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Evaluasi Penggunaan Obat Anti diabetes Oral pada Pasien Diabetes Melitus Tipe II di Instalasi Rawat Jalan Rumah Sakit Azizah Metro Pamungkas, Pratiwi May; Ginaris , Rifkarosita Putri; Nurrahman, Alfina
PHARMADEMICA : Jurnal Kefarmasian dan Gizi Vol 5 No 1 (2025): April - September
Publisher : LPPM-KI - POLTEKKES PIM (Formerly AKAFARMA-AKFAR PIM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54445/pharmademica.v5i1.90

Abstract

Diabetes mellitus (DM) is a chronic metabolic disease characterized by elevated blood glucose levels (hyperglycemia). This condition arises due to impaired insulin production, the body's inability to effectively utilize insulin, or a combination of both. The rational use of antidiabetic drugs is crucial in managing blood glucose levels in diabetic patients. This study aimed to evaluate the use of oral antidiabetic drugs in patients with type 2 DM at the outpatient clinic of Azizah Metro Hospital. The research employed a descriptive design with retrospective data collection, using patient medical records from October to December 2024 as the data source. The sampling technique was total sampling, with a total of 80 patients as respondents. The majority of patients were female (77.5%), and the most prevalent age group was 56–65 years (48.75%). Most patients were on monotherapy (68.75%), with glimepiride being the most frequently prescribed drug (33.75%). The evaluation results showed that all patients (100%) met the criteria for appropriate drug use based on patient condition, indication, drug type, and dosage. In conclusion, the use of oral antidiabetic drugs in type 2 DM outpatients at Azizah Metro Hospital during the period of October–December 2024 has met the principles of rational therapy with an accuracy rate of 100%.
Evaluasi Perencanaan dan Pengadaan Obat Menggunakan Analisis ABC–VEN di Rumah Sakit Mardi Waluyo Metro Sitanggang, Andrianus Bilhot; Ginaris, Rifkarosita Putri; Nurahman, Alfina
PHARMADEMICA : Jurnal Kefarmasian dan Gizi Vol 5 No 1 (2025): April - September
Publisher : LPPM-KI - POLTEKKES PIM (Formerly AKAFARMA-AKFAR PIM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54445/pharmademica.v5i1.92

Abstract

The unguaranteed availability of medicines in hospitals can reduce the quality of healthcare services, hinder therapeutic processes, and increase the risk of adverse events for patients. Therefore, an effective medicine procurement planning strategy is needed to optimally meet clinical needs. This study aims to analyze drug procurement planning at the Pharmacy Installation of Mardi Waluyo Hospital Metro using the ABC-VEN method. The analysis was conducted on 453 drug items planned by the hospital. The results showed that the main category (U) dominated with 245 items (54.08%), the priority category (P) consisted of 137 items (30.24%), and the additional category (T) consisted of 71 items (15.68%). Medicines with the highest usage values were in group A, indicating the need for strict monitoring to prevent stockouts. However, groups B and C drugs also require attention since some are vital medicines despite their relatively low usage levels. These findings highlight the importance of applying the ABC-VEN method to support efficiency in drug management while ensuring continuity of hospital services.
Memfasilitasi Pelajar KIR (Karya Ilmiah Remaja) Biologi Dengan Kajian Isolasi dan Identifikasi Bakteri Escherichia coli Dari Sampel Kotoran Hewan Ternak Sepanjang SMAN 5 Cilegon Di Laboratorium UPTD Banten Rezaldi, Firman; Cahyono, Andri Tri; Wati, Dyah Rohma; Ginaris, Rifkarosita Putri; Utami, Arti Wahyu; Wijayanti, Fitria Eka Resti; Purbanova, Reni; Nabilla, Jihan; Nurfadhillah, Dea; Faizah, Na’imatul Retno; Nurrahman, Alfina; Oentari, Octavina Dyah; Pramono, Edi; Yudianto, Tri; Sari, Sinta Wisma; Widyaningsih, Ragil; Kustyarini, Farida; Fatchani, Sathi
Jurnal Pengabdian dan Pengembangan Masyarakat Indonesia Vol. 3 No. 2 (2024)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jppmi.v3i2.275

Abstract

Cemaran bakteri Escherichia .coli merupakan salah satu ancaman bagi setiap daya tahan tubuh makhluk hidup. Menurunnya daya tahan tubuh makhluk hidup disebabkan oleh minimnya kualitas kesehatan yang bersumber pada produk makanan yang tercemar, produk obat yang tercemar, produk kosmetik yang tercemar hingga lingkungan sekitar yang sering tercemar berat. Lingkungan sekitar yang sering tercemar cukup tinggi dan berpeluang besar oleh adanya serangan bakteri Escherichia. coli terdiri atas produk hasil pertanian maupun peternakan yang banyak menimbulkan diare bagi masyarakat yang tidak memiliki imunitas yang kurang stabil. Aktivitas peternakan menjadi salah satu permasalahan dalam mencemari lingkungan adalah kotoran hewan ternak disepanjang SMAN 5 Cilegon. Kotoran hewan ternak disepanjang SMAN 5 Cilegon terdiri dari kotoran hewan ternak ayam, kambing, dan kerbau. Ketiga kotoran hewan ternak tersebut tentunya mengandung bakteri Escherichia coli yang merupakan salah satu bakteri gram negatif penyebab kejadian luar biasa atau KLB yang perlu diberikan suatu pemaparan bagi siswa maupun siswi SMAN 5 Cilegon yang pro aktif dalam mengikuti Karya Ilmiah Remaja (KIR) bidang Biologi untuk meningktakan pengetahuan dan wawasan mengenai keberadaan bakteri E coli yang terdapat di SMAN 5 Cilegon dari tiga kotoran hewan ternak. Pengabdian kepada masyarakat ini adalah bertujuan untuk memfasilitasi siswa maupun siswi yang terlibat dalam kegiatan KIR Biologi untuk memperoleh cara isolasi dan identifikasi bakteri Escherichia coli yang terdapat di sepanjang SMAN 5 Cilegon Banten. Pengabdian kepada masyarakat bekerja sama dengan Laboratorium UPTD Pengujian dan Penerapan Mutu Hasil Perikanan (PPMHP) Provinsi Banten dengan metode yang berlaku. Tahapan kegiatan ini meliputi survey, pra plaksanaan, pelaksanaan, dan evaluasi. responden yang telah teruji berdasarkan hasil pre test mengenai wawasan dan pengetahuan isolasi dan identifikasi bakteri E. coli yang diambil dari tiga sampel kotoran hewan ternak sepanjang SMAN 5 Cilegon. Siswa siswi yang paham sebesar 23% dan 77% adalah komposisi persentase siswa dan siswi yang belum paham mengenai materi isolasi bakteri E. coli dari ketiga sampel kotoran hewan ternak. Sampel kotoran hewan ternak yang terdapat disepanjang SMAN 5 Cilegon seperti kerbau, kambing, dan ayam telah terbukti mengandung bakteri Escherichia coli
FORMULASI SEDIAAN ODOL KOMBUCHA BUNGA TELANG SEBAGAI PRODUK BIOTEKNOLOGI FARMASI DAN ANTIMIKROBA (Staphylococcus aureus, Streptococcus mutan, Candida albicans).Telang flower kombucha has been widely studied as a probiotic drink that can boost the immune s Rezaldi, Firman; Yuliana Kolo; Ratna Fitry Yenny; Vevi Maritha; Novi Ayuwardani; Andri Tri Cahyono; Fitria Eka Resti Wijayanti; Rifkarosita Putri Ginaris; Reni Purbanova
PHARMACIA Vol. 2 No. 2 (2024): Pharmacy
Publisher : Program Studi Farmasi Universitas Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Telang flower kombucha has been widely studied as a probiotic drink that can boost the immune system which in recent research has various pharmacological activities as a source of antimicrobials, especially in health problems related to dental disease. Previous studies and this is still a renewable research has found that mouthwash formulations and preparations made from an active ingredient of seagrass kombucha fermented solution have been shown to be able to inhibit the growth of Staphylococcus aureus, Candida albicans, and Streptococcus mutans. This study aims to make toothpaste formulations and preparations with an active ingredient of telang flower kombucha fermented solution as a pharmaceutical biotechnology product designed to inhibit the growth of Staphylococcus aureus and mutant Streptococcus bacteria as well as pathogenic fungi in the form of Candida albicans species. This type of research is a laboratory experiment in which we make a toothpaste base without the active substance as a negative control. Provide toothpaste that is sold in the market as a positive control. Make formulations and preparations of toothpaste with active ingredients from the fermented butterfly pea flower kombucha solution which includes concentrations of 20%, 30% and 40%. Data analysis was used through one way ANOVA where in the results of the study each preparation had a P value <0.05, so that further tests could be carried out through post hoc analysis. eggplant at a concentration of 40% was significantly different from 20% and 30% as a pharmaceutical biotechnology product in inhibiting the growth of the three test microbes and the results of this study it can be concluded that the formulation and preparation of toothpaste made from the active ingredient of butterfly pea flower kombucha fermentation solution is the best treatment as an antimicrobial and pharmaceutical biotechnology products.
SOSIALISASI MENGENAI POTENSI PRODUK BIOTEKNOLOGI FARMASI BERUPA FORMULASI DAN SEDIAAN SPRAY KOMBUCHA BUNGA TELANG DAN BIOTEKNOLOGI PERTANIAN BERUPA PUPUK CAIR ORGANIK DARI LIMBAH FERMENTASI KOMBUCHA BUNGA TELANG KEPADA PETANI HORTIKULTURA K.P PEKUNCEN Rezaldi, Firman; Utami, Arti Wahyu; Sari, Sinta Wisma; Faizah, Nai’matul Retno; Wati, Dyah Rohma; Resti Wijayanti, Fitria Eka; Ginaris, Rifkarosita Putri; Purbanova, Reni; Sugiono, Sugiono; Saifullah, Ipul; Rohmatulloh, Rizal; Kurniawan, Maskun; Munir, Misbakhul; Mu'jijah, Mu'jijah; Sasmita, Heny; Somantri, Ucu Wandi
PARADIGMA PENGABDIAN Vol 1 No 1 (2024): Edisi : November
Publisher : Fakultas Keguruan dan Ilmu Pendidikan Universitas Abdurachman Saleh Situbondo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36841/paradigma.v1i1.5270

Abstract

Horticultural commodity crops are commodities that have high selling value and have properties as functional food and pharmaceutical ingredients. So the majority of horticultural farmers often prioritize meeting market needs. Obstacles that occur in the field are decreasing quality and quantity due to pest and disease attacks as well as excessive use of chemical-based fertilizers. The aim that can be offered in this community service activity is to provide education about the potential of butterfly pea flower kombucha, apart from being used as a functional food, it can also be used as a natural antibiotic without other additives as an antifungal pathogen from horticultural commodity plants as well as providing education about the potential of butterfly pea flower kombucha as a raw material for organic liquid fertilizer to support the growth of horticultural commodity plants which has been proven by various research results. by providing an explanation of the basics of butterfly pea flower kombucha fermentation which is useful as a probiotic drink to enhance the immune system in general which has a high potential for being a functional food, pharmaceutical/medicinal or cosmetic, an ingredient in organic liquid fertilizer preparations, and a natural antibiotic for fungal pathogens of horticultural plants. Horticultural farmers from Pekuncen village learned about the potential of butterfly pea flower kombucha with a percentage of 100% after the presentation of the material.
Antioxidant Lotion Formulation with a Combination of Ethanol Extracts of Black Soybean and Pigeon Pea Rekha Aulia Istikhomah; Rifkarosita Putri Ginaris; Alfina Nurrahman
Ar-Rasyid: Jurnal Publikasi Penelitian Ilmiah Vol. 1 No. 5 (2025): Ar-Rasyid: Jurnal Publikasi Penelitian Ilmiah (Bulan November 2025)
Publisher : PT. Saha Kreasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64788/ar-rasyid.v1i5.45

Abstract

Indonesia’s tropical climate with high sun exposure increases the risk of oxidative stress on the skin due to free radicals. Synthetic antioxidants in skincare products are proven effective but may cause long-term side effects. Natural ingredients offer a safer and more promising alternative. This study aimed to formulate an antioxidant lotion using ethanol extracts of black soybean and pigeon pea. Extraction was carried out by maceration using 70% ethanol as solvent. The extracts were formulated into five lotion formulas, consisting of three extract combinations, one positive control, and one negative control. Evaluation included antioxidant activity using the DPPH method and physical stability tests. Formula 3, containing 11,31% black soybean extract and 3,75% pigeon pea extract, shows the highest antioxidant activity with a strong category (IC₅₀ = 73,5 µg/mL). All formulas show good physical stability during 21 days of storage and form oil-in-water emulsions. The combination of black soybean and pigeon pea extracts demonstrates strong antioxidant potential with good formulation stability and is suitable for development in natural cosmetic products.
FORMULATION AND EVALUATION OF THE PHYSICAL QUALITY OF NIACINAMIDE GEL PREPARATIONS USING PVP AS A GELLING AGENT Zulananta, Shohihunnatiq; Ginaris, Rifkarosita Putri; Nurrahman, Alfina
JURNAL RISET KESEHATAN POLTEKKES DEPKES BANDUNG, Online ISSN 2579-8103 Vol 17 No 2 (2025): Jurnal Riset Kesehatan Poltekkes Depkes Bandung
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/juriskesbdg.v17i2.2883

Abstract

Niacinamide is the amide form of vitamin B3. Other forms of vitamin B3 include niacin (nicotinic acid). Polyvinylpyrrolidone (PVP) is a biodegradable and air-soluble polymer derived from the monomer N-vinylpyrrolidone. Gels are water-rich preparations and have better potential as topical drug delivery preparations compared to ointments because they are non-sticky, require low energy during formulation, are stable, and have aesthetic value. The purpose of this study was to evaluate the physical qualities of PVP-based niacinamide gel preparations based on physical quality parameters, including organoleptic test, ligninogenicity test, pH test, viscosity test, adhesiveness test, and spreading power test. The method used in this study was an experimental method carried out to determine the physical qualities of a good gel. The results of the study showed that the PVP-based niacinamide gel preparation produced had a thick gel texture, transparent color, odorless, homogeneous, an average pH value of 16.6, an average viscosity value of 2673.6 - 2179.6, an average spreadability value of 6.2 - 6.3, and an average adhesiveness value of 4.67 - 4.46. Based on these results, the PVP-based niacinamide gel preparation had physical quality that met the requirements according to good criteria.