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FORMULASI SEDIAAN ODOL KOMBUCHA BUNGA TELANG SEBAGAI PRODUK BIOTEKNOLOGI FARMASI DAN ANTIMIKROBA (Staphylococcus aureus, Streptococcus mutan, Candida albicans).Telang flower kombucha has been widely studied as a probiotic drink that can boost the immune s Firman Rezaldi; Yuliana Kolo; Ratna Fitry Yenny; Vevi Maritha; Novi Ayuwardani; Andri Tri Cahyono; Fitria Eka Resti Wijayanti; Rifkarosita Putri Ginaris; Reni Purbanova
PHARMACIA Vol. 2 No. 2 (2024): Pharmacy
Publisher : Program Studi Farmasi Universitas Mulia

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Abstract

Telang flower kombucha has been widely studied as a probiotic drink that can boost the immune system which in recent research has various pharmacological activities as a source of antimicrobials, especially in health problems related to dental disease. Previous studies and this is still a renewable research has found that mouthwash formulations and preparations made from an active ingredient of seagrass kombucha fermented solution have been shown to be able to inhibit the growth of Staphylococcus aureus, Candida albicans, and Streptococcus mutans. This study aims to make toothpaste formulations and preparations with an active ingredient of telang flower kombucha fermented solution as a pharmaceutical biotechnology product designed to inhibit the growth of Staphylococcus aureus and mutant Streptococcus bacteria as well as pathogenic fungi in the form of Candida albicans species. This type of research is a laboratory experiment in which we make a toothpaste base without the active substance as a negative control. Provide toothpaste that is sold in the market as a positive control. Make formulations and preparations of toothpaste with active ingredients from the fermented butterfly pea flower kombucha solution which includes concentrations of 20%, 30% and 40%. Data analysis was used through one way ANOVA where in the results of the study each preparation had a P value <0.05, so that further tests could be carried out through post hoc analysis. eggplant at a concentration of 40% was significantly different from 20% and 30% as a pharmaceutical biotechnology product in inhibiting the growth of the three test microbes and the results of this study it can be concluded that the formulation and preparation of toothpaste made from the active ingredient of butterfly pea flower kombucha fermentation solution is the best treatment as an antimicrobial and pharmaceutical biotechnology products.
Co-Authors Adelia, Kusza Afifa, Nadya Alfina Nurrahman Alfina Nurrahman Alfina Nurrahman Amalia Eka Putri Amalia, Risa Amelia Andriani, Deva Andri Tri Cahyono Andri Tri Cahyono Ani Florida Arif Santoso Arti Wahyu Utami Arti Wahyu Utami Arti Wahyu Utami Arti Wahyu Utami Aryadi, Anggi Bagus Setiawan, Irfan Bramantyo Cahyono, Andri Tri Cecep Sudrajat Damianus Boru, Rohot Dea Nurfadhillah Dea Nurfadhillah Desi Trisnawati Detria Wulandari Dwi Wahyuni Dyah Rohma Wati Edi Pramono Eman eman Erni Suminar Esa Aji Pratama Faizah, Nai’matul Retno Faizah, Na’imatul Retno Fatchani, Sathi Fatikha, Zulfania Shandra Fauzah, Na’imatul Retno Febi Astuti, Ravita Firman Rezaldi Fitria Eka Resti W. Fitria Eka Resti Wijayanti Fitria Eka Resti Wijayanti Fitria Eka Resti Wijayanti Gumilar, Roni Hariningsih, Yetti Heny Sasmita Indrayati, Lyna L. Ira Maya Irfan Bagus Setyawan Istikhomah, Rekha Aulia Iyan Sopyan Jihan Nabilla Jihan Nabilla Kurniawan, Maskun Kustyarini, Farida Lyna Lestari Indrayati M. Fariz Fadillah Misbakhul Munir Mu'jijah, Mu'jijah Muhammad Faizal Fathurrohim Mutiara Siti Nurfajriah Nabilla, Jihan Nai’matul Retno Faizah Na’imatul Retno Faizah Na’imatul Retno Fauzah Nova Seftiyanti Novi Ayuwardani Nurahman, Alfina Nurrahman, Alfina Octaviana Dyah Oentari Oentari, Octavina Dyah Pamungkas, Barolym Tri Pamungkas, Pratiwi May Pani Pratiwi, Reza Safinda Pujiastuti, Nanik Puput Setiawati Purbanova, Reni Putri, Amalia Eka Putri, Desvita Maharani R, Herowati Rahmad, Sukardi Sugeng Ratna Fitry Yenny Rekha Aulia Istikhomah Rekha Aulia Istikhomah Reni Purbanova Reni Purbanova Reni Purbanova Resti Wijayanti, Fitria Eka Rohmatulloh, Rizal Rohot Damianus sidauruk Sadida, El Santi Saifullah, Ipul Santoso, Blegoh Iwan Sari, Sinta Wisma Sasmita, Heny Sekar Wangi, Epi Setiawati, Puput Setyawan, Irfan Bagus Sinta Wisma Sari Sinta Wisma Sari Sitanggang, Andrianus Bilhot Sugiono Sugiono Sukardi Sugeng Rahmad Sukardi Sugeng Rahmad Sukardi Sugeng Rahmad TN Saifullah Sulaiman Tri Saptari Haryani Tri Yudianto Tri Yudianto Trisnawati, Desi Ucu Wandi Somantri Ucu Wandi Somantri Usman Setiawan Vevi Maritha W, Fitria Eka Resti Wardani, Arief Kusuma Widya Astri, Fani Widyaningsih, Ragil Wijayanti Wijayanti Wijayanti, Fitria Eka Resti Yanti, Jamilah Hamidi Yenny, Ratna Fitry Yudianto, Tri Yuliana Kolo Zulananta, Shohihunnatiq