKK dan posyandu sebagai agen edukasi gizi. Masyarakat juga memperoleh keterampilan baru dalam pengolahan pangan lokal. Kesimpulan: Program berhasil meningkatkan literasi gizi, mendorong pemanfaatan pangan lokal, serta membuka peluang usaha berbasis komunitas. Keberlanjutan program diharapkan melalui penguatan kelompok usaha desa, integrasi dengan kegiatan posyandu, serta dukungan pemerintah desa, sehingga Desa Buti dapat mewujudkan “Desa Bebas Stunting dan Mandiri Gizi.
Co-Authors A. Mu’thi Andy Suryadi Abas, Siti Nur Rahmatiya Abdullah, Rahayu Anatasya Putri Ade Ari Puspitadewi Akuba, Juliyanti Ali, Muthiah Rahmah alkatiri, ahmad alkatiri AM Andy Suryadi AM. Andy Suryadi Andi Makkulawu Ar’syifa Wijaya, Hudan Ariani H. Hutuba Arista Idris, Pinkan Arona Salama Arsyad, Rival Al-fazri Basri, Rakhmadana Fitraeni Datukramat, Hendrawan Dwikarunia Dewa Ayu Puspita Dewi Rahmawaty Moo djuarno, endah nurrohwinta Djuwarno, Endah Nurrowinta Dr. Apt. Hamsidar Hasan S.Si.,M.Si dwi pratiwi, susi Endah Nurrohwinta Djuwarno Fajar Dwi Agung Fatimah Azzahra Fazril Pakaya, Mohamad Fika Nuzul Ramadhani Fitriah Ayu Magfirah Yunus Grasela Mbae Hamsidar Hasan Hamsidar Hasan Hartati Hartati Hiola, Faramita Hiola, Paramita Hunawa, Rachmawaty Dirham Hutuba, Ariani I Made Hariadi Wijaya Ibrahim, Aliya Ibrahim Ibrahim, Annisa Humairah Jihan Astuti Kai Julianty Akuba Kongkolu, Sitty Rahma Hutami kopman, aldafarista La Ode Aman LATIF, MULTIANI S Latif, Multiani S. Liberto, Frith F. Madania Madania, Madania Madania, Madania Magfirah Nur Cahyani Makkulawu, Andi Manno, Mohamad Reski Maspeke, Khofifa Nurul Magfira Moh. Adam Mustapa Mohamad Adam Mustapa Mohamad Aprianto Paneo Moo, Faradila Ratu Cindana Muhammad Taupik Muhammad Taupik Mustapa, Moh. Adam Muthiah Rahmah Ali Nazwah Buana Putri Kalangi Niluh Sri Purnama Nur Ain Thomas Nur Rasdianah Nurdiandra Jahja pakaya, Handriansyah Pakaya, Meri Isriani Papeo, Dizky Ramadani Papeo, Dizky Ramadani Putri Papeo, Pirdawati priliya wati d.as'ali Prisca S. Wicita Puluhulawa, Lisa Efriani Qarlan Pratama, Mohammad Rahmawati Hunawa Ramly Abudi Robert Tungadi S. Latif, Multiani Santi Santi Selvi Marcellia Suryadi, A. Muthi Andi Suryadi,, A. Mu'thi Andy Teti Sutriyati Tuloli Thamrin, Rahmulia Tolulu, Sri Noviani umar, linsih Widy Susanti Abdulkadir Widy Susanti Abdulkadir Widysusanti Abdulkadir Wiwit Zuriati Uno Yayah Rachmatiyah Zahra Zakia, Wavika Zuriati Uno, Wiwit