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All Journal Biospecies Jurnal Kedokteran Brawijaya JIMKesmas (Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat) BERITA BIOLOGI The Indonesian Biomedical Journal Lantanida Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Kesehatan Komunitas Window of Health : Jurnal Kesehatan Indonesian Journal of Medicine Jambura Journal of Health Sciences and Research Journal Health & Science : Gorontalo Journal Health and Science Community Jurnal Kesehatan Poltekita : Jurnal Ilmu Kesehatan Jurnal Keperawatan Priority Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Prima Medika Sains An-Nadaa: Jurnal Kesehatan Masyarakat AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Jurnal Inovasi Pendidikan dan Sains Jurnal Penelitian Pendidikan, Psikologi Dan Kesehatan (J-P3K) Jurnal Ilmiah METADATA Eureka Herba Indonesia Jurnal Kesehatan Tambusai MAHESA : Malahayati Health Student Journal Journal of Multidisciplinary Applied Natural Science Interdisciplinary Social Studies Jurnal EduHealth Journal of Current Health Sciences International Journal of Islamic Education, Research and Multiculturalism (IJIERM) Jurnal Locus Penelitian dan Pengabdian Jurnal Sains dan Teknologi Buletin Kedokteran dan Kesehatan Prima Pharmaceutical Sciences and Research (PSR) International Journal of Health and Pharmaceutical (IJHP) International Journal of Science and Environment Eduvest - Journal of Universal Studies Journal of Pharmaceutical and Sciences. Blantika : Multidisciplinary Journal Malahayati International Journal of Nursing and Health Science
Chiuman, Linda
Universitas Prima Indonesia
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Description of Hematological Parameters and Severity Levels of COVID-19 Patients and Disease Progression at Royal Prima Hospital, Medan, North Sumatera, Indonesia Azah, Yunita Wannur; Novalinda Ginting, Chrismis; Chiuman, Linda; Ferdinand, Sahna
Indonesian Journal of Medicine Vol. 8 No. 4 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.8.4.690

Abstract

Background: The severity of COVID-19 can be evaluated by checking several routine hematological parameters. Routine hematology examinations have an important role in early detection, diagnosis, disease management and disease progression. This study aims to determine the relationship between hematological parameters and disease progression and severity in COVID-19 patients. Subjects and Method: This was a cross sectional study conducted at Royal Prima Hospital, Medan, North Sumatera, Indonesia, from January to February 2022. A total of 93 patients who had confirmed COVID-19 were selected using a simple random sampling technique according to the inclusion and exclusion criteria. The research was The dependent variables of this research were disease progression and severity of COVID-19 patients. The independent variables are hematological parameters based on hospital medical record data. Data analysis used the Chi-Square test and logistic regression. Results: 75 people (80.6%) COVID-19 sufferers had severe disease. NLR and D-dimer levels were significantly related to disease progression in COVID-19 sufferers (p<0.05). Leukocyte, lymphocyte, NLR, CRP, D-dimer levels are related to the severity of COVID-19 sufferers (p<0.05). Leukocyte levels have the strongest relationship with the severity of COVID-19 with an OR value of 1.798. Conclusion: NLR and D-dimer levels are significantly related to disease progression and leukocyte. Lymphocyte, NLR, CRP, D-dimer levels are related to the severity of COVID-19 sufferers.
Hubungan Edukasi Dokter Keluarga Dan Pemberdayaan Keluarga Dengan Kemampuan Keluarga Melakukan Self Care Pada Pasien Diabetes Di Klinik Pratama Dandy Fahlevy, Ridho; Nasution, Ali Napiah; Chiuman, Linda
JURNAL PENELITIAN PENDIDIKAN, PSIKOLOGI DAN KESEHATAN (J-P3K) Vol 6, No 1 (2025): J-P3K
Publisher : Yayasan Mata Pena Madani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51849/j-p3k.v6i1.687

Abstract

Penelitian ini bertujuan untuk menganalisis hubungan antara edukasi dokter keluarga dan pemberdayaan keluarga dengan kemampuan keluarga dalam melakukan self-care pada pasien diabetes di Klinik Pratama Dandy. Desain penelitian yang digunakan adalah deskriptif korelatif dengan pendekatan cross-sectional. Populasi penelitian terdiri dari keluarga pasien dengan diagnosis diabetes mellitus, dengan jumlah sampel sebanyak 55 orang yang diperoleh melalui teknik total sampling, Penelitian ini dilaksanakan pada Agustus 2024. Analisis data dilakukan menggunakan aplikasi SPSS 16.0 dengan uji korelasi Chi-Square.Hasil penelitian menunjukkan bahwa sebagian besar responden menerima edukasi dokter keluarga dalam kategori baik, yaitu sebanyak 31 orang (56,4%). Kemampuan keluarga dalam melakukan self-care juga tergolong baik pada 32 responden (58,2%). Selain itu, pemberdayaan keluarga dalam merawat pasien diabetes berada dalam kategori baik pada 41 responden (74,5%). Uji statistik menunjukkan adanya hubungan yang signifikan antara edukasi dokter keluarga dengan pemberdayaan keluarga (p = 0,000) serta antara kemampuan keluarga dalam self-care dengan pemberdayaan keluarga (p = 0,000). Penelitian ini merekomendasikan agar penelitian selanjutnya menggunakan metode yang lebih komprehensif, seperti observasi dan wawancara, untuk mendapatkan data yang lebih mendalam
Comparison of Neutrofil-Lymphocyte Ratio to Severity of Stroke Ischemic Based of Vascular Territory Assessed By Ct-Scan Stanliko, Stanliko; Tandiono, Michelle; Chiuman, Linda
Blantika: Multidisciplinary Journal Vol. 2 No. 4 (2024): Reguler Issue
Publisher : PT. Publikasiku Academic Solution

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57096/blantika.v2i4.129

Abstract

Diagnosing severity of the stroke requires a NIHSS score which is a graded neurological examination. However, despite its successes, there are problems with the NIHSS. The scale contains items with poor reliability and has been criticized for its redundancy and complexity may not capture the full range of stroke severity, particularly in those with very mild or severe symptoms. Over the last 10 years, the evaluation of the NLR as an emerging marker of diseases has become a compelling field of bio-medical research. However, the value of NLR in predicting the poor prognosis of stroke patients is still controversial. Patients of stroke ischemic from July to December 2023 at Royal Prima Hospital were studied to analyze the correlation between NLR to severity of stroke regarding vascular territory. Our investigation reveals no correlation between those two variablesation between those two variables.
Investigation of Potential Molecular Targets of Zanthoxylum acanthopodium in Ovarian Cancer Using Network Pharmacology Assessments Wijaya, Johanna Fransiska; Chiuman, Linda; Syahputra, Hariyadi Dharmawan; Kaban, Vera Estefania; Razoki, Razoki; Ginting, Chrismis Novalinda; Iksen, Iksen
Journal of Multidisciplinary Applied Natural Science Vol. 5 No. 2 (2025): Journal of Multidisciplinary Applied Natural Science
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/jmans.2774-3047.268

Abstract

Ovarian cancer is a serious disease that affects the ovaries, and its early detection is challenging due to vague symptoms often dismissed as minor ailments. Currently, natural sources have gained attention for their potential role in anticancer treatment. This study aimed to utilize network pharmacology to explore the potential targets and mechanisms of Zanthoxylum acanthopodium in the treatment of ovarian cancer. This study utilized the KNApSAcK and Swiss Target Prediction to identify active compounds and target genes. Additionally, ovarian cancer-specific target genes were sourced from the GEO database. To identify possible key target genes, the network interaction between protein-protein using the STRING database and visualized them in Cytoscape. Subsequent analysis using Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways enabled us to focus on primary therapeutic targets. Our investigation into Zanthoxylum acanthopodium revealed 10 active compounds that pass Lipinski rule of five and oral bioavailability with acceptable pharmacokinetic profiles, 88 therapeutic targets, and identified 5 hub genes: SRC, CCNB2, MMP9, PTGS2, and PTPRC, which are strongly associated with ovarian cancer progression. Pathway enrichment analysis highlighted several pathways significantly related to the pathogenesis of ovarian cancer. This study elucidates the therapeutic potential and mechanisms of action of Z. acanthopodium as a promising candidate for ovarian cancer treatment. However, further research, including both in vitro and in vivo studies, is necessary to understand its molecular mechanisms comprehensively.
Determinant Analysis of Hypertension in Type 2 Diabetes Mellitus Patients: A Cross-Sectional Study in Medan, North Sumatera, Indonesia Tjendera, Mariaman; Gusbakti; Chiuman, Linda; Mukti, Ade Indra; Sartika, Dewi
Indonesian Journal of Medicine Vol. 10 No. 2 (2025)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2025.10.2.831

Abstract

Background: Type 2 diabetes mellitus (T2DM) and hypertension are two chronic conditions that frequently co-occur and pose a significant health burden. At Padang Bulan Primary Healthcare Center in Medan, out of 260 Prolanis participants, 117 T2DM patients sought treatment, and 90 of them were diagnosed with hypertension. This study aimed to analyze the determinants of hypertension in T2DM patients receiving care at Padang Bulan Primary Healthcare Center in Medan. Subjects and Method: An analytical cross-sectional study was conducted on 100 T2DM patients selected through consecutive sampling. Data were collected using structured question¬naire, anthropometric measurement, and blood pressure and blood glucose examinations. The variables studied included sociodemographic characteristics (gender, education, occupation, marital status) and clinical characteristics (body mass index, duration of T2DM, blood glucose levels, family history). Data analysis was performed using Chi-square test. Results: The majority of respondents were women (62%), highly educated (79%), and obese (87%). The prevalence of hypertension in T2DM patients was notably high (>70%) across all groups. However, bivariate analysis showed no statistically significant relationship between any of the studied variables and the incidence of hypertension (p>0.05). Conclusion: There was no significant relationship between sociodemographic and clinical factors with the incidence of hypertension in T2DM patients. Nevertheless, the high prevalence of hypertension indicates the importance of a comprehensive approach in managing both conditions
Efektifitas Ekstrak Daun Pepaya (Carica Papaya L) Terhadap Kadar MDA Dan SOD pada Tikus (Rattus Norvegicus) yang Diberi Aktivitas Fisik Tambunan, Ridhona; Girsang, Ermi; Chiuman, Linda
JURNAL PENELITIAN PENDIDIKAN, PSIKOLOGI DAN KESEHATAN (J-P3K) Vol 6, No 2 (2025): J-P3K
Publisher : Yayasan Mata Pena Madani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51849/j-p3k.v6i2.766

Abstract

Radikal bebas yang terdapat di dalam tubuh dapat dinetralisir dengan antioksidan endogen. Namun jika produksi radikal bebas melebihi kemampuan antioksidan endogen berpotensial menyebabkan kerusakan sel. Oleh karena itu tubuh memerlukan pasokan antioksidan dari luar tubuh yang lebih dikenal dengan antioksidan eksogen. Hasil analisis fitokimia menunjukkan daun pepaya mengandung senyawa antioksidan yang diyakini dapat merangsang terbentuknya antioksidan endogen. Adapun tujuan penelitian ini adalah menganalisis pemberian ekstrak daun pepaya (Carica Papaya L) terhadap kadar MDA dan SOD pada tikus galur wistar (Rattus norvegicus) yang diberi aktivitas fisik. Penelitian ini menggunakan jenis penelitian true experimental dengan post test only randomized control group design menggunakan tikus putih jantan dengan perlakuan aktivitas fisik sebagai subyek penelitian. Hasil penelitian menunjukkan terdapat perbedaan yang signifikan kadar MDA dan SOD tikus (Rattus norvegicus) dengan aktifitas fisik berlebih setelah pemberian ekstrak daun pepaya (Carica Papaya L dan dosis dari ekstrak daun pepaya 750 mg/200gBB adalah dosis terbaik dalam menurunkan kadar MDA dan meningkatkan kadar SOD tikus galur wistar (Rattus norvegicus) yang diberi aktivitas fisik. Disarankan agar dilakukan penelitian lebih lanjut tentang bentuk/sediaan lain ekstrak daun pepaya (Carica Papaya L) yang lebih bermanfaat, aman dipergunakan dan lebih mudah diproduksi secara besarbesaran, khususnya di Sumatera Utara atau daerah lain yang juga banyak ditumbuhi pohon pepaya (Carica Papaya L).
Factors influencing balanced diet in patients with type 2 diabetes mellitus based on theory of planned behavior Fentia, Lia; Ginting, Chrismis Novalinda; Chiuman, Linda
Malahayati International Journal of Nursing and Health Science Vol. 8 No. 2 (2025): Volume 8 Number 2
Publisher : Program Studi Ilmu Keperawatan-fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/minh.v8i2.617

Abstract

Background: Type 2 diabetes mellitus (DM) is a chronic disease that continues to increase globally, with a significant health and economic burden. A balanced diet is a key component of type 2 DM management. Purpose: To analyze the factors that influence balanced diet behavior in patients with type 2 DM in Pekanbaru using the Theory of Planned Behavior (TPB) approach. Method: This study used a quantitative method with a cross-sectional design. Data were collected from 117 patients with type 2 diabetes who were registered at the Pekanbaru Health Center. The variables studied included knowledge, attitude, family support, and the role of health workers in balanced diet behavior. Data analysis was performed using chi-square and Odds Ratio (OR) tests to determine the relationship and the chance of influence of independent variables on the dependent variable. Results: The results showed that low knowledge (OR=4.9), negative attitude (OR=2.5), lack of family support (OR=2.8), and non-optimal role of health workers (OR=3.2) had a significant influence on balanced diet behavior in patients with type 2 diabetes (p<0.05). Conclusion: Factors such as knowledge, attitude, family support, and the role of health workers significantly influence the balanced diet behavior of patients with type 2 diabetes. Suggestion: Education-based interventions and strengthening social support are needed to improve patient adherence to a balanced diet.
Peripheral Blood Smear Eosinophil Differential Count Comparison in Patients with Skabies and After One Week Recovered from Scabies Patriyuni, Tri; Nasution, Sri Wahyuni; Chiuman, Linda
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Vol.9 No.2 November 2023
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v9i2.12416

Abstract

Scabies is a skin infection disease caused by infestation and sensitization of the mite Sarcoptes scabiei, easily transmitted from person to person. Immune response has a crucial role in secondary complications and morbidity of individuals with scabies. Eosinophil is essential in defense against parasites but also contribute to tissue dysfunction and damage in allergic diseases. The purpose of this study was to compare the peripheral blood eosinophils differential count of patients while suffering from scabies and one week after recovered from scabies. This is an analytic comparative study with a cohort design. Sample size of 30 subjects calculated with sample size formula for paired categorical-numeric analytic research. Wilcoxon test was performed  for data analysis due to the data not normally distributed. The result of this study showed the mean peripheral blood differential eosinophil count of patients while suffering from scabies was 3,6% (3% - 5%) whereas one week after recovered from scabies was 2,37% (2% - 3%). There was signicant difference in the peripheral blood differential eosinophils count between patients while suffering from scabies and one week after recovered from scabies with a p value <0.05.
Analysis of Nurse and Midwife Job Satisfaction on Training Programs, Provision of Welfare and Implementation of Position Promotion at Royal Prima Marelan Hospital Leony, Catherine; Ginting, Chirmis Novalinda; Chiuman, Linda
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Vol.9 No.2 November 2023
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v9i2.12510

Abstract

Feelings of satisfaction at work can have a positive impact on behavior, such as discipline, morale, and loyalty. Job satisfaction is the key to the productivity of an organization, especially health services. In fact, job satisfaction and well-being of health workers play an important role in the quality of health services. Nurse jobsatisfaction is related to nurse performance, service quality, and increased patient satisfaction. The purpose of this study was to analyze the job satisfaction of nurses and midwives with training programs, providing welfare and implementing promotions at RSU Royal Prima Marelan. The sample in this study were 76 nurses and midwives at RSU Royal Prima Marelan with the sampling technique using total sampling. The analysis used in this study was univariate, bivariate and multivariate analysis. The results of this study indicate that there is an effect of the training program on the job satisfaction of nurses and midwives at RSU Royal Prima Marelan. There is an effect of providing welfare on the job satisfaction of nurses and midwives at RSU Royal PrimaMarelan. There is an effect of implementing promotion on the job satisfaction of nurses and midwives at RSU Royal Prima Marelan. There is an influence of training programs, provision of welfare and implementation of promotion on the job satisfaction of nurses and midwives at RSU Royal Prima Marelan. The independent variable that has the most influence on the job satisfaction of nurses and midwives at RSU Royal Prima Marelan  is the variable providing welfare. There is an influence of the influence of training programs, providing welfare and implementing promotion on the job satisfaction of nurses and midwives at RSU Royal Prima Marelan. 
Determinants of Independence in Exclusive Breastfeeding among Mothers with Diabetes Mellitus: A Cross-Sectional Study from Indonesia Yulita, Emi; Ginting, Chrismis Novalinda; Chiuman, Linda; Erika, Erika
Journal of Current Health Sciences Vol. 5 No. 2: 2025
Publisher : Utan Kayu Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47679/jchs.2025121

Abstract

The global rise in diabetes mellitus (DM) among women of reproductive age poses significant challenges to achieving optimal exclusive breastfeeding (EBF) rates, especially in low- and middle-income countries such as Indonesia. This study aimed to examine the relationship between knowledge and experience of mothers with DM and their independence in providing EBF, addressing an urgent need for targeted intervention and policy support for this vulnerable population. An analytic observational study with a cross-sectional design was conducted at community health centers in Pekanbaru from June to November 2024, involving 98 breastfeeding mothers diagnosed with DM, recruited through convenience sampling. Structured questionnaires measured maternal knowledge, prior breastfeeding experience, and independence in EBF. The results showed that 57.1% of mothers had good knowledge and 53.1% had adequate breastfeeding experience, while 69.4% demonstrated independence in providing EBF. Bivariate analysis revealed significant relationships between knowledge and independence (p = 0.026) as well as experience and independence (p = 0.001). These findings underscore the importance of enhancing education and support for mothers with DM to improve EBF practices. It is recommended that healthcare policies and programs prioritize continuous, tailored education and counseling to empower mothers with DM and increase EBF coverage.
Co-Authors Adrian Adrian Adrian Adrian Afina, Lubna Agung Adha Witasa Dewana Akalili, Cory Cintia Alexander Simanjuntak Alexander, Rico AMALIA, TIARA Amir, Widya Pasca Andika Zayani Tambunan Anditha, Arie Tika Anggraeni, Wenti Arif, Maria Nisaul Aulia, Rumi Azah, Yunita Wannur Bagas Dwi Sanjaya Bangun, Chrismas Gideon Bangun, Primta Binarwan Halim Br Ginting, Lois Eprillia Bukit, Christin Debora Chairun, Ryeo Ramadhan Chintya Darma, Gladys Chiuman, Veranyca Claudia Tanamal Colin, Vito Coray Carolyn Ruth Pardede, Eifel Datitha Alodia Br Kaban, Karina DEWI SARTIKA Dhillon, Neha Amar Dika Suranda Dwi Puspitasari Dzil Fikri Edy Fachrial Erika Erika Ermi Girsang Fahlevy, Ridho Fazwiansyah Darlin Muniro Febriani Simanjuntak, Lorena Felix, Jesslyn Fentia, Lia Ferdinand, Sahna Fiska Maya Wardhani gan, claris cyntha deninta Ginting, Chirmis Novalinda Ginting, Chrismis Novalina Ginting, Chrismis Novalinda Ginting, Sahna Ferdinand Girsang, Ermi Gozali, Juliana Grandis, Lexandria Gusbakti Gusbakti Rusip hafizha, Shalli Haicha Pritama, Irza Halim, Angel Jonathane Halim, Michael Handayani, Rr. Anisa Siwianti hardiansyah siregar Harmileni Hasya, Muhammad Nawal Hestina Hidayatti, Mustika Ibnu, Syahroni Iksen, Iksen Indriani, Vidya Intan Hasibuan, Febria Nurul Ira Syaputri Irwan Irwan irza Haicha Pratama Iskandar, Ari Rahman Janice Janice Kosasih, Michaela Kotsasi, Fransisca Krishna, Priyanka Kurniawan, Gracella Verren Lawrence, Christopher Leony, Catherine Levinna, Levinna Lie, Veronica Liena, Liena lister , Clarissa Lister, Gilbert Lumbantobing, Christina J. R. Esmaralda Lumbantobing, Christina J.R Esmaralda Lumbantobing, Christina J.R.E. Marfitania, Taranipa Maswarni Mawarni, Evi Michael Michael MICHELLE HENDRIANI DJUANG Miranda Winda Sari Sitorus Mukti, Ade Indra Nadapdap, Thomson Nasution, Ali Napiah Nasution, Atika Rimalda Nasution, Isna Gita Amalia Novalinda, Chrismis Nurlaela, Lia Olivia Laurent Ong, Gabriella Fransisca Ongko, Nicolas Xavier Pardianto, Gede Pasaribu, Jelita Pebriani Patriyuni, Tri Permata Khaira, Azzuhra Pinem, Sabriela Br Puspita, Sunny Putri, Muna Soraya Rajagukguk, Samuel Joshua Hamonangan Tua Rambe, Natasya Septiana Razoki, Razoki Rizki, Kartika Sari Sagala, Agasy Gideon Admiral Sahna Ferdinand Ginting Saragih, Chanli Saragih, Reyini Namora L. Sebayang, Dwi Putri Agita Sembiring, Mahral Effendi Sihombing, Bungaran Simarmata, Hans Pangestu Siti Hardianti, Siti Sitorus, Josua Panangian Soekardi, Adi Stanliko, Stanliko Stefenie Suandy, Suandy Suhartomi Sulistijanto, Eddy Suyono, Tan Syahputra, Hariyadi Dharmawan Sylvana, Dhini Tambunan, Ridhona Tan Suyono Tanamal, Claudia Tandiono, Michelle Tarigan, Elviyanti Tarigan, Setia Budi Tengku Rachmi Hidayani, Tengku Rachmi Tia Triyanti Tjendera, Mariaman Utami, Sherlinda Putri Utomo, Wilbert Waldo Varerina, Ria Br Perangin-angin Vera Estefania Kaban vera vera, vera VERONICA VERONICA Virgoh, Livia WAHYU WIDOWATI Wardhani, Fiska Maya Wijaya, Johanna Fransiska Wijaya, Linda Leonando Winda Sari Yosefa, Stephanie Renata Yuliansyah, Jeri Yulita, Emi Yusmaini, Yusmaini Zendrato, Ronauli Muliani