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Antibacterial Screening of Mangrove Extract Library Showed Potential Activity against Escherichia coli and Staphylococcus aureus Audah, Kholis Abdurachim; Batubara, Razethy; Julkipli, Julkipli; Wijaya, Elza; Kurniawaty, Evi; Batubara, Irmanida
Journal of Tropical Life Science Vol 10, No 2 (2020)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.10.02.03

Abstract

Humans are at a continuous battle against different types of diseases, so that extraordinary effort to accelerate drug discovery has become a necessity. Indonesian biodiversity is abundant natural resources that can be utilized as potential drug sources. Mangroves are among potential plant medicines that grow nearly at all Indonesian coastlines. The aim of this study was to evaluate the potential of mangrove extracts (extract library) as antibacterial agents. In this study, eight mangroves species with 16 samples from different parts of the plants such as leaf, bark or root were collected. Four types of solvents with different polarity, namely water, ethanol, ethyl acetate and hexane were used in maceration of samples producing 64 extracts. Disk diffusion method was used for antibacterial screening using five bacterial strains. There were 37 extracts showed antibacterial potential with the lowest and the highest inhibition indexes were 0.0283 and 1.8983, respectively. The highest inhibition index was recorded for ethyl acetate extract of Bruguiera gymnorrhiza root (BgR (Ea)) against Escherichia coli. The second highest inhibition index was 0.7867 recorded water extract of Avicennia marina leaf (AmL (A)) against Staphylococcus aureus. Almost all of extract showed saponin and tannin in considerable amount. This supported the data that mangrove extracts were potential as antibacterial agents.
Co-Authors Akib, Salsabila Nadhifa Alvinasyrah, Alvinasyrah Andriani, Silvia Anita Febrina, Anita Annisa Fath Ari Irawan Asep Sukohar Audah, Kholis A. Audah, Kholis Abdurachim Ayu S, Putu Ristyaning Bainah Sari Dewi Balqis, Aurelia Corrinna Batubara, Razethy Berawi, Khairunisa Daulay, Suryani Agustina Dewi Nur Fiana Din, Bahesty Cut Nyak Dwi Indria Anggraini Elidiya, Anggun Ersa, Rakhmigasti Citra Ety Apriliana Hanna Mutiara, Hanna Hendri Busman Iffa Afiqa Khairani Intan Kusumaningtyas Intanri Kurniati Irmanida Batubara Julkipli Julkipli, Julkipli Justiani, Andinni Aurellia Karima, Nisa Kaskoyo, Hari Khairun Nisa Khairun Nisa Kurniati, Intanti Mallarangeng, Andi Nafisah Tendri Adjeng Muhammad Aditya, Muhammad Muhammad Arif Muhammad Maulana Muhammad Ricky Ramadhian Nuning Nurcahyani Nuriah, Nuriah Nurul Islamy Oktadoni Saputra, Oktadoni Oktafany, Oktafany Oktoba, Zulpakor Poty, Pitha Maykania Pramudyawati, Yustika Puspa, Egita Windrianatama Rahmansia, Soraya Rahmayani, Fidha Rasmi Zakiah Oktarlina Reni Zuraida Rini, Sandra Risti Graharti Rossa, Putri Emylia Sahroni, Mizan Samsul Bakri Sandro, Mario Sangging, Putu Ristyaning Ayu Setyadi, Yudha Putra Situmorang, Ephraim Matthew Sebastian Situmorang, Ezra Winandi Soraya Rahmanisa Suharyani Suharyani Susianti Susianti Sutarto Sutarto Sutyarso Sutyarso Sutyarso Syarif, Muhammad Reza Syazili Mustofa Taruna, Achmad Tiwuk Susantiningsih Tri Umiana Soleha Wijaya, Elza Winda Trijayanthi Utama, Winda Trijayanthi Wiwi Febriani Wulan, Anggraini Janar Yogi Catur Putra