Tarigan, Amira Permatasari
Department Of Pulmonology And Respiratory Medicine, Faculty Of Medicine, Universitas Sumatera Utara/Universitas Sumatera Utara Hospital, Medan

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The Relationship of Blood Eosinophils Levels with Degree of Exacerbation in COPD Patient at Usu General Hospital Deneuve, Olivia Monica; Pradana, Andika; Tarigan, Amira P.
Journal of Society Medicine Vol. 3 No. 7 (2024): July
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i7.155

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Introduction: During acute exacerbations of chronic obstructive pulmonary disease (COPD), blood eosinophil count has the potential to predict treatment response. Nevertheless, there hasn't been enough research done to determine whether blood eosinophil numbers in a stable state can forecast an eosinophilic exacerbation. Methods: This study was a retrospective cohort analysis performed July-August 2022 to July-August 2023. Subject were 44 COPD patients who were treated at the outpatient clinic. Blood samples measured blood eosinophil levels. We determined an absolute cut-off point for blood eosinophil count at stable COPD in order to identify the rate of exacerbation. Results: Based on the Kruskal-Walli’s test, there was a significant relationship between blood eosinophils and the level of exacerbations in COPD patients (p value = 0.003). Conclusion: We established a relationship between the rate of exacerbation and blood eosinophil counts during stable COPD. The rate of exacerbation and eosinophil counts showed a strong positive relationship. Our findings should be confirmed by prospective and further research in different populations.
Survival Rate of Chronic Obstructive Pulmonary Disease Patients with Type II Respiratory Failure at Haji Adam Malik Hospital Nahrisyah, Putri; Syahrani, Fajrinur; Tarigan, Amira Permatasari; Ashar, Taufik
Journal of Society Medicine Vol. 3 No. 8 (2024): August
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i8.161

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Introduction: Chronic obstructive pulmonary disease is associated with acute exacerbations that can lead to respiratory failure and as major cause of morbidity and mortality worldwide. The Aim of study was to explore survival rate of COPD patients with type II respiratory failure Methods: Observational research with retrospective cohort design using data from medical records of chronic obstructive pulmonary disease patients with type II respiratory failure treated at H. Adam Malik General Hospital Medan for 10 months from November 2021 to September 2022. Analyzed of independent and dependent variables used Chi Square test. To obtain most dominant independent variable that influence dependent variable, a multiple logistic regression test is used. Results: There were 21 patients (50%) who alived until end of research but also 21 deaths occured. Survival rate was 50% with a median survival time 14 days (CI 95%: 7.178-20.822 days). Survival rate of COPD patients with type II respiratory failure who do not routinely received therapy was 16.7% with a median survival time 4 days (CI 95%: 42.962-5.039). Survival rate of COPD patients with type II respiratory failure who routinely received therapy was 75%. Based on log rank test, there was a significant difference median length of life between patients who did not and who routinely received therapy (p <0.001). Conclusion: The survival rate in COPD patients who regularly use inhaler therapy is significantly higher than patients who do not routinely use inhaler therapy.
The Association of Electric Cigarette Using Period with Respiratory Symptoms in Male E-Cigarette User Saragih, M. Khairul Aswin; Tarigan, Amira P.
Journal of Society Medicine Vol. 3 No. 8 (2024): August
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i8.163

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Introduction: The increasing trend of e-cigarettes user is often found in productive young people, especially those who are undergoing education. The use of electric cigarettes can cause respiratory complaints such as coughing, coughing up phlegm and shortness of breath. To identify the subject characteristic and to examine association between e-cigarette using period with respiratory symptoms in e-cigarrette male user who are undergoing education in Senior High School and Medical Education in Medan Methods: This study took samples of research subjects using two groups, where each group numbered 15 people, these groups were entered according to the inclusion and exclusion criteria, with the pearson correlation test using the ATSQ instrument to assess respiratory symptoms. Results: The age range of 21-25 years is the most users of e-cigarettes (43.4%), the most education is in the form of professional general practitioner education in this study (43.3%). Respiratory complaints that were often felt by subjects were coughing in the morning which occurred most often 1-2 times a week and shortness of breath during exercise which appeared less than once per week. The pearson test shows r count > r table (0.883 > 0.641) and is positive. Conclusion: There is an association between e-cigarette using period with respiratory symptoms, where the longer you use, the more severe the respiratory symptoms will be.
Anxiety Levels of Severe COVID-19 Patients at Haji Adam Malik Hospital Medan in 2022 Nurul Citta Banu Putri; Tarigan, Amira Permatasari; Pendiaman Pandia; Andika Pradana; Putri Chairani Eyanoer; Elmeida Effendy
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 2 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i2.11941

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Background: The COVID-19 pandemic is affecting the healthcare system and causing psychological changes, not only among healthcare professionals but also among citizens. These psychological changes are caused by depression, fear, anxiety, or insecurity. This study aims to investigate the anxiety level of severe COVID-19 patients who were treated at Haji Adam Malik General Hospital Medan in 2022 Method: This research is a descriptive observational study at the Department of Pulmonology and Respiratory Medicine Haji Adam Malik Hospital Medan from January 2022 until several samples were fulfilled. Sampling was done by consecutive sampling technique by filling Google Form questionnaire. The Hospital Anxiety and Depression Scale (HADS) questionnaire consists of seven items which can breakdown into anxiety subscales. The detail scores for every item ranged from zero to three. Score three indicated the highest level of anxiety. A total subscale score of >8 points out of 21 indicates significant anxiety symptoms. Data were analyzed descriptively to find out the frequency distribution of research subjects based on research sample characteristics. Results: From 36 research samples, 23 samples (63.9%) were male, and 13 samples (36.1%) were female. On anxiety levels, it was found that HADS-A scores were severe in  21 patients with severe COVID-19 (58.3%) and moderate levels in 15 patients (41.7%) with severe anxiety levels. Conclusion: Anxiety levels appear to be significantly increased in patients with severe COVID-19
Relationship between LDH Levels with COVID-19 Degree of Severity Tambunan, Adrian Nurrachman; Ganie, Ratna Akbari; Tarigan, Amira Permatasari
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 4 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i4.14414

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Background: LDH has proved to be a significant predictor for prognosis and follow-up in COVID-19 patients. Several studies report elevated LDH in hospitalized COVID-19 patients to be associated with a higher risk of death. Increased LDH levels can result from any tissue damage due to SARS-CoV-2 infection. The study aims to describe the relationship between LDH levels with COVID-19 19 degree of severity. Methods: This study is a cross-sectional study of 55 patients who confirmed positive by RT-PCR SARS-CoV-2 at H. Adam Malik General Hospital Medan (November 2021 – Maret 2022). Examination of the LDH level was carried out by the Chemiluminescent Immunoassays method (Abbott Architect). COVID-19 degree of severity was assessed based on the diagnostic criteria for COVID-19 cases in Indonesia. Results: Among the 55 COVID-19 patients in this study, the average age found was 45.73, with men 54.5%. Moderate, severe, and critical patients were found in 63.6%; 29.1%; and 7.3% respectively. The mean LDH level at admission was 278 U/L, higher in the severe (333.19 U/L) and critical (465.75 U/L) groups compared to the moderate (231.31 U/L) groups. Increased LDH ≥ 256 U/L proved to be related to COVID-19 degree of severity upon hospital admission (CI 95%; p = 0.001). Conclusions: LDH levels that increased ≥ 256 U/L were significantly related to COVID-19 degree of severity during hospital admission.
The Relationship between Malnutrition and Quality of Life in Stable Chronic Obstructive Pulmonary Disease Patients at Prof. Dr. Chairuddin P. Lubis Hospital Field Dalimunthe, Muhammad Bayhaqi; Pradana, Andika; Tarigan, Amira Permatasari; Amelia, Rina
Journal of Society Medicine Vol. 3 No. 9 (2024): September
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i9.164

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Introduction: Malnutrition is a serious problem in patients with COPD, it interferes with normal skeletal muscle function, with reduced muscle mass and decreased respiratory muscle strength and endurance. It also contributes to respiratory muscle dysfunction, disease severity, and disability progression. Malnutrition is associated with disease severity, associated with more severe exacerbations, and increases the length of hospital stay. Malnutrition in COPD is described with varying prevalence rates ranging from 30-60%. The aim of this study was to analyse the relationship between malnutrition and quality of life in patients with COPD. Method: The research design is an observational analytic conducted from November 2023 to March 2024. The study population was COPD patients who sought treatment at the Pulmonary Polyclinic at RSCPL with a total sample using the consecutive sampling method of 91 people. Manultrition assessment by measuring TB and BW of patients when they arrived and assessing quality of life with the SGRQ questionnaire, Data processing using SPSS by correlating malnutrition with quality of life, degree of shortness of breath, and spirometry. Results: There was a significant positive correlation between malnutrition and quality of life (p=0.001) with the degree of shortness of breath (p=0.014) and spirometry (p=0.001). Conclusion: We found an association between malnutrition and quality of life, degree of breathlessness and spirometry of patients with COPD, further prospective studies in other populations are needed to validate the results of this study.
The Effect of Providing Education on the Use of Inhalers on Asthma Degrees Based on the Asthma Control Test (ACT) in Patients at Tanjungpura Hospital Bayani, Sri; Tarigan, Amira Permatasari; Pandia, Pandiaman; Amelia, Rina; Jefri, Budi
Journal of Society Medicine Vol. 3 No. 10 (2024): Oktober
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i10.168

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Introduction: The main goal of asthma treatment is to control symptoms and reduce emergency department (ED) visits due to acute exacerbations. Drug delivery through inhalation is an important component of asthma management. Patients with asthma should have a good knowledge of their disease to recognize signs of worsening that can be prevented by early detection. Asthma control can be evaluated using the Asthma Control Test (ACT). To determine the effect of providing education on the use of inhalers on the degree of asthma based on the ACT in patients at Tanjungpura Regional General Hospital. Methods: This quasi-experimental study conducted from March 2024 to May 2024, used a one-group pre-test and post-test design to evaluate the effect of education via smartphone applications on asthma control (ACT). Obtained 54 patients who were diagnosed asthma at Tanjungpura Regional General Hospital. The sample consisted of asthma patients using inhalers, selected consecutively based on inclusion and exclusion criteria. Results: Most patients were female (64.8%) with ages 18-60 years (83.3%). The majority were housewives (46.2%). Post-test showed that 75.9% of patients had partial asthma control. All patients (100%) used inhalers correctly after education. There was a significant difference in ACT results before and after education (P-value 0.001) and an increase in ACT scores after the first and second education (P-value 0.002 and 0.001, respectively). Conclusion: Providing education on the use of inhalers has a positive effect on ACT scores in asthma patients, with an increase in the mean ACT score from 15.67 before education to 17.11 after the first education, and 20.96 after the second education.
A Study of Relationship Between Asthma Control Test, Lung Function, & Hospitalization Putra, M Yusuf Adira; Tarigan, Amira Permatasari; Pradana, Andika; Resti, Riska; Ramadhani, Adini Arifah; Nasution, Syafiah Amalina
Journal of Society Medicine Vol. 3 No. 12 (2024): December
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i12.179

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Introduction: The Asthma Control Test (ACT), developed in 2004, is a crucial tool for assessing asthma control. It facilitates discussions between patients and healthcare providers, guiding treatment decisions based on symptom severity. ACT evaluates symptoms over the past four weeks, while pulmonary function tests like forced expiratory volume in one second (FEV1) and peak expiratory flow (PEF) provide objective measures of airway function, offering complementary insights. Method: This cross-sectional study was conducted at Prof. Chairuddin Panusunan Lubis USU Hospital. Asthma patients were recruited, their characteristics documented through interviews, and spirometry was performed to assess lung function. Results: A significant proportion of patients had uncontrolled asthma based on ACT scores, which correlated with decreased lung function and higher risks of exacerbations. The study also explored characteristics of lung adenocarcinoma patients. Most were male (76.4%), heavy smokers (70.6%), and aged over 60 (52.9%). A majority (70.6%) were at Stage IVA, with pleural metastases being the most common. ALK mutations were detected in 5.8% of cases using immunohistochemistry. Conclusion: Achieving optimal asthma control remains a priority to reduce exacerbation risks and improve outcomes. ACT is a practical, patient-centered tool for identifying uncontrolled asthma and guiding management strategies. The adenocarcinoma findings highlight the need for early detection and targeted therapies in lung cancer care. These results reinforce the value of combining patient-reported outcomes and objective tests in disease management.
The Relationship Between ICS LABA Administration and Blood Eosinophil Levels in COPD Patient at USU General Hospital Deneuve, Olivia Monica; Pradana, Andika; Tarigan, Amira P
Journal of Society Medicine Vol. 3 No. 12 (2024): December
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i12.180

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Introduction: Blood eosinophil count may predict treatment response in patients  with chronic obstructive pulmonary disease (COPD) during acute exacerbations. However,  the ability of blood eosinophil counts in stable status to predict eosinophilic. Method: This was a cohort retrospective study performed Juni-August 2022 to Juni-August 2023. Subject were COPD patients who were treated at the outpatient using ICS LABA therapy. Blood samples measured blood eosinophil levels first and control. Results: Based on Wilcoxon test test, there was a significant positive positive correlation of eosinophil counts between ICS LABA  Administration and Blood Eosinophil Levels in COPD Patient at USU General Hospital. Conclusion: We demonstrated association between ICS LABA Administration and Blood  Eosinophil Levels in COPD Patient (p value = 0.02).
Analysis of Determinant Factors Affecting the Behavior of Intensive Care Nurses about Ventilator-Associated Pneumonia (VAP) Bundle Care Nani Andriani; Nurhidayah, Rika Endah; Amira Permatasari Tarigan
Caring: Indonesian Journal of Nursing Science Vol. 6 No. 2 (2024): Caring: Indonesian Journal of Nursing Science
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijns.v6i2.18050

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Ventilator-associated pneumonia (VAP) commonly arises due to the use of invasive endotracheal tubes, which facilitate the entry of bacteria into the respiratory system. VAP typically develops after a patient has been on mechanical ventilation for more than 48 hours. This study aims to analyze the determinant factors influencing the behavior of intensive care unit (ICU) nurses regarding VAP management at a General Hospital in Medan, Indonesia. The study employed a quantitative research approach with a survey design, involving 56 ICU nurses. The results of the multivariate analysis indicated significant p-values for the variables of education (p = 0.014), length of work experience (p = 0.004), and training (p = 0.013), demonstrating their collective influence on ICU nurses’ behaviors toward implementing VAP bundle care. Among these factors, the availability of facilities emerged as the most significant determinant, with the highest odds ratio (OR = 3.486). Nurses who had received training were 3.486 times more likely to exhibit appropriate behavior when providing VAP bundle care interventions compared to those who had not undergone such training. Based on these findings, it is recommended that every ICU nurse enhance their skills and knowledge through comprehensive training programs on VAP bundle care.
Co-Authors Afiatika Ahsani Afniwati Agus Dwi Susanto Andika Pradana Andika Pradana Andika Pradana Andika Pradana Andriani, Rizki Apriani, Fitri Ardinata, Dedi - Armi Mawaddah Aznan Lelo Bayani, Sri Caecilia Marliana Chandra F Zendrato Christine, Tamara Dalimunthe, Muhammad Bayhaqi Damayanti, Siti Darmawan, Nengah Deneuve, Olivia Monica Dewi Elizadiani Suza ELMAN BOY Elmeida Effendy Endang Susilawati Endang Susilawati Endy Todo Sirait Erna Mutiara Erna, Mutiara Evi Karota Fajrinur Syarani Febrina Susanti Firdaus, Ruby Fotarisman Zaluchu, Fotarisman Ghamal Arif Hanafiah Girsang, Isah Masdiana Harahap, Juliandi Helyanna Helyanna Hisham Farouk Hutabarat, Eva Susanti Debora Jefri, Budi Jubilette Windy Hutabarat Juliandi Juliandi Kawati, Salma Merda Listyoko, Aditya Sri Lucia Aktalina M. Sinaga, Bintang Yinke Marini Puspita Sari Martina Evelyn R.H Maryaningsih, Maryaningsih Miranda, Melly Monica, Nanda Soraya Muhammad Amin Nahrisyah, Putri Nainggolan, Nuryunita Nani Andriani Nasution, Nurromsyah Nasution, Syafiah Amalina Noni Novisari Soeroso Nurul Citta Banu Putri Nuryunita Nainggolan Orita Satria Ozar Sanuddin Pandia, Pandiaman Pandiaman Pandia Pandiaman Pandia Pandiaman, Pandia Pendiaman Pandia Pinem, Agung Haganta Pohan, Indah Triana Sari Putra, M Yusuf Adira Putri C Eyanoer Putri Chairani Eyanoer, Putri Chairani Putri Eyanoer Raffael, Frans Rahmah, Lestari Ramadhani, Adini Arifah Ratna Akbari Ganie, Ratna Akbari Resti, Riska Rhinsilva, Ella Rianti Tarigan Rifda Hayati Rika Endah Nurhidayah Rina Amelia Rocky Malindo Sidabutar S*, Erfiyani Salma Merda Kawati Samoedro, Erlang Santi Syafril, Santi Saragih, M. Khairul Aswin Sembiring, Rosita Juwita Septiani Waruwu Shilvanna Litania Sihombing, Benny Simanjuntak, Donal Anjar Sinaga, Sudirman Parningotan Sri Sumartiningsih Susanthy Djajalaksana Syahrani, Fajrinur Syarani, Fajrinur Tambunan, Adrian Nurrachman Tari Mediyanti Tarigan, Setia Putra Taufik Ashar Tri Setia Negara Sinulingga Ulfa hasanah Vera, Yeni Vinda Sari Ermiza Nasution Wahyuni, Arlinda Sari Wilson Arthur Zein Wina Elizabeth Octaria Saragih Wiwien Heru Wiyono Yahwardiah Siregar Yessi Andriani Zainal Yetty Machrina Yusni Yusni Zulkarnain Zulkarnain Zulkarnain Zulkarnain