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Journal : JURNAL FARMASIMED (JFM)

Factors Associated with Reduced Blood Glucose Levels in Patients with Diabetes Mellitus: The Role of Oral Antidiabetic Therapyand Dietary Patterns Azrul Zuniarto, Ahmad; Pandanwangi TW, Siti; Deria, Deria
Jurnal FARMASIMED (JFM) Vol 8 No 2 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/as02jb48

Abstract

Background: Diabetes mellitus is a chronic disease that requires proper blood glucose control through appropriate dietary patterns and antidiabetic therapy. Objective: This study aims to analyze the association between dietary patterns and oral antidiabetic therapy with the effectiveness of blood glucose reduction in patients with diabetes mellitus in several health facilities in the Cirebon and Majalengka regions. Methods: This study used an observational cross-sectional design. Data were collected through medical records and the Food Frequency Questionnaire (FFQ). Results and Discussion: The results show that most patients had good dietary patterns, with 53 out of 69 patients (76.8%). In the oral antidiabetic therapy variable, 56 out of 69 patients (81.2%) who used oral antidiabetic drugs showed effective blood glucose reduction. The analysis of dietary patterns indicates that good dietary patterns are associated with a higher likelihood of effective glucose reduction in Cirebon City (OR 0.600; 95% CI: 0.058–6.213), Cirebon Regency (OR 2.500; 95% CI: 0.100–62.605), and Majalengka Regency (OR 0.826; 95% CI: 0.685–0.996). Regarding antidiabetic therapy, the use of Metformin shows a 3.5 times greater likelihood of achieving effective glucose reduction compared to Glibenclamide (OR 3.500; 95% CI: 0.435–28.138). Combination therapy is more favorable in Cirebon Regency (OR 0.100; 95% CI: 0.004–2.504), while in Majalengka Regency, the effectiveness between single and combination therapy is relatively similar (OR 1.167; 95% CI: 0.142–9.586). Conclusion: Overall, this study confirms that good dietary patterns and appropriate oral antidiabetic therapy regimens play an important role in improving the effectiveness of blood glucose control in patients with diabetes mellitus.
Co-Authors , stf1 ., Amirudin Afief, Arief R. Akrom, Akrom Aldhi Bayu Ali, Taufik Amirudin . Andriswana, Dwi Meiria Anjastika, Luky Septiansyah Anna Pradiningsih Aribowo Aribowo ARIS ARIS, ARIS ASEP SUPARMAN Ayuditiawati, Meita Azrul Zuniarto, Ahmad Bachtiar, Arsyad Deni Firmansyah Deria, Deria Dewi, Komala Diana Agustina Didi Rohadi Dzulhijjah, Hawa Eka Putri Wulandari, Eka Putri Farhan Alfawwaz, Azriel Fatmawati, Eva Fauzia, Rizki Rahmah Febriawan, Toyyib Viat Filah Suryana Bahri Fitri Zakiah Haerunnisa, Tita HARYATI, ETI Hasimun, Patonah Husni Mubarok IIN INDAWATI Indah Setyaningsih Jajang Japar Sodik Joharudin, Ade Karphiawati, Aldilla Shalsa Karsidin, Bambang Khalifah, Tria Incky KRISNAWWATI, IKE Lela Sulastri, Lela Lestar, Puri Mardhiyyah, Cut Ainul Meiria A, Dwi Meriska, Caroline Merita Kristianti Minhatul Maula, Ajni Mundzir, O. Ahmad Muwahid, Roni Imron Nabila, Esra Reinanda Nafi'ah, Rahma Nafilah, Nella Nopitasari, Sindi noviani, Adis Nuari, Ris Ayu Nur Rahmi Hidayati, Nur Rahmi Nurhasanah, Sarah Nurkhasanah Nurkhasanah Nurkhasanah NURPATMAWATI, NURPATMAWATI Nurrahma Berlian, Febia Oktaviani, Dian Regar, Dhea Novakinanda Rizki Rahmah Fauzia Rubihatlan, Encis Sabarudin, Cecep Salafi, Akil Septiansyah, Luky Setriyadi, Dedy Sri Virgianti, Deby Subagja Subagja, Subagja Sugiharto, Anto Suharmono, Soni Sulistiorini Indriaty Sunandi, Retno Tresno Sundari, Retno T Sundari, Retno Tresno Titiek Suhardi Haripurnomo Kushadiwijaya Hidayati Tsai, Mei Ling Utami, Amanda Dwi Wahyuni, Yenny Sri Widianingsih, Nining Wiguna, Taufik Marta Yani, Dosi Ahmad Zakiah, Fitri Zanki, Alfriani Melia Zuniarto, Ahmad Azrul