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Dampak Pewarna Ekstrak Etanol Buah Naga Merah (Hylicerius polyhizus) terhadap Lip Balm Minyak Bunga Kenanga (Cananga oil) Meilani, Debi; Suprianto, Suprianto; Samran, Samran
Jurnal Indah Sains dan Klinis Vol 5 No 3 (2024): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v5i3.02

Abstract

Background: Red dragon fruit holds promise as a natural dye alternative due to its anthocyanin content. Objective: This study aimed to evaluate the potential of ethanol extract from red dragon fruit as a dye in Lip Balm formulations and investigate how varying the concentration of this extract affects the formula. Method: The study involved extracting the dye from red dragon fruit and incorporating it into a Lip Balm preparation using natural fruit-based dyes. Results: The findings indicated that the red dragon fruit extract yielded favorable results after undergoing various tests, including organoleptic evaluation, homogeneity, melting point, irritation, and user preference. Conclusion: The extract of red dragon fruit can be utilized as a dye in Lip Balm formulations. The resulting colors range from pink to dark red, with higher concentrations of the extract producing more intense colors in the final Lip Balm product containing ylang-ylang flower oil (Cananga oil)
Analisis Parasetamol Tablet dengan Metode Fourier Transform Infra Red (FTIR) Saragih, Safitri; Suprianto, Suprianto; Samran, Samran
Jurnal Indah Sains dan Klinis Vol 5 No 3 (2024): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v5i3.05

Abstract

Background: Paracetamol, a widely used analgesic and antipyretic medication, is commonly prescribed in government healthcare facilities. The FTIR method provides rapid measurements by analyzing spectral graphs that reveal the functional groups within the tested compounds. According to the Indonesian Pharmacopoeia, VI Edition 2020, paracetamol content in tablet formulations must range between 90.0% and 110.0%. Objective: This study aimed to evaluate the paracetamol content in tablet preparations and assess their compliance with the 2020 Indonesian Pharmacopoeia standards and the packaging labels. Method: The research was conducted experimentally using FTIR spectroscopy. A solvent mixture of ethanol and distilled water (1:1) was employed, with analyses performed over the wavelength range of 4000–400 cm⁻¹. Results: The paracetamol content was found to be highest in tablet B (100.33 ± 1.003%), followed by tablet A (100.29 ± 1.002%), tablet D (100.24 ± 1.002%), and tablet E (100.14 ± 1.001%), with the lowest levels observed in tablet C (99.69 ± 0.996%). Method validation indicated an RSD value of 0.056%, confirming that the procedure was accurate and reliable. Conclusion: The findings demonstrate that the FTIR method is suitable for the quantitative analysis of paracetamol in tablet formulations. Moreover, the results meet the standards outlined in the 2020 VI Edition of the Indonesian Pharmacopoeia.
Penerapan Sanitasi dan Higienis dalam Pembuatan Jamu Gendong di Kota Tebing Tinggi Suprianto, Suprianto; De Lux Putra, Effendy; Nurbaya, Siti; Samran, Samran; Sumardi, Sumardi; Nasution, Derlina; Lestari, Wita
Mejuajua: Jurnal Pengabdian pada Masyarakat Vol. 4 No. 3 (2025): April 2025
Publisher : Yayasan Penelitian dan Inovasi Sumatera (YPIS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/mejuajuajabdimas.v4i3.220

Abstract

Jamu Gendong is a traditional drink that has the potential to be contaminated with worms, parasites, bacteria, fungi, viruses and rickettsia. Sources of contaminants include materials, equipment, facilities, personnel, animals and production environments, so their efficacy is questionable. The activity was carried out in the form of providing information on the implementation of sanitation and hygienic production to 38 Jamu Gendong traders in Tebing Tinggi City, Deli Serdang, North Sumatra. The material was delivered using illustrated power point media to facilitate the delivery of increased understanding of sanitation and hygiene, including objectives, benefits, programs, fixed procedures, disinfectant and washing materials as well as documentation in accordance with RI POM Regulation Number 31, 2022. Activities were carried out on April 29, 2024 and received positive responses from all participants. Activities are expected to be sustainable so that the Jamu Gendong produced is of higher quality.
Korelasi Konsumsi Sidaguri dengan Kadar Asan Urat Darah Suprianto, Suprianto; Adek Chan; Joko Wibowo; Samran; Sumardi; Debi Meilani
Jurnal Indah Sains dan Klinis Vol 6 No 1 (2025): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v6i1.02

Abstract

Background: Hyperuricemia as an indicator of increased blood uric acid. The prevalence rate in Indonesia is not recorded with certainty. However, the prevalence of gout reached 655,745 people out of 238,452,952 people in Indonesia, ranking first in Southeast Asia. Sidaguri flavonoids have inhibitory power against Xanthine Oxidase so that they can reduce uric acid. Objective: The study was aimed at detecting the effect and correlation of Sidaguri capsule consumption (Sida rhombifolia L) on reducing uric acid in patients. Method: The study was conducted Pretest and Posttest on 22 patients with hyperuricemia with the Easy Touch GCU Instrument. Results: The results showed that the average uric acid level before the intervention was 8.37 mg/dL and after the intervention was 6.57 mg/dL. Conclusion: Sidaguri capsules have an effect on reducing uric acid levels in patients
Validasi Metode Penetapan Kadar Monosodium Glutamat pada Mie Ayam dengan Spektrofotometri UV–Vis Setelah Derivatisasi Ninhidrin Suprianto; Effendy De Lux Putra; Samran; Siti Nurbaya; Cyndi Veronica; Sumardi; Debi Meilani
Jurnal Indah Sains dan Klinis Vol 6 No 2 (2025): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v6i2.05

Abstract

Pendahuluan: Mie Ayam merupakan aneka olahan mie yang dijajakan, disajikan dan dinikmati dengan cita rasa yang sangat lezat; dijajakan dari mulai gerobak jalan, di pinggir jalan maupun tempat lesehan. Mie Ayam diolah dengan penambahan berbagai bahan tambahan pangan agar diperoleh makanan yang dapat membangkitkan selera konsumen. Mie Ayam yang disajikan harus diproses dengan benar sehingga konsumen aman setelah konsumsi makanan tersebut. Monosodium glutamate (MSG) merupakan bahan tambahan pangan yang biasa ditambahkan pada makanan untuk meningkatkan cita rasa makanan, terutama rasa lezat makanan. MSG ditambahkan pada produk pangan tidak lebih dari 10g/kg Bahan Pangan agar konsumen terjamin kesehatannya. MSG dapat diderivatisasi dengan ninhidrin sehingga penetapan kadar dapat dilakukan dengan spektrofotometri visibel. Tujuan: Menentukan kadar MSG pada Mie Ayam secara spektrofotometri UV. Metode: Penetapan kadar MSG dilakukan secara spektrofotometri UV setelah dilakukan derivatisasi dengan Ninhidrin. Hasil: Kadar MSG pada Mie diperoleh pada rentang 1,9441- 2,4726 g/kg bahan pangan dan di bawah batas maksimum 10 g /kg bahan pangan menurut EPSA. Kesimpulan: Kadar MSG pada Mie Ayam pada rentang tertentu dan masih di bawah batas maksimum.
Controlled release kinetics of furosemide from chitosan matrix tablets with hydroxypropyl methylcellulose phthalate coated Samran, Samran; Suprianto, Suprianto; Sumardi, Sumardi; Ritonga, Ahmad Hafizullah; Kusumastuti, Melati Yulia
Pharmaciana Vol. 14 No. 2 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i2.28097

Abstract

Sustained-release dosage forms were critical in drug delivery, ensuring controlled and prolonged release for optimal therapeutic outcomes. Chitosan (CH) has become pivotal in sustained-release tablet formulation due to its biocompatibility and mucoadhesive properties. This study aims to explore the release kinetics of furosemide (FS) from CH matrix tablets in a concurrent medium. The formulation involves a core tablet and coated tablet, with CH matrix as a binder and Hydroxypropyl Methyl Cellulose Phthalate (HPMCP) as a film-coated for the core tablet, and both are made using the wet granulation method. Assessment parameters include tablet hardness, disintegration, and FS release profiles across various media, analyzed using spectrophotometric methods to comprehend drug release kinetics with multiple models such as zero-order, first-order, Higuchi, and Korsmeyer-Peppas employed. In the press-coated tablet comprising core tablet CH as matrix uncoated with 20 mg CH per tablet core, a zero-order release pattern emerged in the pH 1.2 medium within 0-2 h, which displayed first-order release kinetics within 2-6 h and 6-16 h in concurrent media of pH 5.8 and 7.4. Notably, a zero-order release pattern emerged in the pH 1.2 medium within 0-2 h. Press-coated tablets incorporating CH matrix with HPCMP coated (CH-HPCMP), also containing 20 mg CH per tablet, exhibited diverse drug release kinetics. These tablets showed Korsmeyer-Peppas, zero-order, and first-order kinetics in pH 1.2, 5.8, and 7.4, respectively. The study suggests that a Press-coated tablet incorporating CH-HPMCP is suitable as the candidate for sustained-release formulations. The observed versatility in release kinetics across varying pH environments underscores the potential adaptability of these formulations in addressing diverse therapeutic needs.
FORMULASI SHEET MASK EKSTRAK ETANOL KULIT PISANG AMBON (Musa paradisiaca L.) SEBAGAI MOISTURIZING Chan, Adek; Afriadi, Afriadi; Winata, Hanafis Sastra; Suprianto, Suprianto; Sahrita, Sahrita
Jurnal Ilmiah Manuntung Vol 7 No 1 (2021): Jurnal Ilmiah Manuntung
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v7i1.424

Abstract

Ambon banana peel contains flavonoid chemical compounds that can moisturize facial skin. Flavonoids are powerful antioxidants. A sheet mask formulation of Ambon banana peel extract that can be used more practically and is able to moisturize facial skin. This study aims to formulate a mask sheet preparation containing ethanol extract of Ambon banana peel as well as better skin maintenance for four weeks of treatment and measuring the moisture content of the skin. The research method used is an experimental method, namely the extract is obtained using the maceration method, then formulated into a sheet mask preparation, consisting of glycerin, butylene glycol, sodium polyacrylate, nipagin, PEG-40 Hydrogenated Castrol oil, aquadest, perfume, and banana peel ethanol extract. Ambon with concentrations of F1 (1%), F2 (3%), F3 (5%), F4 (7%), F5 (9%), respectively. As blank (F0) sheet mask preparation without the addition of extract. The preparation is evaluated including homogeneity test, pH test, stability test, irritation test, Moisture effectiveness test using Moisture Checker and preference test. The treatment is carried out for 4 weeks by applying the mask twice a week. Data obtained from the analysis using the SPSS program. The results showed that the ethanol extract of Ambon banana peel can be formulated in a homogeneous sheet mask preparation, does not change color and remains stable in 4 weeks of storage with a pH of 4.6 - 6.6. Conclusion The ethanol extract of Ambon banana peel can be formulated into sheet masks with concentrations of 1%, 3%, 5%, 7% and 9% with a positive control ratio.
Correlation of Education Level with Mother's Knowledge About the Nutritional Status of Stunted Toddlers Sitorus, Rotua Sumihar; Suprianto, Suprianto
Jurnal Keperawatan Priority Vol. 7 No. 1 (2024)
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jukep.v7i1.4472

Abstract

Chronic malnutrition due to prolonged malnutrition resulting in stunted growth and development. Educated and knowledgeable mothers have a big influence on the pattern of regulating balanced food needs for the growth and development of toddlers. The research was directed at determining the correlation between educated and knowledgeable mothers on the nutritional status of stunted toddlers in the Namorambe Community Health Center work area. Quantitative descriptive research was conducted cross-sectionally. The population was 32 mothers who had stunted toddlers (0-59 months) and the total was the sample. Univariate and bivariate analyzes were carried out to describe the frequency distribution of respondents' characteristics and determine the correlation between educated and knowledgeable mothers regarding the nutritional status of stunted toddlers. The results showed that mothers ranged from 20-30 years old and had upper secondary education as many as 25 (78.1%) and 21 (65.6%); toddler age 37-60 months, male gender, stunted toddler, and poor maternal knowledge were 16 (50%), 17 (53.1%), 22 (68.8%) and 23 (71.9%); and as many as 21 (65.6%) and 12 (37.5%) respondents had high school education and poor knowledge; as well as the Chi-square analysis results of p-value = 0.038, respectively. In the research, there was a correlation between educated and knowledgeable mothers on the nutritional status of stunted toddlers in the Namorambe Community Health Center work area.
Factors That Increase The Risk of A Mother Giving Birth to A Stunting Toddler Sitorus, Rotua Sumihar; Suprianto, Suprianto; Herlina, Herlina
Jurnal Keperawatan Priority Vol. 7 No. 2 (2024)
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jukep.v7i2.5302

Abstract

Stunting is a condition where linear growth is disturbed so that the body height is not normal, also known as being short or dwarf in comparison to the standard age. This matter is caused by nutrition and health in the poor pre- and post-natal period. An educated and knowledgeable mother has a significant role in overcoming, managing, and organizing family resources to meet nutritional needs. The study was directed at analyzing factors that increase the risk of mothers giving birth to stunted toddlers in work areas at the Public Health Center Namorambe. The study uses a descriptive-analytical approach using a cross-sectional model, where data collection is conducted in a single instance.Thirty mothers were studied as study subjects with toddlers ages 0–60 months with stunting conditions and living in the work area of the Public Health Center Namorambe. The study results show that the possibility of mothers giving birth to stunted toddlers is affected by their knowledge, attitudes, and actions.
Sports Massage Training and Injury Repositioning Students of Yapis Timika Vocational School Herwin, Herwin; Trisakti, Jhon Citro; Nurwirhanuddin, Nurwirhanuddin; Suprianto, Suprianto; Letisia, Maria; Siga, Adolfus Siktus; Renyaan, Anastasya; Umafagur, Dea Andela
Abdi Masyarakat Vol 7, No 2 (2025): Abdi Masyarakat
Publisher : Lembaga Penelitian dan Pendidikan (LPP) Mandala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58258/abdi.v7i2.8932

Abstract

Sports massage is a form of massage therapy designed to accelerate recovery and improve the performance of athletes and non-athletes who engage in various physical activities. Sports massage can be given to children, adolescents, and adults, including workers, students, and college students. Sports massage is not only for athletes but can also be given to students to prevent and hinder injuries during the learning process at school. It can also provide first aid if a fellow student experiences an injury, whether during extracurricular or extracurricular activities.This community service program aims to provide education about sports massage and injury repositioning to students and teachers involved in extracurricular activities, thereby fostering independence in helping fellow students in the event of injuries and enabling teachers to provide professional services to their students. Furthermore, this PKM activity, as an implementation of the sports massage course in the community, involves students who have completed the theory/practice of sports massage courses.The data collection technique used in this Community Service (PKM) was an evaluation method, conducted by administering a participant satisfaction questionnaire after the training was completed. The questionnaire was administered online using the Google Forms platform to participants in the sports massage and injury repositioning training. In addition to data on student and teacher/extracurricular instructor satisfaction indicators, physical evidence also included documentation from before, during, and after the training.The data were analyzed using descriptive methods. Based on the results of the evaluation, it shows that from the training activities that have been given to students of SMK Yapis Timika from a total of 18 students, it was found that 82.6% of students strongly agree, students agree 14.7%, students quite agree 2.7%. Meanwhile, the results of the evaluation that followed the training showed that from the training activities that have been given to teachers/extracurricular instructors of SMK Yapis Timika from the number of teachers/extracurricular instructors who participated in this activity 1 person, it was found that 70% of teachers/extracurricular instructors strongly agree, teachers/extracurricular instructors agree 25%, teachers/extracurricular instructors quite agree 5%.
Co-Authors Abdul Rahim Adek Chan Afriadi Afriadi Agustang, Andi Tenri Pada Ahmad Hafizullah Ritonga Ahmad Suryadi, Ahmad Akmal, Muh. Ikramullah Alam Suhada Alam Suhada Alizha Aisyah Ananda Sri Devy Ancel Mus Silaban Andilala Andraini, Galuh Anita Anita Anjur Falden Lingga Annas Reza Annas Reza Ardina Ardina Ardina Pakpahan Ariantini, Nisa Arinri Misnangin Sritala Ramadani Arinri Misnangin Sritala Ramadani Arti, Widi Atika, Nur BENNI ISKANDAR Chan, Adek Cinde Ririh Windayu Cut Fatimah Cut Fatimah Cyndi Veronica De Lux Putra, Effendy Debi Meilani Debi Melani Derlina . Devi Purnama Sari Dewi Kartika Dewi Sartika Munthe Diah Padmi, Ni Made Dian Zulkarnain Lubis Dikari Harita Dwi Setio Purnomo Effendy De Lux Putra Efriwanda Pratama, Calvine Elvy Oktima Elvy Oktima Endang Subekti Endang Subekti Enny Fitriani Febriady, Andy Fesri Damai Riang Laia Fesri Damai Riang Laia Fina Dheny Lantika Fitri Mayang Sari Fitriani Nasution Fitriani, Enny G Bula, Yuyun Haryani, Meri Hasrat Masa Harefa Hendri Faisal Herliana Herlina H Herlina Herlina Hermansyah . Herwin Herwin, Herwin Hetty Wahyuni Hindarto Idrus, Muh. Ikhsan Ihsanul Hafiz Ikramullah, Muh Indra Ginting Iskandar, Didik Jakub Tarigan Jakub Tarigan Jelly Syahfitri Johannes Johannes Joko Wibowo Khusna Arif Rakhman, Khusna Arif Kurniawansyah, Kurniawansyah Kusumastuti, Melati Yulia Leny, Leny Lestari, Wita Letisia, Maria Lidiya Sasmaita Sihotang Lili Nurmaliza Lukmanul Hakim Luly Triningsih Luthfi Siraj, Muhammad Maelani, Mia Mairani, Fridelly Mandike Ginting Mandike Ginting Maya Annisa Lubis Maya Sartika Maya Sartika Melati Yulia Kusumastuti Melati Yulia Kusumastuti Mochamad Alfan Rosid Muhammad Deddy Harfiansyah Muhammad Deddy Harfiansyah Muhammad Gunawan Muhammad Gunawan Muhammad Luthfi Muhammad Rusdi Nasution, Lely Fitri Handayani Nilsya Febrika Zebua, Nilsya Febrika Ningsih, Chairunnisah Putri Ayu Nur Aisyah Pitri Nur Asni Arti Nur Asni Arti Nurasyah Nurasyah Nurfatimah Sugrah Nurkhoiroh Nurkhoiroh Nurlela Petra Saragih Nurul Fadilah, Nurul Nurwirhanuddin, Nurwirhanuddin Nur’Adina Nur’Adina Nur’Adina Okky Zubairi Abdillah Peri Aisyah Zubaidi Permata, Yade Metri Pinem, Mhd Daud Pradana, Andre Aditya Pranata, Chandra Priyono, Alfanda Wahyu Oktavia Putri Addina Rachel Anastasia R Hutabarat Rahmania, Fitri Ramadhan, Mochammad Hisyam Syah Renyaan, Anastasya Risma Yeni Rotua Sumihar Sitorus Ruseni Ruth Mayana Rumanti Ruth Mayana Rumanti safri Irawan Sahrina, Alfi Sahrita, Sahrita Samran, Samran Saprini Hamdiani Saputra, Sepriadi Saragih, Safitri Sasmayunita Sefryantonius Lase Sertin Prilda Sari Sandoro Sertin Prilda Sari Sandoro Setyadi, Arrohman Shofian Syarifuddin Siga, Adolfus Siktus Sindy Andriani Siregar, Riwandi Siregar, Suci Rahmadani Siti Fatimah Hanum Siti Nurbaya Siti Nurbaya Siti Rahmi, Siti Sovayunanto, Riski Sri Handayani SRI RAHAYU Sri Rahayu Stephanie Bija Sucihati, Roos Nana Sudiyarti, Nining Suhendra Tawarnate Suherman Sumardi Sumardi Sumardi . Sundari Suryadi S, Ahmad Syamsul, Darwin Syarifuddin Syarifuddin Tambubolon, Regina Elianda Trisakti, Jhon Citro Umafagur, Dea Andela UMAR ISKANDAR, UMAR Vivi Eulis Diana Vivi Eulis Diana Wahab, Iis Hamsir Ayub Wandani, Elliza Rizki Wilda Rizwani Winata, Hanafis Sastra Y, Hasyrif S Yani, Achmad Yusri Sapsuha Zai, Arifin Putra Zebua, Nilsya Febrika Zebua