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Sukardiman
Department Of Pharmaceutical Sciences, Faculty Of Pharmacy, UniversitasAirlangga, Surabaya
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Pemanfaatan Tanaman Obat Tradisional Sebagai Kontrasepsi Pria Nur Fadilla Achmad; Sukardiman Sukardiman
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 14, No 3 (2023): Juli - September 2023
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf14301

Abstract

With the increase in population, the government is promoting family planning programs to reduce the rate of population growth. In this case, the role of the man is the use of condoms and having a vasectomy. Men's participation in family planning is still low, and this can be related to aspects of knowledge, attitudes, practices, desired needs, limited information and accessibility of male contraceptive services, limited types of contraception and public perceptions. There are three main factors contributing to the low participation of men in family planning, including differences in gender roles between husband and wife, limited contraceptive methods, and men's lack of knowledge about contraception. This study aimed to discuss several plants related to contraception, especially herbal plants that had been tested through animal tests based on the literature and have been used by local people. Some plants that function as male contraceptives include: Gossypium sp., Enhalus acoroides, Solanum melongenaL., Curcuma longa L, Hibiscus rosasinensis, Psidium Guajava l., Azadirachta indica A. Juss, Abrus precatorius L. and Momordica charantia L., Litsea angulata, Quassia amara Linn., Aloe vera L., Cyperus rotundus L., Mirabilis jalapa. It was concluded that various types of plants have been identified as potential for male contraception, which could be further developed.Keywords: family planning; male contraception, traditional medicinal plants ABSTRAK Dengan meningkatnya jumlah penduduk, maka pemerintah menggalakkan program kelurga berencana untuk mengurangi laju pertumbuhan penduduk. Dalam  hal ini, peran pria adalah penggunaan kondom dan menjalani vasektomi. Partisipasi pria dalam keluarga berencana masih rendah, dan ini bisa berkaitan dengan aspek pengetahuan, sikap, praktek, kebutuhan yang diinginkan, keterbatasan informasi dan aksesibilitas terhadap pelayanan kontrasepsi pria, keterbatasan jenis kontrasepsi dan persepsi masyarakat. Ada tiga faktor utama yang membuat rendahnya partisipasi pria dalam keluarga berencana, antara lain perbedaan peran gender antara suami dan istri, metode kontrasepsi yang terbatas, serta kurangnya pengetahuan pria tentang kontrasepsi. Studi ini bertujuan untuk membahas beberapa tanaman yang terkait dengan kontrasepsi, khususnya tanaman-tanaman herbal yang sudah diuji melalui hewan uji berdasarkan literatur dan sudah digunakan oleh masyarakat lokal. Beberapa tanaman yang memiliki fungsi sebagai kontrasepsi pria antara lain: Gossypium sp., Enhalus acoroides, Solanum melongenaL., Curcuma longa L, Hibiscus rosasinensis, Psidium Guajava l., Azadirachta indica A. Juss, Abrus precatorius L. dan Momordica charantia L., Litsea angulata, Quassia amara Linn., Aloe vera L.,  Cyperus rotundus L., Mirabilis jalapa. Disimpulkan bahwa telah teridentifikasi berbagai jenis tanaman yang berpotensi untuk kontrasepsi pria, yang bisa dikembangkan lebih lanjut.Kata kunci: keluarga berencana; kontrasepsi pria, tanaman obat tradisional
Aktivitas Antiinflamasi (Peradangan) Berbagai Tumbuhan Dan Tanaman Obat Tradisional Nurhidayah -; Sukardiman -
Jurnal Penelitian Kesehatan SUARA FORIKES 2023
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf.v0i0.3203

Abstract

 ABSTRACTAnti-inflammatory is defined as drugs or drug classes that have the activity of suppressing or reducing inflammation. Inflammation or inflammation can be caused by various stimuli which include physical injury, infection, heat and antigen-antibody interactions.Anti-inflammatory is a local tissue reaction to infection or injury and involves more mediators. Utilization of traditional medicine needs to be used to minimize the side effects of non-steroidal and steroidal anti-inflammatory drugs. Since ancient times, the people of Indonesia and outside Indonesia have known and used plants and herbal plants or herbal medicines that have medicinal properties as one of their efforts to overcome various health problems. This review aims to discuss several plants related to anti-inflammation, especially herbal plants that have been tested on test animals based on the literature. Some plants that have anti-inflammatory activity include: (Eugenia Polyantha), (Callicarpa longifolia L.), (Ocimum americanum L.), (Morus alba L.), (Musa paradisiaca L.), (Aquilaria malaccensis Lamk.), (Allium cepa L.), (Volvariella sp), (Zingiber cassumunar Roxb.), (Euphorbia tirucalli L.), (Curcuma xanthorrhiza Roxb.), (Pluchea indica L.), (Averrhoa bilimbi), (annonasquamosa. L), (moringa oleifera lam.), (Coriandrum sativum L.), (Musa balbisiana).  Keywords: Inflammation, Anti-inflammation, Traditional Medicinal PlantsABSTRAKAntiinflamasi didefinisikan sebagai obat-obat atau golongan obat yang memilki aktivitas menekan atau mengurangi peradangan. radang atau inflamasi dapat di sebabkan oleh berbagai rangsangan yang mencakup luk-luka fisik, infeksi, panas dan interaksi antingen-antibodi. Antiinflamasi merupakan reaksi lokal jaringan terhadap infeksi atau cedera dan melibatkan lebih banyak mediator. Pemanfaatan obat tradisional perlu digunakan untuk meminimalisir efek samping obat golongan antiinflamasi non steroid dan steroid. Sejak zaman dahulu kala masyarakat Indonesia maupun luar Indonesia mengenal dan mneggunkan tanaman dan tumbuhan herbal atau obat herbal yang berkhasiat obat sebagai salah satu upanya dalam menanggulangi berbagai masalah kesehatan. Review kali ini bertujuan untuk membahas beberapa tanaman yang terkait dengan antiinflamasi khususnya tanaman-tanaman herbal yang sudah di lakukan pengujian terhadap hewan uji berdasarkan literature. Beberapa tanaman yang memiliki aktifitas antiinflamasi antara lain: (Eugenia Polyantha), (Callicarpa longifolia L.), (Ocimum americanum L.), (Morus alba L.), (Musa paradisiaca L.), (Aquilaria malaccensis Lamk.), (Allium cepa L.), (Volvariella sp), (Zingiber cassumunar Roxb.), (Euphorbia tirucalli L.), (Curcuma xanthorrhiza Roxb.), (Pluchea indica L.), (Averrhoa bilimbi), (annonasquamosa. L), (moringa oleifera lam.), (Coriandrum sativum L.), (Musa balbisiana).  Kata Kunci: Peradangan, Antiinflamasi, Tanaman Obat Tradisional
Pembentukan pojok herbal dan produk herbal (teh dan sirup) untuk meningkatkan kualitas kesehatan masyarakat di Desa Bengkaung, Kecamatan Batulayar, NTB Widyawaruyanti, Aty; Suciati, Suciati; Widiandani, Tri; Hidayati, Agriana Rosmalina; Hafid, Achmad Fuad; Purwanto, Djoko Agus; Purwitasari, Neny; Primaharinastiti, Riesta; Sukardiman, Sukardiman; Widyowati, Retno; Lahardo, Devanus; Ilmi, Hilkatul; Corry, Maylisa Natalia; Wicaksana, Firman; Edhi, Narendrani Sasmitaning; Hasan, Muhammad Amir
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 9, No 3 (2025): May
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v9i3.30199

Abstract

Abstrak Desa Bengkaung adalah desa yang terletak di kecamatan Batu Layar, Lombok Barat, Nusa Tenggara Barat.  Banyak potensi pada desa Bengkaung yang masih bisa dikembangkan diantaranya adalah sumber daya alam yang berlimpah. Namun, pemanfaatan sumber daya alam ini belum maksimal, yang disebabkan oleh kurangnya pengetahuan masyarakat mengenai manfaat dan  pengolahannya. Maka dilakukan pengabdian masyarakat yang berlangsung 2 tahap yaitu seminar terkait pojok herbal dan pelatihan pembuatan teh dan sirup dengan bahan kayu manis, kunyit, temu lawak, asam jawa, kapulaga untuk sediaan sirup serta bangle pada sediaan teh herbal yang berfungsi untuk meningkatkan kesehatan masyarakat. Kegiatan tersebut dilaksanakan  pada 25 Oktober 2024 dengan mitra terdiri dari  anggota IAI  kota Mataram dan kader PKK desa Bengkaung. Adapun materi pelatihan diberikan dengan metode ceramah dan metode praktik. Evaluasi dilakukan dengan cara pemberian pre-test dan post-test, kemudian dianalisis secara kuantitatif. Berdasarkan hasil pre-test dan post-test, diperoleh nilai rata-rata sebesar 60,94 dan 79.37, yang menunjukkan adanya peningkatan pengetahuan mitra terhadap materi penyuluhan yang diberikan. Teh daun salam dan JKP-Bangle dievaluasi dengan pengukuran kadar antioksidan dengan DPPH dan FRAP assay. Hasil analisis menunjukkan bahwa kadar antioksidan the daun salam dan JKP-Bangle dengan FRAP assay memperoleh kadar tertinggi tertinggi nilai masing-masing sebesar 1359.84±13.47 mg GAE/g berat kering dan 396.73±16.79 mg GAE/g berat kering. Aktivitas antioksidan yang tinggi ini mengindikasikan potensi manfaat kesehatan dalam menangkal stres oksidatif yang berhubungan dengan penyakit neurodegeneratif, kardiovaskular, dan diabetes. Kata kunci: Desa Bengkaung; pojok herbal; tanaman obat; antioksidan. Abstract Bengkaung Village is a village located in Batu Layar sub-district, West Lombok, West Nusa Tenggara.  There is a lot of potential in Bengkaung Village that can still be developed, including abundant natural resources. However, the utilization of these natural resources has not been maximized, this is caused by a lack of public knowledge regarding their benefits and processing. So community service was carried out which took place in 2 stages, namely seminars related to the herbal corner and training in making tea and syrup using cinnamon, turmeric, ginger, tamarind, cardamom for syrup and bangle preparations, as well as bangles for herbal tea preparations which function to improve health. public. This activity was carried out on 24-26 October 2024 with partners consisting of IAI members from Mataram city and PKK cadres from Bengkaung village. The training material is provided using the lecture method and the Experimental Learning method (direct implementation learning). Evaluation is carried out by giving a pre-test and post-test, then analyzed quantitatively. Based on the results of the pre-test and post-test, an average score of 60.94 and 79.37 was obtained, which indicates an increase in partners' knowledge of the extension material providedrn how to make innovative products from mangosteen fruit so that they can be produced commercially. Thus, in the long term it is expected to increase the income of the Songgon Village residents. Antioxidant levels of bay leaf tea and JKP-Bangle were evaluated using DPPH and FRAP assays. Analysis results showed that the highest antioxidant levels measured by the FRAP assay were 1359.84±13.47 mg GAE/g dry weight for bay leaf tea and 396.73±16.79 mg GAE/g dry weight for JKP-Bangle. This high antioxidant activity indicates potential health benefits in combating oxidative stress associated with neurodegenerative, cardiovascular, and diabetes-related diseases. Keywords: Songgon Village; herbal corner; medicinal plants; antioxidants.
Pharmacological Activity From Various Parts of Palm Oil (Elaeis guineensis Jacq.): A Review Widyowati, Retno; Putri, Anisa Yustikka; Sukardiman
Pharmaceutical Journal of Indonesia Vol. 10 No. 2 (2025)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Background: Elaeis guineensis Jacq. belongs to Arecaceae family. This plant originates from West Africa and is spread across Asia such as Indonesia. Various parts have been used traditionally and proven by scientific experiments derived for various medicinal purposes for the treatment many disease because contains many phytonutrients. Objective: This study was to explore the pharmacological activities of Elaeis guineensis Jacq. from various parts and the potential compound content. Methods: The method was a literature review by searching research data about Elaeis guineensis Jacq. from 2010 to 2024 was derived from Pubmed, ScienceDirect, Scopus, SpringerLink, NCBI and Google Scholar with the keywords of Elaeis guineensis Jacq, palm oil, in vivo, in vitro, in silico and pharmacologycal activity. Results: Elaeis guineensis Jacq. has composition of bioactive constituents including vitamin E,  fatty acid, fenolic, flavonoids, phenolics and karotenoid. With sample parts of leaves, fruits, seeds, and roots. Elaeis guineensis Jacq. has the ability as an pharmacology activity with the approach of in silico, in vitro and in vivo studies. The plant parts showed significant potential in various biological activities, including high antioxidant activity, significant antimicrobial effects against bacteria, anti-inflammatory, neuropharmacology, decreased blood glucose and insulin resistance, relatively safe toxicity tests at certain concentrations and protection against liver damage. The findings indicate the potential application in alternative medicine and nutraceutical development. Conclusion: Overall, this journal evaluated the pharmacological activities of various parts of Elaeis guineensis Jacq. through in silico, in vitro and in vivo pharmacological approaches showing that this species is a rich source of compounds. Further research is needed to develop therapeutic products based  on Elaeis guineensis Jacq. including clinical trials to ensure safety and efficacy in humans.
Pharmacological Activity From Various Parts of Palm Oil (Elaeis guineensis Jacq.): A Review Widyowati, Retno; Putri, Anisa Yustikka; Sukardiman
Pharmaceutical Journal of Indonesia Vol. 10 No. 2 (2025)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Background: Elaeis guineensis Jacq. belongs to Arecaceae family. This plant originates from West Africa and is spread across Asia such as Indonesia. Various parts have been used traditionally and proven by scientific experiments derived for various medicinal purposes for the treatment many disease because contains many phytonutrients. Objective: This study was to explore the pharmacological activities of Elaeis guineensis Jacq. from various parts and the potential compound content. Methods: The method was a literature review by searching research data about Elaeis guineensis Jacq. from 2010 to 2024 was derived from Pubmed, ScienceDirect, Scopus, SpringerLink, NCBI and Google Scholar with the keywords of Elaeis guineensis Jacq, palm oil, in vivo, in vitro, in silico and pharmacologycal activity. Results: Elaeis guineensis Jacq. has composition of bioactive constituents including vitamin E,  fatty acid, fenolic, flavonoids, phenolics and karotenoid. With sample parts of leaves, fruits, seeds, and roots. Elaeis guineensis Jacq. has the ability as an pharmacology activity with the approach of in silico, in vitro and in vivo studies. The plant parts showed significant potential in various biological activities, including high antioxidant activity, significant antimicrobial effects against bacteria, anti-inflammatory, neuropharmacology, decreased blood glucose and insulin resistance, relatively safe toxicity tests at certain concentrations and protection against liver damage. The findings indicate the potential application in alternative medicine and nutraceutical development. Conclusion: Overall, this journal evaluated the pharmacological activities of various parts of Elaeis guineensis Jacq. through in silico, in vitro and in vivo pharmacological approaches showing that this species is a rich source of compounds. Further research is needed to develop therapeutic products based  on Elaeis guineensis Jacq. including clinical trials to ensure safety and efficacy in humans.
Edukasi dan Pelatihan Pemanfaatan Tanaman Obat Keluarga di Desa Dlingo Bantul sebagai Upaya Pencapaian Tujuan SDGs di Bidang Kesehatan: Education and Training on the Use of Family Medicinal Plants in Dlingo Village, Bantul, as an Initiative to Support the Achievement of Health-Related SDGs Sukardiman, Sukardiman; Kusumawati, Idha; Handayani, Rosita; Sudjarwo, Sudjarwo; Munandar, Tristiana Erawati; Yusuf, Helmy; Diyah, Nuzul Wahyuning; Poerwono, Hadi; Purwanto, Bambang Tri
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 10 No. 7 (2025): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v10i7.10042

Abstract

Global health issues have become increasingly urgent following the COVID-19 pandemic, which resulted in approximately 6.6 million deaths by 2022. This impact has prompted communities to revert to traditional medicines, aligning with the National Development Planning System (RPJPN) 2005-2025, which promotes a health paradigm through traditional remedies. Community service activities were carried out in partnership with the Ngudi Makmur Farmer Group (POKTAN) in Dlingo Village, Bantul Regency. The primary objective of this activity was to enhance residents’ knowledge in Dlingo Village regarding the benefits and processing of Family Medicinal Plants (TOGA). The methods employed included material development, counseling sessions, question-and-answer discussions, and direct practical training in the preparation of aromatherapy candles. Evaluation was undertaken using pretests and posttests, which demonstrated a significant increase in participants’ understanding. The average scores rose from 81.67 (pretest) to 132.5 (posttest), with a statistically significant difference (p <0.001). These findings indicate that the counseling was effective in improving knowledge about TOGA and its utilization in producing aromatherapy candles. Such activities not only enhance awareness but also reinforce community autonomy in managing traditional medicinal resources, in line with the health-related objectives of the Sustainable Development Goals (SDGs).
Edukasi Pemanfaatan Obat Tradisional, Aromaterapi, dan Akupresur untuk Mengurangi Kelelahan pada Tenaga Kesehatan dan Pasien di Rumah Sakit Universitas Airlangga: Educational Intervention on the Use of Traditional Medicine, Aromatherapy, and Acupressure to Reduce Fatigue Among Healthcare Workers and Patients at Airlangga University Hospital Handayani, Rosita; Sukardiman, Sukardiman; Widyowati, Rr. Retno; Imandiri, Ario; Ekasari, Wiwied; Sudjarwo, Sudjarwo; Hafid, Achmad Fuad; Wahyuni, Tutik Sri; Lestari, Maria Lucia Ardhani Dwi; Sulistyowaty, Melanny Ika
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 10 No. 8 (2025): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v10i8.10041

Abstract

Excessive fatigue and burnout are serious issues frequently experienced by healthcare workers and patients with chronic illnesses, particularly within high-pressure healthcare environments. These conditions not only impair the performance of medical personnel but also negatively affect the therapeutic outcomes of patients. To address this problem, a community service activity was conducted through educational outreach on fatigue and burnout management, utilizing acupressure, traditional remedies, and aromatherapy. The program involved 49 participants, including healthcare workers and Surabaya's chronic disease patients. Held on September 11, 2024, the activity employed lectures and two-way discussions as its primary methods. The material covered included traditional medicine, basic acupressure techniques, and training in roll-on and massage oil aromatherapy preparation. A structured module was developed to enhance learning effectiveness, and participants' comprehension was evaluated through pre- and post-tests. Statistical analysis using a paired t-test revealed a significant improvement in participants' understanding (p <0.01), with an average score increase of 19.8%. This initiative demonstrates that practical and interactive education can effectively improve participants' knowledge and skills in managing fatigue and burnout. Therefore, the outcomes of this activity are essential as a promotive and preventive effort to support the physical and mental well-being of vulnerable groups in healthcare settings.
Physicochemical Profile and Stability of Red Ginger (Zingiber officinale var. rubrum) SNEDDS as Potential Aphrodisiac Pratama, Edo; Aly, M. Ainun Najib; Istiqamah, Farida; Widyowati, Retno; Sukardiman, Sukardiman
Borneo Journal of Pharmacy Vol. 8 No. 3 (2025): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v8i3.9691

Abstract

This study investigated the stability of a Self-Nanoemulsifying Drug Delivery System (SNEDDS) formulated with Zingiber officinale var. rubrum (red ginger) extract. SNEDDS formulations, composed of an oil phase, co-surfactant, and surfactant, are designed to create stable isotropic mixtures, critical for drug delivery systems. Prior to assessing long-term physical stability, the optimal Z. officinale var. rubrum SNEDDS preparation underwent comprehensive characterization, including evaluation of emulsification time, pH, particle size, polydispersity index (PDI), and zeta potential. Subsequent physical stability assessments involved rigorous centrifugation, hot-cold, and freeze-thaw cycles. The results demonstrated an emulsification time of ≤1 minute, a pH value of 5.04±0.05, and a particle size of 14.92±0.7 nm, indicative of a nanoscale dispersion. The PDI was 0.282, and the zeta potential was −18.57±1.30 mV, suggesting good colloidal stability. Crucially, throughout six cycles of centrifugation, hot-cold, and freeze-thaw stress tests, the Z. officinale var. rubrum extract SNEDDS exhibited no signs of phase separation, sedimentation, cracking, or creaming. These findings collectively confirm that the prepared Z. officinale var. rubrum extract SNEDDS meets critical physicochemical characteristics and demonstrates excellent physical stability, positioning it as a promising candidate for further development as a natural extract delivery system.
IDENTIFIKASI SENYAWA FITOKIMIA EKSTRAK ETANOL 70% AKAR GINSENG KUNING (RENNELLIA ELLIPTICA KORTH.) MENGGUNAKAN LC-MS/MS DAN AKTIVITAS AFRODISIAKA SECARA IN SILICO Istiqamah, Farida; Sukardiman, Sukardiman; Widyowati, Retno
Jurnal Wiyata Penelitian Sains dan Kesehatan Vol 11 No 2 (2024)
Publisher : LP2M IIK (Lembaga Penelitian dan Pengabdian Masyarakat Institut Ilmu Kesehatan) Bhakti Wiy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56710/wiyata.v11i2.870

Abstract

Abstrak Latar belakang: Rennellia elliptica Korth. secara tradisional digunakan sebagai zat afrodisiak. Dilihat dari potensinya, bukti ilmiah ekstrak tumbuhan ini sebagai penghambat phosphodiesterase-5 masih belum dilakukan Tujuan: Penelitian ini bertujuan untuk mengetahui senyawa fitokimia yang terdapat pada ekstrak etanol 70% tanaman rennellia elliptica Korth. menggunakan LC-MS/MS dan aktivitas afrodisiakan secara in silico. Metode: Ekstrak etanol rennellia elliptica Korth. dianalisis menggunakan LC-MS/MS selanjutnya senyawa tersebut digunakan sebagai senyawa ligan dalam penambatan molekuler untuk mengetahui afinitas pengikatan konstituen fitokimia tersebut terhadap protein target phosphodiesterase 5 (PDB ID: 2H42). Hasil: Ditemukan 17 komponen senyawa antara lain golongan terpenoid, fenilpropanoid, antrakuinon dan flavonoid. Berdasarkan studi in silico dari 17 senyawa yang dianalisis dengan LC-MS/MS, Dulxanthone B (∆G=-9,52 kkal/mol) menunjukkan afinitas tertinggi untuk berikatan dengan target protein. Simpulan: Senyawa fitokimia dari rennellia elliptica Korth. dapat berfungsi sebagai terapi tambahan dalam penemuan obat untuk pengobatan yang menghambat phosphodiesterase 5. Abstract Background: Rennellia elliptica Korth. is traditionally used as an aphrodisiac substance. Judging from its potential, scientific evidence of this plant extract as a phosphodiesterase-5 inhibitor has yet to be conducted. Objective: . This research aims to determine the phytochemical compounds contained in the 70% ethanol extract of the Rennellia elliptica Korth plant. using LC-MS/MS. Method: The ethanol extract of rennellia elliptica Korth. was analyzed using LC-MS/MS and then the compounds were used as ligand compounds in molecular docking to determine the binding affinity of the phytochemical constituents to the target protein phosphodiesterase 5 (PDB ID: 2H42). Results: 17 compound components were found, including terpenoids, phenylpropanoids, anthraquinones and flavonoids. Based on in silico studies of 17 compounds analyzed by LC-MS/MS, Dulxanthone B (∆G=-9.52 kcal/mol) showed the highest affinity for binding to protein targets.. Conclusions: Phytochemical compounds from Rennellia elliptica Korth. may serve as an adjunct therapy in drug discovery for treatment that inhibits phosphodiesterase 5.
Transformasi Sosial Melalui Dialog Etis: Menyemai Toleransi Dalam Keberagaman beragama Sukardiman; Isna Rahmayani
Ulul Albab: Journal Da`wah and Social Religiosity Vol. 3 No. 1 (2025): Ulul Albab: Journal Da`wah and Social Religiosity
Publisher : P3M STID Mustafa Ibrahim Al-Ishlahuddiny Kediri Lombok Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69943/5swmca66

Abstract

Abstrak Transformasi sosial memalui dialog etis dalam upaya untuk menyemai toleransi ini sangat penting di tengah keragaman bangsa Indonesia yang sewaktu-waktu berpotensi melahirkan gesekan sosial, sedangkan manusia tidak bisa hidup sendiri, pasti membutuhkan orang lain atau disebut dengan istilah zone politicon, dan dialog etis menjadi alternatif yang progresif untuk transformasi sosial. Tulisan ini berupaya untuk menjelaskan prinsip, tantangan peran dan strategi membangun dialog yang etis dalam konteks keberagamaan dengan metode studi literatur. Prinsip dasar dialog etis (1) Sikap saling menghormati; (2) Kejujuran dan Keterbukaan; (3) Non-Konfrontatif; (4) Mencari Kesepahaman; (5) Kesetaraan dalam Berdialog; (6) Komitmen terhadap Harmoni Sosial. Kemudian peran dialog yang etis; (1) meningkatkan pemahaman dan penghargaan terhadap keberagaman, (2) mendorong solidaritas sosial; (3) menciptakan kesepakatan nilai-nilai universal; (4) membentuk kepemimpinan inklusif dalam beragama; (5) menguatkan identitas sosial yang positif; (6) menghasilkan aksi sosial yang kolaboratif. Tantang dalam membangun dialog yang etis ditengah keberagaman agama; (1) prasangka dan stereotip antar agama; (2) fanatisme dan eksklusivisme agama; (3) kurangnya pendidikan dan pemahaman multikulturalisme; (4) kepentingan sosial politik dan ekonomi; (5) perbedaan penafsiran dan pemahaman ajaran agama. Terakhir, strategi untuk menciptakan dialog yang etis; (1) Meningkatkan literasi keberagaman; (2) Memperkuat komitmen pada nilai-nilai universal; (3)Membangun kesepakatan dalam perbedaan; (4) Menciptakan forum dialog yang inklusif dan setara; (5) Memanfaatkan teknologi dan media dengan bijak; (6) Meningkatkan kerja sama antar lembaga keagamaan. (7) fokus pada transformasi sosial yang nyata. Sehingga dengan prinsip, tantangan, peran dan strategi atas tentu menjadi modal penting untuk menciptakan tolernasi di tengah keragaman agama.   Kata kunci: transformasi sosial, dialog, etis, toleransi.
Co-Authors A. Dinar Ambarwati Achmad Fuad Hafid Adam Hermawan Al ‘Amali, Mayla Khayra Aly, M. Ainun Najib Anak Agung Gede Sugianthara Annisa Farida Muti Arie Ika Susanty Ario Imandiri, Ario Aty Widyawaruyanti Awik Puji Dyah Nurhayati Bambang Prayogo Bambang Sugiharto Bambang Tri Purwanto Corry, Maylisa Natalia Dewi Hidayati Dini Retnowati Diyah, Nuzul Wahyuning Djoko Agus P. Djoko Agus Purwanto Dwi Ningsih Dwi Riani Oktavia Palupi Edhi, Narendrani Sasmitaning Edy Listanto Edy Meiyanto Edy Meiyanto Emma Rahmawati Emma Rahmawati Engel, Daniella Elizabeth Eny I. Riyanti Esti Hendradi Faisal Akhmal Muslikh Hadi Poerwono Handayani, Rosita Hardiyanti, Andi Sry Hasan, Muhammad Amir Hidayati, Agriana Rosmalina I.A.A. Widhiartini Idha Kusumawati Iis Wahyuningsih Ilmi, Hilkatul Isna Rahmayani Isnaeni Istiqamah, Farida Junaidi Khotib Juni Ekowati Kholis Amalia Nofianti Kusmana Kusmana Lahardo, Devanus Marcellino Rudyanto Maria Lucia Ardhani Dwi Lestari Melanny Ika Sulistyowaty Miatmoko, Andang Misgiati, Misgiati Munandar, Tristiana Erawati Noor Erma NS Nur Fadilla Achmad Nurhidayah - Nuri Nuri Oka Adi Parwata Prasetyanti, Intan Kris Pratama, Edo Purwitasari, Neny Putri, Anisa Yustikka Rahmawati, Emma Ramadhani, Firmansyah Ardian Rarastoeti Prastiwi Retno Sari Retno Widyowati Riesta Primaharinastiti, Riesta Rijal, Agus Syamsur Roihatul Mutiah Shigeru Sasaki Shigeru Sasaki Siti Maimunah Siti Zulaikah Suciati Suciati Sudjarwo Sudjarwo Sudjarwo Suharjono, Suharjono Sulistiyono, Ilham Robbynoor Sulistyowati, Melanny Ika SUZANA, SUZANA Taufikurrahman Taufikurrahman Taufikurrahman Toto Hadiarto Tri Dewanti W. Tri J. Santoso Tri Sundari Tri Widiandani Tutik Sri Wahyuni Tutuk Budiati Wicaksana, Firman Widiyaningsih, Arum Widyowati , Retno Widyowati, Rr. Retno Wijayanti Pujitono Win Darmanto Wiwied Ekasari Yurika Sastyarina Yurika Sastyarina Yurika Sastyarina Yusuf, Helmy