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Journal : Jurnal Katalisator

Optimasi Waktu Penyulingan Terhadap Kadar dan Karakteristik Minyak Atsiri Daun Patikala(Etlingera elatior (Jack) R.M.Smith) Yuri Pratiwi Utami; Aprilia Matelda Dwi Kristiyanti; Imrawati
JURNAL KATALISATOR Vol. 7 No. 2 (2022): jurnal Katalisator Volume 7 No 2, Oktober 2022
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (169.414 KB) | DOI: 10.62769/katalisator.v7i2.979

Abstract

Patikala (Etlingera elatior (Jack) R. M. Smith) merupakan salah satu jenis tanaman dari suku Zingiberaceae dan merupakan tanaman yang multiguna mulai dari rimpang sampai bunga yang memiliki potensi untuk menghasilkan minyak atsiri, salah satunya pada bagian daun. Tujuan dilakukannya penelitian ini untuk mengetahui pengaruh variasi waktu penyulingan terhadap kadar minyak atsiri yang diperoleh. Bahan yang digunakan merupakan simplisia kering dari daun patikala dengan variasi waktu penyulingan 4, 5 dan 6 jam, penyulingan dilakukan dengan menggunakan metode destilasi uap. Dari  hasil penelitian ini rendamen dengan persen terbanyak ada pada waktu penyulingan 6 jam  yang menghasilkan persen rendamen yaitu 0,228%. Sedangkan untuk kadar minyak atsiri, didapatkan pada waktu penyulingan 4 jam yaitu 0,15%v/b dengan terbacanya satu  karakteristik minyak atsiri dengan nama komponen 2-Decen-1-ol  (C10H20O), untuk waktu penyulingan 5 jam yaitu 0,1%v/b dengan satu karakteristik minyak atsiri yang terbaca dengan nama komponen yang sama pada penyulingan 4 jam yaitu 2-Decen-1-ol  (C10H20O) dan 6 jam yaitu 0,125%v/b dengan terbacanya tiga karakteristik minyak atsiri yaitu 2-Decen-1-ol (C10H20O), 2,6-Octadine, 2,4-dimethyl-1 (C10H18) dan Spiro[4.5]decen-7-one,1,8-dimethyl-8,9-epoxy-4-isopropyl- (C15H24O2). Penelitian ini menunjukkan, waktu penyulingan dapat memberikan pengaruh terhadap hasil rendamen dan karakteristik yang didapatkan.  
SKRINING FITOKIMIA DAN UJI SITOTOKSIK EKSTRAK ETANOL DAUN ANDONG MERAH (Cordyline fruticosa) Yuri Pratiwi Utami Usman; Ainun Jariah
JURNAL KATALISATOR Vol. 8 No. 1 (2023): Jurnal Katalisator Volume 8 No. 1, April 2023
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (171.727 KB) | DOI: 10.62769/katalisator.v8i1.1704

Abstract

Cordyline fruticosa is a plant used in traditional medicine. C. fruticosa plant is empirically efficacious for stopping bleeding, eliminating swelling, C. fruticosa leaves are efficacious as a wound medicine and medicine for hemorrhoids and flatulence. This study aims to screening for phytochemical compounds and to determine the potential for toxicity using the BSLT (Brine Shrimp Lethality Test) method and in C. fruticosa leaf extract. The research method starts with the samples extracted using the maceration method for 3 x 24 hours and is continued with remaceration using 70% ethanol solvent. Furthermore, phytochemical screening tests and cytotoxic tests were carried out using the BSLT (Brine Shrimp Lethality Test) method, which is one method that is widely used to search for new anticancer compounds derived from plants, testing using Artemia salina Leach shrimp larvae aged 48 hours with a concentration of 20, 40, 60, 80 and 100 µg/mL and seawater as a control. Observations Artemia salina Leach was observed for 24 hours. The results showed that the ethanol extract of red andong leaves contains a class of flavonoids, triterpenoids, saponins, and tannins. The LC50 value of the ethanol extract of red andong leaves, namely 60.36 µg/mL, is included in the toxic category
KLT-BIOAUTOGRAFI EKSTRAK DAUN PATIKALA (Etlingera elatior (Jack) R.M. Sm) MENGGUNAKAN VARIASI PELARUT Yuri Pratiwi Utami; Imrawati Imrawati; Hamdayani Lance Abidin; Tuti Handayani
JURNAL KATALISATOR Vol. 8 No. 2 (2023): Jurnal Katalisator Volume 8 No. 2, Oktober 2023
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v8i2.2459

Abstract

Tanaman patikala (Etlingera elatior (Jack) R.M. Sm.) digunakan masyarakat sebagai obat penyakit kulit dan antimikroba pada pangan. Telah banyak dipelajari senyawa antibakteri dari tanaman tetapi antibakteri dengan analisis KLT Bioautografi dari daun patikala belum banyak yang mempelajarinya.  Tujuan dari penelitian ini melakukan analisis untuk mengetahui potensi daun patikala dari berbagai jenis pelarut berdasarkan tingkat kepolaran yang berperan sebagai antibakteri. Metode ekstraksinya adalah maserasi dengan beberapa pelarut yaitu n-heksan, etil asetat, dan etanol. Kemudian dilakukan aktivitas antibakterinya menggunakan analisis KLT-Bioautografi. Analisis golongan senyawa antibakteri  dilakukan dengan KLT-Bioautografi kontak menggunakan eluen n-heksan (7) : etil asetat (3) untuk ekstrak etanol dan n-heksan (8) : etil asetat (2) untuk ekstrak etil asetat dan n-heksan terhadap bakteri Staphylococcus aureus dan bakteri Escherichia coli. Diperoleh 4 noda untuk ekstrak etanol dengan Rf 0,3, 0,8, 0,9 dan 0,94, pada ekstrak etil asetat diperoleh 4 noda dengan Rf 0,2, 0,6, 0,8 dan 0,9 sedangkan pada ekstrak n-heksan diperoleh 5 noda dengan Rf 0,18, 0,6, 0,7, 0,9 dan 0,96. Hasil KLT-Bioautografi menunjukkan golongan senyawa yang bersifat antibakteri, pada ekstrak etil asetat ada pada Rf 0,2 dan pada ekstrak n-heksan ada pada Rf 0,18 . Dapat disimpulkan bahwa noda yang di identifikasikan sebagai antibakteri adalah golongan senyawa flavonoid
Antioksidan Ekstrak Daun Patikala (Etlingera elatior (Jack) R.M. Sm) Penangkal Radikal Bebas ABTS Asal Enrekang Sulawesi Selatan Yuri Pratiwi Utami; Risfah Yulianty; Yulia Yusrini Djabir; Gemini Alam
JURNAL KATALISATOR Vol. 8 No. 2 (2023): Jurnal Katalisator Volume 8 No. 2, Oktober 2023
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v8i2.2572

Abstract

Daun patikala (Etlingeraelatior Jack. R.M. Smith) adalah salah satu tanaman yang dapat digunakan untuk menangkal radikal bebas. Metabolit sekunder tanaman termasuk flavonoid, alkaloid, tannin, dan fenol, yang dapat berfungsi sebagai antioksidan, telah banyak dipelajari antioksidan dari tanaman tetapi antioksidan dari daun patikala belum banyak yang mempelajari dan mengkajinya. Tujuan penelitian ini adalah untuk menentukan kekuatan antioksidan ekstrak daun patikala (Etlingeraelatior Jack R.M. Smith) dalam meredam radikal bebas dengan metode ABTS, asal Enrekang Sulawesi Selatan merupakan asal sampel tanaman yang dietahui bahwa faktor tumbuh suatu tanaman mempengaruhi kadar metabolite sekunder yang berpotensi sebagai antioksidan. Proses ekstraksi dilakukan melalui maserasi menggunakan pelarut, yaitu etanol 70%. Untuk menilai aktivitas antioksidan, digunakan metode peredaman ABTS (2,2'-azino-bis-{3-etilbenzotiazolin-6- asamsulfonat}), diukur pada panjang gelombang 745 nm, lebih rendah dari panjang gelombang vitamin C (739 nm). Hasil yang diperoleh yaitu nilai IC50rata-rata sebesar 37,98 ppm untuk ekstrak etanol daun patikala. Aktivitas antioksidan ekstrak etanol daun patikala sangat kuat karena nilai IC50 kurang dari 50 ppm dan vitamin C 0,15 ppm.Kesimpulan pada penelitian ini yakni bahwa ekstrak etanol daun patikala berpotensi menangkal radikal bebas ABTS sehingga penelitian ini dapat berkonstribusi sebagai sumber informasi pemanfaatan daun patikala sebagai antioksidan.
ARTICLE REVIEW: ANTIOXIDANT POTENTIAL OF HERBAL or PLANTS OF OUTER BADUY COMMUNITY IN BANTEN AS COSMETIC RAW MATERIALS Yuri Pratiwi Utami; Anto Apriyanto; Nurhayani; Agus Firmansyah; Firdaus
JURNAL KATALISATOR Vol. 9 No. 2 (2024): Jurnal Katalisator Volume 9 No.2, Oktober 2024
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v9i2.3394

Abstract

Antioxidants can bind free radicals, inhibit oxidative stress, stimulate oxygen and tighten the skin so as to prevent premature aging. An increase in the number of free radicals, an increase in age, and excessive exposure to ultraviolet light can accelerate the aging process or cause premature aging. Premature aging can be prevented by using cosmetics that contain natural antioxidants derived from plants. There are many herbal plants that are empirically used by the Baduy community as potential antioxidants. Proof of antioxidant activity can be done by testing the effects on each herbal plant conducted by several previous researchers. The purpose of this article is to provide information about which plants have the potential as antioxidants as cosmetic raw materials through journal literature searches in electronic databases. Some herbal plants in Baduy outside are papaya, cat whiskers, miana, weeds, kencur, guava, red ginger, betel nut, secang and kecombrang. Secondary metabolites in plants that are most influential as cosmetics include flavonoids and phenolics.
OPTIMIZATION OF ANTIOXIDANT ACTIVITY OF 96% ETHANOL EXTRACT OF Chromolaena odorata L. ABTS RADICAL PROPHYLACTIC Usman, Yuri Pratiwi Utami; Rahmah Mustarin; Imrawati; Nurzadrina Wahyuddin; Suhaera; Besse Yuliana
JURNAL KATALISATOR Vol. 9 No. 1 (2024): Jurnal Katalisator Volume 9 No.1, April 2024
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v9i1.2817

Abstract

Choromolaena odorata L. is one of the plants used as an antioxidant. This research aims to determine the optimization of the antioxidant activity of 96% ethanol extract of C. odorata L. leaves using the ABTS method, a variety of drying techniques. Previous research has tested antioxidant activity using one drying technique, whereas this research uses a variety of drying techniques because the sample drying technique will affect its activity. Simplicia is obtained from various drying techniques. Then the simplicia was organoleptically tested and its water content was measured using the distillation method. The ethanol extract of Tacklean leaves was carried out using the maceration method using 96% ethanol solvent, then phytochemical screening was carried out using the TLC method and the antioxidant activity test of the ethanol extract of C. odorata L leaves was carried out using the ABTS method. The formation of the ABTS radical cation [2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) forms the basis of one of the spectrophotometric methods that has been applied to the measurement of total antioxidant activity of plants. The research results from the three drying techniques (50°C oven, direct sun drying, and air drying) showed organoleptic results in successive colors (brown, chocolate and dark green), while for shape and odor, namely dry leaves and a distinctive odor. The water content of simplicia ranges from 7.52-9.31%, soaked extract 8.4-10.3% and IC50 23.287-29.064 µg/mL and quarcetin as a comparison with IC50 2.292 µg/mL. Phytochemical screening results contain alkaloids, flavonoids, steroids and tannins. Oven drying at 50°C produced the greatest antioxidant activity with an IC50 value of 23.287 µg/mL which indicates very strong antioxidant power, although the antioxidant activity with a variety of drying techniques was all in the very strong category because it was <50 µg/mL.
TOTAL FLAVONOID LEVELS AND ANTIOXIDANT ACTIVITY OF KERSEN LEAF EXTRACT (muntingia calabura L.) L A, Hamdayani; Fitriyanti Jumaetri Sami; Yuri Pratiwi Utami
JURNAL KATALISATOR Vol. 9 No. 1 (2024): Jurnal Katalisator Volume 9 No.1, April 2024
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v9i1.2831

Abstract

Kersen leaves (Muntingia calabura L.) are plants that contain many secondary metabolites, one of which is flavonoids that can act as antioxidants. This study aims to determine the total content of flavonoids which also have the potential as antioxidants in cherry leaves using the DPPH method (2,2-diphenyl-1-picrylhidrazyl) with various filters, namely 70% ethanol, ethyl acetate and n-hexan. Testing of total flavonoid content was carried out using AlCl3 reagent and measured using spectrophotometry at a wavelength of 422 nm. Antioxidant activity testing was measured at an absorption wavelength of 516 nm. The results showed the total flavonoid content of 70% ethanol filter leaf extract as much as 8.13 (mgQE/g), ethyl acetate as much as 8.32 (mgQE/g) and n-hexan as much as 18.96 (mgQE/g). antioxidant activity of cherry leaves using DPPH method (2,2-diphenyl-1-picrylhidrazyl) with filter variations. 70% ethanol extract of cherry leaves has an IC50 value of 7.56 μg/mL, ethyl acetate extract with an IC50 value of 36.05 μg/mL, and n-hexan extract with an IC50 value of 21.33 μg/mL. From the results obtained it can be concluded that the highest antioxidant activity is contained in 70% ethanol extract of 7.56 μg/mL.
ANTIBACTERIA ACTIVITY ETHANOL EXTRACT OF ACHRAS ZAPOTA L. FRUIT AND LAGENARIA SICERARIA (MOLINA) STANDL. AGAINST SALMONELLA TYPHI Saldi Hapiwaty; Yuri Pratiwi Utami; Imrawati; Mahfuzun Bone; Nurjannah Bachri; Rahmah Mustarin; Ainun Jariah; Zahira Amody; Benedikta Winne Angela
JURNAL KATALISATOR Vol. 9 No. 2 (2024): Jurnal Katalisator Volume 9 No.2, Oktober 2024
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v9i2.3103

Abstract

The Synergistic of antibacterial is an interaction of two antibacterial agents that produces a greater inhibitory effect on bacteria, compared to the individual antibacterial effects of the two agents. The purpose of this study was to determine the synergistic effect of anti-bacterial extract of sapodilla fruit (Achras zapota L.) and water gourd (Lagenaria siceraria (Molina) Standl.) extract against Salmonella typhi bacteria. Extraction of sapodilla fruit and water gourd fruit was carried out by maceration method using 96% ethanol (1:10). Determination of the value of the minimum inhibitory concentration (MIC) of anti-bacterial sapodilla manila fruit and water gourd fruit was carried out by the checkerboard assay method using a 96 wells microplate by calculating the Fractional Inhibition Concentration Index (FICI) value. The results showed that the single MIC value of sapodilla manila fruit and water gourd fruit respectively are 50 mg/mL and 100 mg/mL. The interaction between the two is expressed as a Fractional Inhibitory Concentration Index (FICI) with a value of 1.5. The FICI values ​​indicate different antibacterial effects of the combination of sapodilla fruit and water gourd fruit against Salmonella typhi. Keywords: Synergistic, Salmonella typhi, Achras zapota L., Lagenaria siceraria (Molina) Standl., FICI
ANTI-AGING ACTIVITY WITH TYROSINASE INHIBITORS AND ANTIOXIDANTS FROM BADUY OUTER TRIBE PLANTS AS COSMETICS: REVIEW Yuri Pratiwi Utami; Anto Apriyanto; Nurhayani; Agus Firmansyah; Firdaus
JURNAL KATALISATOR Vol. 10 No. 1 (2025): Jurnal Katalisator ( On Progres)
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v10i1.3439

Abstract

Aging is an unavoidable physiological process. The process of premature aging is prevented using natural anti-aging cosmetics derived from plants. Cosmetics can be used as anti-aging products. Therefore, plants can be used as substitutes for anti-aging chemicals with fewer side effects. There are many herbal plants that are empirically used by the Baduy community and have potential as anti-aging agents with tyrosinase inhibitory and antioxidant activities. Evidence of anti-aging activity can be obtained by testing the effects of each herbal plant, which has been conducted by several researchers previously. The purpose of this article is to provide information on which plants have the potential as anti-aging agents for cosmetic raw materials thru a literature review of journals in electronic databases. The results obtained from several plants such as Carica papaya L., Kaempferia galanga, Psidium guajava, Zingiber officinale var. Rubrum, Piper bettle, Caesalpinia sappan L, and Etlingera elatior (Jack) R.M. Sm have tyrosinase inhibitory activity. Orthosiphon stamineus B., Coleus scutellarioides (L.) Benth, and Imperata cylindrica (L) Beauv., the cogongrass plant, use an antioxidant approach as anti-aging. In conclusion, all herbal plants from the Baduy tribe have the potential as raw materials for anti-aging cosmetics
Α-GLUCOSIDASE ENZYME INHIBITOR ACTIVITY OF ETLINGERA ELATIOR LEAF EXTRACT WITH SOLVENT VARIATION Imrawati Imrawati; Yuri Pratiwi Utami; Yuniar Dwi Yanti; Tuti Handayani; Nurzadrina wahyuddin; Zahira Amody; Aulia Debby Pelu; Rahmah Mustarin; Indri Indri
JURNAL KATALISATOR Vol. 10 No. 2 (2025): Jurnal Katalisator, Volume 10 No 2 Oktober 2025
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v10i2.3462

Abstract

Diabetes mellitus (DM) is a chronic metabolic disease characterized by hyperglycemia due to impaired insulin production or utilization. The increasing prevalence of diabetes, especially type 2, is a global concern due to the risk of complications it poses. One approach in treating type 2 diabetes is to inhibit the α-glucosidase enzyme to slow down glucose absorption. This research aims to identify the potential of patikala leaf extract as an α-glucosidase enzyme inhibitor. Using an experimental method with patikala leaf samples collected from Mariri Hamlet, Banyuurip Village, Bone-bone District, North Luwu Regency. Extraction was performed using the maceration method with variations in solvents: 70% ethanol, ethyl acetate, and n-hexane. The α-glucosidase enzyme inhibition activity was measured using a microplate reader and analyzed to determine the IC50 value. From the percentage inhibition data, the IC50 values obtained for 30% ethanol extract of patikala leaves were 351.95 µg/mL, for 70% ethanol extract of patikala leaves were 444.83 µg/mL, for 96% ethanol extract of patikala leaves were 362.27 µg/mL, for ethyl acetate extract of patikala leaves were 163.59 µg/mL, and for n-hexane extract of patikala leaves were 294.90 µg/mL, indicating that patikala leaf extracts with variations in solvent or extraction method exhibited very weak α-glucosidase enzyme inhibition activity. In conclusion, based on the research results obtained, the extract with variations in the solvent or extractant. Patikala leaf extract has an inhibitory activity against the α-glucosidase enzyme, which is categorized as very weak because it has an IC50 value > 100 µg/mL. In comparison, the control (acarbose) is in the weak category with an IC50 value of 50-100 µg/mL.
Co-Authors Abd Rasyid Abd. Halim Umar Abdul Halim Umar Abidin, Hamdayani Lance Abubakar Betan Aditya Yudistira Afni, Fauza Agus Firmansyah Ainun Jariah Ainun Jariah Ainun Jariah Ainun Jariah Ali Djamhuri Andi Paluseri Anto Apriyanto Aprilia Matelda Dwi Kristiyanti Arif Rachman Aripa, Lusyana AS, Indah Meilani Asril Asril Burhan Asril Burhan Astri, Andi Astri Sri Nurul Fardila Astuti Amin Aulia Debby Pelu Benedikta Winne Angela Besse Yuliana Bone, Mahfuzun Burhanuddin Taebe Dwi Yanti, Yuniar Erianto, Fatricia Fadel Ahmad Haris Fadhilla Maryam Fadillah Maryam Fadillah Maryam Fajriansyah Fajriansyah Fhahri Mubarak Firdaus Fitri Andriani, Fitri Fitriyanti Jumaetri Sami Gemini Alam Hamdayani L. A Hamdayani Lance Abidin Hapiwaty, Saldi Hardianti Hardianti, Hardianti HARDIANTO - Heldawati Heldawati Herlina Rante Hilal, Achmad Humang, Rezki Ihsan Imrawati Imrawati Imrawati Imrawati Imrawati Imrawati Imrawati Imrawati Imrawati Imrawati, Imrawati Indah Kadullah Indri Indri Irmayanti Irmayanti, Irmayanti Khairi, Nur Khairuddin Khairuddin L A, Hamdayani Lukman Muslimin Lusianawati, Hayu Mahfuzun Bone Mangosa, Grace Pretty Maria Ulfa Marwati Marwati Mar’atun Jannah, Imrawati, Muzakkir Baitz, Massolo, Selpi Michrun Nisa Mono, Mono Muh Azwar AR Muhammad A.Y. Ardi Mus, Suwahyuni Mustarin, Rahmah Nasution, Ahmad Faisal Nur Aida Kubangun * Nurhayani Nurhedah, Nurhedah Nurhidaya Nurhidaya Nurjannah Bachri Nurjannah Bachri, Nurjannah Nurul Ainun Agustin Nurzadrina Wahyuddin Pannyiwi, Rahmat Prima Astuti Handayani Rahmad Aksa Rahmah Mustarin Rahmah Mustarin Rahmah Mustarin Rahman, Nur Fausia Rahmat, Rezqiqah Aulia Rahmatia Reny Syahruni Risfah Yulianty Rohana Rohana Rosadika Fatimah Rosdiana Rosdiana S, St. Mujahida Safidni, Elvira Saldi Hapiwaty Saparuddin Latu Sari, Lely Meriaya Sarwati, Dewi Sima, Yenny Sri Wahyuni Suhaera Suminar, Saka Surya, Sara Suwahyuni Mus Suwahyuni Mus Suwahyuni Suwahyuni Tuti Handayani Tuti Handayani Tuti Handayani Zainal Wahyu Hendrarti Wahyu Hendrarti Wahyuddin Wahyuddin Wahyuddin Wahyuddin, Nurzadrina Yulia Yusrini Djabir Yuniar Dwi Yanti Zaenal Zaenal, Zaenal Zahira Amody Zainal, Tuti Handayani Zulfahmidah Zulfahmidah