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All Journal JURNAL KIMIA SAINS DAN APLIKASI Jurnal Ilmu Dasar Jurnal Sains dan Teknologi Pharmaciana: Jurnal Kefarmasian Journal of Islamic Pharmacy Turbo : Jurnal Program Studi Teknik Mesin Jurnal Pendidikan dan Ilmu Geografi Jurnal Ilmiah Manuntung KACANEGARA Jurnal Pengabdian pada Masyarakat PeTeKa JURNAL PENJAKORA JURNAL FARMASIMED (JFM) Jurnal Dunia Farmasi Jurnal Keperawatan Priority Jurnal Pengabdian Masyarakat Sains Indonesia (Indonesian Journal Of Science Community Services) Community Engagement and Emergence Journal (CEEJ) JURNAL PENELITIAN PERAWAT PROFESIONAL Jurnal Pembelajaran Pemberdayaan Masyarakat (JP2M) Journal of Computer Networks, Architecture and High Performance Computing Jurnal Disrupsi Bisnis Masjiduna : Junal Ilmiah Stidki Ar-Rahmah Jurnal Indah Sains dan Klinis Indonesian Journal of Society Engagement (IJSE) Jurnal Teknik Elektro (JTE) Jurnal Penelitian Inovatif Mejuajua Jurnal Kajian Ruang JPIG East Asian Journal of Multidisciplinary Research (EAJMR) Eksergi: Jurnal Teknik Energi Sinergi Polmed : Jurnal Ilmiah Teknik Mesin Lensa: Jurnal Kependidikan Fisika JURNAL KIMIA SAINTEK DAN PENDIDIKAN Jurnal Ekonomi dan Bisnis Samalewa: Jurnal Riset dan Kajian Manajemen Jurnal Mahasiswa Mengabdi (JIMAWAbdi) Jurnal Pengmas Kestra (JPK) Journal of Social Science Jurnal Manajemen Riset Inovasi Jurnal Intelek Dan Cendikiawan Nusantara JGEN : Jurnal Pengabdian Kepada Masyarakat Jurnal Indah Sains dan Klinis Jurnal Manajemen & Pendidikan Proceeding Of International Conference On Education, Society And Humanity Journal of Social Sciences and Economic Journal of Public Policy and Regional Government (JPPLG) Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Global Ten Public Health and Nursing Journal Jurnal Elektronik Pendidikan Matematika Tadulako Jurnal Ad'ministrare: Jurnal Pemikirian Ilmiah dan Pendidikan Administrasi Perkantoran Indonesian Journal of Advocacy and Legal Services International Journal of Advances in Artificial Intelligence and Machine Learning EL-HAYAH
Suprianto Suprianto
Institut Kesehatan Medistra Lubuk Pakam
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Tablet Kompresi Langsung Ekstrak Etanol Daun Salam (Syzygium polyanthum) Muhammad Gunawan; Suprianto; Samran; Cut Fatimah; Debi Melani; Sumardi
Jurnal Indah Sains dan Klinis Vol 2 No 3 (2021): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v2i3.31

Abstract

Indonesia's natural wealth that is efficacious in suppressing cholesterol, hypertension, diarrhea, gastritis and blood sugar is one of the bay leaves (Syzygium polyanthum Wight.). Tablets are preparations that are practical to use, easy to produce, pack, and distribute. The research was directed to make tablets of bay leaf ethanol extract (EEDS) by direct compression. EEDS tablets were made into four formulas with various fillers of lactose and Avicel PH 102, each 200 mg : 135 mg A); 250 mg : 105 mg (B); 300 mg : 55 mg (C); and 350 mg : 5 mg (D). The study showed that all formulas met the preformulation test requirements and tablet evaluation, D as the best formula. EEDS is made into tablets by direct compression.
Analisa Vitamin C dan Evaluasi Sediaan Tablet Effervescent Campuran Ekstrak Etanol Biji Jambu Biji Merah dan Putih (Psidium guajava L.) Hendri Faisal; Suprianto; Nur Aisyah Pitri; Sri Handayani; Dwi Setio Purnomo
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i1.40

Abstract

Effervescent tablets, CO2-producing tablets from the reaction of tablet constituents with their solvents. Red guava contains beta-carotene vitamin C is quite high, white guava is rich in vitamins, flavonoids, carotenoids, saponins, tannins, phenols, triterpenes, essential oils, fiber, and fatty acids. The study aimed at the comparison of vitamin C extract of red and white guava seeds (Psidium guavala. L). Powder evaluation includes flow time, angle of repose, compactibility. The evaluation of tablets included organoleptic, soluble time, weight uniformity, hardness, friability, pH, vitamin C content using UV spectrophotometry method. The results showed that the flow time test was 11.31-16 gram/second, the angle of repose was 33.02-34.92%; compactibility 7.59-16.9%; effervescent tablet preparation is round in shape, brown aroma, dark brown-brown color, slightly sweet taste, dissolving time 33.79- 89.53 seconds; hardness 4-5,4 kg; friability 0.04-0.9%; pH is close to neutral at pH 5.83-6.39; vitamin C content of red and white guava seeds were 37.86 mg/g and 42.32 mg/g, respectively. Red and white guava seed extract can be formulated into effervescent tablets and has vitamin C 0.19 – 0.28 mg/g
Evaluasi Stabilisator Agar-Agar dan CMC Sediaan Sirup Markisa Berastagi Suprianto; Muhammad Gunawan; Melati Yulia Kusumastuti; Cut Fatimah; Debi Meilani
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/b1pzvs47

Abstract

Fruit syrup is made from a sugar solution, the taste and aroma are determined by the freshness of the fruit. Fruit commonly used in making syrup has an attractive color, aroma and distinctive taste. Passion fruit (Passiflora edulis Sims.) has a distinctive taste and aroma, so it is widely processed into syrup. This study was to evaluate CMC and Agar-Agar stabilizers in the passion fruit syrup formula. Evaluation includes color, appearance, texture, taste and aroma and hedonic tests are carried out. The results showed that there were significant differences in the color, appearance, texture, taste and aroma of passion fruit syrup. Stabilizers CMC and Agar-Agar make the color, texture and appearance of the syrup better and more attractive. The result of hedonic test for ideal syrup concentration is S3 with 4 g of Agar and 6 g of CMC. The higher the concentration of CMC and Agar, the greater the viscosity of the syrup. The concentration of CMC and Agar-agar in a mixture of fruit juices gave significantly different effects on color, texture, appearance, taste and aroma
Formulasi dan Evaluasi Sediaan Sabun Padat Antiseptik Ekstrak Etanol Daun Kunyit Suprianto; Sumardi; Debi Meilani; Sri Rahayu
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i1.44

Abstract

The plant of findings turmeric (Curcuma longa) are often used as a traditional medicinal. The part of the turmeric plant that is often used is the rhizome. In addition to turmeric rhizome, turmeric leaves are also used as a flavoring dish. Among the benefits of turmeric leaves is as an antimicrobial. Soap is a surfactant used for washing and cleaning. Antiseptics are inhibitors for the growth and development of microorganisms that live on the surface of the body. The study was to determine which ethanol extract of turmeric leaves could be formulated into antiseptic solid soap preparations. This study used an experimental method, turmeric leaves were extracted with 70% ethanol. The formula made are 2.5%, 5%, 7.5%. The quality of the soap preparation was carried out by organoleptic tests, acidity, high foam and irritation. The results test showed that the solid soap did not have the aroma of turmeric leaves, the pH of the soap was 9.9-10.5; foam height with a concentration of 7.5% which is 7.3 cm; and solid soap preparations ethanol extract of turmeric leaves did not cause irritation. The extract of turmeric leaves can be formulated into solid soap preparations. It is recommended to add perfume to the formulation of solid soap preparations of turmeric leaf extract as an antiseptic.
Evaluasi Konsentrasi Karboksimetilselulosa Alginat Formula Pasta Gigi Antiseptik Ekstrak Etanol Daun Seledri (Apium graveolens L.) Samran; Suprianto; Muhammad Gunawan; Melati Yulia Kusumastuti
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i1.45

Abstract

Maceration of Celery leaves using 96% ethanol solvent was used to make the extract. Toothpaste is formulated with carboxymethylcellulose and alginate binders. The active ingredient in the form of ethanol extract from Celery leaves has the potential for antibacterial. This study was to evaluate the concentration of carboxymethylcellulose alginate in the preparation of antiseptic toothpaste of ethanol extract from Celery leaves. Evaluation of production results consisted of organoleptic, homogeneity, spreadability, foam formation, acidity and viscosity. The higher the concentration of carboxymethylcellulose, the lower the foam and spreadability and the higher the viscosity, while the alginate concentration is the opposite. Carboxymethylcellulose alginate affects the evaluation parameters of antiseptic toothpaste preparations ethanol extract of Celery leaves
Analisis Biaya Efektif Terapi Diare Pasien Rawat Inap RS Putri Hijau Medan Muhammad Gunawan; Suprianto; Melati Yulia Kusumastuti; Sumardi; Debi Meilani
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i1.46

Abstract

Diarrhea is characterized by the excretion of liquid stools with a frequency of three or more times a day, due to gastrointestinal infections due to food and water contaminated with microorganisms, or directly from humans due to poor sanitation. This study was to determine the characteristics of diarrhea patients, treatment and cost-effectiveness of treatment at Putri Hijau Hospital, Medan. The non-experimental research is descriptive and retrospective in nature of financial patient medical records from July to December 2018. Cost Effectiveness Analysis as a method of cost analysis. The characteristics of the patients obtained were 14 women (46.670%) and 16 men (53.33%). The effectiveness of New Diatabs (92.30%) and New Diatabs Metronidazole (94.11%). The cost of therapy with New Diatabs is Rp. 1,547,771/patient and New Diatabs Metronidazole is Rp. 1,562,590/patient. Average cost-effectiveness New Diatabs Rp. 190,345 and New Diatabs Metronidazole Rp. 183,060, so it is concluded that the cost-effective therapy is the use of the combination of New Diatabs Metronidazole compared to New Diatabs.
Uji Ekstrak Kulit Buah Mangga Arum Manis dalam Etanol pada Tumbuh Kembang Escherichia coli dan Salmonella typhi Mandike Ginting; Suprianto; Siti Fatimah Hanum; Debi Meilani; Maya Sartika
Jurnal Indah Sains dan Klinis Vol 3 No 2 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i2.56

Abstract

Antibacterial interferes with growth and development and even kills by interfering with microbial metabolism. The peel of Mangifera indica L.var. arum manis contains antibacterial flavonoids. Research for the detection of antibacterial activity of mango peel extract of arum manis varieties in ethanol on E. coli and S. typhi. The well diffusion method was used with concentrations of 20.0%, 30.0% and 40.0%; chloramphenicol as a positive control. The diameter of the inhibition zone as an indicator of E. coli activity was 12.83 mm; 12.93 mm; and 13.91 mm, against S. typhi 11.60 mm; 12.52 mm; and 13.40 mm at these concentrations, respectively. Ethanol extract of Mangifera indica L. var. arum manis has antibacterial activity of E. coli and S. typhi with strong inhibitory power, and without differences in concentration
Validasi Metode Spektrofotometri UV Penetapan Kadar Tablet Ranitidin HCl dalam HCl Sefryantonius Lase; Suprianto, Suprianto
Jurnal Indah Sains dan Klinis Vol 5 No 1 (2024): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v5i1.01

Abstract

Introduction: Ranitidine HCl tablets are widely available in the market. Ensuring the proper levels of active ingredients is crucial for ensuring the quality of medications. Objective: To find a reliable method for measuring the levels of Ranitidine HCl tablets in acidic solvents that meet validation standards, and to explore valid methods using ultraviolet spectrophotometry in acidic solvents. Methods: UV spectrophotometry with a UV detector at maximum wavelength was used. Two solvents were employed: 0.10 N HCl and 0.15 N HCl. Method validation included tests for linearity, accuracy, repeatability, precision, and selectivity. Results: The maximum wavelengths detected for each solvent were 225 nm and 226 nm, respectively. Validation results indicate excellent linearity, accuracy, and precision within the ranges of 0.9984 - 0.9998; 99.6% - 100.7%; 0.427% - 0.861%; 0.518% - 0.952%. The selectivity test yielded positive outcomes. The average Ranitidine HCl tablet levels were 98.2% for PT. Hexpharm Jaya and 98.4% for PT. Mutifa Medan, meeting the standards of the Indonesian Pharmacopoeia Edition VI. Conclusion: The method using a 0.10 N solvent for determining Ranitidine HCl tablet levels meets validation requirements and is suitable for practical application.
Pemeriksaan Cemaran Mikroba Susu Sapi Segar Daerah Limau Manis Tanjung Morawa Deli Serdang Muhammad Gunawan; Suprianto
Jurnal Indah Sains dan Klinis Vol 5 No 1 (2024): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v5i1.02

Abstract

Background: Milk serves as a crucial source of human nutrition, particularly for infants who rely on it before they can digest solid foods. The mammary glands of female mammals produce it and is typically characterized by its pure white appearance. Objective: This study aimed to assess the levels of mesophilic aerobic bacteria and yeast mould present in fresh cow's milk obtained from farms in Limau Manis Tanjung Morawa. Methods: The investigation into contamination levels employed the Total Plate Count (TPC) method for aerobic bacteria and the Yeast Mold Count (YMC) method, both of which are based on the guidelines outlined in the Indonesian National Standard (SNI) No. 3141.1 of 2011. Results: Findings revealed that the levels of aerobic mesophilic bacteria, as determined by the TPC method, met the stipulated requirements of SNI No. 3141.1 of 2011 across all five farms surveyed. However, the research utilizing the YMC method indicated that the yeast mould counts in the milk from all five farms did not meet the established criteria. Conclusion: The analysis of microbial contamination using the TPC and YMC methods demonstrated compliance and non-compliance, respectively, with the standards outlined in SNI No. 3141.1 of 2011.
Analisis Kualitatif BKO Deksametason pada Jamu Peningkat Selera Makan dengan Spektrofotometer FTIR Jelly Syahfitri; Suprianto
Jurnal Indah Sains dan Klinis Vol 5 No 2 (2024): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v5i2.01

Abstract

Background: Jamu, a traditional health service deeply ingrained in Indonesian culture, has been utilized for generations. Among the herbal remedies sought after by the public, herbal medicine aimed at enhancing appetite stands out. Unfortunately, the robust demand for these products is often exploited by manufacturers who incorporate pharmaceutical additives. Dexamethasone, a synthetic glucocorticoid renowned for its anti-inflammatory and immunosuppressant attributes, is frequently amalgamated with herbs to stimulate appetite. Its inclusion is prompted by its known side effect of moon face and its potential to enhance appetite with prolonged use. Objective: This research endeavors to ascertain the presence of dexamethasone in the herbal appetite stimulants available in the market within Lubuk Pakam District, Deli Serdang, North Sumatra. Method: Qualitative analysis of dexamethasone was conducted utilizing Fourier Transform Infra Red (FTIR) spectrophotometry. Results: The investigation revealed that several samples of appetite-enhancing herbal medicine suspected to contain dexamethasone indeed exhibited spectra akin to the standard comparison of dexamethasone. Conclusion: Among the ten samples of herbal appetite stimulants scrutinized, eight were found to contain dexamethasone, as evidenced by the congruence of their spectra and functional groups with the comparison standard for dexamethasone.
Co-Authors Abdul Latif Abdul Rahim Adek Chan Afriadi Afriadi Agustine, Nita Claudia Ahmad Hafizullah Ritonga Akhsal, Muhammad Alam Suhada Alam Suhada Alamsyah, Sayyidul Aulia Alfani, Andri Alizha Aisyah Ananda Sri Devy Ancel Mus Silaban Andilala Andraini, Galuh Anita Anita Anjur Falden Lingga Annas Reza Annas Reza Ardani Ardani Ardina Ardina Ardina Pakpahan Arie Wardhono Arinri Misnangin Sritala Ramadani Arinri Misnangin Sritala Ramadani As-Sidqi, Miftakhul Hidayatullah Atika, Nur Ayomi, Siti Azmi, Muhammad Farhan Bambang Purnomo Yanuarso BENNI ISKANDAR Bunga Nur Julianingtyas, Bunga Nur Cahyono, Bowo Eko Chan, Adek Cinde Ririh Windayu Cut Fatimah Cut Fatimah Cyndi Veronica DARMANSYAH . Darmawan, Sukma Adi De Lux Putra, Effendy Debi Meilani Debi Melani Derlina . Devi Purnama Sari Dewi Kartika Dewi Sartika Munthe Dian Zulkarnain Lubis Dikari Harita Dwi Fita Heriyawati Dwi Setio Purnomo Effendy De Lux Putra Eko Sutrisno, Eko Elliza Rizki Wandani Elvy Oktima Elvy Oktima Endang Subekti Endang Subekti Enny Fitriani Fadilah, Ilham risqi Fahad Fahad Fartimah, Siti Fauzi, Rafli Febriady, Andy Ferdiansah, Muhammad Vicky Fesri Damai Riang Laia Fesri Damai Riang Laia Fina Dheny Lantika Firnanda, Basyid Fitri Mayang Sari Fitriani Nasution Fitriani, Enny Gatot Kusjono Haerul Pathoni, Haerul Hakim, Syamsul Hamdani Hamdani Hanafi, Mohammad Iqbal Handrito , Radityo Putro Hapsari Peni Harianto, Bambang Bagus Harman, Anita Hasrat Masa Harefa Hendri Faisal Herliana Herlina H Herlina Herlina Hermansyah . Hetty Wahyuni Hunowu, Adam Husnul Khatimah I Gusti Putu Asto Buditjahjanto I Kadek Suardika I Made Budiarsa I.G.P Asto Buditjahjanto Ibana, Lukluk Ibana Ihsanul Hafiz Indra Ginting Indrasari, Hairuni Jainuddin, Jainuddin Jakub Tarigan Jakub Tarigan Jamaluddin Jelly Syahfitri Johannes Johannes Joko Wibowo Kantari, Losa Ade Kartika, Unit Three Kurniawansyah Kurniawansyah Kusjono, Gatot Kusmini Suprihatin Kusumastuti, Melati Yulia Leny, Leny Lestari, Wita Lidiya Sasmaita Sihotang Lili Nurmaliza Lilik Anifah Loetfia Dwi Rahariyani Lukman Hakim Lukmanul Hakim Luly Triningsih Mairani, Fridelly Mandike Ginting Mandike Ginting MARIFANI FITRI ARISA Maulana Muhammad Jogo Samudro Maya Annisa Lubis Maya Sartika Maya Sartika Melati Yulia Kusumastuti Melati Yulia Kusumastuti Merita Indrawati, Elsanda Mia Maelani Moch. Bahrudin Mohammad Hidayaturrahman Mubarak, Abdulah Mudakir, Kharis Muh. Hasbi Muhammad Deddy Harfiansyah Muhammad Deddy Harfiansyah Muhammad Gunawan Muhammad Gunawan MUHAMMAD HASBI Muiz, Ahmad Habibul Mulyadi, Syifaul Aini Musyarrofah, Wilda Muzakki, Naufal Nasir Nasir Nasrullah, Muh. Nasution, Lely Fitri Handayani Nicko, Abed Nilsya Febrika Zebua, Nilsya Febrika Ningsih, Risma Nining Sudiyarti Novia Susanti Novitasari, Intan Sekar Nur Aini, Intan Nur Aisyah Pitri Nur Asni Arti Nur Asni Arti Nurasyah Nurasyah Nurhayati Nurhayati Nurlela Petra Saragih Nurul Ratnawati, Nurul Nur’Adina Nur’Adina Nur’Adina Pangga, Dwi Panjaitan, John David Willy Peri Aisyah Zubaidi Permata, Yade Metri Pranata, Chandra Prihanto, Yusep Putri Addina Rachel Anastasia R Hutabarat Rahman, Khalifatur Ramli Ramli Rehanun Resaldi A, Devano Ilham Riesha, Riezky Army Rifa'i, Anggi Muhammad Rifqi Firmansyah, Rifqi Rillia Aisyah Haris Rini Agustina Riska Riska Risma Niswaty Risma Yeni Roos Nana Sucihati Rosary, A. Osfira Rotua Sumihar Sitorus Ruseni Ruth Mayana Rumanti Ruth Mayana Rumanti S, Ahmad Suryadi Sahrita Sahrita Said , Amal Samran, Samran Saputra, Zanuar Faudino Saragih, Safitri Sasilatha, T. Saswan, Munadi Agri Sefryantonius Lase Septian, Afan Maulana Sertin Prilda Sari Sandoro Sertin Prilda Sari Sandoro Setiawan, Bhayu Aji Shofian Syarifuddin Sindy Andriani Siregar, Dwiki Rifhardi Siregar, Riwandi Siregar, Suci Rahmadani Siti Fatimah Hanum Siti Nurbaya Siti Nurbaya Siti Rahmi, Siti Sri Handayani Sri Rahayu SRI RAHAYU Sudirman Sugiantiningsih, Anak Agung Putu Suhendra Tawarnate Sumardi Sumardi Sumardi . Sutji Rochaminah Syamruddin Syamruddin Syamsul, Darwin Syukur, Hendrodinus Widono Tambubolon, Regina Elianda Ubaid, Ahmad Hasan Ucok Hasian Refeiater Umniyah, Inas Alfiyatul Unit Three Kartini Vivi Eulis Diana Vivi Eulis Diana Wilda Rizwani Winarsih, Rini Winarsih Winata, Hanafis Sastra Yudairawan, Listyo Zai, Arifin Putra Zebua, Nilsya Febrika Zebua Zuhrie, Muhamad Syariffuddien Zulkia, Andipta Ahmad