Article Per Year (5 Year)
p-Index From 2021 - 2026
6.06
P-Index
This Author published in this journals
All Journal Berkala Kedokteran Jurnal Surya Medika Bunda Edu-Midwifery Journal (BEMJ) Indonesia Berdaya INTERNATIONAL JOURNAL OF EDUCATION, INFORMATION TECHNOLOGY, AND OTHERS Farmasis: Jurnal Sains Farmasi Dinamika Kesehatan: Jurnal Kebidanan dan Keperawatan Journal of Pharmaceutical Care and Sciences Indonesian Journal of Nursing and Health Sciences (IJNHS) SENTRI: Jurnal Riset Ilmiah Journal of Artificial Intelligence and Digital Business Innovative: Journal Of Social Science Research Health Research Journal of Indonesia Journal of Advances in Medicine and Pharmaceutical Sciences Indonesian Journal of Pharmacy and Natural Product Majalah Cendekia Mengabdi Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Jurnal Farmasi SYIFA Borneo Journal of Pharmacy Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Kurniawati, Darini
Unknown Affiliation
Aerospace Engineering Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

Published : 46 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 46 Documents
Search

 1   2   3   4   5 
Uji Stabilitas dan Efektivitas Formulasi Serum Gel Ekstrak Bunga Melati (Jasmine sambac (L)) Sebagai Anti Jerawat: Stability and Effectiveness Test of Serum Gel Formulation of Jasmine Flower Extract (Jasmine sambac (L)) as an Anti Acne Malahayati, Siti; Kurniawati, Darini; Novianty, Nadya; Noval, Noval
Jurnal Surya Medika (JSM) Vol. 10 No. 2 (2024): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v10i2.7822

Abstract

Acne vulgaris atau yang biasa disebut jerawat merupakan masalah kulit berupa infeksi dan peradangan pada unit pilosebasea. Salah satu alternatif terapi yang sudah terbukti efektif untuk mengatasi jerawat berdasarkan uji pra klinik adalah bunga melati putih. Ekstrak bunga melati putih (Jasminum sambac l.) mampu menghambat pertumbuhan bakteri Propionibacterium acne. Penelitian ini bertujuan untuk melihat hasil stabilitas dan efektivitas formulasi sediaan serum gel ekstrak bunga melati sebagai anti jerawat. Metode yang digunakan dengan cara membuat konsentrasi ekstrak bunga melati yang berbeda-beda yaitu 12%, 13,5% dan 15% kemudian ketiga formula ini akan dilakukan uji efektivitas formula menggunakan nutrient agar dengan bakteri jerawat yaitu Propionibacterium acne, kemudian dilakukan uji stabilitas menggunakan metode stabilitas dipercepat dimana uji stabilitas dilakukan sebelum dan sesudah penyimpanan dengan suhu 40±20C dan RH 75% ± 5% menggunakan Climatic Chamber selama selama 30 hari dimana tiap sebelum dan sesudah penyimpanan dilakukan evaluasi yang meliputi uji pH, uji organoleptis, uji homogenitas, uji daya lekat, uji daya sebar, uji viskositas. Hasil yang diperoleh dianalisis secara statistik menggunakan metode Paired T-Test Hasil penelitian dari uji aktivitas antijerawat diperoleh hasil ekstrak bunga melati termasuk kategori antibakteri yang kuat. Hasil evaluasi pada semua formulasi memenuhi persyaratan uji pH, daya lekat, dan viskositas. Pada uji daya sebar formula 2 dan 3 memenuhi persyaratan, tetapi pada formula 1 tidak memenuhi persyaratan. Berdasarkan hasil penelitian formula 3 merupakan formula yang paling optimal dengan konsentrasi 15%.
Formulasi dan Stabilitas Sediaan Sabun Cair Ekstrak Kulit Jeruk Nipis (Citrus aurantifolia) Sebagai Antiseptik: Formulation and Stability Test of Liquid Soap Preparation of Lime Peel Extract (Citrus Aurantifolia) as an Antiseptic Sari, Putri Indah; Malahayati, Siti; Kurniawati, Darini
Jurnal Surya Medika (JSM) Vol. 10 No. 3 (2024): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v10i3.9007

Abstract

Antiseptik merupakan bahan atau zat yang mampu melindungi tubuh dari bakteri atau kuman yang menempel pada kulit. Oleh karena itu, diperlukan sediaan pembersih kulit serta dapat melindungi kulit dari paparan bakteri atau kuman yaitu sediaan sabun cair ekstrak kulit jeruk nipis (Citrus aurantifolia). Ekstrak kulit jeruk nipis (Citrus aurantifolia) memiliki kandungan senyawa flavonoid yang tinggi yang berfungsi sebagai antiseptik. Kelebihan dari sabun cair yaitu lebih higienis dan mudah dibawa. Penelitian ini bertujuan untuk mengetahui formulasi yang ideal dan stabilitas yang baik dari sediaan sabun ekstrak kulit jeruk nipis (Citrus aurantifolia). Penelitian ini menggunakan metode Quasy Experimental Design. Hasil penelitian menunjukkan bahwa uji organoleptis menghasilkan sabun cair warna jingga, aroma khas jeruk dan tekstur cair. Uji homogenitas semua formula dinyatakan homogen. Uji pH pada semua formula memenuhi persyaratan 4,5-5,5. Uji viskositas pada semua formula memenuhi persyaratan 400-4000 cPs. Uji tinggi busa semua formula memenuhi persyaratan 7-22 cm. Uji bobot jenis semua formula memeuhi persyaratan 1,01-1,10 g/ml. Uji asam lemak bebas semua formula memenuhi persyaratan mekasimal 0,14%. Simpulan dari ketiga formulasi tersebut yaitu formula yang ideal dan stabil terdapat pada formula I berdasarkan hasil data statistik dan evaluasi fisikokimia.
Aktivitas Antibakteri Ekstrak dan Fraksi N-Hexan Daun Benalu (Dendrophthoe Pentandra (L.) Miq.) Terhadap Pertumbuhan Bakteri Bacillus Subtilis dan Enterobacter Aerogenes : Antibacterial Activity of Ektract and N-Hexan of Benalu Leaves (Dendrophthoe Pentandra (L.) miq.) Against the Growth of Bacteria Bacilius Subtilis and Enterobacter Aerogenes Hepriana, Yemima; Nastiti, Kunti; Kurniawati, Darini; Hakim, Ali Rakhman
Jurnal Surya Medika (JSM) Vol. 10 No. 3 (2024): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v10i3.9071

Abstract

Tanaman Benalu (Dendrophthoe pentandra (L.) Miq.) merupakan salah satu kelompok tanaman yang dapat tumbuh liar, melekat menjadi parasit pada tanaman lain. Tanaman ini juga dapat dimanfaatkan sebagai antioksidan, antiinflamasi dan antibakteri. Mengetahui aktivitas antibakteri ekstrak dan fraksi n-Hexan daun Benalu (Dendrophthoe pentandra (L.) Miq.) terhadap pertumbuhan bakteri Bacillus subtilis dan Enterobacter aerogenes. Metode yang digunakan adalah True Experimental yang membagi ekstrak dan fraksi n-Hexan menjadi beberapa kelompok perlakuan yaitu konsentrasi ekstrak dan fraksi 25%, 50%, dan 100%, serta kontrol negatif dan kontrol positif. Pengujian potensi antibakteri menggunakan metode difusi cakram dengan mengukur diameter zona hambat yang terbentuk.Hasil uji aktivitas antibakteri terhadap Bacillus subtilis dengan konsentrasi ekstrak 50; 100% diameter zona hambat sebesar 16,72; 22,28 mm. Sedangkan, dengan konsentrasi fraksi 50; 100% diameter zona hambat sebesar 9,90; 19,00 mm. Hasil uji aktivitas antibakteri terhadap Enterobacter aerogenes dengan konsentrasi ekstrak 25; 50; 100% diameter zona hambat sebesar 14,49; 17,43; 22,52 mm. Sedangkan, dengan konsentrasi fraksi 25; 50; 100% diameter zona hambat sebesar 2,19; 17,46; 18,18 mm. Pada penelitian ini ekstrak mempunyai zona hambat yang lebih besar terhadap bakteri Bacillus subtilis dan Enterobacter aerogenes daripada fraksi n-Hexan pada seluruh konsentrasi yang diujikan.
P Profil Kromatografi Dan Penetapan Kadar Flavonoid Total Fraksi Etil Asetat Daun Kalangkala (Litsea Angulata Blum) Menggunakan Spektrofotometri Uv-Vis: Profil Kromatografi Dan Penetapan Kadar Flavonoid Total Fraksi Etil Asetat Daun Kalangkala (Litsea Angulata Blum) Menggunakan Spektrofotometri Uv-Vis Mardlatillah, Mardlatillah; Rohama, Rohama; Kurniawati, Darini
Jurnal Pelayanan Kefarmasian dan Sains Vol 4 No 1 (2023): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v4i1.276

Abstract

Background: Kalangkala is a fruit plant typical of Kalimantan and belongs to the species of the genus Litsea which is thought to have potential as a natural antioxidant. Empirically, some people in South Kalimantan use the kalangkala plant, especially the seeds of the fruit, to treat boils. One of the compounds that have antioxidant and antibacterial content is flavonoids.Objectives: To determine the thin layer chromatography profile of the total flavonoid compound of the ethyl acetate fraction and to calculate the total flavonoid content of the ethyl acetate fraction of the leaf extract of Kalangkala (Litsea angulata Blum).Method: Thin Layer Chromatography Profile and Determination of Total Flavonoid Content of the Ethyl Acetate Fraction of Kalangkala Leaf Extract using the UV-Vis Spectrophotometry method. The data were then analyzed qualitatively and quantitatively.Results: The chromatographic profile of the total flavonoids of the ethyl acetate fraction of Kalangkala leaf eluent that was most optimal was Ethyl acetate : n-Hexane (3:7) because it showed the most stains, namely 5 stains. And in the uv-vis spectrophotometry method, the total flavonoid content of the ethyl acetate fraction of Kalangkala leaves (Litsea angulata Blum) was 0.9 mg QE/g.Conclusion: Kalangkala leaf extract on the TLC profile using ethyl acetate : n-Hexane (3:7) showed a total of 5 stains. And the value of the total flavonoid content of the ethyl acetate fraction of kalangkala leaves was 0.9 mg QE/g.
E Etnomedicine Tumbuhan Obat di Masyarakat Desa Belangian, Kalimantan Selatan: Syahfitri, Laili Shinta Ayu; Nastiti, Kunti; Kurniawati, Darini; Rohama, Rohama
Jurnal Pelayanan Kefarmasian dan Sains Vol 4 No 2 (2024): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v4i2.549

Abstract

Background: The diversity of tribes and cultures in Indonesia makes culturaldifferences and traditional knowledge, one of which is in utilizing plants for thetreatment of a disease. One of the widespread tribes on the island of Kalimantanthat is thick with traditional medicine is the Banjar Tribe located in BelangianVillage, South Kalimantan. Ethnomedisin is a treatment by certain ethnicities basedon hereditary traditions in traditional medicine, in this case the use of medicinalplants.Objective: The purpose of this study was to determine the ethnomedicine ofmedicinal plants used by the Banjar Tribe of Belangian Village, Aranio District,South Kalimantan Province.Methods: This research is descriptive using qualitative and quantitative methods.Quantitative analysis with Fidelity Level (FL) calculations for each type ofmedicinal plant.Result: Based on the results of research from 38 informants, 58 species with 36families were obtained. There are 50 diseases that can be treated from 58 types ofmedicinal plants. The most popular method of processing is boiled 56.89 then drunk72.41%. The most widely used part of medicinal plants is the leaf part of 41.73%.Five types of plants with the highest FL values that stated effectiveness for treatmentwere Cymbopogon citratus 86.84%, Zingiber officinale 78.94%, Jatropha multifidaL 73.64%, Peronema canescens jack 68.42%, Syzygium polyanthum 65.78%. Thetradition of treatment with medicinal plants by the Banjar Tribe has been passeddown for generations with the value of local wisdom in its use.Conclusion: There are 58 types of medicinal plants that can be used as medicineor relief for certain diseases by the people of the Banjar Tribe, Belangian Village.With the highest FL value of five is found in Cymbopogon citratus plants 86.84%,Zingiber officinale 78.94%, Jatropha multifida L 73.64%, Peronema canescensjack 68.42%, Syzygium polyanthum 65.78%.
M Monitoring Efek Samping Obat Antihipertensi Di Puskesmas Kertak Hanyar Kabupaten Banjar Trisia, Trisia; Kurniawati, Darini; Nastiti, Kunti; Aryzki, Saftia
Jurnal Pelayanan Kefarmasian dan Sains Vol 5 No 2 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v5i2.720

Abstract

Background: Hypertension is a condition where blood pressure increases from normal or reaches 140/90 mmHg. In Indonesia, the prevalence of hypertension has increased, especially in South Kalimantan. The use of antihypertensive drugs is necessary to control blood pressure and is used long term, but it often causes side effects that can affect the patient's quality of life. So it is necessary to monitor drug side effects to monitor unwanted reactions after administering the drug. Objective: To identify the characteristics of patients who experience side effects and identify the incidence of side effects of antihypertensive drugs. Methods: The method used in this research is descriptive observational with a cross sectional design, and the sampling technique uses purposive sampling technique. The data collection instrument uses an observational sheet. Results: Based on the research results, it shows that the majority of respondents were aged 56-65 years (36.08%), female (55.70%), had elementary school education (36.72%) and worked as farmers (36.70%). The most widely used antihypertensive drug was single Captopril (44.30%) and there were 110 respondents (69.62%) who experienced drug side effects in the form of dry cough (47.27), swelling (23.63%), dizziness (16 .36%) and itching (12.72%). Conclusion: Based on the results of research conducted on 158 respondents, 110 reported experiencing drug side effects. The most commonly reported side effects are dry cough, swelling, dizziness and itching
Co-Authors Ahnafani, Mayada Nur Ahnafani, Miyada Nur Alfisah, Firda Ali Rakhman Hakim Ananda, Melin Sofia Anita Herawati, Anita Annisa Fitria Armilawati, Karien Fitria Aryani, Norsarida Aryzki, Saftia Bella Aprilia Punlin Charmelya, Estyvania Nur Ciky, Melsandra Daifa, Tri Masruratun Dewi Susanti Atmaja Diana Diana Esti Yuandari, Esti Fajriannor TM, M. Fitri Yuliana, Fitri Fuaddah, Munawarah Ganesa, Brianty Habibah, Nor Hanovani, Hanovani Hepriana, Yemima Iswandari , Novita Dewi Jayanti, Tri Dewi Kamelia citra, Mia Latif, Akmal Leluni, Adelia Lestari, Ema Harta Lestari, Helda Dwi Mahpujah, Maisya Malahayati, Siti Mardlatillah, Mardlatillah Marsellino, Doni Irawan Prancisco Melviani, Melviani Mia Audina, Mia Montella, Clara Muhammad Rifqi Mukti, Yusuf Anggoro Mustaqimah Mustaqimah Nafisa, Sherin Nasiroh, Nasiroh Nastiti, Kunti Noval Noval Novianty, Nadya NURUL HIDAYAH Nur’afa, Maulida Octavia, Mutia Octaviani, Via Panjaitan, Pungky Angeliana Putri Pawestri, Hasna Perdana, Ratna Dewi Wulandari Putri Pituwat, Cesilia Isana Putri, Marcelina Putri, Ni Luh Nadia Santika Rahmadani Rahmadani Raihana, Raihana Rakhman Hakim, Ali Redho Nugraha, Zen Achmad Rina Saputri Rohama, Rohama Rudiah, Siti Saftia Aryzki Salsabila, Tasya Salsa Sari, Intan Rahma Sari, Putri Indah Sary, Ariska Yulia Sismeri Dona, Sismeri Sri Suhartini Subhi Hartanto, Ahmad Ridho Surya Nata, Angelyna Syahfitri, Laili Shinta Ayu Syamsu, Erlina Tangkas, Hansel Hens Tania, Maria Amelinda Thong, Vertirico Trisia, Trisia Tuti Alawiyah Ulfah, Annisa Umi Hasanah, Umi Viviana, Viviana Wahyu Pangi Astuti, Ni Nyoman Winda, Nadia Oktavia Yuwindry, Iwan Zuraida Zuraida