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All Journal Jurnal Penelitian Pertanian Terapan Gorontalo Agriculture Technology Journal Jambura Journal of Chemistry JPBIO (Jurnal Pendidikan Biologi) NUKHBATUL 'ULUM : Jurnal Bidang Kajian Islam BUSTANUL FUQAHA: Jurnal Bidang Hukum Islam Mahaguru: Jurnal Pendidikan Guru Sekolah Dasar Journal SAGO Gizi dan Kesehatan Jurnal Disrupsi Bisnis Jurnal Pengabdian kepada Masyarakat AL-BASHIRAH: Journal of Islamic Studies Jurnal Pengabdian Masyarakat (ABDIRA) Jurnal Agrisistem J-Alif : Jurnal Penelitian Hukum Ekonomi Syariah dan Budaya Islam Munggai: Jurnal Ilmu Perikanan dan Masyarakat Pesisir Ilmu Komputer untuk Masyarakat Borneo Community Health Sevice Journal JEUMPA AL-KHIYAR: Jurnal Bidang Muamalah dan Ekonomi Islam Jurnal PADE: Pengabdian & Edukasi Jurnal Pharmacopoeia AL-QIBLAH: Jurnal Studi Islam dan Bahasa Arab Innovative: Journal Of Social Science Research Indonesian Journal of Pharmacy and Natural Product JIP: Jurnal Ilmu Pendidikan Nasuwakes : Jurnal Kesehatan Ilmiah Jurnal Ilmiah Farmasi Simplisia Jurnal Bakti Masyarakat Manajemen Amanisal: Jurnal Teknologi dan Manajemen Perikanan Tangkap Journal Of Chemical Process Engineering Al-khidmah: Jurnal Pengabdian dan Pendampingan Masyarakat ZONA: Jurnal Pengabdian Masyarakat
Munira Munira, Munira
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Journal : Jurnal Ilmiah Farmasi Simplisia

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UJI EFEKTIVITAS EKSTRAK BIJI PEPAYA (Carica papaya L.) SEBAGAI ANTHELMINTIK TERHADAP CACING Ascaridia galli: UJI EFEKTIVITAS EKSTRAK BIJI PEPAYA (Carica papaya L.) SEBAGAI ANTHELMINTIK TERHADAP CACING Ascaridia galli Khaliza, Nur; Handayani, Rini; Aulianshah, Vonna; Zakiah, Noni; Munira, Munira; Nindia, Yuni
JURNAL ILMIAH FARMASI SIMPLISIA Vol. 5 No. 1 (2025): Juni 2025
Publisher : Jurusan Farmasi, Politeknik Kesehatan Kementerian Kesehatan Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/jifs.v5i1.890

Abstract

Infeksi cacing masih menjadi masalah kesehatan yang umum di negara tropis seperti Indonesia. Salah satu tanaman yang banyak dibudidayakan di Indonesia adalah pepaya (Carica papaya L.), yang bijinya diketahui memiliki sifat anthelmintik, tetapi biji pepaya seringkali dibuang tanpa dimanfaatkan. Penelitian ini bertujuan untuk mengetahui efek ekstrak biji pepaya terhadap mortalitas cacing Ascaridia galli. Sebanyak 75 ekor cacing digunakan dalam penelitian ini, dibagi dalam tiga kali ulangan, masing-masing terdiri dari lima kelompok perlakuan: kontrol negatif (NaCl 0,9%), kontrol positif (Pirantel Pamoat 0,5%), serta ekstrak biji pepaya dengan konsentrasi 10%, 15%, dan 20%. Penilaian dilakukan berdasarkan skor gerakan cacing setelah inkubasi selama 12, 24, dan 36 jam. Skor 2 diberikan jika seluruh tubuh cacing bergerak, skor 1 diberikan jika cacing tidak bergerak namun masih hidup, dan skor 0 diberikan jika cacing mati. Hasil uji in vitro menunjukkan bahwa ekstrak biji pepaya 10% menyebabkan kelumpuhan pasca inkubasi 12 jam pertama dan kematian seluruh cacing setelah 24 jam pasca inkubasi. Konsentrasi 15% dan 20% menyebabkan kematian pada semua cacing pasca inkubasi 12 jam pertama. Hasil penelitian ini dapat disimpulkan bahwa ekstrak biji pepaya konsetrasi 10%, 15% dan 20% efektif sebagai anthelmintik terhadap Ascaridia galli.
Uji Aktivitas Antioksidan Ekstrak Beberapa Jenis Bunga dengan Metode DPPH (1,1-diphenyl-2-picrylhydrazil) munira, munira; Nasir, Muhammad; Halimatussakdiah
JURNAL ILMIAH FARMASI SIMPLISIA Vol. 4 No. 1 (2024): Juni 2024
Publisher : Jurusan Farmasi, Politeknik Kesehatan Kementerian Kesehatan Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/jifs.v4i1.564

Abstract

Several ornamental plants such as roses (Rosa sp.), hibiscus flowers (Hibiscus rosa-sinensis) and butterfly pea flowers (Clitoria ternatea) function as medicinal ingredients. These flowers have varying colors. The varying colors of these flowers are caused by anthocyanin compounds which are part of the secondary metabolites of flavonoids. Flavonoids are part of the group of phenolic compounds and flavonoids have the ability to act as antioxidants. This research aims to determine the antioxidant activity levels of rose, hibiscus and butterfly pea flower extracts. This research is experimental. Extraction was carried out by maceration using 70% ethanol solvent. Determination of the antioxidant activity test using the DPPH (1,1-diphenyl-2-picrylhydrazil) free radical scavenging method which was measured using a UV-Vis spectrophotometer. The results of the antioxidant activity test showed that rose flower extract had an IC50 value of 18.39 µg/ml and hibiscus flowers had an IC50 value of 3.56 µg/ml and butterfly pea flower had an IC50 value of 9.44 µg/ml. Hibiscus flowers have higher antioxidant activity than roses and butterfly pea flowers.
Co-Authors Abbas, Ririn Yulandari Abdullah, Syahrul Mubarak Abidin, Jenny Agus Yudiawan Agustin, Nesti Ahad, Yeny Aini, Quratul Ainun Mardiah Akhmad Hanafi Dain Yunta Aksiyah, Eli Alam, Aztri Fithrayani Andi Aladin Andi Sumardin, Andi Andriani, Rida Yuliana Andriani, Rika Andzala Cahyani Annisa Miftahussaadah Ansyari, Ilman Indra Arman, Muh Asri Jumadewi Aulianshah, Vonna Awalia, Pertiwi Azzahra, Lilisa Azzahrah, Andi Chairunnisa Chairunnisa Cut Aja Nuraskin Daniel Happy Putra Darnengsih, Darnengsih Dedi Setiawan Dewi Indriani Diah Ayu Wulandari, Diah Ayu ELIHAMI, ELIHAMI Ergantara, Rani Ismiarti Fangohoi, Latarus Fardilla, Cut Fathur Rahman Firdha Razak, Firdha Frengki Frengki, Frengki Gusnawati, G. Gusnawati, Gusnawati Gusriani Gusriani Haeruddin Haeruddin Halimatussakdiah Hardyantoro, Vicko Tri Hasan Hasan Heryansyah Humairah Ahsan Irwana Wahab, Irwana Iswandi, Muh Jadid, Miftahul Kadja, Ranan Karim, Izma Khaerunnisa Khaerunnisa, Khaerunnisa Khairani, Zulfa Rahmalia Khaliza, Nur Khotibul Umam L, Andi Besse Sumpala La Ima, Tjameria Lilit, Sona Wanda M. Hatta Mahmuddin, Ronny Mailisa, Wiska Marina Marina MARLINA, LILIS Maulida, Aura Miska, Laiyana Misran Misran Muhamad Saddam Nurdin Muhammad Nasir Muhammad Nusran muhammad rizky, muhammad Mujiati, Asfi Mustafiah Mustafiah Muttazimah, Muttazimah Nasma, Intan Maulida Natalina Natalina Nazira, Jihan Nidaul Haq Nindia, Yuni Noni Zakiah Nur Fadillah, Nur Nuraeni Nuraeni Nurul Chairany Nurulrahmatia, Nafisah Nurzahwa, Cindy Lusiana Nusbah, Syam Suryanto octamelia, Mega Pamudi, Berwi Fazri Pengerang, Fitrah Puspitasari, Mutiara Dwi Putri, Dira Nita Yulia Rabiudin, Rabiudin Rachmanto, Muhammad Resky Rahayu, Eka Sri Rahmaniah Malik Ramadhani, Uni Rasidah Rasidah Rasmi Rasmi, Rasmi Reca Reca Rendy Retnaningati, Dewi Rini Handayani Risdayani, Risdayani Rony, Zahara Tussoleha Rosita, Nopi Rukka, Hermaya Sam, Nur Fitriana Sam, Zulfiah Samiun, Winda La Septiani, Mimin Siti Suarni, Siti Suarni Sri Ujiana Putri Suparman Suparman Takdir Syarif Uswanas, Wita Wahyuni, Etty Wilda Reni Yasin, Nur Azizah Yendari, Tirza Dwi Zakiyah Darajat Zartinawati, Nurfitrah