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All Journal JURNAL KIMIA SAINS DAN APLIKASI Pharmaciana: Jurnal Kefarmasian Journal of Islamic Pharmacy Jurnal Maneksi (Management Ekonomi Dan Akuntansi) Momentum: Physics Education Journal JMM (Jurnal Masyarakat Mandiri) Jurnal Agrotek Tropika JUPE : Jurnal Pendidikan Mandala Literasi : Jurnal Ilmu Pendidikan JURNAL FARMASIMED (JFM) Jurnal Dunia Farmasi Jurnal Keperawatan Priority JENIUS (Jurnal Ilmiah Manajemen Sumber Daya Manusia) JURNAL PENELITIAN PERAWAT PROFESIONAL Jurnal Indah Sains dan Klinis Mejuajua Journal Of Business, Finance, and Economics (JBFE) Indonesian Journal of Innovation Studies International Journal of Research in Vocational Studies (IJRVOCAS) JURNAL KIMIA SAINTEK DAN PENDIDIKAN Jurnal Pengmas Kestra (JPK) Prosiding SEMNAS INOTEK (Seminar Nasional Inovasi Teknologi) Jurnal Indah Sains dan Klinis Jurnal Medika: Medika Jurnal Polimesin Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Global Ten Public Health and Nursing Journal Global Journal of Educational Technology (GJET) Jurnal Riset dan Pengabdian Interdisipliner
Suprianto Suprianto
Institut Kesehatan Medistra Lubuk Pakam
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Evaluasi Konsentrasi Karboksimetilselulosa Alginat Formula Pasta Gigi Antiseptik Ekstrak Etanol Daun Seledri (Apium graveolens L.) Samran; Suprianto; Muhammad Gunawan; Melati Yulia Kusumastuti
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i1.45

Abstract

Maceration of Celery leaves using 96% ethanol solvent was used to make the extract. Toothpaste is formulated with carboxymethylcellulose and alginate binders. The active ingredient in the form of ethanol extract from Celery leaves has the potential for antibacterial. This study was to evaluate the concentration of carboxymethylcellulose alginate in the preparation of antiseptic toothpaste of ethanol extract from Celery leaves. Evaluation of production results consisted of organoleptic, homogeneity, spreadability, foam formation, acidity and viscosity. The higher the concentration of carboxymethylcellulose, the lower the foam and spreadability and the higher the viscosity, while the alginate concentration is the opposite. Carboxymethylcellulose alginate affects the evaluation parameters of antiseptic toothpaste preparations ethanol extract of Celery leaves
Analisis Biaya Efektif Terapi Diare Pasien Rawat Inap RS Putri Hijau Medan Muhammad Gunawan; Suprianto; Melati Yulia Kusumastuti; Sumardi; Debi Meilani
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i1.46

Abstract

Diarrhea is characterized by the excretion of liquid stools with a frequency of three or more times a day, due to gastrointestinal infections due to food and water contaminated with microorganisms, or directly from humans due to poor sanitation. This study was to determine the characteristics of diarrhea patients, treatment and cost-effectiveness of treatment at Putri Hijau Hospital, Medan. The non-experimental research is descriptive and retrospective in nature of financial patient medical records from July to December 2018. Cost Effectiveness Analysis as a method of cost analysis. The characteristics of the patients obtained were 14 women (46.670%) and 16 men (53.33%). The effectiveness of New Diatabs (92.30%) and New Diatabs Metronidazole (94.11%). The cost of therapy with New Diatabs is Rp. 1,547,771/patient and New Diatabs Metronidazole is Rp. 1,562,590/patient. Average cost-effectiveness New Diatabs Rp. 190,345 and New Diatabs Metronidazole Rp. 183,060, so it is concluded that the cost-effective therapy is the use of the combination of New Diatabs Metronidazole compared to New Diatabs.
Uji Ekstrak Kulit Buah Mangga Arum Manis dalam Etanol pada Tumbuh Kembang Escherichia coli dan Salmonella typhi Mandike Ginting; Suprianto; Siti Fatimah Hanum; Debi Meilani; Maya Sartika
Jurnal Indah Sains dan Klinis Vol 3 No 2 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i2.56

Abstract

Antibacterial interferes with growth and development and even kills by interfering with microbial metabolism. The peel of Mangifera indica L.var. arum manis contains antibacterial flavonoids. Research for the detection of antibacterial activity of mango peel extract of arum manis varieties in ethanol on E. coli and S. typhi. The well diffusion method was used with concentrations of 20.0%, 30.0% and 40.0%; chloramphenicol as a positive control. The diameter of the inhibition zone as an indicator of E. coli activity was 12.83 mm; 12.93 mm; and 13.91 mm, against S. typhi 11.60 mm; 12.52 mm; and 13.40 mm at these concentrations, respectively. Ethanol extract of Mangifera indica L. var. arum manis has antibacterial activity of E. coli and S. typhi with strong inhibitory power, and without differences in concentration
Validasi Metode Spektrofotometri UV Penetapan Kadar Tablet Ranitidin HCl dalam HCl Sefryantonius Lase; Suprianto, Suprianto
Jurnal Indah Sains dan Klinis Vol 5 No 1 (2024): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v5i1.01

Abstract

Introduction: Ranitidine HCl tablets are widely available in the market. Ensuring the proper levels of active ingredients is crucial for ensuring the quality of medications. Objective: To find a reliable method for measuring the levels of Ranitidine HCl tablets in acidic solvents that meet validation standards, and to explore valid methods using ultraviolet spectrophotometry in acidic solvents. Methods: UV spectrophotometry with a UV detector at maximum wavelength was used. Two solvents were employed: 0.10 N HCl and 0.15 N HCl. Method validation included tests for linearity, accuracy, repeatability, precision, and selectivity. Results: The maximum wavelengths detected for each solvent were 225 nm and 226 nm, respectively. Validation results indicate excellent linearity, accuracy, and precision within the ranges of 0.9984 - 0.9998; 99.6% - 100.7%; 0.427% - 0.861%; 0.518% - 0.952%. The selectivity test yielded positive outcomes. The average Ranitidine HCl tablet levels were 98.2% for PT. Hexpharm Jaya and 98.4% for PT. Mutifa Medan, meeting the standards of the Indonesian Pharmacopoeia Edition VI. Conclusion: The method using a 0.10 N solvent for determining Ranitidine HCl tablet levels meets validation requirements and is suitable for practical application.
Pemeriksaan Cemaran Mikroba Susu Sapi Segar Daerah Limau Manis Tanjung Morawa Deli Serdang Muhammad Gunawan; Suprianto
Jurnal Indah Sains dan Klinis Vol 5 No 1 (2024): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v5i1.02

Abstract

Background: Milk serves as a crucial source of human nutrition, particularly for infants who rely on it before they can digest solid foods. The mammary glands of female mammals produce it and is typically characterized by its pure white appearance. Objective: This study aimed to assess the levels of mesophilic aerobic bacteria and yeast mould present in fresh cow's milk obtained from farms in Limau Manis Tanjung Morawa. Methods: The investigation into contamination levels employed the Total Plate Count (TPC) method for aerobic bacteria and the Yeast Mold Count (YMC) method, both of which are based on the guidelines outlined in the Indonesian National Standard (SNI) No. 3141.1 of 2011. Results: Findings revealed that the levels of aerobic mesophilic bacteria, as determined by the TPC method, met the stipulated requirements of SNI No. 3141.1 of 2011 across all five farms surveyed. However, the research utilizing the YMC method indicated that the yeast mould counts in the milk from all five farms did not meet the established criteria. Conclusion: The analysis of microbial contamination using the TPC and YMC methods demonstrated compliance and non-compliance, respectively, with the standards outlined in SNI No. 3141.1 of 2011.
Analisis Kualitatif BKO Deksametason pada Jamu Peningkat Selera Makan dengan Spektrofotometer FTIR Jelly Syahfitri; Suprianto
Jurnal Indah Sains dan Klinis Vol 5 No 2 (2024): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v5i2.01

Abstract

Background: Jamu, a traditional health service deeply ingrained in Indonesian culture, has been utilized for generations. Among the herbal remedies sought after by the public, herbal medicine aimed at enhancing appetite stands out. Unfortunately, the robust demand for these products is often exploited by manufacturers who incorporate pharmaceutical additives. Dexamethasone, a synthetic glucocorticoid renowned for its anti-inflammatory and immunosuppressant attributes, is frequently amalgamated with herbs to stimulate appetite. Its inclusion is prompted by its known side effect of moon face and its potential to enhance appetite with prolonged use. Objective: This research endeavors to ascertain the presence of dexamethasone in the herbal appetite stimulants available in the market within Lubuk Pakam District, Deli Serdang, North Sumatra. Method: Qualitative analysis of dexamethasone was conducted utilizing Fourier Transform Infra Red (FTIR) spectrophotometry. Results: The investigation revealed that several samples of appetite-enhancing herbal medicine suspected to contain dexamethasone indeed exhibited spectra akin to the standard comparison of dexamethasone. Conclusion: Among the ten samples of herbal appetite stimulants scrutinized, eight were found to contain dexamethasone, as evidenced by the congruence of their spectra and functional groups with the comparison standard for dexamethasone.
Uji Kemurnian Ekstrak Galaktomanan Biji Durian (Durio zibethinus L.) dengan Metode Luff Schoorl Zebua, Nilsya Febrika; Sumardi; Suprianto; Alizha Aisyah
Jurnal Indah Sains dan Klinis Vol 3 No 3 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i3.01

Abstract

Introduction: Galactomannan is found in the endosperm of seeds in the Fabaceae family, for example durian seeds (Durio zibethinus L). Galactomannan is a natural polysaccharide as an additional ingredient. Objective: The research aims to determine the Galactomannan content in Durian seeds isolated by chromatography and to determine the Galactomannan content in Durian seeds using the Luff Schoorl method. Methods: The research was carried out by extracting galactomannan from Durian seeds using distilled water by heating them for 5 minutes. Purification was carried out using paper chromatography with various variations of mobile phases, namely BEW (Butanol: Ethanol: Water), BAW (Butanol: Acetic acid: Water), Glacial acetic acid 10%, Glacial acetic acid 50%, HCl 10%, HCl 20% and Thin layer chromatography with the mobile phase n-Hexane: Ethylacetate at varying ratios of 3:7 and 7:3. Purity testing is carried out using the Luff Scroorl method. Results: Extraction of 500 g of durian seeds produces 1,8% Galactomannan. The levels before and after inversion using the Luff Schoorl method were respectively 8.0131 and 7.0679 mg/mg. Conclusion: Galactomannan can be obtained from extracting durian seeds and its inverse using the Luff Scroorl method.
Analisis Kadar Kalsium, Kalium, Besi Akibat Variasi Waktu Rendam Kacang Produksi Susu Almond secara Spektrofotometri Serapan Atom Yade Metri Permata; Suprianto; Ananda Sri Devy
Jurnal Indah Sains dan Klinis Vol 3 No 3 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i3.02

Abstract

Background: Calcium, potassium and iron can be obtained from milk, nuts, eggs, fish, fruit vegetables, green vegetables and products needed by the human body which play a role in maintaining body functions, including cells, tissues, organs and overall function. Objective: Research to determine the levels of these minerals in almond milk using atomic absorption spectrophotometry (AAS). Method: Almonds were soaked for 4, 8, and 12 hours respectively for almond milk 1, 2, and 3 (SA1, SA2, and SA3) and Almendrola packaged milk (SA4). Samples were wet digested with concentrated HNO3. Analysis of calcium, potassium and iron levels using AAS with an air-acetylene flame was 422.7; 766.5; and 248.3 nm for calcium, potassium and iron respectively. Validated methods include accuracy, precision, LOD and LOQ. Results: Results of determining the mineral content of almond milk (mg/100g) for calcium, potassium and iron respectively (2.6551 ± 0.0925; 5.5464 ± 0.3178; 5.8866 ± 0.03805; and 4.5842 ± 0.2590), (2.4096 ± 0.0551; 2.5150 ± 0.0115; 2.6551 ± 0.0557; and 2.5150 ± 0.0551), and (0.3202 ± 0.0282; 0.3307 ± 0.0048; 0.3344 ± 0.011; and 0.3183 ± 0.0045). Conclusion: Validation of the method meets the requirements, soaking impacts increasing mineral levels in Almond Milk, and there are significant differences in calcium, potassium and iron levels in the milk.
Optimasi Potensi Anti Escherichia coli dan Staphylococcus aureus Kombinasi Ekstrak Etil Asetat Allium cepa dan Allium sativum Suprianto; Dikari Harita; Dwi Setio Purnomo
Jurnal Indah Sains dan Klinis Vol 4 No 1 (2023): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v4i1.01

Abstract

Background: Natural antibiotics are often used as an alternative therapy. Microbial infections are the main cause of mortality and morbidity in developing countries, including Indonesia. Staphylococcus aureus and Escherichia coli are two microbes that are often used for testing natural antibiotics. Objective: This study aims to optimize the combination of shallot and white onion extracts to potentially inhibit bacterial growth and development. Method: This study used a randomised design method of a combination of onion and garlic extracts tested based on the inhibitory area response. Results: The combination of shallot and white onion ethyl acetate extracts showed activity as an inhibitor of bacterial growth and development. The combination of EBM and EBP provides an inhibitory response against Escherichia coli (X2) and Staphylococcus aureus (X3). Conclusion: Combining EBM and EBP can inhibit the growth and development of Escherichia coli and Staphylococcus aureus. The best combination as an inhibitor of growth and development was Escherichia coli (X2; 14.53 mm) and Staphylococcus aures (X3: 15.7 mm), respectively
Gambaran Pemakaian Bahan Medis Habis Pakai Gudang Depo Farmasi Rindu B RSUP H. Adam Malik Medan Berdasarkan Standar Operasional Prosedur Tahun 2019 Anjur Falden Lingga; Adek Chan; Suprianto
Jurnal Indah Sains dan Klinis Vol 4 No 2 (2023): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v4i2.02

Abstract

Introduction: Managing consumable medical materials involves coordinating activities to ensure they work well together, aiming for effective and efficient management. This ensures doctors always have an adequate supply of high-quality consumable medical materials to support quality services. Objective: This study aimed to describe the Utilization of Consumable Medical Materials at the Pharmacy Warehouse of Depo Rindu B H. Based on the 2019 Standard Operating Procedures (SOP), Adam Malik Hospital Medan. Methods: The study utilized direct observation and interviews conducted from May to July 2019. Results: Expenditures in January, February, and March 2019 were 25,726, 22,332, and 24,503 units respectively. Distribution is facilitated through online prescribing and delivery. Observations indicated the use of storage systems such as First In First Out (FIFO) and First Expired First Out (FEFO), organised by dosage form, alphabetical order, and category. Conclusion: Procurement at the Depo Rindu B pharmaceutical warehouse at H. Adam Malik Hospital Medan during the 2019 period was by the applicable 2019 SOP
Co-Authors A., Ade Ayu Fitriana Abdul Rahim Adek Chan Adinda Seftia Afriadi Afriadi Agung Ardiansyah, Agung Agus Kristina Ahmad Hafizullah Ritonga Ahmad Sumantri - Alam Suhada Alam Suhada Alizha Aisyah Amal Said Ananda Sri Devy Ancel Mus Silaban Andilala Andraini, Galuh Andy Febriadi Anita Anita Anjur Falden Lingga Annas Reza Annas Reza Ardina Ardina Ardina Pakpahan Arinri Misnangin Sritala Ramadani Arinri Misnangin Sritala Ramadani Atika, Nur Atmaja, Hengki Atmanegara, Akhmad Prasetya Azzahra, Innayah Bagus Bagus, Bagus BENNI ISKANDAR Bimantoro, Zurdan Budi Harianto, Budi Bunda, Yola Permata Chan, Adek Chandra Pranata Cut Fatimah Cut Fatimah Cyndi Veronica Darmawati Darmawati De Lux Putra, Effendy Debi Meilani Debi Melani Derlina . Devi Purnama Sari Dewi Kartika Dewi Sartika Munthe Dian Zulkarnain Lubis Didi Darmadi, Didi Dikari Harita Dwi Setio Purnomo Effendy De Lux Putra Elvy Oktima Elvy Oktima Endang Subekti Endang Subekti Enny Fitriani Fadilasyah, Dimas Afrizal Fahmi, Muhammad Ikhwan Febriady, Andy Fesri Damai Riang Laia Fesri Damai Riang Laia Fina Dheny Lantika Fitri Mayang Sari Fitriani Nasution Fitriani, Enny Fridelly Mairani Apt Hafiz Luthfi Hasrat Masa Harefa Helda Ibramin Hendri Faisal Henry Toruan - Herliana Herlina H Herlina Herlina Herman Jufri Andi, Herman Jufri Hermansyah . Hermawan, Love Retno Herri Trisna Frianto, Herri Trisna Herwin Herwin, Herwin Hery Novpriansyah Hetty Wahyuni Hidayani, Mesalina Tri Ihsanul Hafiz Indra Ginting Jakub Tarigan Jakub Tarigan Jelly Syahfitri Johannes Johannes Joko Wibowo Kresna Shifa Usodri Kurniawansyah, Kurniawansyah Kusumastuti, Melati Yulia Leny, Leny Lestari, Wita Lidiya Sasmaita Sihotang Lili Nurmaliza Lisa Syafrida Lukmanul Hakim Luluk Widarti Maelani, Mia Manalu, Joko C.H Mandike Ginting Mandike Ginting Marbun, Intan Coni Caroline Maya Annisa Lubis Maya Sartika Maya Sartika Meidi Wani Lestari, Meidi Wani Melati Yulia Kusumastuti Melati Yulia Kusumastuti Muhammad Deddy Harfiansyah Muhammad Deddy Harfiansyah Muhammad Fadlan Siregar Muhammad Gunawan Muhammad Gunawan Nadiya Arifa Rahma Nainggolan, Angel M. Nasution, Lely Fitri Handayani Nilsya Febrika Zebua, Nilsya Febrika Nindha Ayu Berlianti Nur Afni Afrianti Nur Afni Afrianti Nur Aisyah Pitri Nur Asni Arti Nur Asni Arti Nurasyah Nurasyah Nurlela Petra Saragih Nur’Adina Nur’Adina Nur’Adina Peranginangin, Siwan Edi A. Peri Aisyah Zubaidi Permata, Yade Metri Pranata, Chandra Prasetiyo, Bagus Prayoga, Mirza Kirma Putri Addina Rachel Anastasia R Hutabarat Rahmawati, Eka Fauziah Ramly, Amisbah Rante, Neli Riany, Meutia Risma Yeni Roby Fernandi Rotua Sumihar Sitorus Rusdi Evizal Ruseni Ruth Mayana Rumanti Ruth Mayana Rumanti S. Ida Kholida Sadewa, Wahyu Digda Sahrita Sahrita Salim, Helmi Agus Samran, Samran Saragih, Safitri Sefryantonius Lase Sertin Prilda Sari Sandoro Sertin Prilda Sari Sandoro Shofian Syarifuddin simanjuntak, benrad edwin Simarmata, Aditya D Sindy Andriani Siregar, Riwandi Siregar, Suci Rahmadani Siringoringo, Michael R.S. Siti Fatimah Hanum Siti Maemonah Siti Nurbaya Siti Nurbaya Sitorus, Irfan Sri Handayani Sri Rahayu SRI RAHAYU Sri Wulandari Sri Yusnaini Sucihati, Roos Nana Sudiyarti, Nining Suhendra Tawarnate Sumardi Sumardi Sumardi . Syahputra, Syofyan Anwar Syamsul, Darwin Tambubolon, Regina Elianda Tandaditya Ariefandra Airlangga Tinambunan, Lukas A. Vivi Eulis Diana Vivi Eulis Diana Wandani, Elliza Rizki Wenehenubu, Fitalis Ekhy Wilda Rizwani Winata, Hanafis Sastra Zaenuddin Hudi Prasojo Zai, Arifin Putra Zaqyah, Irene Zebua, Nilsya Febrika Zebua