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All Journal JURNAL KIMIA SAINS DAN APLIKASI Pharmaciana: Jurnal Kefarmasian Journal of Islamic Pharmacy AKSIOLOGIYA : Jurnal Pengabdian Kepada Masyarakat JPM (Jurnal Pemberdayaan Masyarakat) Jurnal Ilmiah Manuntung JURNAL FARMASIMED (JFM) Jurnal Dunia Farmasi Jurnal Keperawatan Priority JURNAL PENELITIAN PERAWAT PROFESIONAL Abdi Masyarakat Jurnal Indah Sains dan Klinis Mejuajua Jurnal Ilmiah MADIYA: Masyarakat Mandiri Berkarya Indonesian Journal of Education Methods Development JURNAL KIMIA SAINTEK DAN PENDIDIKAN Jurnal Pengmas Kestra (JPK) Jurnal Muara Olahraga Jurnal Pengabdian Inovasi Masyarakat Indonesia Jurnal Informatika Polinema (JIP) Jurnal Indah Sains dan Klinis Jurnal Medika: Medika Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Edutik : Jurnal Pendidikan Teknologi Informasi dan Komunikasi Journal of Innovation and Sustainable Services
Suprianto Suprianto
Institut Kesehatan Medistra Lubuk Pakam
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Evaluasi Stabilisator Agar-Agar dan CMC Sediaan Sirup Markisa Berastagi Suprianto; Muhammad Gunawan; Melati Yulia Kusumastuti; Cut Fatimah; Debi Meilani
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/b1pzvs47

Abstract

Fruit syrup is made from a sugar solution, the taste and aroma are determined by the freshness of the fruit. Fruit commonly used in making syrup has an attractive color, aroma and distinctive taste. Passion fruit (Passiflora edulis Sims.) has a distinctive taste and aroma, so it is widely processed into syrup. This study was to evaluate CMC and Agar-Agar stabilizers in the passion fruit syrup formula. Evaluation includes color, appearance, texture, taste and aroma and hedonic tests are carried out. The results showed that there were significant differences in the color, appearance, texture, taste and aroma of passion fruit syrup. Stabilizers CMC and Agar-Agar make the color, texture and appearance of the syrup better and more attractive. The result of hedonic test for ideal syrup concentration is S3 with 4 g of Agar and 6 g of CMC. The higher the concentration of CMC and Agar, the greater the viscosity of the syrup. The concentration of CMC and Agar-agar in a mixture of fruit juices gave significantly different effects on color, texture, appearance, taste and aroma
Formulasi dan Evaluasi Sediaan Sabun Padat Antiseptik Ekstrak Etanol Daun Kunyit Suprianto; Sumardi; Debi Meilani; Sri Rahayu
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i1.44

Abstract

The plant of findings turmeric (Curcuma longa) are often used as a traditional medicinal. The part of the turmeric plant that is often used is the rhizome. In addition to turmeric rhizome, turmeric leaves are also used as a flavoring dish. Among the benefits of turmeric leaves is as an antimicrobial. Soap is a surfactant used for washing and cleaning. Antiseptics are inhibitors for the growth and development of microorganisms that live on the surface of the body. The study was to determine which ethanol extract of turmeric leaves could be formulated into antiseptic solid soap preparations. This study used an experimental method, turmeric leaves were extracted with 70% ethanol. The formula made are 2.5%, 5%, 7.5%. The quality of the soap preparation was carried out by organoleptic tests, acidity, high foam and irritation. The results test showed that the solid soap did not have the aroma of turmeric leaves, the pH of the soap was 9.9-10.5; foam height with a concentration of 7.5% which is 7.3 cm; and solid soap preparations ethanol extract of turmeric leaves did not cause irritation. The extract of turmeric leaves can be formulated into solid soap preparations. It is recommended to add perfume to the formulation of solid soap preparations of turmeric leaf extract as an antiseptic.
Evaluasi Konsentrasi Karboksimetilselulosa Alginat Formula Pasta Gigi Antiseptik Ekstrak Etanol Daun Seledri (Apium graveolens L.) Samran; Suprianto; Muhammad Gunawan; Melati Yulia Kusumastuti
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i1.45

Abstract

Maceration of Celery leaves using 96% ethanol solvent was used to make the extract. Toothpaste is formulated with carboxymethylcellulose and alginate binders. The active ingredient in the form of ethanol extract from Celery leaves has the potential for antibacterial. This study was to evaluate the concentration of carboxymethylcellulose alginate in the preparation of antiseptic toothpaste of ethanol extract from Celery leaves. Evaluation of production results consisted of organoleptic, homogeneity, spreadability, foam formation, acidity and viscosity. The higher the concentration of carboxymethylcellulose, the lower the foam and spreadability and the higher the viscosity, while the alginate concentration is the opposite. Carboxymethylcellulose alginate affects the evaluation parameters of antiseptic toothpaste preparations ethanol extract of Celery leaves
Analisis Biaya Efektif Terapi Diare Pasien Rawat Inap RS Putri Hijau Medan Muhammad Gunawan; Suprianto; Melati Yulia Kusumastuti; Sumardi; Debi Meilani
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i1.46

Abstract

Diarrhea is characterized by the excretion of liquid stools with a frequency of three or more times a day, due to gastrointestinal infections due to food and water contaminated with microorganisms, or directly from humans due to poor sanitation. This study was to determine the characteristics of diarrhea patients, treatment and cost-effectiveness of treatment at Putri Hijau Hospital, Medan. The non-experimental research is descriptive and retrospective in nature of financial patient medical records from July to December 2018. Cost Effectiveness Analysis as a method of cost analysis. The characteristics of the patients obtained were 14 women (46.670%) and 16 men (53.33%). The effectiveness of New Diatabs (92.30%) and New Diatabs Metronidazole (94.11%). The cost of therapy with New Diatabs is Rp. 1,547,771/patient and New Diatabs Metronidazole is Rp. 1,562,590/patient. Average cost-effectiveness New Diatabs Rp. 190,345 and New Diatabs Metronidazole Rp. 183,060, so it is concluded that the cost-effective therapy is the use of the combination of New Diatabs Metronidazole compared to New Diatabs.
Uji Ekstrak Kulit Buah Mangga Arum Manis dalam Etanol pada Tumbuh Kembang Escherichia coli dan Salmonella typhi Mandike Ginting; Suprianto; Siti Fatimah Hanum; Debi Meilani; Maya Sartika
Jurnal Indah Sains dan Klinis Vol 3 No 2 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i2.56

Abstract

Antibacterial interferes with growth and development and even kills by interfering with microbial metabolism. The peel of Mangifera indica L.var. arum manis contains antibacterial flavonoids. Research for the detection of antibacterial activity of mango peel extract of arum manis varieties in ethanol on E. coli and S. typhi. The well diffusion method was used with concentrations of 20.0%, 30.0% and 40.0%; chloramphenicol as a positive control. The diameter of the inhibition zone as an indicator of E. coli activity was 12.83 mm; 12.93 mm; and 13.91 mm, against S. typhi 11.60 mm; 12.52 mm; and 13.40 mm at these concentrations, respectively. Ethanol extract of Mangifera indica L. var. arum manis has antibacterial activity of E. coli and S. typhi with strong inhibitory power, and without differences in concentration
Validasi Metode Spektrofotometri UV Penetapan Kadar Tablet Ranitidin HCl dalam HCl Sefryantonius Lase; Suprianto, Suprianto
Jurnal Indah Sains dan Klinis Vol 5 No 1 (2024): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v5i1.01

Abstract

Introduction: Ranitidine HCl tablets are widely available in the market. Ensuring the proper levels of active ingredients is crucial for ensuring the quality of medications. Objective: To find a reliable method for measuring the levels of Ranitidine HCl tablets in acidic solvents that meet validation standards, and to explore valid methods using ultraviolet spectrophotometry in acidic solvents. Methods: UV spectrophotometry with a UV detector at maximum wavelength was used. Two solvents were employed: 0.10 N HCl and 0.15 N HCl. Method validation included tests for linearity, accuracy, repeatability, precision, and selectivity. Results: The maximum wavelengths detected for each solvent were 225 nm and 226 nm, respectively. Validation results indicate excellent linearity, accuracy, and precision within the ranges of 0.9984 - 0.9998; 99.6% - 100.7%; 0.427% - 0.861%; 0.518% - 0.952%. The selectivity test yielded positive outcomes. The average Ranitidine HCl tablet levels were 98.2% for PT. Hexpharm Jaya and 98.4% for PT. Mutifa Medan, meeting the standards of the Indonesian Pharmacopoeia Edition VI. Conclusion: The method using a 0.10 N solvent for determining Ranitidine HCl tablet levels meets validation requirements and is suitable for practical application.
Pemeriksaan Cemaran Mikroba Susu Sapi Segar Daerah Limau Manis Tanjung Morawa Deli Serdang Muhammad Gunawan; Suprianto
Jurnal Indah Sains dan Klinis Vol 5 No 1 (2024): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v5i1.02

Abstract

Background: Milk serves as a crucial source of human nutrition, particularly for infants who rely on it before they can digest solid foods. The mammary glands of female mammals produce it and is typically characterized by its pure white appearance. Objective: This study aimed to assess the levels of mesophilic aerobic bacteria and yeast mould present in fresh cow's milk obtained from farms in Limau Manis Tanjung Morawa. Methods: The investigation into contamination levels employed the Total Plate Count (TPC) method for aerobic bacteria and the Yeast Mold Count (YMC) method, both of which are based on the guidelines outlined in the Indonesian National Standard (SNI) No. 3141.1 of 2011. Results: Findings revealed that the levels of aerobic mesophilic bacteria, as determined by the TPC method, met the stipulated requirements of SNI No. 3141.1 of 2011 across all five farms surveyed. However, the research utilizing the YMC method indicated that the yeast mould counts in the milk from all five farms did not meet the established criteria. Conclusion: The analysis of microbial contamination using the TPC and YMC methods demonstrated compliance and non-compliance, respectively, with the standards outlined in SNI No. 3141.1 of 2011.
Analisis Kualitatif BKO Deksametason pada Jamu Peningkat Selera Makan dengan Spektrofotometer FTIR Jelly Syahfitri; Suprianto
Jurnal Indah Sains dan Klinis Vol 5 No 2 (2024): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v5i2.01

Abstract

Background: Jamu, a traditional health service deeply ingrained in Indonesian culture, has been utilized for generations. Among the herbal remedies sought after by the public, herbal medicine aimed at enhancing appetite stands out. Unfortunately, the robust demand for these products is often exploited by manufacturers who incorporate pharmaceutical additives. Dexamethasone, a synthetic glucocorticoid renowned for its anti-inflammatory and immunosuppressant attributes, is frequently amalgamated with herbs to stimulate appetite. Its inclusion is prompted by its known side effect of moon face and its potential to enhance appetite with prolonged use. Objective: This research endeavors to ascertain the presence of dexamethasone in the herbal appetite stimulants available in the market within Lubuk Pakam District, Deli Serdang, North Sumatra. Method: Qualitative analysis of dexamethasone was conducted utilizing Fourier Transform Infra Red (FTIR) spectrophotometry. Results: The investigation revealed that several samples of appetite-enhancing herbal medicine suspected to contain dexamethasone indeed exhibited spectra akin to the standard comparison of dexamethasone. Conclusion: Among the ten samples of herbal appetite stimulants scrutinized, eight were found to contain dexamethasone, as evidenced by the congruence of their spectra and functional groups with the comparison standard for dexamethasone.
Uji Kemurnian Ekstrak Galaktomanan Biji Durian (Durio zibethinus L.) dengan Metode Luff Schoorl Zebua, Nilsya Febrika; Sumardi; Suprianto; Alizha Aisyah
Jurnal Indah Sains dan Klinis Vol 3 No 3 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i3.01

Abstract

Introduction: Galactomannan is found in the endosperm of seeds in the Fabaceae family, for example durian seeds (Durio zibethinus L). Galactomannan is a natural polysaccharide as an additional ingredient. Objective: The research aims to determine the Galactomannan content in Durian seeds isolated by chromatography and to determine the Galactomannan content in Durian seeds using the Luff Schoorl method. Methods: The research was carried out by extracting galactomannan from Durian seeds using distilled water by heating them for 5 minutes. Purification was carried out using paper chromatography with various variations of mobile phases, namely BEW (Butanol: Ethanol: Water), BAW (Butanol: Acetic acid: Water), Glacial acetic acid 10%, Glacial acetic acid 50%, HCl 10%, HCl 20% and Thin layer chromatography with the mobile phase n-Hexane: Ethylacetate at varying ratios of 3:7 and 7:3. Purity testing is carried out using the Luff Scroorl method. Results: Extraction of 500 g of durian seeds produces 1,8% Galactomannan. The levels before and after inversion using the Luff Schoorl method were respectively 8.0131 and 7.0679 mg/mg. Conclusion: Galactomannan can be obtained from extracting durian seeds and its inverse using the Luff Scroorl method.
Analisis Kadar Kalsium, Kalium, Besi Akibat Variasi Waktu Rendam Kacang Produksi Susu Almond secara Spektrofotometri Serapan Atom Yade Metri Permata; Suprianto; Ananda Sri Devy
Jurnal Indah Sains dan Klinis Vol 3 No 3 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i3.02

Abstract

Background: Calcium, potassium and iron can be obtained from milk, nuts, eggs, fish, fruit vegetables, green vegetables and products needed by the human body which play a role in maintaining body functions, including cells, tissues, organs and overall function. Objective: Research to determine the levels of these minerals in almond milk using atomic absorption spectrophotometry (AAS). Method: Almonds were soaked for 4, 8, and 12 hours respectively for almond milk 1, 2, and 3 (SA1, SA2, and SA3) and Almendrola packaged milk (SA4). Samples were wet digested with concentrated HNO3. Analysis of calcium, potassium and iron levels using AAS with an air-acetylene flame was 422.7; 766.5; and 248.3 nm for calcium, potassium and iron respectively. Validated methods include accuracy, precision, LOD and LOQ. Results: Results of determining the mineral content of almond milk (mg/100g) for calcium, potassium and iron respectively (2.6551 ± 0.0925; 5.5464 ± 0.3178; 5.8866 ± 0.03805; and 4.5842 ± 0.2590), (2.4096 ± 0.0551; 2.5150 ± 0.0115; 2.6551 ± 0.0557; and 2.5150 ± 0.0551), and (0.3202 ± 0.0282; 0.3307 ± 0.0048; 0.3344 ± 0.011; and 0.3183 ± 0.0045). Conclusion: Validation of the method meets the requirements, soaking impacts increasing mineral levels in Almond Milk, and there are significant differences in calcium, potassium and iron levels in the milk.
Co-Authors Abdul Rahim Adek Chan Afriadi Afriadi Agustang, Andi Tenri Pada Ahmad Hafizullah Ritonga Ahmad Suryadi, Ahmad Akmal, Muh. Ikramullah Alam Suhada Alam Suhada Alizha Aisyah Ananda Sri Devy Ancel Mus Silaban Andilala Andraini, Galuh Anita Anita Anjur Falden Lingga Annas Reza Annas Reza Ardina Ardina Ardina Pakpahan Ariantini, Nisa Arinri Misnangin Sritala Ramadani Arinri Misnangin Sritala Ramadani Arti, Widi Atika, Nur BENNI ISKANDAR Chan, Adek Cinde Ririh Windayu Cut Fatimah Cut Fatimah Cyndi Veronica De Lux Putra, Effendy Debi Meilani Debi Melani Derlina . Devi Purnama Sari Dewi Kartika Dewi Sartika Munthe Diah Padmi, Ni Made Dian Zulkarnain Lubis Dikari Harita Dwi Setio Purnomo Effendy De Lux Putra Efriwanda Pratama, Calvine Elvy Oktima Elvy Oktima Endang Subekti Endang Subekti Enny Fitriani Febriady, Andy Fesri Damai Riang Laia Fesri Damai Riang Laia Fina Dheny Lantika Fitri Mayang Sari Fitriani Nasution Fitriani, Enny G Bula, Yuyun Haryani, Meri Hasrat Masa Harefa Hendri Faisal Herliana Herlina H Herlina Herlina Hermansyah . Herwin Herwin, Herwin Hetty Wahyuni Hindarto Idrus, Muh. Ikhsan Ihsanul Hafiz Ikramullah, Muh Indra Ginting Iskandar, Didik Jakub Tarigan Jakub Tarigan Jelly Syahfitri Johannes Johannes Joko Wibowo Khusna Arif Rakhman, Khusna Arif Kurniawansyah, Kurniawansyah Kusumastuti, Melati Yulia Leny, Leny Lestari, Wita Letisia, Maria Lidiya Sasmaita Sihotang Lili Nurmaliza Lukmanul Hakim Luly Triningsih Luthfi Siraj, Muhammad Maelani, Mia Mairani, Fridelly Mandike Ginting Mandike Ginting Maya Annisa Lubis Maya Sartika Maya Sartika Melati Yulia Kusumastuti Melati Yulia Kusumastuti Mochamad Alfan Rosid Muhammad Deddy Harfiansyah Muhammad Deddy Harfiansyah Muhammad Gunawan Muhammad Gunawan Muhammad Luthfi Muhammad Rusdi Nasution, Lely Fitri Handayani Nilsya Febrika Zebua, Nilsya Febrika Ningsih, Chairunnisah Putri Ayu Nur Aisyah Pitri Nur Asni Arti Nur Asni Arti Nurasyah Nurasyah Nurfatimah Sugrah Nurkhoiroh Nurkhoiroh Nurlela Petra Saragih Nurul Fadilah, Nurul Nurwirhanuddin, Nurwirhanuddin Nur’Adina Nur’Adina Nur’Adina Okky Zubairi Abdillah Peri Aisyah Zubaidi Permata, Yade Metri Pinem, Mhd Daud Pradana, Andre Aditya Pranata, Chandra Priyono, Alfanda Wahyu Oktavia Putri Addina Rachel Anastasia R Hutabarat Rahmania, Fitri Ramadhan, Mochammad Hisyam Syah Renyaan, Anastasya Risma Yeni Rotua Sumihar Sitorus Ruseni Ruth Mayana Rumanti Ruth Mayana Rumanti safri Irawan Sahrina, Alfi Sahrita, Sahrita Samran, Samran Saprini Hamdiani Saputra, Sepriadi Saragih, Safitri Sasmayunita Sefryantonius Lase Sertin Prilda Sari Sandoro Sertin Prilda Sari Sandoro Setyadi, Arrohman Shofian Syarifuddin Siga, Adolfus Siktus Sindy Andriani Siregar, Riwandi Siregar, Suci Rahmadani Siti Fatimah Hanum Siti Nurbaya Siti Nurbaya Siti Rahmi, Siti Sovayunanto, Riski Sri Handayani Sri Rahayu SRI RAHAYU Stephanie Bija Sucihati, Roos Nana Sudiyarti, Nining Suhendra Tawarnate Suherman Sumardi Sumardi Sumardi . Sundari Suryadi S, Ahmad Syamsul, Darwin Syarifuddin Syarifuddin Tambubolon, Regina Elianda Trisakti, Jhon Citro Umafagur, Dea Andela UMAR ISKANDAR, UMAR Vivi Eulis Diana Vivi Eulis Diana Wahab, Iis Hamsir Ayub Wandani, Elliza Rizki Wilda Rizwani Winata, Hanafis Sastra Y, Hasyrif S Yani, Achmad Yusri Sapsuha Zai, Arifin Putra Zebua, Nilsya Febrika Zebua