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Aplikasi Metode Penetapan Kadar Rutin Parasetamol PT. Kimia Farma, Tbk Secara HPLC pada Sediaan Tablet Generik dan Bermerek di Medan Suprianto; Darwin Syamsul; Muhammad Deddy Harfiansyah
Jurnal Indah Sains dan Klinis Vol 1 No 1 (2020): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/9abdjn64

Abstract

Paracetamol is a drug that is analgesic and antipyretic, which is produced as a generic or branded drug. The research objective was to determine the quality based on paracetamol levels in generic and branded tablet preparations circulating in Medan. The research used HPLC Alliance e2696 UV / Visible Detector 2489, Column µ Bondapak TMC-18: 10 µm 125A 3.9x300 mm, UV-Vis Spectrophotometer Agilent 8453. The method used was a routine assay method for paracetamol PT. Kimia Farma. The results showed that the paracetamol content in the tablet dosage was 97.05% - 106.04%, according to the Indonesian Pharmacopoeia Edition V, not less than 90% and not more than 110%.
Korelasi Faktor Pemicu Kebiasaan Jajan Anak SD Al Khairiyah di Kecamatan Sunggal Kabupaten Deli Serdang Nur Asni Arti; Suprianto, Suprianto
Jurnal Indah Sains dan Klinis Vol 1 No 1 (2020): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v1i1.2

Abstract

Behavior originates from the impulse in humans which is an effort to meet human needs. Eating behavior that is often a problem is eating habits in canteens or stalls around school and eating fast food habits. The role of snacks in contributing energy or energy and protein substances is very significant, considering that school children get less protein intake and often snack, it is better if the snacks sold in the school canteen are high protein foods.This study aims to determine the factors associated with habitual snacking behavior. This was a non-experimental study through survey and observational approaches with a cross sectional sample of 96students. Data collection includes eating habits, nutritional knowledge, breakfast habits, breakfast frequency, food carrying habits, pocket money, and types of food obtained through questionnaires. The data analyzedusing Chi Square test.There area relationship between nutritional knowledge, breakfast habits, carrying food, pocket money, and types of snacks with the snack habits of Al-Khairiyah Elementary School children, Sunggal District, Deli Serdang Regency. All factors are related to eating habits
Efektifitas Lotion Anti Nyamuk Ekstrak Etanol Daun Kenikir (Cosmos caudatus) Suprianto; Hendri Faisal; Endang Subekti
Jurnal Indah Sains dan Klinis Vol 2 No 1 (2021): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v2i1.9

Abstract

Mosquitoes are one of those insects with an often annoying presence. Saponins, polyphenols, and essential oils are found in the Kenikir plant (Cosmos caudatus). Experimental research was conducted with tests covering: organoleptic, homogeneity, pH, and effectiveness. Organoleptic lotions at concentrations of 5%, 10% and 15% have a dark green colour with a distinctive odour of Kenikir. Lotions with a concentration of 5% are homogeneous, while at concentrations of 10% and 15% are not homogeneous. Organolepticrequirements and homogeneity as lotions are met. The results obtained showed that the Kenikir leaf extract was effective at repelling mosquitoes.
Potensi Antibakteri Kombinan Zingiber officinale var. Rubrum dengan Cinnamomum burmannii terhadap Staphylococcus aureus Ruth Mayana Rumanti; Suprianto; Jakub Tarigan; Arinri Misnangin Sritala Ramadani
Jurnal Indah Sains dan Klinis Vol 2 No 1 (2021): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v2i1.8

Abstract

Red Ginger (Zingiber officinalevar. Rubrum) and Cinnamon (Cinnamomum burmannii) contain alkaloids, flavonoids, saponins, tannins, triterpenoids and essential oils. which is antibacterial that causes pharyngitis by Staphylococcus aureus. This study aims to determine the antibacterial potency of the combination of Red Ginger (Zingiberofficinalevar. Rubrum) and Cinnamon (Cinnamomum burmannii) extract against Staphylococcus aureus. Experimental research includes the extraction of the compound components in red ginger and cinnamon by maceration with 70% ethanol. Inhibition was tested bydiffusion method. Combination of concentration of Red Ginger and Cinnamon extracts of 5%:40%; 10%:30%; 20%:20%; 30%:10% and 40%:5%. The combination of red ginger and cinnamon extract has antibacterial activity against pharyngitis-causing bacteria, namely Staphylococcus aureuswith a strong response at a concentration of 5%:40%
Kompleksometri Kalsium dan SSA Timbal Beberapa Depot Air Isi Ulang di Medan Nur’Adina; Hendri Faisal; Suprianto
Jurnal Indah Sains dan Klinis Vol 2 No 2 (2021): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v2i2.19

Abstract

Calcium minerals play an important role in maintaining body functions, while Lead is a dangerous heavy metal. The research was aimed at determining the levels of Calcium and Lead from several refill water depots in Medan. Calcium complexometry and lead AAS as their respective assay methods. Research shows calcium levels are 10.3-29.3 mg/L, correlation coefficient is 0.9928, and no lead is found in refill drinking water. Calcium levels do not meet the requirements, while lead levels still meet the WHO requirements.
Formulasi Sediaan Eyebrow Cream Arang Aktif Batok Kelapa Sertin Prilda Sari Sandoro; Suprianto; Sumardi
Jurnal Indah Sains dan Klinis Vol 2 No 2 (2021): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v2i2.26

Abstract

Eyebrow cream (EC) is one of the decorative cosmetics applied to the eyebrows using a brush for the purpose of giving color and emphasizing the shape of the eyebrows. EC is one of the practical preparations to fill in empty eyebrow hairs. The research was conducted of formulating activated charcoal into EC. The research method includes the formulation and evaluation of EC results from coconut shell activated charcoal at concentrations of activated charcoal 1%, 3%, 5% and 7%. Evaluation includes: organoleptic, homogeneity, irritation and pH of Eyebrow Cream. The organoleptic showed that the color of the preparation at a concentration of 1% -7% was black to dark black, with a cocoa oleum aroma, and a semi-solid texture. The pH of the preparation is 4.5-6.5 with good homogeneity. The preparation did not show irritation to the skin of volunteers. The study provide information that activated charcoal can be formulated into EC preparations. Coconut shell activated charcoal can be formulated in the form of eyebrow cream. The preparation of eyebrow cream does not cause irritation and is safe.
Tablet Kompresi Langsung Ekstrak Etanol Daun Salam (Syzygium polyanthum) Muhammad Gunawan; Suprianto; Samran; Cut Fatimah; Debi Melani; Sumardi
Jurnal Indah Sains dan Klinis Vol 2 No 3 (2021): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v2i3.31

Abstract

Indonesia's natural wealth that is efficacious in suppressing cholesterol, hypertension, diarrhea, gastritis and blood sugar is one of the bay leaves (Syzygium polyanthum Wight.). Tablets are preparations that are practical to use, easy to produce, pack, and distribute. The research was directed to make tablets of bay leaf ethanol extract (EEDS) by direct compression. EEDS tablets were made into four formulas with various fillers of lactose and Avicel PH 102, each 200 mg : 135 mg A); 250 mg : 105 mg (B); 300 mg : 55 mg (C); and 350 mg : 5 mg (D). The study showed that all formulas met the preformulation test requirements and tablet evaluation, D as the best formula. EEDS is made into tablets by direct compression.
Analisa Vitamin C dan Evaluasi Sediaan Tablet Effervescent Campuran Ekstrak Etanol Biji Jambu Biji Merah dan Putih (Psidium guajava L.) Hendri Faisal; Suprianto; Nur Aisyah Pitri; Sri Handayani; Dwi Setio Purnomo
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i1.40

Abstract

Effervescent tablets, CO2-producing tablets from the reaction of tablet constituents with their solvents. Red guava contains beta-carotene vitamin C is quite high, white guava is rich in vitamins, flavonoids, carotenoids, saponins, tannins, phenols, triterpenes, essential oils, fiber, and fatty acids. The study aimed at the comparison of vitamin C extract of red and white guava seeds (Psidium guavala. L). Powder evaluation includes flow time, angle of repose, compactibility. The evaluation of tablets included organoleptic, soluble time, weight uniformity, hardness, friability, pH, vitamin C content using UV spectrophotometry method. The results showed that the flow time test was 11.31-16 gram/second, the angle of repose was 33.02-34.92%; compactibility 7.59-16.9%; effervescent tablet preparation is round in shape, brown aroma, dark brown-brown color, slightly sweet taste, dissolving time 33.79- 89.53 seconds; hardness 4-5,4 kg; friability 0.04-0.9%; pH is close to neutral at pH 5.83-6.39; vitamin C content of red and white guava seeds were 37.86 mg/g and 42.32 mg/g, respectively. Red and white guava seed extract can be formulated into effervescent tablets and has vitamin C 0.19 – 0.28 mg/g
Evaluasi Stabilisator Agar-Agar dan CMC Sediaan Sirup Markisa Berastagi Suprianto; Muhammad Gunawan; Melati Yulia Kusumastuti; Cut Fatimah; Debi Meilani
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/b1pzvs47

Abstract

Fruit syrup is made from a sugar solution, the taste and aroma are determined by the freshness of the fruit. Fruit commonly used in making syrup has an attractive color, aroma and distinctive taste. Passion fruit (Passiflora edulis Sims.) has a distinctive taste and aroma, so it is widely processed into syrup. This study was to evaluate CMC and Agar-Agar stabilizers in the passion fruit syrup formula. Evaluation includes color, appearance, texture, taste and aroma and hedonic tests are carried out. The results showed that there were significant differences in the color, appearance, texture, taste and aroma of passion fruit syrup. Stabilizers CMC and Agar-Agar make the color, texture and appearance of the syrup better and more attractive. The result of hedonic test for ideal syrup concentration is S3 with 4 g of Agar and 6 g of CMC. The higher the concentration of CMC and Agar, the greater the viscosity of the syrup. The concentration of CMC and Agar-agar in a mixture of fruit juices gave significantly different effects on color, texture, appearance, taste and aroma
Formulasi dan Evaluasi Sediaan Sabun Padat Antiseptik Ekstrak Etanol Daun Kunyit Suprianto; Sumardi; Debi Meilani; Sri Rahayu
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i1.44

Abstract

The plant of findings turmeric (Curcuma longa) are often used as a traditional medicinal. The part of the turmeric plant that is often used is the rhizome. In addition to turmeric rhizome, turmeric leaves are also used as a flavoring dish. Among the benefits of turmeric leaves is as an antimicrobial. Soap is a surfactant used for washing and cleaning. Antiseptics are inhibitors for the growth and development of microorganisms that live on the surface of the body. The study was to determine which ethanol extract of turmeric leaves could be formulated into antiseptic solid soap preparations. This study used an experimental method, turmeric leaves were extracted with 70% ethanol. The formula made are 2.5%, 5%, 7.5%. The quality of the soap preparation was carried out by organoleptic tests, acidity, high foam and irritation. The results test showed that the solid soap did not have the aroma of turmeric leaves, the pH of the soap was 9.9-10.5; foam height with a concentration of 7.5% which is 7.3 cm; and solid soap preparations ethanol extract of turmeric leaves did not cause irritation. The extract of turmeric leaves can be formulated into solid soap preparations. It is recommended to add perfume to the formulation of solid soap preparations of turmeric leaf extract as an antiseptic.
Co-Authors A., Ade Ayu Fitriana Abdul Rahim Adek Chan Adinda Seftia Afriadi Afriadi Agung Ardiansyah, Agung Agus Kristina Ahmad Hafizullah Ritonga Ahmad Sumantri - Alam Suhada Alam Suhada Alizha Aisyah Amal Said Ananda Sri Devy Ancel Mus Silaban Andilala Andraini, Galuh Andy Febriadi Anita Anita Anjur Falden Lingga Annas Reza Annas Reza Ardina Ardina Ardina Pakpahan Arinri Misnangin Sritala Ramadani Arinri Misnangin Sritala Ramadani Atika, Nur Atmaja, Hengki Atmanegara, Akhmad Prasetya Azzahra, Innayah Bagus Bagus, Bagus BENNI ISKANDAR Bimantoro, Zurdan Budi Harianto, Budi Bunda, Yola Permata Chan, Adek Chandra Pranata Cut Fatimah Cut Fatimah Cyndi Veronica Darmawati Darmawati De Lux Putra, Effendy Debi Meilani Debi Melani Derlina . Devi Purnama Sari Dewi Kartika Dewi Sartika Munthe Dian Zulkarnain Lubis Didi Darmadi, Didi Dikari Harita Dwi Setio Purnomo Effendy De Lux Putra Elvy Oktima Elvy Oktima Endang Subekti Endang Subekti Enny Fitriani Fadilasyah, Dimas Afrizal Fahmi, Muhammad Ikhwan Febriady, Andy Fesri Damai Riang Laia Fesri Damai Riang Laia Fina Dheny Lantika Fitri Mayang Sari Fitriani Nasution Fitriani, Enny Fridelly Mairani Apt Hafiz Luthfi Hasrat Masa Harefa Helda Ibramin Hendri Faisal Henry Toruan - Herliana Herlina H Herlina Herlina Herman Jufri Andi, Herman Jufri Hermansyah . Hermawan, Love Retno Herri Trisna Frianto, Herri Trisna Herwin Herwin, Herwin Hery Novpriansyah Hetty Wahyuni Hidayani, Mesalina Tri Ihsanul Hafiz Indra Ginting Jakub Tarigan Jakub Tarigan Jelly Syahfitri Johannes Johannes Joko Wibowo Kresna Shifa Usodri Kurniawansyah, Kurniawansyah Kusumastuti, Melati Yulia Leny, Leny Lestari, Wita Lidiya Sasmaita Sihotang Lili Nurmaliza Lisa Syafrida Lukmanul Hakim Luluk Widarti Maelani, Mia Manalu, Joko C.H Mandike Ginting Mandike Ginting Marbun, Intan Coni Caroline Maya Annisa Lubis Maya Sartika Maya Sartika Meidi Wani Lestari, Meidi Wani Melati Yulia Kusumastuti Melati Yulia Kusumastuti Muhammad Deddy Harfiansyah Muhammad Deddy Harfiansyah Muhammad Fadlan Siregar Muhammad Gunawan Muhammad Gunawan Nadiya Arifa Rahma Nainggolan, Angel M. Nasution, Lely Fitri Handayani Nilsya Febrika Zebua, Nilsya Febrika Nindha Ayu Berlianti Nur Afni Afrianti Nur Afni Afrianti Nur Aisyah Pitri Nur Asni Arti Nur Asni Arti Nurasyah Nurasyah Nurlela Petra Saragih Nur’Adina Nur’Adina Nur’Adina Peranginangin, Siwan Edi A. Peri Aisyah Zubaidi Permata, Yade Metri Pranata, Chandra Prasetiyo, Bagus Prayoga, Mirza Kirma Putri Addina Rachel Anastasia R Hutabarat Rahmawati, Eka Fauziah Ramly, Amisbah Rante, Neli Riany, Meutia Risma Yeni Roby Fernandi Rotua Sumihar Sitorus Rusdi Evizal Ruseni Ruth Mayana Rumanti Ruth Mayana Rumanti S. Ida Kholida Sadewa, Wahyu Digda Sahrita Sahrita Salim, Helmi Agus Samran, Samran Saragih, Safitri Sefryantonius Lase Sertin Prilda Sari Sandoro Sertin Prilda Sari Sandoro Shofian Syarifuddin simanjuntak, benrad edwin Simarmata, Aditya D Sindy Andriani Siregar, Riwandi Siregar, Suci Rahmadani Siringoringo, Michael R.S. Siti Fatimah Hanum Siti Maemonah Siti Nurbaya Siti Nurbaya Sitorus, Irfan Sri Handayani SRI RAHAYU Sri Rahayu Sri Wulandari Sri Yusnaini Sucihati, Roos Nana Sudiyarti, Nining Suhendra Tawarnate Sumardi Sumardi Sumardi . Syahputra, Syofyan Anwar Syamsul, Darwin Tambubolon, Regina Elianda Tandaditya Ariefandra Airlangga Tinambunan, Lukas A. Vivi Eulis Diana Vivi Eulis Diana Wandani, Elliza Rizki Wenehenubu, Fitalis Ekhy Wilda Rizwani Winata, Hanafis Sastra Zaenuddin Hudi Prasojo Zai, Arifin Putra Zaqyah, Irene Zebua, Nilsya Febrika Zebua