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All Journal JURNAL KIMIA SAINS DAN APLIKASI Jurnal Ilmu Dasar Jurnal Sains dan Teknologi Pharmaciana: Jurnal Kefarmasian Journal of Islamic Pharmacy Turbo : Jurnal Program Studi Teknik Mesin Jurnal Pendidikan dan Ilmu Geografi Jurnal Ilmiah Manuntung KACANEGARA Jurnal Pengabdian pada Masyarakat PeTeKa JURNAL PENJAKORA JURNAL FARMASIMED (JFM) Jurnal Dunia Farmasi Jurnal Keperawatan Priority Jurnal Pengabdian Masyarakat Sains Indonesia (Indonesian Journal Of Science Community Services) Community Engagement and Emergence Journal (CEEJ) JURNAL PENELITIAN PERAWAT PROFESIONAL Jurnal Pembelajaran Pemberdayaan Masyarakat (JP2M) Journal of Computer Networks, Architecture and High Performance Computing Jurnal Disrupsi Bisnis Masjiduna : Junal Ilmiah Stidki Ar-Rahmah Jurnal Indah Sains dan Klinis Indonesian Journal of Society Engagement (IJSE) Jurnal Teknik Elektro (JTE) Jurnal Penelitian Inovatif Mejuajua Jurnal Kajian Ruang JPIG East Asian Journal of Multidisciplinary Research (EAJMR) Eksergi: Jurnal Teknik Energi Sinergi Polmed : Jurnal Ilmiah Teknik Mesin Lensa: Jurnal Kependidikan Fisika JURNAL KIMIA SAINTEK DAN PENDIDIKAN Jurnal Ekonomi dan Bisnis Samalewa: Jurnal Riset dan Kajian Manajemen Jurnal Mahasiswa Mengabdi (JIMAWAbdi) Jurnal Pengmas Kestra (JPK) Journal of Social Science Jurnal Manajemen Riset Inovasi Jurnal Intelek Dan Cendikiawan Nusantara JGEN : Jurnal Pengabdian Kepada Masyarakat Jurnal Indah Sains dan Klinis Jurnal Manajemen & Pendidikan Proceeding Of International Conference On Education, Society And Humanity Journal of Social Sciences and Economic Journal of Public Policy and Regional Government (JPPLG) Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Global Ten Public Health and Nursing Journal Jurnal Elektronik Pendidikan Matematika Tadulako Jurnal Ad'ministrare: Jurnal Pemikirian Ilmiah dan Pendidikan Administrasi Perkantoran Indonesian Journal of Advocacy and Legal Services International Journal of Advances in Artificial Intelligence and Machine Learning EL-HAYAH
Suprianto Suprianto
Institut Kesehatan Medistra Lubuk Pakam
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Uji Kemurnian Ekstrak Galaktomanan Biji Durian (Durio zibethinus L.) dengan Metode Luff Schoorl Zebua, Nilsya Febrika; Sumardi; Suprianto; Alizha Aisyah
Jurnal Indah Sains dan Klinis Vol 3 No 3 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i3.01

Abstract

Introduction: Galactomannan is found in the endosperm of seeds in the Fabaceae family, for example durian seeds (Durio zibethinus L). Galactomannan is a natural polysaccharide as an additional ingredient. Objective: The research aims to determine the Galactomannan content in Durian seeds isolated by chromatography and to determine the Galactomannan content in Durian seeds using the Luff Schoorl method. Methods: The research was carried out by extracting galactomannan from Durian seeds using distilled water by heating them for 5 minutes. Purification was carried out using paper chromatography with various variations of mobile phases, namely BEW (Butanol: Ethanol: Water), BAW (Butanol: Acetic acid: Water), Glacial acetic acid 10%, Glacial acetic acid 50%, HCl 10%, HCl 20% and Thin layer chromatography with the mobile phase n-Hexane: Ethylacetate at varying ratios of 3:7 and 7:3. Purity testing is carried out using the Luff Scroorl method. Results: Extraction of 500 g of durian seeds produces 1,8% Galactomannan. The levels before and after inversion using the Luff Schoorl method were respectively 8.0131 and 7.0679 mg/mg. Conclusion: Galactomannan can be obtained from extracting durian seeds and its inverse using the Luff Scroorl method.
Analisis Kadar Kalsium, Kalium, Besi Akibat Variasi Waktu Rendam Kacang Produksi Susu Almond secara Spektrofotometri Serapan Atom Yade Metri Permata; Suprianto; Ananda Sri Devy
Jurnal Indah Sains dan Klinis Vol 3 No 3 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i3.02

Abstract

Background: Calcium, potassium and iron can be obtained from milk, nuts, eggs, fish, fruit vegetables, green vegetables and products needed by the human body which play a role in maintaining body functions, including cells, tissues, organs and overall function. Objective: Research to determine the levels of these minerals in almond milk using atomic absorption spectrophotometry (AAS). Method: Almonds were soaked for 4, 8, and 12 hours respectively for almond milk 1, 2, and 3 (SA1, SA2, and SA3) and Almendrola packaged milk (SA4). Samples were wet digested with concentrated HNO3. Analysis of calcium, potassium and iron levels using AAS with an air-acetylene flame was 422.7; 766.5; and 248.3 nm for calcium, potassium and iron respectively. Validated methods include accuracy, precision, LOD and LOQ. Results: Results of determining the mineral content of almond milk (mg/100g) for calcium, potassium and iron respectively (2.6551 ± 0.0925; 5.5464 ± 0.3178; 5.8866 ± 0.03805; and 4.5842 ± 0.2590), (2.4096 ± 0.0551; 2.5150 ± 0.0115; 2.6551 ± 0.0557; and 2.5150 ± 0.0551), and (0.3202 ± 0.0282; 0.3307 ± 0.0048; 0.3344 ± 0.011; and 0.3183 ± 0.0045). Conclusion: Validation of the method meets the requirements, soaking impacts increasing mineral levels in Almond Milk, and there are significant differences in calcium, potassium and iron levels in the milk.
Optimasi Potensi Anti Escherichia coli dan Staphylococcus aureus Kombinasi Ekstrak Etil Asetat Allium cepa dan Allium sativum Suprianto; Dikari Harita; Dwi Setio Purnomo
Jurnal Indah Sains dan Klinis Vol 4 No 1 (2023): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v4i1.01

Abstract

Background: Natural antibiotics are often used as an alternative therapy. Microbial infections are the main cause of mortality and morbidity in developing countries, including Indonesia. Staphylococcus aureus and Escherichia coli are two microbes that are often used for testing natural antibiotics. Objective: This study aims to optimize the combination of shallot and white onion extracts to potentially inhibit bacterial growth and development. Method: This study used a randomised design method of a combination of onion and garlic extracts tested based on the inhibitory area response. Results: The combination of shallot and white onion ethyl acetate extracts showed activity as an inhibitor of bacterial growth and development. The combination of EBM and EBP provides an inhibitory response against Escherichia coli (X2) and Staphylococcus aureus (X3). Conclusion: Combining EBM and EBP can inhibit the growth and development of Escherichia coli and Staphylococcus aureus. The best combination as an inhibitor of growth and development was Escherichia coli (X2; 14.53 mm) and Staphylococcus aures (X3: 15.7 mm), respectively
Gambaran Pemakaian Bahan Medis Habis Pakai Gudang Depo Farmasi Rindu B RSUP H. Adam Malik Medan Berdasarkan Standar Operasional Prosedur Tahun 2019 Anjur Falden Lingga; Adek Chan; Suprianto
Jurnal Indah Sains dan Klinis Vol 4 No 2 (2023): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v4i2.02

Abstract

Introduction: Managing consumable medical materials involves coordinating activities to ensure they work well together, aiming for effective and efficient management. This ensures doctors always have an adequate supply of high-quality consumable medical materials to support quality services. Objective: This study aimed to describe the Utilization of Consumable Medical Materials at the Pharmacy Warehouse of Depo Rindu B H. Based on the 2019 Standard Operating Procedures (SOP), Adam Malik Hospital Medan. Methods: The study utilized direct observation and interviews conducted from May to July 2019. Results: Expenditures in January, February, and March 2019 were 25,726, 22,332, and 24,503 units respectively. Distribution is facilitated through online prescribing and delivery. Observations indicated the use of storage systems such as First In First Out (FIFO) and First Expired First Out (FEFO), organised by dosage form, alphabetical order, and category. Conclusion: Procurement at the Depo Rindu B pharmaceutical warehouse at H. Adam Malik Hospital Medan during the 2019 period was by the applicable 2019 SOP
Analisis Farmakokinetik Klinik Dosis Obat Pasien Hipertensi Komplikasi Gagal Di RSUD Dr. Pirngadi Medan Zebua, Nilsya Febrika; Peri Aisyah Zubaidi; Sumardi; Suprianto; Shofian Syarifuddin; Risma Yeni
Jurnal Indah Sains dan Klinis Vol 4 No 1 (2023): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v4i1.06

Abstract

Background: Hospitals are health service providers providing emergency care, outpatient and inpatient. Hypertension occurs when blood pressure is above normal. Clinical conditions that require dialysis treatment have a tendency to kidney failure. This effort is related to the field of clinical pharmacokinetics. Objective: The study was conducted to analyze the dose of drug administration in conditions complicated by kidney failure in hypertensive patients. Methods: The study went through a sampling stage of data from hypertensive patients complicated by kidney failure, data according to inclusion criteria, calculation of creatinine clearance, analysis of dose adjustments and creatinine clearance. Results: The study obtained 170 data, which met the inclusion criteria of 30 data. Drugs with a narrow therapeutic index and worsening kidney function that patients received included: digoxin, captopril, ranitidine, furosemide, ciprofloxacin, and cefriaxone in 2, 13, 9, 12, 3, and 8 cases respectively. Conclusion: According to dose adjustment calculations for patient creatinine clearance, it was found that the drug exceeded the individual dose in 6 out of 9; 8 of 13; and 2 cases each using ranitidine, captopril, digoxin
Hubungan Pengetahuan dan Sikap Kaum Ibu Punge Blang Cut-Jaya Baru pada Preventivasi Demam Berdarah Lukmanul Hakim; Adek Chan; Suprianto; Vivi Eulis Diana
Jurnal Indah Sains dan Klinis Vol 4 No 2 (2023): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v4i2.04

Abstract

Background: According to the World Health Organization, annually there are around 50.0-100.0 million cases of dengue fever worldwide, with 0.25-0.50 million of them being cases of dengue hemorrhagic fever (DHF) which causes around 24,000 death. Objective: The study was directed at evaluating the knowledge and attitudes of mothers regarding dengue prevention in Punge Blang Cut, Jaya Baru. Method: A cross-sectional design was used in the study conducted in April 2019. Around 176 heads of families in the village were sampled. Data was collected through a questionnaire with the Chi-Square test at a significance of 0.05. Results: The majority of respondents had sufficient knowledge (46.6%), their mothers had a positive attitude towards dengue prevention (73.3%), and 52.3% of respondents took sufficient preventive measures. Conclusion: The majority of mothers have sufficient knowledge and have a positive attitude towards preventing dengue fever. It is recommended to increase public knowledge and awareness regarding the handling and prevention of dengue fever through appropriate medical and traditional methods.
Kuantifikasi Inversi Galaktomanan Kolang-Kaling (Arenga pinnata Merr.) dengan Iodometri Zebua, Nilsya Febrika Zebua; Nilsya Febrika Zebua; Sumardi; Suprianto; Putri Addina
Jurnal Indah Sains dan Klinis Vol 5 No 1 (2024): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v5i1.03

Abstract

Background: Kolang-Kaling (Arenga pinnata Merr.) belongs to the Arecaceae family as a source of natural polysaccharides in the form of galactomannan which is usually used as an additional ingredient. Objective: The study was aimed at determining whether galactose-mannose from Kolang-Kaling (GKK) could be separated using chromatography and its levels using the iodometry method. Method: Extraction of galactomannan using distilled water as a solvent. Purification by Paper Chromatography using WEB [Water: Ethanol: Butanol] mobile phase; WAB [Water: Acetate: Butanol]; CH3COOH 10.0% and 50.0%; CA 10.0% and 20.0%. Purification by TLC uses a variation of the EA: H mobile phase. Results: The GKK extraction yield was 18,5 g (3.7%). The levels before and after inversion were 85.53% and 90.23% with a galactose-mannose standard of 94.52%. Conclusion: Galactomannan can be obtained from Kolang-Kaling extraction and its levels are determined using the iodometry method
Analisis Vitamin C Daging dan Kulit Buah Semangka Merah dan Kuning (Citrullus vulgaaris Schard) dengan Spektrofotometri UV Lidiya Sasmaita Sihotang; Suprianto; Samran; Debi Meilani
Jurnal Indah Sains dan Klinis Vol 5 No 2 (2024): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v5i2.06

Abstract

Latar Belakang: Iklim tropis negara Indonesia karena terletak di daerah khatulistiwa yang memberi peluang berbagai tanaman tumbuh dengan subur, termasuk buah-buahan. Umumnya, vitamin C merupakan salah satu kandungan yang terdapat pada buah-buahan, yang berperan sebagai antioksidan. Sekian banyaknya buah-buahan, slah satunya buah semangka (Citrullus vulgaris Schard). Buah semangka juga dimanfaatkan untuk menurunkan tekanan darah bagi penderita hipertensi, karena kandungan air dan kaliumnya yang tinggi sehingga mampu menstabilisasikan tekanan darah. Tujuan: Tujuannya untuk mendeteksi keberadaan dan kuantitas vitamin C pada daging dan kulit buah semangka merah dan kuning. Metode: Metode yang digunakan meliputi uji kualitas dan kuantitas masing-masing dengan pereaksi warna dan spektrofotometri UV. Hasil: Penelitian memberi informasi pada daging dan kulit buah semangka terdapat vitamin C dengan tanda ada perubahan warna maupun pengendapan kuning-merah bata dan coklat. Vitamin C dari daging dan kulit buah semangka merah dan kuning masing-masing adalah 50,688; 42.482; 34.764; dan 42,152 gr/L. Kesimpulan: Daging maupun kulit buah semangka merah dan kuning ditemukan vitamin C.
OPTIMASI FORMULA MATRIKS KITOSAN DENGAN METILSELULOSA PADA PELEPASAN TERKENDALI SEDIAAN GRANUL TEOFILIN Suprianto Suprianto
Jurnal Ilmiah Manuntung Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v1i2.22

Abstract

The in vitro study was carried out on the release of active ingradient theophylline from granules prepared by moist granulation method. The granule matrix was prepared from the mixture of chitosan isolated from SwaIIo shrimp (Metapenaeus monoceros) (in accordance with the Protan Laboratories, Inc standard requirement) and methylceliuiose 1500 cps. The granules were filled into 850 mg capsules containing 200 mg theophylline. The maximum weight of chitosan and methylcellulose for each capsule was determined by factorial design 22.The result showed that, when the amount of chitosan was kept constant, an increase in the amount of methylcellulose will increase the release rate of theophylline from granules. The optimum weight of chitosan and methyIceIIuIose are 609.24 mg and 20.00 mg, respectively for one capsule.
ANALISIS KINETIKA PELEPASAN TEOFILIN DARI GRANUL MATRIKS KITOSAN Suprianto Suprianto
Jurnal Ilmiah Manuntung Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v2i1.50

Abstract

Moment the drug dosage form development, it is important to study the drug release or dissolution that is recognized as an element in drug development. Mathematical models could help optimize the design of drugs to produce models of drug release information. Analysis of quantitative values obtained when depicting dissolution drug release profiles more easily when the mathematical concepts used to describe the drug release kinetics model. Model release of drugs known include zero order, first order, Higuchi models, models Hixon Crowell and Peppas Korsmeyer models. The purpose of this review apply mathematical concepts to study the phenomenon of drug release theophylline granules matrix made from chitosan
Co-Authors Abdul Latif Abdul Rahim Adek Chan Afriadi Afriadi Agustine, Nita Claudia Ahmad Hafizullah Ritonga Akhsal, Muhammad Alam Suhada Alam Suhada Alamsyah, Sayyidul Aulia Alfani, Andri Alizha Aisyah Ananda Sri Devy Ancel Mus Silaban Andilala Andraini, Galuh Anita Anita Anjur Falden Lingga Annas Reza Annas Reza Ardani Ardani Ardina Ardina Ardina Pakpahan Arie Wardhono Arinri Misnangin Sritala Ramadani Arinri Misnangin Sritala Ramadani As-Sidqi, Miftakhul Hidayatullah Atika, Nur Ayomi, Siti Azmi, Muhammad Farhan Bambang Purnomo Yanuarso BENNI ISKANDAR Bunga Nur Julianingtyas, Bunga Nur Cahyono, Bowo Eko Chan, Adek Cinde Ririh Windayu Cut Fatimah Cut Fatimah Cyndi Veronica DARMANSYAH . Darmawan, Sukma Adi De Lux Putra, Effendy Debi Meilani Debi Melani Derlina . Devi Purnama Sari Dewi Kartika Dewi Sartika Munthe Dian Zulkarnain Lubis Dikari Harita Dwi Fita Heriyawati Dwi Setio Purnomo Effendy De Lux Putra Eko Sutrisno, Eko Elliza Rizki Wandani Elvy Oktima Elvy Oktima Endang Subekti Endang Subekti Enny Fitriani Fadilah, Ilham risqi Fahad Fahad Fartimah, Siti Fauzi, Rafli Febriady, Andy Ferdiansah, Muhammad Vicky Fesri Damai Riang Laia Fesri Damai Riang Laia Fina Dheny Lantika Firnanda, Basyid Fitri Mayang Sari Fitriani Nasution Fitriani, Enny Gatot Kusjono Haerul Pathoni, Haerul Hakim, Syamsul Hamdani Hamdani Hanafi, Mohammad Iqbal Handrito , Radityo Putro Hapsari Peni Harianto, Bambang Bagus Harman, Anita Hasrat Masa Harefa Hendri Faisal Herliana Herlina H Herlina Herlina Hermansyah . Hetty Wahyuni Hunowu, Adam Husnul Khatimah I Gusti Putu Asto Buditjahjanto I Kadek Suardika I Made Budiarsa I.G.P Asto Buditjahjanto Ibana, Lukluk Ibana Ihsanul Hafiz Indra Ginting Indrasari, Hairuni Jainuddin, Jainuddin Jakub Tarigan Jakub Tarigan Jamaluddin Jelly Syahfitri Johannes Johannes Joko Wibowo Kantari, Losa Ade Kartika, Unit Three Kurniawansyah Kurniawansyah Kusjono, Gatot Kusmini Suprihatin Kusumastuti, Melati Yulia Leny, Leny Lestari, Wita Lidiya Sasmaita Sihotang Lili Nurmaliza Lilik Anifah Loetfia Dwi Rahariyani Lukman Hakim Lukmanul Hakim Luly Triningsih Mairani, Fridelly Mandike Ginting Mandike Ginting MARIFANI FITRI ARISA Maulana Muhammad Jogo Samudro Maya Annisa Lubis Maya Sartika Maya Sartika Melati Yulia Kusumastuti Melati Yulia Kusumastuti Merita Indrawati, Elsanda Mia Maelani Moch. Bahrudin Mohammad Hidayaturrahman Mubarak, Abdulah Mudakir, Kharis Muh. Hasbi Muhammad Deddy Harfiansyah Muhammad Deddy Harfiansyah Muhammad Gunawan Muhammad Gunawan MUHAMMAD HASBI Muiz, Ahmad Habibul Mulyadi, Syifaul Aini Musyarrofah, Wilda Muzakki, Naufal Nasir Nasir Nasrullah, Muh. Nasution, Lely Fitri Handayani Nicko, Abed Nilsya Febrika Zebua, Nilsya Febrika Ningsih, Risma Nining Sudiyarti Novia Susanti Novitasari, Intan Sekar Nur Aini, Intan Nur Aisyah Pitri Nur Asni Arti Nur Asni Arti Nurasyah Nurasyah Nurhayati Nurhayati Nurlela Petra Saragih Nurul Ratnawati, Nurul Nur’Adina Nur’Adina Nur’Adina Pangga, Dwi Panjaitan, John David Willy Peri Aisyah Zubaidi Permata, Yade Metri Pranata, Chandra Prihanto, Yusep Putri Addina Rachel Anastasia R Hutabarat Rahman, Khalifatur Ramli Ramli Rehanun Resaldi A, Devano Ilham Riesha, Riezky Army Rifa'i, Anggi Muhammad Rifqi Firmansyah, Rifqi Rillia Aisyah Haris Rini Agustina Riska Riska Risma Niswaty Risma Yeni Roos Nana Sucihati Rosary, A. Osfira Rotua Sumihar Sitorus Ruseni Ruth Mayana Rumanti Ruth Mayana Rumanti S, Ahmad Suryadi Sahrita Sahrita Said , Amal Samran, Samran Saputra, Zanuar Faudino Saragih, Safitri Sasilatha, T. Saswan, Munadi Agri Sefryantonius Lase Septian, Afan Maulana Sertin Prilda Sari Sandoro Sertin Prilda Sari Sandoro Setiawan, Bhayu Aji Shofian Syarifuddin Sindy Andriani Siregar, Dwiki Rifhardi Siregar, Riwandi Siregar, Suci Rahmadani Siti Fatimah Hanum Siti Nurbaya Siti Nurbaya Siti Rahmi, Siti Sri Handayani Sri Rahayu SRI RAHAYU Sudirman Sugiantiningsih, Anak Agung Putu Suhendra Tawarnate Sumardi Sumardi Sumardi . Sutji Rochaminah Syamruddin Syamruddin Syamsul, Darwin Syukur, Hendrodinus Widono Tambubolon, Regina Elianda Ubaid, Ahmad Hasan Ucok Hasian Refeiater Umniyah, Inas Alfiyatul Unit Three Kartini Vivi Eulis Diana Vivi Eulis Diana Wilda Rizwani Winarsih, Rini Winarsih Winata, Hanafis Sastra Yudairawan, Listyo Zai, Arifin Putra Zebua, Nilsya Febrika Zebua Zuhrie, Muhamad Syariffuddien Zulkia, Andipta Ahmad