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All Journal JURNAL KIMIA SAINS DAN APLIKASI Pharmaciana: Jurnal Kefarmasian Journal of Islamic Pharmacy JURNAL FARMASIMED (JFM) Jurnal Dunia Farmasi Jurnal Keperawatan Priority JURNAL PENELITIAN PERAWAT PROFESIONAL Jurnal Indah Sains dan Klinis Mejuajua JURNAL KIMIA SAINTEK DAN PENDIDIKAN Jurnal Pengmas Kestra (JPK) Pangripta Jurnal Ilmiah Kajian Perencanaan Pembangunan Jurnal Indah Sains dan Klinis Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Suprianto Suprianto
Institut Kesehatan Medistra Lubuk Pakam
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Economics, Econometrics & Finance Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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OPTIMASI FORMULA MATRIKS KITOSAN DENGAN METILSELULOSA PADA PELEPASAN TERKENDALI SEDIAAN GRANUL TEOFILIN Suprianto Suprianto
Jurnal Ilmiah Manuntung Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v1i2.22

Abstract

The in vitro study was carried out on the release of active ingradient theophylline from granules prepared by moist granulation method. The granule matrix was prepared from the mixture of chitosan isolated from SwaIIo shrimp (Metapenaeus monoceros) (in accordance with the Protan Laboratories, Inc standard requirement) and methylceliuiose 1500 cps. The granules were filled into 850 mg capsules containing 200 mg theophylline. The maximum weight of chitosan and methylcellulose for each capsule was determined by factorial design 22.The result showed that, when the amount of chitosan was kept constant, an increase in the amount of methylcellulose will increase the release rate of theophylline from granules. The optimum weight of chitosan and methyIceIIuIose are 609.24 mg and 20.00 mg, respectively for one capsule.
ANALISIS KINETIKA PELEPASAN TEOFILIN DARI GRANUL MATRIKS KITOSAN Suprianto Suprianto
Jurnal Ilmiah Manuntung Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v2i1.50

Abstract

Moment the drug dosage form development, it is important to study the drug release or dissolution that is recognized as an element in drug development. Mathematical models could help optimize the design of drugs to produce models of drug release information. Analysis of quantitative values obtained when depicting dissolution drug release profiles more easily when the mathematical concepts used to describe the drug release kinetics model. Model release of drugs known include zero order, first order, Higuchi models, models Hixon Crowell and Peppas Korsmeyer models. The purpose of this review apply mathematical concepts to study the phenomenon of drug release theophylline granules matrix made from chitosan
Penerapan Sanitasi dan Higienis dalam Pembuatan Jamu Gendong di Kota Tebing Tinggi Suprianto, Suprianto; De Lux Putra, Effendy; Nurbaya, Siti; Samran, Samran; Sumardi, Sumardi; Nasution, Derlina; Lestari, Wita
Mejuajua: Jurnal Pengabdian pada Masyarakat Vol. 4 No. 3 (2025): April 2025
Publisher : Yayasan Penelitian dan Inovasi Sumatera (YPIS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/mejuajuajabdimas.v4i3.220

Abstract

Jamu Gendong is a traditional drink that has the potential to be contaminated with worms, parasites, bacteria, fungi, viruses and rickettsia. Sources of contaminants include materials, equipment, facilities, personnel, animals and production environments, so their efficacy is questionable. The activity was carried out in the form of providing information on the implementation of sanitation and hygienic production to 38 Jamu Gendong traders in Tebing Tinggi City, Deli Serdang, North Sumatra. The material was delivered using illustrated power point media to facilitate the delivery of increased understanding of sanitation and hygiene, including objectives, benefits, programs, fixed procedures, disinfectant and washing materials as well as documentation in accordance with RI POM Regulation Number 31, 2022. Activities were carried out on April 29, 2024 and received positive responses from all participants. Activities are expected to be sustainable so that the Jamu Gendong produced is of higher quality.
Controlled release kinetics of furosemide from chitosan matrix tablets with hydroxypropyl methylcellulose phthalate coated Samran, Samran; Suprianto, Suprianto; Sumardi, Sumardi; Ritonga, Ahmad Hafizullah; Kusumastuti, Melati Yulia
Pharmaciana Vol. 14 No. 2 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i2.28097

Abstract

Sustained-release dosage forms were critical in drug delivery, ensuring controlled and prolonged release for optimal therapeutic outcomes. Chitosan (CH) has become pivotal in sustained-release tablet formulation due to its biocompatibility and mucoadhesive properties. This study aims to explore the release kinetics of furosemide (FS) from CH matrix tablets in a concurrent medium. The formulation involves a core tablet and coated tablet, with CH matrix as a binder and Hydroxypropyl Methyl Cellulose Phthalate (HPMCP) as a film-coated for the core tablet, and both are made using the wet granulation method. Assessment parameters include tablet hardness, disintegration, and FS release profiles across various media, analyzed using spectrophotometric methods to comprehend drug release kinetics with multiple models such as zero-order, first-order, Higuchi, and Korsmeyer-Peppas employed. In the press-coated tablet comprising core tablet CH as matrix uncoated with 20 mg CH per tablet core, a zero-order release pattern emerged in the pH 1.2 medium within 0-2 h, which displayed first-order release kinetics within 2-6 h and 6-16 h in concurrent media of pH 5.8 and 7.4. Notably, a zero-order release pattern emerged in the pH 1.2 medium within 0-2 h. Press-coated tablets incorporating CH matrix with HPCMP coated (CH-HPCMP), also containing 20 mg CH per tablet, exhibited diverse drug release kinetics. These tablets showed Korsmeyer-Peppas, zero-order, and first-order kinetics in pH 1.2, 5.8, and 7.4, respectively. The study suggests that a Press-coated tablet incorporating CH-HPMCP is suitable as the candidate for sustained-release formulations. The observed versatility in release kinetics across varying pH environments underscores the potential adaptability of these formulations in addressing diverse therapeutic needs.
Correlation of Education Level with Mother's Knowledge About the Nutritional Status of Stunted Toddlers Sitorus, Rotua Sumihar; Suprianto, Suprianto
Jurnal Keperawatan Priority Vol. 7 No. 1 (2024)
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jukep.v7i1.4472

Abstract

Chronic malnutrition due to prolonged malnutrition resulting in stunted growth and development. Educated and knowledgeable mothers have a big influence on the pattern of regulating balanced food needs for the growth and development of toddlers. The research was directed at determining the correlation between educated and knowledgeable mothers on the nutritional status of stunted toddlers in the Namorambe Community Health Center work area. Quantitative descriptive research was conducted cross-sectionally. The population was 32 mothers who had stunted toddlers (0-59 months) and the total was the sample. Univariate and bivariate analyzes were carried out to describe the frequency distribution of respondents' characteristics and determine the correlation between educated and knowledgeable mothers regarding the nutritional status of stunted toddlers. The results showed that mothers ranged from 20-30 years old and had upper secondary education as many as 25 (78.1%) and 21 (65.6%); toddler age 37-60 months, male gender, stunted toddler, and poor maternal knowledge were 16 (50%), 17 (53.1%), 22 (68.8%) and 23 (71.9%); and as many as 21 (65.6%) and 12 (37.5%) respondents had high school education and poor knowledge; as well as the Chi-square analysis results of p-value = 0.038, respectively. In the research, there was a correlation between educated and knowledgeable mothers on the nutritional status of stunted toddlers in the Namorambe Community Health Center work area.
FORMULASI SHEET MASK EKSTRAK ETANOL KULIT PISANG AMBON (Musa paradisiaca L.) SEBAGAI MOISTURIZING Adek Chan; Afriadi Afriadi; Hanafis Sastra Winata; Suprianto Suprianto; Sahrita Sahrita
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 7 No. 1 (2021): Jurnal Ilmiah Manuntung
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v7i1.424

Abstract

Ambon banana peel contains flavonoid chemical compounds that can moisturize facial skin. Flavonoids are powerful antioxidants. A sheet mask formulation of Ambon banana peel extract that can be used more practically and is able to moisturize facial skin. This study aims to formulate a mask sheet preparation containing ethanol extract of Ambon banana peel as well as better skin maintenance for four weeks of treatment and measuring the moisture content of the skin. The research method used is an experimental method, namely the extract is obtained using the maceration method, then formulated into a sheet mask preparation, consisting of glycerin, butylene glycol, sodium polyacrylate, nipagin, PEG-40 Hydrogenated Castrol oil, aquadest, perfume, and banana peel ethanol extract. Ambon with concentrations of F1 (1%), F2 (3%), F3 (5%), F4 (7%), F5 (9%), respectively. As blank (F0) sheet mask preparation without the addition of extract. The preparation is evaluated including homogeneity test, pH test, stability test, irritation test, Moisture effectiveness test using Moisture Checker and preference test. The treatment is carried out for 4 weeks by applying the mask twice a week. Data obtained from the analysis using the SPSS program. The results showed that the ethanol extract of Ambon banana peel can be formulated in a homogeneous sheet mask preparation, does not change color and remains stable in 4 weeks of storage with a pH of 4.6 - 6.6. Conclusion The ethanol extract of Ambon banana peel can be formulated into sheet masks with concentrations of 1%, 3%, 5%, 7% and 9% with a positive control ratio.
GSTAR Modeling for Forecasting Traffic Accident Claim Frequency as a Data-Driven Policy Instrument in Malang Raya Aisy, Auliya Hasna Rahadatul; Rahardjo, Swasono; Suprianto
PANGRIPTA Vol. 9 No. 1 (2026): Pangripta Jurnal Ilmiah Kajian Perencanaan Pembangunan
Publisher : Badan Perencanaan Pembangunan Kota Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58411/0zjx5281

Abstract

Traffic accidents represent one of the most persistent challenges of urban development, imposing a significant burden on public finances particularly through the compensation claim mechanism administered by PT Jasa Raharja. Understanding the spatial and temporal patterns of traffic accident claim frequency is a crucial foundation for local governments seeking to design effective data-driven policies. This study develops a forecasting model for traffic accident claim frequency across the Malang Raya area covering the Batu, Malang City, and Malang police jurisdictions using the Generalized Space-Time Autoregressive (GSTAR) approach as an analytical tool to support regional development planning. Monthly secondary data from PT Jasa Raharja Malang Branch covering January 2020 to March 2025 were used as the basis for modeling. The analysis proceeded through a series of systematic stages, including stationarity testing, spatial correlation and Cross Correlation Function (CCF) analysis, model identification, CCF-based spatial weight matrix construction, parameter estimation via the Seemingly Unrelated Regression (SUR) method, and residual diagnostic testing. Results indicate that the GSTAR(2,1) model successfully captures the spatio-temporal dependence structure across the three study regions, with the strongest spatial relationship identified between Batu and Malang City. Forecast results indicate that Malang consistently records the highest claim frequency, ranging from 70 to 85 claims per month. These findings carry strategic implications for local governments, the Department of Transportation, and other relevant stakeholders in optimizing resource allocation and designing more targeted and evidence-based traffic policy interventions.
Aplikasi Metode Penetapan Kadar Rutin Parasetamol PT. Kimia Farma, Tbk Secara HPLC pada Sediaan Tablet Generik dan Bermerek di Medan Suprianto; Darwin Syamsul; Muhammad Deddy Harfiansyah
Jurnal Indah Sains dan Klinis Vol 1 No 1 (2020): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/9abdjn64

Abstract

Paracetamol is a drug that is analgesic and antipyretic, which is produced as a generic or branded drug. The research objective was to determine the quality based on paracetamol levels in generic and branded tablet preparations circulating in Medan. The research used HPLC Alliance e2696 UV / Visible Detector 2489, Column µ Bondapak TMC-18: 10 µm 125A 3.9x300 mm, UV-Vis Spectrophotometer Agilent 8453. The method used was a routine assay method for paracetamol PT. Kimia Farma. The results showed that the paracetamol content in the tablet dosage was 97.05% - 106.04%, according to the Indonesian Pharmacopoeia Edition V, not less than 90% and not more than 110%.
Korelasi Faktor Pemicu Kebiasaan Jajan Anak SD Al Khairiyah di Kecamatan Sunggal Kabupaten Deli Serdang Nur Asni Arti; Suprianto Suprianto
Jurnal Indah Sains dan Klinis Vol 1 No 1 (2020): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v1i1.2

Abstract

Behavior originates from the impulse in humans which is an effort to meet human needs. Eating behavior that is often a problem is eating habits in canteens or stalls around school and eating fast food habits. The role of snacks in contributing energy or energy and protein substances is very significant, considering that school children get less protein intake and often snack, it is better if the snacks sold in the school canteen are high protein foods.This study aims to determine the factors associated with habitual snacking behavior. This was a non-experimental study through survey and observational approaches with a cross sectional sample of 96students. Data collection includes eating habits, nutritional knowledge, breakfast habits, breakfast frequency, food carrying habits, pocket money, and types of food obtained through questionnaires. The data analyzedusing Chi Square test.There area relationship between nutritional knowledge, breakfast habits, carrying food, pocket money, and types of snacks with the snack habits of Al-Khairiyah Elementary School children, Sunggal District, Deli Serdang Regency. All factors are related to eating habits
Efektifitas Lotion Anti Nyamuk Ekstrak Etanol Daun Kenikir (Cosmos caudatus) Suprianto; Hendri Faisal; Endang Subekti
Jurnal Indah Sains dan Klinis Vol 2 No 1 (2021): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v2i1.9

Abstract

Mosquitoes are one of those insects with an often annoying presence. Saponins, polyphenols, and essential oils are found in the Kenikir plant (Cosmos caudatus). Experimental research was conducted with tests covering: organoleptic, homogeneity, pH, and effectiveness. Organoleptic lotions at concentrations of 5%, 10% and 15% have a dark green colour with a distinctive odour of Kenikir. Lotions with a concentration of 5% are homogeneous, while at concentrations of 10% and 15% are not homogeneous. Organolepticrequirements and homogeneity as lotions are met. The results obtained showed that the Kenikir leaf extract was effective at repelling mosquitoes.
Co-Authors Abdul Rahim Adek Chan Adek Chan Adek Chan Adek Chan Afriadi Afriadi Ahmad Hafizullah Ritonga Aisy, Auliya Hasna Rahadatul Alam Suhada Alam Suhada Alizha Aisyah Ananda Sri Devy Ancel Mus Silaban Andilala Andraini, Galuh Anita Anita Anjur Falden Lingga Annas Reza Annas Reza Ardina Ardina Ardina Pakpahan Arifin Putra Zai Arinri Misnangin Sritala Ramadani Arinri Misnangin Sritala Ramadani Atika, Nur BENNI ISKANDAR Chan, Adek Cut Fatimah Cut Fatimah Darwin Syamsul De Lux Putra, Effendy Debi Meilani Debi Melani Derlina . Devi Purnama Sari Dewi Kartika Dewi Sartika Munthe Dian Zulkarnain Lubis Dikari Harita Dwi Setio Purnomo Dwi Setio Purnomo Elvy Oktima Elvy Oktima Endang Subekti Endang Subekti Enny Fitriani Febriady, Andy Fesri Damai Riang Laia Fesri Damai Riang Laia Fina Dheny Lantika Fitri Mayang Sari Fitriani Nasution Fitriani, Enny Fridelly Mairani Hasrat Masa Harefa Hendri Faisal Hendri Faisal Herliana Herlina H Herlina Herlina Hermansyah . Hetty Wahyuni Ihsanul Hafiz Indra Ginting Jakub Tarigan Jakub Tarigan Jelly Syahfitri Johannes Johannes Joko Wibowo Kurniawansyah, Kurniawansyah Kusumastuti, Melati Yulia Leny, Leny Lestari, Wita Lili Nurmaliza Lukmanul Hakim M. Deddy Harfiansyah Maelani, Mia Mandike Ginting Mandike Ginting Maya Annisa Lubis Maya Sartika Maya Sartika Melati Yulia Kusumastuti Melati Yulia Kusumastuti Muhammad Gunawan Muhammad Gunawan Muhammad Gunawan Nasution, Lely Fitri Handayani Nilsya Febrika Zebua Zebua Nilsya Febrika Zebua, Nilsya Febrika Nur Aisyah Pitri Nur Asni Arti Nur Asni Arti Nurasyah Nurasyah Nurlela Petra Saragih Nur’Adina Nur’Adina Nur’Adina Peri Aisyah Zubaidi Pranata, Chandra Putri Addina Rachel Anastasia R Hutabarat Regina Elianda Tambubolon Risma Yeni Rotua Sumihar Sitorus Ruseni Ruth Mayana Rumanti Ruth Mayana Rumanti Safitri Saragih Sahrita Sahrita Samran, Samran Sefryantonius Lase Sertin Prilda Sari Sandoro Sertin Prilda Sari Sandoro Shofian Syarifuddin Sindy Andriani Siregar, Riwandi Siti Fatimah Hanum Siti Fatimah Hanum Siti Nurbaya Sri Handayani Sri Rahayu Sri Rahayu Suci Rahmadani Siregar Sucihati, Roos Nana Sudiyarti, Nining Suhendra Tawarnate Sumardi Sumardi Sumardi Sumardi Sumardi Sumardi . Sumardi Sumardi Swasono Rahardjo Syamsul, Darwin Vivi Eulis Diana Vivi Eulis Diana Wandani, Elliza Rizki Wilda Rizwani Winata, Hanafis Sastra Yade Metri Permata