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All Journal JURNAL KIMIA SAINS DAN APLIKASI Pharmaciana: Jurnal Kefarmasian Journal of Islamic Pharmacy JURNAL FARMASIMED (JFM) Jurnal Dunia Farmasi Jurnal Keperawatan Priority JURNAL PENELITIAN PERAWAT PROFESIONAL Jurnal Indah Sains dan Klinis Mejuajua JURNAL KIMIA SAINTEK DAN PENDIDIKAN Jurnal Pengmas Kestra (JPK) Pangripta Jurnal Ilmiah Kajian Perencanaan Pembangunan Jurnal Indah Sains dan Klinis Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Suprianto Suprianto
Institut Kesehatan Medistra Lubuk Pakam
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Economics, Econometrics & Finance Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Potensi Antibakteri Kombinan Zingiber officinale var. Rubrum dengan Cinnamomum burmannii terhadap Staphylococcus aureus Ruth Mayana Rumanti; Suprianto; Jakub Tarigan; Arinri Misnangin Sritala Ramadani
Jurnal Indah Sains dan Klinis Vol 2 No 1 (2021): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v2i1.8

Abstract

Red Ginger (Zingiber officinalevar. Rubrum) and Cinnamon (Cinnamomum burmannii) contain alkaloids, flavonoids, saponins, tannins, triterpenoids and essential oils. which is antibacterial that causes pharyngitis by Staphylococcus aureus. This study aims to determine the antibacterial potency of the combination of Red Ginger (Zingiberofficinalevar. Rubrum) and Cinnamon (Cinnamomum burmannii) extract against Staphylococcus aureus. Experimental research includes the extraction of the compound components in red ginger and cinnamon by maceration with 70% ethanol. Inhibition was tested bydiffusion method. Combination of concentration of Red Ginger and Cinnamon extracts of 5%:40%; 10%:30%; 20%:20%; 30%:10% and 40%:5%. The combination of red ginger and cinnamon extract has antibacterial activity against pharyngitis-causing bacteria, namely Staphylococcus aureuswith a strong response at a concentration of 5%:40%
Kompleksometri Kalsium dan SSA Timbal Beberapa Depot Air Isi Ulang di Medan Nur’Adina; Hendri Faisal; Suprianto
Jurnal Indah Sains dan Klinis Vol 2 No 2 (2021): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v2i2.19

Abstract

Calcium minerals play an important role in maintaining body functions, while Lead is a dangerous heavy metal. The research was aimed at determining the levels of Calcium and Lead from several refill water depots in Medan. Calcium complexometry and lead AAS as their respective assay methods. Research shows calcium levels are 10.3-29.3 mg/L, correlation coefficient is 0.9928, and no lead is found in refill drinking water. Calcium levels do not meet the requirements, while lead levels still meet the WHO requirements.
Formulasi Sediaan Eyebrow Cream Arang Aktif Batok Kelapa Sertin Prilda Sari Sandoro; Suprianto; Sumardi
Jurnal Indah Sains dan Klinis Vol 2 No 2 (2021): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v2i2.26

Abstract

Eyebrow cream (EC) is one of the decorative cosmetics applied to the eyebrows using a brush for the purpose of giving color and emphasizing the shape of the eyebrows. EC is one of the practical preparations to fill in empty eyebrow hairs. The research was conducted of formulating activated charcoal into EC. The research method includes the formulation and evaluation of EC results from coconut shell activated charcoal at concentrations of activated charcoal 1%, 3%, 5% and 7%. Evaluation includes: organoleptic, homogeneity, irritation and pH of Eyebrow Cream. The organoleptic showed that the color of the preparation at a concentration of 1% -7% was black to dark black, with a cocoa oleum aroma, and a semi-solid texture. The pH of the preparation is 4.5-6.5 with good homogeneity. The preparation did not show irritation to the skin of volunteers. The study provide information that activated charcoal can be formulated into EC preparations. Coconut shell activated charcoal can be formulated in the form of eyebrow cream. The preparation of eyebrow cream does not cause irritation and is safe.
Tablet Kompresi Langsung Ekstrak Etanol Daun Salam (Syzygium polyanthum) Muhammad Gunawan; Suprianto; Samran; Cut Fatimah; Debi Melani; Sumardi
Jurnal Indah Sains dan Klinis Vol 2 No 3 (2021): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v2i3.31

Abstract

Indonesia's natural wealth that is efficacious in suppressing cholesterol, hypertension, diarrhea, gastritis and blood sugar is one of the bay leaves (Syzygium polyanthum Wight.). Tablets are preparations that are practical to use, easy to produce, pack, and distribute. The research was directed to make tablets of bay leaf ethanol extract (EEDS) by direct compression. EEDS tablets were made into four formulas with various fillers of lactose and Avicel PH 102, each 200 mg : 135 mg A); 250 mg : 105 mg (B); 300 mg : 55 mg (C); and 350 mg : 5 mg (D). The study showed that all formulas met the preformulation test requirements and tablet evaluation, D as the best formula. EEDS is made into tablets by direct compression.
Analisa Vitamin C dan Evaluasi Sediaan Tablet Effervescent Campuran Ekstrak Etanol Biji Jambu Biji Merah dan Putih (Psidium guajava L.) Hendri Faisal; Suprianto; Nur Aisyah Pitri; Sri Handayani; Dwi Setio Purnomo
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i1.40

Abstract

Effervescent tablets, CO2-producing tablets from the reaction of tablet constituents with their solvents. Red guava contains beta-carotene vitamin C is quite high, white guava is rich in vitamins, flavonoids, carotenoids, saponins, tannins, phenols, triterpenes, essential oils, fiber, and fatty acids. The study aimed at the comparison of vitamin C extract of red and white guava seeds (Psidium guavala. L). Powder evaluation includes flow time, angle of repose, compactibility. The evaluation of tablets included organoleptic, soluble time, weight uniformity, hardness, friability, pH, vitamin C content using UV spectrophotometry method. The results showed that the flow time test was 11.31-16 gram/second, the angle of repose was 33.02-34.92%; compactibility 7.59-16.9%; effervescent tablet preparation is round in shape, brown aroma, dark brown-brown color, slightly sweet taste, dissolving time 33.79- 89.53 seconds; hardness 4-5,4 kg; friability 0.04-0.9%; pH is close to neutral at pH 5.83-6.39; vitamin C content of red and white guava seeds were 37.86 mg/g and 42.32 mg/g, respectively. Red and white guava seed extract can be formulated into effervescent tablets and has vitamin C 0.19 – 0.28 mg/g
Evaluasi Stabilisator Agar-Agar dan CMC Sediaan Sirup Markisa Berastagi Suprianto; Muhammad Gunawan; Melati Yulia Kusumastuti; Cut Fatimah; Debi Meilani
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/b1pzvs47

Abstract

Fruit syrup is made from a sugar solution, the taste and aroma are determined by the freshness of the fruit. Fruit commonly used in making syrup has an attractive color, aroma and distinctive taste. Passion fruit (Passiflora edulis Sims.) has a distinctive taste and aroma, so it is widely processed into syrup. This study was to evaluate CMC and Agar-Agar stabilizers in the passion fruit syrup formula. Evaluation includes color, appearance, texture, taste and aroma and hedonic tests are carried out. The results showed that there were significant differences in the color, appearance, texture, taste and aroma of passion fruit syrup. Stabilizers CMC and Agar-Agar make the color, texture and appearance of the syrup better and more attractive. The result of hedonic test for ideal syrup concentration is S3 with 4 g of Agar and 6 g of CMC. The higher the concentration of CMC and Agar, the greater the viscosity of the syrup. The concentration of CMC and Agar-agar in a mixture of fruit juices gave significantly different effects on color, texture, appearance, taste and aroma
Formulasi dan Evaluasi Sediaan Sabun Padat Antiseptik Ekstrak Etanol Daun Kunyit Suprianto; Sumardi; Debi Meilani; Sri Rahayu
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i1.44

Abstract

The plant of findings turmeric (Curcuma longa) are often used as a traditional medicinal. The part of the turmeric plant that is often used is the rhizome. In addition to turmeric rhizome, turmeric leaves are also used as a flavoring dish. Among the benefits of turmeric leaves is as an antimicrobial. Soap is a surfactant used for washing and cleaning. Antiseptics are inhibitors for the growth and development of microorganisms that live on the surface of the body. The study was to determine which ethanol extract of turmeric leaves could be formulated into antiseptic solid soap preparations. This study used an experimental method, turmeric leaves were extracted with 70% ethanol. The formula made are 2.5%, 5%, 7.5%. The quality of the soap preparation was carried out by organoleptic tests, acidity, high foam and irritation. The results test showed that the solid soap did not have the aroma of turmeric leaves, the pH of the soap was 9.9-10.5; foam height with a concentration of 7.5% which is 7.3 cm; and solid soap preparations ethanol extract of turmeric leaves did not cause irritation. The extract of turmeric leaves can be formulated into solid soap preparations. It is recommended to add perfume to the formulation of solid soap preparations of turmeric leaf extract as an antiseptic.
Evaluasi Konsentrasi Karboksimetilselulosa Alginat Formula Pasta Gigi Antiseptik Ekstrak Etanol Daun Seledri (Apium graveolens L.) Samran; Suprianto; Muhammad Gunawan; Melati Yulia Kusumastuti
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i1.45

Abstract

Maceration of Celery leaves using 96% ethanol solvent was used to make the extract. Toothpaste is formulated with carboxymethylcellulose and alginate binders. The active ingredient in the form of ethanol extract from Celery leaves has the potential for antibacterial. This study was to evaluate the concentration of carboxymethylcellulose alginate in the preparation of antiseptic toothpaste of ethanol extract from Celery leaves. Evaluation of production results consisted of organoleptic, homogeneity, spreadability, foam formation, acidity and viscosity. The higher the concentration of carboxymethylcellulose, the lower the foam and spreadability and the higher the viscosity, while the alginate concentration is the opposite. Carboxymethylcellulose alginate affects the evaluation parameters of antiseptic toothpaste preparations ethanol extract of Celery leaves
Analisis Biaya Efektif Terapi Diare Pasien Rawat Inap RS Putri Hijau Medan Muhammad Gunawan; Suprianto; Melati Yulia Kusumastuti; Sumardi; Debi Meilani
Jurnal Indah Sains dan Klinis Vol 3 No 1 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i1.46

Abstract

Diarrhea is characterized by the excretion of liquid stools with a frequency of three or more times a day, due to gastrointestinal infections due to food and water contaminated with microorganisms, or directly from humans due to poor sanitation. This study was to determine the characteristics of diarrhea patients, treatment and cost-effectiveness of treatment at Putri Hijau Hospital, Medan. The non-experimental research is descriptive and retrospective in nature of financial patient medical records from July to December 2018. Cost Effectiveness Analysis as a method of cost analysis. The characteristics of the patients obtained were 14 women (46.670%) and 16 men (53.33%). The effectiveness of New Diatabs (92.30%) and New Diatabs Metronidazole (94.11%). The cost of therapy with New Diatabs is Rp. 1,547,771/patient and New Diatabs Metronidazole is Rp. 1,562,590/patient. Average cost-effectiveness New Diatabs Rp. 190,345 and New Diatabs Metronidazole Rp. 183,060, so it is concluded that the cost-effective therapy is the use of the combination of New Diatabs Metronidazole compared to New Diatabs.
Uji Ekstrak Kulit Buah Mangga Arum Manis dalam Etanol pada Tumbuh Kembang Escherichia coli dan Salmonella typhi Mandike Ginting; Suprianto; Siti Fatimah Hanum; Debi Meilani; Maya Sartika
Jurnal Indah Sains dan Klinis Vol 3 No 2 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i2.56

Abstract

Antibacterial interferes with growth and development and even kills by interfering with microbial metabolism. The peel of Mangifera indica L.var. arum manis contains antibacterial flavonoids. Research for the detection of antibacterial activity of mango peel extract of arum manis varieties in ethanol on E. coli and S. typhi. The well diffusion method was used with concentrations of 20.0%, 30.0% and 40.0%; chloramphenicol as a positive control. The diameter of the inhibition zone as an indicator of E. coli activity was 12.83 mm; 12.93 mm; and 13.91 mm, against S. typhi 11.60 mm; 12.52 mm; and 13.40 mm at these concentrations, respectively. Ethanol extract of Mangifera indica L. var. arum manis has antibacterial activity of E. coli and S. typhi with strong inhibitory power, and without differences in concentration
Co-Authors Abdul Rahim Adek Chan Adek Chan Adek Chan Adek Chan Afriadi Afriadi Ahmad Hafizullah Ritonga Aisy, Auliya Hasna Rahadatul Alam Suhada Alam Suhada Alizha Aisyah Ananda Sri Devy Ancel Mus Silaban Andilala Andraini, Galuh Anita Anita Anjur Falden Lingga Annas Reza Annas Reza Ardina Ardina Ardina Pakpahan Arifin Putra Zai Arinri Misnangin Sritala Ramadani Arinri Misnangin Sritala Ramadani Atika, Nur BENNI ISKANDAR Chan, Adek Cut Fatimah Cut Fatimah Darwin Syamsul De Lux Putra, Effendy Debi Meilani Debi Melani Derlina . Devi Purnama Sari Dewi Kartika Dewi Sartika Munthe Dian Zulkarnain Lubis Dikari Harita Dwi Setio Purnomo Dwi Setio Purnomo Elvy Oktima Elvy Oktima Endang Subekti Endang Subekti Enny Fitriani Febriady, Andy Fesri Damai Riang Laia Fesri Damai Riang Laia Fina Dheny Lantika Fitri Mayang Sari Fitriani Nasution Fitriani, Enny Fridelly Mairani Hasrat Masa Harefa Hendri Faisal Hendri Faisal Herliana Herlina H Herlina Herlina Hermansyah . Hetty Wahyuni Ihsanul Hafiz Indra Ginting Jakub Tarigan Jakub Tarigan Jelly Syahfitri Johannes Johannes Joko Wibowo Kurniawansyah, Kurniawansyah Kusumastuti, Melati Yulia Leny, Leny Lestari, Wita Lili Nurmaliza Lukmanul Hakim M. Deddy Harfiansyah Maelani, Mia Mandike Ginting Mandike Ginting Maya Annisa Lubis Maya Sartika Maya Sartika Melati Yulia Kusumastuti Melati Yulia Kusumastuti Muhammad Gunawan Muhammad Gunawan Muhammad Gunawan Nasution, Lely Fitri Handayani Nilsya Febrika Zebua Zebua Nilsya Febrika Zebua, Nilsya Febrika Nur Aisyah Pitri Nur Asni Arti Nur Asni Arti Nurasyah Nurasyah Nurlela Petra Saragih Nur’Adina Nur’Adina Nur’Adina Peri Aisyah Zubaidi Pranata, Chandra Putri Addina Rachel Anastasia R Hutabarat Regina Elianda Tambubolon Risma Yeni Rotua Sumihar Sitorus Ruseni Ruth Mayana Rumanti Ruth Mayana Rumanti Safitri Saragih Sahrita Sahrita Samran, Samran Sefryantonius Lase Sertin Prilda Sari Sandoro Sertin Prilda Sari Sandoro Shofian Syarifuddin Sindy Andriani Siregar, Riwandi Siti Fatimah Hanum Siti Fatimah Hanum Siti Nurbaya Sri Handayani Sri Rahayu Sri Rahayu Suci Rahmadani Siregar Sucihati, Roos Nana Sudiyarti, Nining Suhendra Tawarnate Sumardi Sumardi Sumardi Sumardi Sumardi Sumardi . Sumardi Sumardi Swasono Rahardjo Syamsul, Darwin Vivi Eulis Diana Vivi Eulis Diana Wandani, Elliza Rizki Wilda Rizwani Winata, Hanafis Sastra Yade Metri Permata