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All Journal Jurnal Respirologi Indonesia Jurnal Biomedika dan Kesehatan Jurnal Respirasi (JR) PREPOTIF : Jurnal Kesehatan Masyarakat JOURNAL LA MEDIHEALTICO MAHESA : Malahayati Health Student Journal Wal'afiat Hospital Journal INDONESIAN JOURNAL OF HEALTH Formosa Journal of Science and Technology (FJST) Jurnal Sehat Indonesia (JUSINDO) Innovative: Journal Of Social Science Research WAL'AFIAT HOSPITAL JOURNAL Journal Of Medicine And Health Sciences (Medisci)
Wiriansya, Edward Pandu
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Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Terapi Non Farmakologi dalam Pengendalian Tekanan Darah pada Pasien Hipertensi Putra, Mardhiyanto Azhary; Nurhikmawati, Nurhikmawati; Khalid, Nur Fadhillah; Wiriansya, Edward Pandu; Arifuddin, Abdul Mubdi Ardiansar
Wal'afiat Hospital Journal Vol 5 No 1 (2024): Wal'afiat Hospital Journal
Publisher : Rumah Sakit Ibnu Sina, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/whj.v5i1.130

Abstract

Changes in the pattern of communicable diseases to non-communicable diseases are classified as non-communicable diseases that do not cause scanning effects on other people and are a major factor in disorders of the blood vessels and chronic kidney disease, namely hypertension. Consumption of antihypertensive drugs continuously for a long time is not controlled and can increase the occurrence of Drug Related Problems (DRP). DRP is an effect experienced by the patient due to the involvement of the choice of treatment therapy used by the patient and is actually able to have an impact on the patient's condition such as non-adherence to drug consumption, drug side effects, or allergies that arise due to the drug consumed. This is proof that other alternative therapies are needed that are able to reduce the risk of dependence on drugs in maintaining the quality of life of people with hypertension, so the authors made a Literature Review on "Non-Pharmacological Therapy in Controlling Blood Pressure in Hypertensive Patients". To find out non-pharmacological therapy in controlling blood pressure in hypertensive patients. This type of research uses Literature Review with a Narrative Review approach. Where the database used is Clinical Key, Google Scholar, NCBI, textbook, MedScape, WHO, and data from the Indonesian Ministry of Health. Based on a Literature Review of the 12 articles analyzed in the study, it was stated that non- pharmacological therapy for hypertension is proven to be an alternative to lowering blood pressure through various means such as lifestyle interventions, biofeedback techniques, foot reflexology, slow deep breathing exercises, consumption various herbal plants to reduce the side effects of consuming synthetic drugs. Non-pharmacological therapy for hypertensive patients can reduce blood pressure with various methods.
Hubungan Kebiasaan Merokok dengan Penyakit ISPA pada Pasien di Puskesmas Mandai Kabupaten Maros N.H, M. Tajussubky; Rijal, Syamsu; Wiriansya, Edward Pandu
Wal'afiat Hospital Journal Vol 5 No 1 (2024): Wal'afiat Hospital Journal
Publisher : Rumah Sakit Ibnu Sina, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/whj.v5i1.133

Abstract

This study aims to analyze the relationship between smoking habits and the incidence of Acute Respiratory Tract Infection (ARI) in patients at Puskesmas Mandai, Maros Regency. Using quantitative methods with a correlation analytic approach and cross-sectional design, data were collected from 105 respondents from September to October 2022. The results showed that most ARI patients were children under 10 years old (51.4%), with a higher prevalence in males (58.1%). In terms of smoking status, all secondary smokers (50.5%) and the majority of tertiary smokers (37.1%) experienced ARI, while only 7.6% of primary smokers experienced ARI. Statistical analysis showed a significant association between smoking and ARI incidence (p-value less than 0.05). This finding confirms that smoking, especially in the family environment, contributes significantly to the increased incidence of ARI. It is recommended that Puskesmas Mandai conduct socialization about the dangers of smoking and further research with more respondents for more specific and comprehensive results.
Hubungan Efek Samping Obat Anti Tuberkulosis (OAT) dengan Kepatuhan Berobat Pada Pasien Tuberkulosis di Puskesmas Jongaya Makassar Andira, Besse Putri; Dahliah, Dahliah; Wiriansya, Edward Pandu; Irwan, Andi Alamanda; Hamzah, Pratiwi Nasir
Wal'afiat Hospital Journal Vol 5 No 1 (2024): Wal'afiat Hospital Journal
Publisher : Rumah Sakit Ibnu Sina, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/whj.v5i1.134

Abstract

Tuberculosis is a direct infectious disease caused by Mycobacterium tuberculosis, which mainly affects the lungs and is transmitted through airborne droplets or sputum from TB patients with positive BTA. The morbidity and mortality of tuberculosis is a serious problem, mainly due to the side effects of Anti-Tuberculosis Drugs (OAT). This study aims to determine the relationship between OAT side effects and treatment compliance of pulmonary tuberculosis patients at the Jongaya Makassar Health Center. This study used a cross-sectional approach with quantitative methods, involving 49 respondents selected using the Slovin formula. The research instruments were OAT side effects questionnaire and treatment compliance questionnaire, with data analysis conducted univariately and bivariately using Chi Square test. The results showed that most respondents experienced low side effects and had a high level of treatment compliance. In conclusion, there is a significant relationship between OAT side effects and treatment compliance of tuberculosis patients at the Jongaya Makassar Health Center, where the lower the perceived side effects, the higher the level of treatment compliance.
Hubungan Penerapan Perilaku Hidup Bersih dan Sehat (PHBS) Keluarga terhadap Kejadian Infeksi Saluran Pernapasan Akut (ISPA) pada Balita di Puskesmas Mandai Kabupaten Maros Aprilia, Salsabila Tirta; Rijal, Syamsu; Wiriansya, Edward Pandu; Vitayani, Sri; Nasruddin, Hermiaty
Wal'afiat Hospital Journal Vol 5 No 1 (2024): Wal'afiat Hospital Journal
Publisher : Rumah Sakit Ibnu Sina, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/whj.v5i1.135

Abstract

This study aims to explore the relationship between the implementation of clean and healthy living behaviors (PHBS) in the family with the incidence of Acute Respiratory Infections (ARI) in toddlers at Puskesmas Mandai, Maros Regency. Using a quantitative approach with a correlation analytic method, this study involved 58 toddlers aged 0-5 years who were diagnosed with ARI. The results showed that 58.6% of respondents were male, with the largest age group 0-12 months (25.9%). 74.1% of the toddlers were not exclusively breastfed, and 80.9% were underweight. In addition, 75.7% of respondents did not have the habit of washing hands with soap, and 94.8% lived in an environment with active smokers. Bivariate analysis showed a significant association between the PHBS variables and the incidence of ARI, with P values less than 0.05 for all variables. These results suggest that the implementation of exclusive breastfeeding, routine weighing of toddlers, hand washing with soap, and not smoking in the house play an important role in reducing the incidence of ARI. Therefore, health centers are advised to increase the socialization of PHBS and education about the dangers of smoking, as well as encourage the community to apply clean living behavior in everyday life. This study is expected to be the basis for improving health programs at Puskesmas Mandai and increasing public awareness about the importance of PHBS in preventing ARI.
Analysis of the Relationship between Pulmonary Hypertension and Tuberculosis Patients at RS Ibnu Sina Makassar January - June 2023 Alfian, Dwi Hermin; Wiriansya, Edward Pandu; Ardiyanto, Ardiyanto; Arif, Muhammad; Anggita, Dwi; Ginayah, Mir’atul
Formosa Journal of Science and Technology Vol. 3 No. 8 (2024): August 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjst.v3i8.10079

Abstract

Pulmonary hypertension (PAH), seen in 20%-40% of chronic respiratory diseases, is linked to the severity of these conditions. Tuberculosis, a bacterial infection causing lung damage and impaired function, can contribute to this increased blood pressure in the pulmonary arteries, complicating patient outcomes by worsening both conditions. This study used an analytical observational method with a cross-sectional approach, measuring independent and dependent variables simultaneously at a single point in time. It focused on analyzing the relationship between pulmonary hypertension and pulmonary tuberculosis in patients. The study found that most respondents were aged 51-70 years, with no significant link between age or gender and hypertension (P-values=0.091 and 0.655, respectively). Light smoking was significantly associated with hypertension (P-value=0.001), while nutritional status was not (P-value=0.332). Significant relationships were found between blood pressure (P-value=0.002) and spirometry results (P-value=0.000) with hypertension. Thus, blood pressure, smoking habits, and spirometry results were key factors influencing pulmonary hypertension in the 60 patients studied. There is a significant relationship between Pulmonary Hypertension and Tuberculosis patients at Ibnu Sina Hospital, Makassar, January - June 2023.
Hubungan X- Ray dan CD4 Viral Load Pada Pasien Tubercolosis HIV Andira, Besse Putri; Wiriansya, Edward Pandu; Rompegading, Andi
Jurnal Sehat Indonesia (JUSINDO) Vol. 6 No. 02 (2024): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jsi.v6i02.100

Abstract

Perjuangan melawan virus Human Immunodeficiency Virus (HIV) memerlukan penanganan terhadap kendala-kendala terkait diagnosis tuberkulosis (TB) pada pasien yang terinfeksi kedua penyakit ini (HIV-TB). Rontgen dada menjadi instrumen kunci untuk menilai keberadaan tuberkulosis pada individu yang mengalami koinfeksi HIV-TB. Tujuan penelitian ini adalah untuk mengkaji hubungan antara X-ray dan CD4 viral load pada pasien TB HIV/AIDS. Penelitian ini menggunakan metode penelitian literature review. Teknik pengumpulan data pada penelitian ini adalah studi pustaka yang diperoleh melalui Google Scholar dan PubMed. Data yang telah terkumpul kemudian dianalisis menggunakan tiga tahapan yakni reduksi data, penyajian data dan penarikan kesimpulan. Hasil penelitian menunjukan bahwa jumlah CD4 berhubungan dengan manifestasi klinis pasien HIV yang bisa dilihat dari gambaran radiologis, sehingga dapat digunakan dalam mempercepat penegakkan diagnosis. Selain itu, terdapat hubungan antara pola sinar X dengan jumlah CD4 pada pasien HIV-TB, yang dapat memberikan informasi penting terkait dengan status imunologis pasien. Penelitian juga menunjukkan bahwa terdapat korelasi antara jumlah CD4+ dan bentuk tuberkulosis pada pasien TB-HIV.
Efektivitas Pemberian Madu Hutan (Apis Dorsata) dalam Mengatasi Infeksi Klebsiella Pneumoniae pada Mencit ( Mus Musculus) Musa, Muh. Muflih Usman; Wiriansya, Edward Pandu; Dwimartyono, Fendy; Mangarengi, Yusriani; Khalid, Nurfadhillah; Ahmad, Izhar Fitrah; Adrian, Adrian; Faisal, Fathir; Fazdlurrahman, Fazdlurrahman; Ilham, Muhammad
MAHESA : Malahayati Health Student Journal Vol 5, No 11 (2025): Volume 5 Nomor 11 (2025)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v5i11.19657

Abstract

ABSTRACT Nosocomial infections, especially those caused by Klebsiella pneumoniae bacteria, are a significant global health problem. The increasing antibiotic resistance encourages the search for alternative therapies, one of which is through the use of natural ingredients such as honey. Honey, especially Apis dorsata wild honey, is known to have antibacterial properties that can inhibit bacterial growth. To evaluate the effectiveness of giving forest honey (Apis dorsata) based on preventive, curative and supportive groups in treating Klebsiella pneumoniae infections in mice. This research uses a quasi experimental post-test method. A total of 30 mice were divided into 5 treatment groups. The test carried out was the Colony Number Distribution Test, then the Normality Test, after finding that the samples were not normally distributed, we chose the Kruskal Wallis Non-Parametric Test and the Mann-Whitney Test.Of the five groups studied, the intervention in the group given forest honey (Apis dorsata) combined with the antibiotic ceftriaxone as well as in the group given first forest honey (Apis dorsata) showed effective results (P<0.05) while the other groups did not show results. effective (P>0.05). Based on research, it was explained that giving forest honey (Apis dorsata) was effective as a preventive and supportive group, but was not effective as a curative group in treating Klebsiella pneumoniae infections in mice. Keywords: Forest Honey (Apis Dorsata), Klebsiella Pneumoniae Infection, Mice (Mus Musculus).  ABSTRAK Infeksi nosokomial, terutama yang disebabkan oleh bakteri Klebsiella pneumoniae, merupakan masalah kesehatan global yang signifikan. Meningkatnya resistensi antibiotik mendorong pencarian alternatif terapi, salah satunya melalui penggunaan bahan alami seperti madu. Madu, khususnya madu hutan Apis dorsata, diketahui memiliki sifat antibakteri yang dapat menghambat pertumbuhan bakteri. Untuk mengevaluasi efektivitas pemberian madu hutan (Apis dorsata) berdasarkan kelompok upaya preventif, kuratif serta supportif dalam mengatasi infeksi Klebsiella pneumoniae pada mencit. Penelitian ini menggunakan metode quasi experimental post-test. Sebanyak 30 ekor mencit dibagi menjadi 5 kelompok perlakuan. Pengujian yang dilakukan adalah Uji Distribusi Jumlah Koloni, lalu kemudian Uji Normalitas, setelah didapatkan sampel tidak terdistribusi normal sehingga kami memilih Uji Non Parametrik Kruskal Wallis serta Uji  Mann-Whitney. Dari lima kelompok yang diteliti, intervensi pada kelompok pemberian madu hutan (Apis dorsata) yang dikombinasi dengan antibiotik ceftriaxone juga pada kelompok yang diberikan terlebih dahulu madu hutan (Apis dorsata) menunjukkan hasil yang efektif (P<0.05) sedangkan kelompok yang lain tidak menunjukkan hasil yang efektif (P>0.05). Berdasarkan penelitian, dijelaskan bahwa pemberian madu hutan (Apis dorsata) efektif sebagai kelompok preventif dan  supportif, namun tidak efektif sebagai kelompok kuratif dalam mengatasi infeksi Klebsiella pneumoniae pada mencit. Kata Kunci: Madu Hutan (Apis Dorsata), Infeksi Klebsiella Pneumoniae, Mencit (Mus Musculus).
Persistent Air Leak Anggita, Dwi; Wiriansya, Edward Pandu; Santoso, Arif; Putrawan, Harry Azka
Jurnal Respirologi Indonesia Vol 44 No 2 (2024)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v44i2.432

Abstract

In cases of pneumothorax in the chest tube, the presence of air in the pleural cavity that lasts more than 5 to 7 days can be suspected as a persistent air leak (PAL), especially if an increased amount of air is obtained accompanied by the appearance of bubbles in the water seal drainage (WSD) system. This is the most common complication after surgery (8–26%), although it can be primary spontaneous pneumothorax (PSP) (26%) or secondary spontaneous pneumothorax (SSP) (39%). One condition that often causes difficulties in PAL therapy is infection due to direct contact with the fistula. The presence of PAL is associated with higher morbidity and mortality, prolonged chest tube inserted, and longer hospitalization. Observations of air production in PAL are expected to occur spontaneously within 4 days, if the leak persists, pleurodesis is recommended. If it was possible, surgery is needed to close the leak. Bronchoscopy treatment is only recommended in special circumstances where surgery is contraindicated or the patient refuses the surgical procedure.
Vitamin E Supplementation and Its Impact on Pulmonary Tuberculosis Treatment Outcomes: A Systematic Review Basir, Adhelia Zalsabilah; Wiriansya, Edward Pandu; Damopolii, Suciati; Hasan, Hasan; Kanang, Indah Lestari Daeng
Journal La Medihealtico Vol. 6 No. 6 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i6.2776

Abstract

Pulmonary tuberculosis remains a global health problem, and antioxidant deficiencies such as vitamin E contribute to increased oxidative stress in patients. The aim of this study was to assess the effect of vitamin E supplementation on the effectiveness of pulmonary tuberculosis treatment through a systematic review based on PRISMA 2020 guidelines. This systematic review included clinical and observational studies investigating the relationship between vitamin E and pulmonary tuberculosis. Literature searches were conducted in PubMed and Google Scholar (2008–2021) using the keywords “Vitamin E,” “Tuberculosis,” and “Lung.” Methodological quality was assessed using the JBI Checklist and Cochrane RoB2. The process was carried out at the Faculty of Medicine, Muslim University of Indonesia, Makassar, from March to August 2024. Secondary data from published studies were used; therefore, ethical approval was not required. Six studies met the inclusion criteria, consisting of two randomized controlled trials, two in vitro studies, one case–control study, and one cross-sectional study. The synthesis results showed that vitamin E supplementation consistently reduced oxidative stress, as indicated by a significant decrease in malondialdehyde (MDA) levels and an increase in enzyme activity. In addition, vitamin E improved inflammatory status through reduced C-reactive protein (CRP) levels and increased serum leptin, as well as enhanced cellular immune responses through elevated IL-2 and IFN-γ levels. Overall, vitamin E supplementation contributed to improved treatment effectiveness and quality of life in patients with pulmonary tuberculosis.Vitamin E supplementation has potential as an adjuvant therapy that enhances the effectiveness of pulmonary tuberculosis treatment through antioxidant and immunomodulatory mechanisms.
Obstructive Sleep Apnea Risk, Body Fat, and BMI in Pulmonary Tuberculosis Patients Jumaide, Nurul Isnaeni; Wiriansya, Edward Pandu; Karim, Marzelina; Safitri, Asrini; Pratama, Ahmad Ardhani
Jurnal Medisci Vol 3 No 4 (2026): Vol 3 No 4 February 2026
Publisher : Ann Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62885/medisci.v3i4.1070

Abstract

Background: Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder significantly associated with body composition abnormalities. Pulmonary tuberculosis (TB) causes structural lung damage that may predispose patients to sleep disturbances, yet the relationship between OSA and body composition in TB populations remains inadequately explored. Aim: This study aimed to investigate the association between OSA severity and body composition measures including total body fat, visceral fat, subcutaneous fat, and body mass index (BMI) among pulmonary TB patients. Methods: A cross-sectional analytical observational study was conducted at RS Ibnu Sina YW-UMI Makassar from August to November 2025. Eighty-five pulmonary TB patients were selected through purposive sampling. OSA risk was assessed using the STOP-BANG questionnaire, while body composition was measured using bioelectrical impedance analysis. Chi-square tests were performed to examine associations between variables with significance set at p<0.05. Results: Significant associations were found between OSA severity and all body composition parameters: total body fat (p=0.004), visceral fat (p=0.000), subcutaneous fat (p=0.005), and BMI (p=0.000). Severe OSA showed highest prevalence of very high total body fat (46.4%), elevated visceral fat (60.7%), high subcutaneous fat (57.1%), and obesity grade 1 (35.7%). Moderate OSA occurred predominantly in underweight patients (50.0%), revealing a U-shaped BMI-OSA relationship. Conclusions: Visceral fat demonstrated the strongest association with OSA severity in pulmonary TB patients. Comprehensive body composition assessment provides superior clinical utility compared to BMI alone for OSA risk stratification. Implementation. These findings support integrating body composition monitoring into TB management protocols and provide foundation for personalized interventions addressing both infectious disease treatment and metabolic health optimization
Co-Authors Abdi, Dian Amalia Abdi, Dian Amelia Abdullah, Rezky Putri Indarwati Adrian Adrian Ahmad Ardhani Pratama Ahmad, Izhar Fitrah Alfian, Dwi Hermin Amrizal Muchtar Andira, Besse Putri Anggita, Dwi Anshary, Suci Noviyanah Aprilia, Salsabila Tirta Ardiyanto Ardiyanto Arief, Erwin Arif Santoso Arifin, Fenty Nisa Arifuddin, Abdul Mubdi Ardiansar Azis, Uyuni Basir, Adhelia Zalsabilah Basri, Rezky Pratiwi Lambang Cantika Carmelia, Andi Dila Dahlia Dahlia Dahliah, Dahliah Damopolii, Suciati Faisal, Fathir Faisal, M. Fathir Fausiah, Andi Arista Fazdlurrahman, Fazdlurrahman Fendy Dwimartyono Ginayah, Mir’atul Hamzah, Firmansyah Hamzah, Pratiwi Nasir Haring, Andi Muh. Batara Sakti Hasan Hasan Hidayat, Lujna Adharani Ikram, Dzul Irmayanti Irmayanti, Irmayanti Irna Diyana Kartika Irwan, Andi Alamanda Isra Yustika, Aulia Jumaide, Nurul Isnaeni K, Irna Diyana Kartika Kanang, Indah Lestari Daeng Karim, Marzelina Khalid, Nur Fadhillah Khalid, Nurfadhillah Mangarengi, Yusriani Masdipa, Andi Muchsin, Achmad Harun Muhammad Arif Muhammad Fakhri Muhammad Ilham Mulyadi, Farah Ekawati Musa, Muh. Muflih Usman N.H, M. Tajussubky N.H., M. Tajussubky Nasruddin, Hermiaty Nurhikmawati, Nurhikmawati Nurmadilla, Nesyana Pratama, Muh. Khairul Putra, Mardhiyanto Azhary Putrawan, Harry Azka Qarinah, Maryam Rompegading, Andi Safitri, Asrini Sodiqah, Yani Sommeng, Faisal Sri Vitayani Sugeng Santoso Syamsu Rijal Syamsuddin, Saidah Syarkawi, M. Fathir Faisal Thahir Tabri, Nur Ahmad Takahasi, Tanty Febriany Tulak, Pither Sandy Usman, Muh. Muflih Wardani, Emy Yanti, Andi Kartini Eka Zulfitriani Murfat