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Uji Efektivitas Antibakteri Ekstrak dan Fraksi Bunga Telang (Clitoria Ternatea L.) terhadap Pertumbuhan Staphylococcus Aureus ATCC 25923: Penelitian Tantri Dwi Lestari; Tatiana Siska Wardani; Vivin Marwiyati Rohmana
Jurnal Pengabdian Masyarakat dan Riset Pendidikan Vol. 3 No. 3 (2025): Jurnal Pengabdian Masyarakat dan Riset Pendidikan Volume 3 Nomor 3 (Januari 202
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jerkin.v3i3.389

Abstract

Acne is a skin disease where the oil glands are blocked by dirt that can be infected by bacteria. One way to cure acne is by using compounds that have antibacterial effects. Butterfly pea flowers contain compounds that are believed to inhibit bacterial growth at a certain percentage. The purpose of this study was to determine the antibacterial effectiveness of butterfly pea flower extracts and fractions in certain concentrations. This type of research uses experimental. This study was divided into 6 groups with 4 different concentrations, namely positive control (Gentamicin), negative control (DMSO 10%), Butterfly pea flower extract (15%, 20%, 30%, 40%), Aquadest Fraction (15%, 20%, 30%, 40%), N-hexane Fraction (15%, 20%, 30%, 40%), and Ethyl acetate fraction (15%, 20%, 30%, 40%). The results of the bacterial inhibition zone data were analyzed using SPSS 26 with a confidence level of 95%. The results of this study indicate that the extract and fraction of butterfly pea flowers provide antibacterial effects on the growth of staphylococcus aureus bacteria at concentrations of 15%, 20%, 30%, and 40%. The best inhibition zone is in the ethanol extract of butterfly pea flowers with an average inhibition zone of 9.3 mm at a concentration of 40%.
Training On The Making Of Solid Soap By Utilizing Used Cooking Oil Waste By Pembinaan Kesejahteraan Keluarga (PKK) Women In Wangen Village Tatiana Siska Wardani; Erna Chotidjah Suhatmi
VSJ | Veteran Society : Jurnal Pengabdian Masyarakat Vol. 1 No. 2 (2020): Veteran Society : Jurnal Pengabdian Masyarakat
Publisher : Fakultas Hukum, UPN Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/vsj.v1i2.11

Abstract

Social welfare can be improved in various ways that can be done, for example, through community empowerment programs. The part of the community that can be empowered are housewives who are members of the PKK organization, especially in Wangen Village, Polanharjo District, Klaten Regency. The impact of environmental pollution is due to the disposal of used cooking oil and is followed by an increase in the use of cooking oil due to the appeal to stay at home during the Covid-19 pandemic. The existence of this makes a training program and assistance for the utilization of cooking oil waste into soap is the right thing to deal with this problem. The specific goals and targets to be achieved in this activity are that PKK mothers are interested and motivated to become entrepreneurs, to form groups of PKK members who become economically independent by producing soap. In order to achieve this goal, a community service program was carried out by a lecturer at the University of Duta Bangsa Surakarta who provided soap production training conducted by PKK women in Wangen Village. The result of this service is an increase in the skills of PKK Village women in Wangen in making soap from used cooking oil waste.
Uji Aktivitas Antibakteri Ekstrak dan Fraksi n-Heksan, Etil Asetat, Air Kulit Buah Naga Putih (Hylocereus Undatus) Terhadap Staphylococcus Epidermidis ATCC 12238 Muhammad Abdul Azis; Tatiana Siska Wardani; Anna Fitriawati
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 4 (2024): Juli : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i4.478

Abstract

Research on the antibacterial test of dragon fruit peel extract carried out by Anggraini & Harris (2017) shows that white dragon fruit extract is able to inhibit the growth of epidermal Staphylococcus bacteria with the lowest concentration, namely 25%, producing an average diameter of the inhibition zone of 13.7 mm, while for the highest concentration, namely 100%, it produces an average diameter of the inhibition zone of 17.7 mm. To determine the more effective antibacterial effect of white dragon fruit peel extract, the research continued to the fractionation stage to separate compounds based on polarity level. The solvents used are water which is a polar solvent, ethyl acetate which is a semi-polar solvent, and n-hexane which is a nonpolar solvent (Yohanes, 2020). Based on the description above, researchers are interested in conducting research on testing the antibacterial activity of ethanol extract and n-hexane fraction of white dragon fruit peel (Hylocereus undatus) against Staphylococcus epidermidis bacteria.
Uji Aktivitas Antibakteri Ekstrak, Fraksi Air, Fraksi Etil Asetat, Fraksi n-Heksan Daun Petai Cina (Leucaena leucocephala) Terhadap Bakteri Staphylococcus aureus ATCC 25923 Muhammad Andira Ibnu Shina; Tatiana Siska Wardani; Kusumaningtyas Siwi Artini
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 6 (2024): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i6.785

Abstract

Shina, mai., 2024, test of antibacterial activity of extract, water fraction, ethyl acetate fraction, and n-hexane fraction of chinese petai leaf (leuncaena leucocephala) against staphylococcus aureus atcc 25923, thesis, faculty of health sciences, duta bangsa university, surakarta one of the traditional medicines that currently has the potential to be developed is the chinese petai plant (leucaena leucocephala). Chinese petai leaves are used by the people of indonesia as a remedy for new and swollen wounds. Staphylococcus aureus is a gram-positive coccus bacterium that is the main pathogen in humans. Almost everyone has experienced a wide variety of staphylococcus aureus infections during their lifetime, from severe food poisoning to minor skin infections. The methods used in this study are diffusion and dilution. The purpose of this study was to determine the antibacterial activity of water extracts and fractions, ethyl acetate fractions, and n-hexane fractions of chinese petai leaves (leuncaena leucocephala), to find the most active extracts and fractions based on their inhibitory zones, and to determine the khm and kbm of the most active extracts against staphylococcus aureus atcc 25923. Based on research conducted on ethanol extract, water fraction, ethyl acetate fraction, and n-hexane fraction of chinese petai leaves have antibacterial activity against staphylococcus aureus atcc 25923. The most active extract in inhibiting staphylococcus aures atcc 25923 judging from its inhibition zone value is ethanol extract. Ethanol extract of chinese petai leaves has the same khm and kbm values, namely at a concentration of 25%.
Formulasi dan Uji Aktivitas Antibakteri Sabun Cair Ekstrak Daun Jeruk Purut (Citus hystrix) terhadap Bakteri Staphylococcus aureus ATCC 25923 dan Escherichia coli ATCC 25922 Iqbal Sirajudin Maulidinawan; Tatiana Siska Wardani; Bagas Ardiyantoro
JURNAL RISET RUMPUN ILMU KESEHATAN Vol. 4 No. 3 (2025): Desember : Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v4i3.6647

Abstract

Skin that is prone to bacterial infections requires proper care using products containing antibacterial agents. One potential alternative is kaffir lime leaves (Citrus hystrix), which are known to contain antibacterial compounds. This study aimed to evaluate the formulation of liquid soap containing kaffir lime leaf extract and to determine the optimal concentration for inhibiting bacterial growth. An experimental laboratory design was applied, and the antibacterial effectiveness was tested using the disk diffusion method against two test bacteria, namely Staphylococcus aureus and Escherichia coli. Statistical analysis was performed using One-Way ANOVA, followed by Scheffe’s post-hoc test to identify significant differences among treatment groups. The results indicated that the liquid soap containing kaffir lime leaf extract exhibited good physical quality and met standard parameters, including organoleptic evaluation, pH, viscosity, and foam height tests. Antibacterial testing showed that the highest inhibition zone against Staphylococcus aureus was observed at a 15% concentration with a zone diameter of 18.28 mm (strong category), while the highest inhibition zone against Escherichia coli was also at a 15% concentration with a diameter of 19.03 mm (strong category). The One-Way ANOVA results showed a significance value (p < 0.05), indicating a statistically significant difference among treatments for both bacterial species. These findings suggest that liquid soap formulated with kaffir lime leaf extract, particularly at a 15% concentration, has strong antibacterial activity and potential as an effective skin care product. Further studies are recommended to evaluate safety, stability, and long-term effectiveness.
FORMULASI DAN UJI EFEKTIVITAS ANTIBAKTERI SEDIAAN MOUTHWASH DARI EKSTRAK DAUN KEMANGI (Ocimum x africanum L.) TERHADAP BAKTERI Staphylococcus aureus Voen-Na, Cut Dara; Wardani, Tatiana Siska; Wicahyo, Septian Maulid
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 8 No. 2 (2025): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v8i2.1856

Abstract

The oral cavity is susceptible to bacterial infections because it has direct exposure to the outside environment, one of which is Staphylococcus aureus, which can cause oral health problems. The use of mouthwash as an additional treatment helps maintain optimal oral hygiene. Basil leaves (Ocimum x africanum L.) contain secondary metabolite compounds that have the potential to inhibit the growth of S. aureus. This study aims to determine the physical quality test of mouthwash of basil leaf extract and test its antibacterial effectiveness against S. aureus. This research method is laboratory experimental. Basil leaf simplicia powder (Ocimum x africanum L.) is macerated with 96% ethanol. Mouthwash formulations are made in concentrations of 4%, 6%, 8%, and 10%. Testing was carried out using the disc diffusion method to assess the antibacterial effectiveness against S. aureus ATCC 25923. Physical quality tests are also carried out on mouthwash preparations. The data from the antibacterial test results were analyzed using the One-Way ANOVA method. The results showed that the mouthwash preparation formula of basil leaf extract had good physical quality in terms of organoleptics, pH, specific gravity, viscosity, and clarity. The results of the statistical test showed a significant difference in the diameter of each group (P<0.05); mouthwash preparation at F4 (10%) had an inhibitory power against S. aureus bacteria of 8.46 mm with a bacterial inhibition zone of the medium category.
UJI AKTIVITAS ANTIBAKTERI SEDIAAN MASKER GEL EKSTRAK DAUN TAPAK DARA (Catharanthus roseus (L) G. Don) TERHADAP BAKTERI Staphylococcus aureus Agustina, Isnaini; Wardani, Tatiana Siska; Luthfiyanti, Niken
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 8 No. 2 (2025): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v8i2.1864

Abstract

Gel masks are semi-solid preparations that serve as skincare products with benefits, such as addressing various skin problems. This study aims to conduct a physical quality test on gel masks containing tapak dara leaf extract, determine the antibacterial activity of tapak dara leaf extract and evaluate the antibacterial activity of the tapak dara leaf extract gel mask against Staphylococcus aureus ATCC 25923 bacteria. This study uses both qualitative and quantitative analysis with experimental methods. The extraction of virgin leaves is carried out using the maceration method with a 70% ethanol solvent. The extracts and preparations are made into three concentrations: 10%, 20%, and 30%. The physical quality testing of tapak dara leaf gel masks includes organoleptic evaluation, homogeneity, pH, dispersion, and drying time. The results of one-way ANOVA for pH (sig. = 0.815), dispersion (sig. = 0.695), and drying time (sig. = 0.251) showed that the significance values were greater than 0.05. Tapak dara leaf extract demonstrates antibacterial activity against Staphylococcus aureus bacteria, with inhibitory zone diameters of 3.5 mm, 7.87 mm, and 9.85 mm. The gel mask preparation of virgin palm leaf extract exhibits antibacterial activity against Staphylococcus aureus bacteria, with inhibition zone diameters of 3.67 mm, 4.77 mm, and 7.4 mm. The results of one-way ANOVA on the activity of virgin palm leaf extract against Staphylococcus aureus bacteria showed a significance value less than 0.05.
UJI MUTU FISIK SEDIAAN LIP BALM DAN KADAR TOTAL ANTOSIANIN EKSTRAK DAUN JATI (Tectonagrandislinn., F.) Lindra Putri, Jessika Ukurmehuli; Hidayat, Rahmat; Wardani, Tatiana Siska
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 8 No. 2 (2025): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v8i2.1866

Abstract

Lip balm is a product that serves to prevent dryness of the lips by increasing moisture and protecting them from the adverse effects of the environment. In making this lip balm, Teak leaves (Tectonagrandislinn., F) are used as a natural colorant because they contain pigments, especially anthocyanins. Anthocyanins are flavonoid compounds that have antioxidant properties. This study aims to determine the total anthocyanin content in teak leaf extract and design a lip balm formulation that meets physical quality standards. In addition, the study also tested variations in concentration to find the best formulation. The type of research used with experimental methods involving physical quality tests of lip balm preparations and total anthocyanin levels of teak leaf extract.The results showed that lip balms with formula 0 (no extract), formula I (2% extract), formula II (3% extract), and formula III (4% extract) met the physical quality standards based on SNI 1-4399-1996, including in the aspects of homogeneity, adhesion, spreadability, viscosity, and pH. The total anthocyanin content in teak leaf extract was 68.298 mg/L. In addition, variations in extract concentration also affected the panelists' level of liking, where formula III with a concentration of 4% was the most preferred because it had an even composition, suitable pH, good spreadability and adhesiveness, and did not cause irritation.
FORMULASI DAN UJI EVALUASI SEDIAAN LIP BALM KOMBINASI EKSTRAK ETANOL DAGING LIDAH BUAYA (Aloe vera) DAN DAGING BUAH ALPUKAT (Persea americana Mill) SEBAGAI PELEMBAB BIBIR Masruroh, Sururul Kamalin; Wardani, Tatiana Siska; Listyani, Tiara Ajeng
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 9 No. 1 (2025): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v9i1.1980

Abstract

The lips are sensitive and prone to dryness and chapping, requiring special care. This study aimed to develop a Lip Balm preparation that meets physical quality standards and to determine its activity as a lip moisturizer. It also determined the optimal concentration for a Lip Balm formulation using a combination of 70% ethanol extract of Aloe vera and avocado (Persea americana Mill.) pulp. Aloe vera contains lignin, and avocado contains vitamins A, C, and E, which are essential for skin health. This study was conducted experimentally using five formula variations: F0 (0%), F1 (10%), F2 (15%), F3 (20%), and a positive control (Vaseline Repairing Jelly). Physical quality evaluation included organoleptic testing, homogeneity, pH, spreadability, adhesion, spreadability, moisture testing, irritation testing, hedonic testing, and stability testing. The results showed that all formulas had a semi-solid texture and color, varying depending on the extract concentration, were homogeneous, had a pH within the safe range (4.5-6.5), and met physical quality requirements. Moisture testing showed an increase in lip moisture levels after 14 days of use, with formula F3 providing the best moisturizing effect. In conclusion, the combination of Aloe vera and avocado (Persea americana Mill) extracts can be formulated into an effective Lip Balm as a natural lip moisturizer, with the best concentration in formula F3, with a moisture value of 47.3%.
MENGGALI DIMENSI ETIKA DALAM PELAYANAN FARMASI: SEBUAH TINJAUAN KOMPREHENSIF Chahyaningrum, Dhiyan; Fitriana, Lydia; Santoso, Aris Priyo Agus; Wardani, Tatiana Siska
Jurnal Ilmiah Global Farmasi (JIGF) Vol. 3 No. 3 (2025): JIGF - September
Publisher : PC IAI Sragen

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pelayanan farmasi penting untuk memberikan obat dan layanan berkualitas kepada pasien. Apoteker dan tenaga farmasi menghadapi berbagai situasi yang melibatkan pertimbangan etika. Tujuan penelitian ini adalah menganalisis dimensi etika terkait dengan pelayanan farmasi. Data dikumpulkan dari berbagai sumber, termasuk jurnal, buku, dan pedoman etika. Studi kasus dan contoh nyata dianalisis untuk menggambarkan situasi etis yang umum dihadapi oleh apoteker dan tenaga farmasi. Kode etik dan pedoman praktik yang dikeluarkan oleh organisasi profesi farmasi juga ditinjau. Hasil tinjauan ini mengungkapkan prinsip-prinsip etika yang relevan dalam pelayanan farmasi, seperti otonomi, keadilan, dan non-malefikasi. Konflik kepentingan dan komunikasi efektif juga penting. Tantangan etis lainnya termasuk privasi pasien, distribusi obat yang adil, dan pengelolaan konflik moral. Pelayanan farmasi yang etis adalah dasar penting dalam perawatan kesehatan. Memahami dan menerapkan prinsip-prinsip etika dalam praktik sehari-hari penting untuk pelayanan yang bermartabat. Penelitian dan pendidikan etika farmasi yang berkelanjutan dapat meningkatkan kesadaran dan kompetensi etika para profesional farmasi.   Kata kunci: etika; konflik kepentingan; pelayanan farmasi; prinsip etika; tenaga farmasi
Co-Authors ACHMAD FAUZI Adhe Wibawa Mahardika Putra Agung Widiastuti Agustina, Isnaini Akbar, Finica Dwi Al Fajri Razid Faizur Muhammad Alfi Risna Fadilla Aminnulloh, Muhammad Anita Dwi S Anita Dwi Septiarini Anita Dwi Septiarini Anita Dwi Septiarini Anna Fitriawati Annisa Kusuma Wardhani Ariyanti Ariyanti Artini, Kusumaningtyas Siwi Bagas Ardiantoro Bagas Ardiyantoro Baiq Mitasari Cahyono, Imam Sahid Chahyaningrum, Dhiyan Danang Raharjo Desy Ayu Irma Permatasari Devi Nur Indah Sari dewi mei ika widiyastuti Dian Pratiwi Dinar Aditama Nugroho Erikania, Susanti Erna Chotidjah Suhatmi Erna Chotidjah Suhatmi Faizah Ariqoh Fazlin Fauzi Febriyani, Rima Fitriana, Lydia Haikal Zanki hanif fathur rohman, muhammad Ikrima Rahmasari Iqbal Sirajudin Maulidinawan Istiara Subekti Kezia Putri Maha Dewi Kharisma Jayak P Khasanah, Isna Nur Khilda Hilyatul 'Ulya Khusain, Muhammad Fuad Zidane Kristanti Prihatin Sri Rejeki, Melinia Mega Kusumaningtyas Siwi A Kusumaningtyas Siwi Artini Kusumaningtyas Siwi Artini Lindra Putri, Jessika Ukurmehuli Listyani, Tiara Ajeng Luthfiyanti, Niken Mahadewi Putri Kezia Masruroh, Sururul Kamalin Muhammad Abdul Azis Muhammad Andira Ibnu Shina Muhhamad Aminulloh Muladi Putra Mahardika Nesya Sucitra Ni Luh Ari Yusasrini NOVISYIAHGIANT, DINA AMALIA Phiapresia, Safara Zulfa Pratama, Kharisma Jayak Purwaningsih Purwaningsih Raden Rara Anteng Pujowati Rahadyana, Riskaldila Zahra Rahmat Hidayat Rahmatillah, Annie rani, fahrenza meta Ratna Sari Dewi Ria, Septiyana Rita Anita Tanikolan Riztiandi Ardiansyah Rohmana, Vivin Marwiyati Sahadatun, Angga Aulia Saifana, Cindy Septia Santoso, Aris Priyo Agus Septian Maulid Wicahyo Septiyana Ria Siti Nur Hikmah Siwi, Melati Daru Suhatmi, Erna Chotidjah Tantri Dwi Lestari Toyang, Gresilia tri Mastuti, eni Triya Choirin Nisa Urip, Sri Khanti Utomo Kartika Endrat Verentika, Jumini Voen-Na, Cut Dara Wahyu Budi Utomo Wali Jati, Ilham Weri veranita Wimpy, W Yusuf, Dea Sagitarina