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Journal : Medula

Psoriasis Pustulosa Generalisata: Tinjauan Kasus Pada Geriatri Febe Sintia Kristiani; Dwi Indria Anggraini
Medula Vol 9 No 4 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i4.236

Abstract

Psoriasis is a chronic disease of the skin that is characterized by accelerated epidermal exchange and a faster keratinization process. Psoriasis has a variety of manifestations, one of which is generalized pustular psoriasis characterized as pustular sterile eruption. This case report aims to determine the diagnosis and management of generalized pustular psoriasis. Case, a 75-year-old woman complained of the emergence of pustule throughout the body since four days ago accompanied by burning and itching sensation. Some pustule confluence make a lake form (lake of pus), and some lesion consist of erythematous plaque with yellowish greasy scale. The patient has a history of hypertension, use of pain killer, and sudden stopping steroids. Based on history taking, physical examination and laboratory, the diagnosis of generalized pustular psoriasis is made. The treatment given was in the form of corticosteroid methylprednisolone intravenous injection 31,25 mg/ 12 hours, ranitidine intravenous injection 50 mg/12 hours, cetirizine peroral 1x10 mg, betametason valerate cream 0.1% in urea 10% cream.
Diagnosis dan Tatalaksana Psoriasis Muhammad Rafi Eka Putra; Dwi Indria Anggraini; Syahrul Hamidi Nasution; Hendra Tarigan Sibero
Medula Vol 13 No 2 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i2.656

Abstract

Psoriasis is a chronic skin inflammation characterized by clear erythematous plaques, rough scales, and layered silvery white plaques, especially on the elbows, knees, scalp, back, umbilicus, and lumbar region. 125 million people worldwide have psoriasis, with prevalence varying in different countries. Psoriasis has a prevalence of 1% to 3% in Europe and the United States. Psoriasis is a disease caused by an autoimmune condition. The diagnosis of psoriasis can be made based on the clinical picture. The physical examination should include examination of the primary lesion and other common areas affected by psoriasis including the scalp. A family history should be asked to support the diagnosis. The diagnosis can also be established by the presence of candle drip phenomenon, auspitz and kobner (isomorphic) which are symptoms of psoriasis. In addition, a histopathological examination can also be performed with a picture of hyperkeratosis, parakeratosis, acanthosis, Munro's abscess, papillomatosis and vasodilatation subepidermis. Psoriasis therapy is given topically in mild degrees and systemic therapy and phototherapy are given in moderate to severe psoriasis. Topical therapy that can be given is corticosteroids, vitamin D analogues, retinoids, TAR (LCD 3-10%), keratolytics (salicylic acid), and emollients. Systemic therapy used in moderate to severe cases includes acitretin, methotrexate, cyclosporin. Commonly used autotherapy in the treatment of psoriasis are narrowband ultraviolet B (NB-UVB), broadband ultraviolet B (BB-UVB), and topical 8-methoxypsoralen and UVA (PUVA).
Faktor-Faktor yang Mempengaruhi Derajat Kecacatan Kusta Fauziani, Andra Nabila; Anggraini, Dwi Indria; Hanriko, Rizki; Sibero, Hendra Tarigan
Medula Vol 14 No 1 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i1.936

Abstract

Morbus Hansen, also known as leprosy, is an infectious disease that is chronic or chronic. This disease is caused by the acid-fast bacillus (BTA) Mycobacterium leprae which is obligate intracellular. This disease can attack various body systems, including the peripheral nervous system, skin, mucosa, upper respiratory tract, reticuloendothelial system, eyes, muscles and bones. Based on WHO data for 2021, globally there were 133,781 cases of leprosy, with Indonesia ranking third highest in the world with 10,976 new cases after India and Brazil. Leprosy that is not treated properly can cause disability. There are two types of disability in leprosy, namely primary and secondary disability. Primary disability is caused directly by the Mycobacterium leprae bacteria, while secondary disability is a disorder that arises because the primary disability is not treated properly. The level of disability in leprosy is classified based on symptoms of damage to the eyes, hands and feet with levels 0, 1 and 2. Factors that influence the degree of disability in leprosy are grouped into demographic factors, internal factors and external factors. Demographic factors include age, gender, socio-economic status, occupation, and education level. Internal factors include the type of leprosy, length of suffering, number of nerves affected, and leprosy reaction. External factors include compliance with taking medication, delays in treatment, and self-care.
Faktor-faktor yang Mempengaruhi Keberhasilan Terapi Pasien Kusta Sagia, Nabilla Alsa; Anggraini, Dwi Indria; Wulan, Anggraeni Janar; Sibero, Hendra Tarigan
Medula Vol 14 No 2 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i2.937

Abstract

Leprosy is a chronic granulomatous infectious disease caused by the obligate intracellular bacterium Mycobacterium leprae (M. leprae). This disease comes from the Latin word "lepros" which means scale. M. Leprae bacteria enter the human body through 2 main routes, namely through the skin and the upper respiratory tract. Leprosy bacilli enter the human body through direct contact with the skin or nasal mucosa originating from droplets. Bacteria from droplets will survive for 2 days in a dry environment, even up to 10 days in a humid environment and low temperatures. The success of therapy for Morbus Hansen patients is expressed by RFT (Release from Treatment). RFT can be stated after the dose is fulfilled without having to undergo laboratory examination. PB (paucibacillary) patients who have received 6 doses (blister) of treatment within 6-9 months are declared RFT, without having to undergo a laboratory examination. MB (multibacillary) patients who have received 12 doses (blister) of MDT treatment within 12-18 months are declared RFT, without having to undergo a laboratory examination. The factors that play a role in the success of therapy for leprosy patients are age, gender, education, employment, knowledge, compliance with taking medication, and family support.
Anatomi dan Fisiologi Ginjal: Tinjauan Pustaka Alwiyah, Fadilah; Rudiyanto, Waluyo; Anggraini, Dwi Indria; Windarti, Indri
Medula Vol 14 No 2 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i2.977

Abstract

The kidneys are retroperitoneal organs located at the top on both sides of the III lumbar vertebra and attached directly to the abdominal or ventral wall of the M. psoas major and M. quadratus lumborum. The kidneys function to regulate the amount and concentration of ECF electrolytes and maintain nerve and muscle excitability, activating vitamin D which is important for calcium absorption in the digestive tract and producing erythropoietin which is a hormone to stimulate the bone marrow to form red blood cells. The main function of the kidneys is to filter and excrete metabolic waste products in the urine so that administration of toxic compounds or irritating compounds can cause degenerative changes such as fatty degeneration to necrosis of the kidneys. Disorders of the kidneys can disrupt kidney function. Chronic Kidney Disease (CKD) sufferers have several complications such as overhydration, hyperkalemia, metabolic acidosis, mineral and bone disorders, hypertension, anemia and dyslipidemia. The most common etiologies of CKD in adult patients are diabetes mellitus and hypertension. In children, the most common primary cause of PGTA is congenital abnormalities of the kidneys and urinary tract (such as obstructive uropathy, vesicoureteral reflux, renal dysplasia). Indonesian Nephrology Association (PERNEFRI) in 2006, which found that the prevalence of Chronic Kidney Disease (CKD) was 12.5%. Meanwhile, data according to the 2019 Health Insurance Administration (BPJS) shows that there were 1.93 million cases of kidney failure and 1.79 million cases in 2020. With this data, the author is interested in discussing the kidneys in more depth.
Hubungan Usia, Jenis Kelamin, Dan Pekerjaan Dengan Kejadian Dermatofitosis di Rumah Sakit Umum Daerah Dr. H. Abdul Moeloek Provinsi Lampung Periode 2017- 2021 Graceciela, Yohana Eva; Anggraini, Dwi Indria; Himayani, Rani; Sibero, Hendra Tarigan
Medula Vol 14 No 6 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i6.1097

Abstract

Dermatophytosis is a dermatophyte fungal infection that attacks keratinized tissues. This disease can be caused by various internal and external factors. The internal risk factors causing dermatophytosis include age, gender, and occupation. In addition to that, this study aimed at determining the relationship between age, gender, and occupation toward dermatophytosis cases. This study used an analytical observational design with a cross-sectional approach. The sample in this study consisted of 114 patients with dermatophytosis sourced from the secondary data in the form of medical records. The research data were conducted by using total sampling technique in RSUD Dr. H. Abdul Moeloek Lampung Province. The recorded data included the patients’ age, gender, occupational, and diagnosis. Then, the data were analysed using chi-square test presented in tabular form. The results showed that the majority of dermatophytosis patients were adults, female, and employees who worked in government/private institutions. The results of the chi-square test showed a significant value for the age variable (p = 0.035) and the gender variable (p = 0.041), while for the work variable there was no significant relationship (p = 0.615). There is a significant relationship between age and gender with the dermatophytosis cases and there is no significant relationship between occupation and the dermatophytosis cases.
Co-Authors Agustyas Tjiptaningrum Agustyas Tjiptaningrum Ahmad Fauzi Ahmad Sirajudin Alfi Yasmina Alwiyah, Fadilah Amira Zhafira Analia Analia Anggraeni Janar Wulan, Anggraeni Janar Annisa Adietya Pratama Annisa Cahyani Ayu Wulandari AYU WULANDARI Betta Kurniawan, Betta Dhipayasa Adirinarso Dian Isti Angraini Efrida Warganegara Elina Rahma Elina Rahma Emantis Rosa Erna Kristin Ety Apriliana Fauzi Ahmad Muda Fauziani, Andra Nabila Febe Sintia Kristiani Fitria Saftarina Graceciela, Yohana Eva Guntur Sulistyo Hakim, Lukmanul Hanna Mutiara, Hanna Hasril Mulya Budiman Helmi Ismunandar Hendra Tarigan Sibero Hendra Tarigan Sibero Hendra Tarigan Subero Hery Dian Septama Indri Windarti Isti Angraini, Dian iwan Dwiprahasto Jarir At Thobari Jhons Fatriyadi Suwandi Justiani, Andinni Aurellia Karima, Nisa Karimah, Nisa Kartika, Juspeni Kurniawaty, Evi Lania, Siska M. Fauzan Abdillah Rasyid M. Fitra Wardhana M. Syafei Hamzah Mayasari, Diana Muhamad Addin Syakir Muhamad Addin Syakir Muhammad Rafi Eka Putra Muhammad Syafei Hamzah Muhammad Yusran Muhammad Yusran Muhammad, Meizano Ardhi Mukhlis Imanto, Mukhlis Nisa Karimah Novita Carolia Pairulsyah Pairulsyah Piesta Prima Beta Pairul Putra, I Wayan Ardana Rahmatika, Achisna Rahmayani, Fidha Rani Himayani Rasmi Zakiah Oktarlina Rizki Hanriko Robert Bestak Rodiani Rodiani Rodiani, Rodiani Roro Rukmi Windi Perdani, Roro Rukmi Rudiyanto, Waluyo Sagia, Nabilla Alsa Sari, Mahala Ramah Silitonga, Yona Arisena Magdalena Suharmanto Suharmanto Syahrul Hamidi Nasution Syazili Mustofa Tri Umiana Soleha Tri Umiana Soleha Umniya Umniya Yisran, Muhammad Yulisna Yulisna Yustisya Khoirunnisa Zetira, Zihan