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All Journal Jurnal Ilmu Pertanian Indonesia ACTA VETERINARIA INDONESIANA Jurnal Sain Veteriner Buletin Peternakan Jurnal MIPA JITRO (Jurnal Ilmiah dan Teknologi Peternakan Tropis) PROSIDING SEMINAR KIMIA Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) Bioma : Jurnal Biologi Indonesia ARSHI Veterinary Letters Jambura Physics Journal JCPS (Journal of Current Pharmaceutical Sciences) Jurnal Fisika dan Terapannya Jurnal Abdimas ADPI Sains dan Teknologi Jurnal Pusat Inovasi Masyarakat Jurnal Kedokteran Hewan Jurnal Veteriner Nusantara Current Biomedicine
koekoeh santoso
IPB University
Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Education Electrical & Electronics Engineering Energy Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Social Sciences Veterinary Other

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DETERMINASI PEMBERIAN MINYAK TRANS TERHADAP STRES OKSIDATIF PADA TIKUS GALUR WISTAR DENGAN MALONDIALDEHIDA PANKREAS SEBAGAI INDIKATOR Mawali, Maharja; Santoso, Koekoeh; Kusumorini, Nastiti; Satyaningtijas, Aryani Sismin; Supiyani, Atin
Bioma Vol. 11 No. 2 (2015): Bioma
Publisher : LPPM Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (454.681 KB) | DOI: 10.21009/Bioma11(2).10

Abstract

ABSTRACT Trans fatty acids (TFAs) are the entire unsaturated fatty acids containing one or more double bonds isolated in trans configuration believed as predisposing factor of oxidative stress, excluding conjugated double bond fatty acids. Malondialdehyde (MDA) is a product of lipid peroxidation used as oxidative stress marker. The objective of this study was to see the correlation between TFAs containing-oil (consists of 3-6% TFAs) intake at various administration doses and pancreatic MDA levels in Wistar rats. Twelve rats were grouped according to administration doses (20%, 40%, 60% of given feed total energy and control group). TFAs containing-oil was administered orally once a day for 70 days at given doses by force feeding. Pancreatic MDA were measured using TBARS assay adapted from Singh et al. (2006). Increase of TFAs containing-oil administration dose caused insignificant increase of pancreatic MDA level. Keywords: trans fatty acids, oxidative stress, malondialdehyde, Wistar rats, palm oil
DETERMINASI PEMBERIAN SUKROSA TERHADAP KADAR SGPT DAN SGOT TIKUS GALUR WISTAR SEBAGAI INDIKATOR FUNGSI HATI: Determination of High Sucrose Intake to SGPT and SGOT Concentration in Wistar Rats As Indicator of Liver Function. Andayani, Prawita Lintang; Santoso, Koekoeh; Kusumorini, Nastiti; Satyaningtijas, Aryani Sismin; Supiyani, Atin
Bioma Vol. 12 No. 1 (2016): Bioma
Publisher : LPPM Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (453.448 KB) | DOI: 10.21009/Bioma12(1).8

Abstract

The aim of the study was to determine the correlation between sucrose intake at various administration doses to SGPT and SGOT level in Wistar rats. SGPT and SGOT level in blood serum were used as parameter of liver function. Twelve rats were grouped according to administration doses (20%, 40%, 60% of given feed total energy and control group). Sucrose was administered orally once a day for 70 days at given doses by force feeding. SGPT dan SGOT level were measured using SGPT and SGOT Test Kit and read using spectrophotometer. The result indicated that increased administration dose caused a significant increase of SGPT and SGOT level.
RESPON AKTIVITAS TIKUS WISTAR JANTAN AKIBAT KONDISI DIET TINGGI SUKROSA DIUKUR MENGGUNAKAN PEREKAM AKTIVITAS: Activities Response Measurement on Male Wistar Rats With High Sucrose Diet Using Activity monitoring device Wijaya, Yanuar Restu; Santoso, Koekoeh; Isdoni, Isdoni; Supiyani, Atin
Bioma Vol. 12 No. 2 (2016): Bioma
Publisher : LPPM Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (412.797 KB) | DOI: 10.21009/Bioma12(2).5

Abstract

Excessive energi consumption play a role in increasing blood glucose levels (hyperglycemia), due to the inability of the hormone insulin to compensate the high blood glucose levels. Blood glucose receptor found in the hypothalamus of VMH (Ventro Medial Hypothalamus) and LH (the Lateral Hypothalamus) is able to detect and change the settings for the feeding activity. The aim of this study was to obtain the relationship between high sucrose feeding on male Wistar rats of behavior and activity. This method uses Wistar rats (Rattus norvegicus) as an animal model. Sixteen rats were grouped into 4 treatment groups. The first group was given additional feed 20% sucrose, the second group was given additional feed 40% sucrose, a third group was given additional feed 60% sucrose, and the last as a control group. This feed given continuously for 70 days.Observation of activities conducted using Opto-varimex® auto-track system ver.4.31. The results showed an corellation between activity based doses of sucrose.
PENGARUH SUHU TERHADAP DIFERENSIAL LEUKOSIT SERTA KADAR MALONDIALDEHIDE (MDA) BURUNG PUYUH (Coturnix coturnix Japonica) Maheshwari, Hera; Sasmita, Annissa Nuridfi; Farajallah, Achmad; Achmadi, Pudji; Santoso, Koekoeh
Bioma Vol. 13 No. 2 (2017): Bioma
Publisher : LPPM Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (506.533 KB) | DOI: 10.21009/Bioma13(2).4

Abstract

The main problem in tropical poultry farming that often happens is a high mortality rate. Deaths occurrance mostly by heat stress, a condition which is caused by high temperature ( > 28 ° C). Prolonged heat stress was given to 24 quails grouped in four groups: A (39 ° C), B (41 ° C), C (43 ° C) and D (45 ° C). Provision of heat stress was done when the quails were 2 days old. Blood sampling was performed at the age of 6 weeks. Overall, there was an increase in the number of white blood cell, heterophile, eosinophil, monocyte, the ratio between heterophyll and lymphocyte and malondialdehyde (MDA) levels in all treatment groups. While the number of lymphocytes decreased in all treatment groups. Basophils had a significant increase in group C, but there was a decrease in group B and D decreased from control. This indicates that maintenance above temperature > 25 ° C can cause oxidative stress due to heat stress in quail.
LITERATUR REVIEW: PENGARUH INJEKSI INTRACEREBROVENTRIKULAR STREPTOZOTOCIN PADA OTAK MENCIT SEBAGAI KANDIDAT HEWAN MODEL ALZHEIMER Daryanti, Edhita Putri; Anggadiredja, Kusnandar; Wibowo, Agung Eru; Santoso, Koekoeh
PROSIDING SEMINAR KIMIA Vol 3 No 2 (2025): Prosiding SNKT 2024
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Abstract

Background: Animal models of Alzheimer's have now been developed in various studies to become potential animal models suitable for clinical conditions. Alzheimer's in clinical conditions is characterized by Amyloid βeta (Aβ) plaques and intracellular tangles of neurofibrillary tangles as well as disorders of the acetylcholinesterase enzyme in the hippocampus. Rodents used include rats and mice. Mice are used because they are efficient and parts of the brain can be penetrated with a needle without requiring surgery. Objectives: Appropriate toxicant induction is needed so that the process of developing Alzheimer's pathology is known, namely the use of Streptozotocin. Intracerebroventricular induction of strepzotocin in mice needs to be further understood. Material and Methods: The research method uses literature review with identification, screening, evaluation and interpretation of all research results collected through online search engines such as; Sciencedirect, Pubmed, GoogleScholar with keywords and meet the inclusion criteria Results: The results of the synthesis obtained selected data from 8 articles. ICV-STZ has been proven from various studies to induce Alzheimer's pathology in both young and old male mice through neuroinflammatory pathways, oxidative stress, increasing Aβ expression and hyperphosphorylation of Tau as Alzheimer's markers which are similar to clinical patients. Keywords : Alzheimer, Hewan model, Literatur review, Mencit, Streptozotocin.
PHYSICO-CHEMICAL VALUE AND HYPOGLYCEMIC EFFECT OF INDUSTRIAL-GRADE ETHANOLIC EXTRACT OF PIGEON PEA (Cajanus cajan) LEAVES AND GINGER (Zingiber officinale var. amarum) Wresdiyati, Tutik; Alfarisi, Hamzah; Putri, Anisya Saeila; Abidah, Puri Adzrok; Darawati, Made; Aziz, Sandra; Sadiah, Siti; Astawan, Made; Santoso, Koekoeh
Jurnal Kedokteran Hewan Vol 18, No 1 (2024): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v18i1.31691

Abstract

This study aimed to analyze flavonoid and 6-gingerol content and to test the hypoglycemic effects of industrial-grade Cajanus cajan (pigeon pea) leaf and Zingiber officinale rhizome (ginger) extracts on hyperglycemic rats. Extraction utilized maceration with 70% alcohol at PT. Insular Multi Natural. Extracts were characterized and analyzed for flavonoids and 6-gingerol content. Hypoglycemic activity was assessed using the oral glucose tolerance test (OGTT) on rats with induced hyperglycemia via 90% sucrose solution. The results indicated higher flavonoid content in C. cajan leaf extract (4090.09338.23 mg/100 g) compared to Z. officinale extract (622.74203.39 mg/100 g), while gingerol content in Z. officinale extract was 701.524.42 mg/100 g. This study concluded that combination of industrial-grade pigeon pea leaves extract and ginger extract reduce the level of blood glucose in hyperglycemic model rats at all combination dose (150:150, 200:100, and 100:200 mg/kg BW). The combination dose of 200:100 mg/kg BW showed the best blood glucose level profile.
Pemberian Ekstrak Daun Singkong pada Burung Puyuh yang Mengalami Cekaman Panas Santoso, Koekoeh; Maria, Joanita; Ika Mayasari, Ni Luh Putu; Jumadin, La
Jurnal Sain Veteriner Vol 42, No 1 (2024): April
Publisher : Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.73585

Abstract

Fenomena iklim tropis, ekuinoks, dan pemanasan global di Indonesia dapat menyebabkan masalah cekaman panas pada peternakan unggas termasuk puyuh. Dampaknya adalah penurunan performa dan produksi puyuh, oleh karena itu perlu dilakukan upaya untuk mengatasi masalah heat stress. Tujuan dari penelitian ini adalah untuk membuktikan potensi ekstrak daun singkong untuk mengatasi cekaman panas pada puyuh dewasa anas. Penelitian dilakukan dengan menggunakan 16 ekor puyuh yang dibagi menjadi 4 kelompok, terdiri dari 4 ekor puyuh sebagai kontrol yang diberi perlakuan suhu 35 °C, dan masing-masing 4 ekor puyuh lainnya diberi perlakuan suhu 35 °C dan diberi ekstrak daun singkong dengan dosis yang berbeda-beda sebesar 5,292 mg/168g, 10,584 mg/168 g, dan 21,168 mg/168 g berat badan. Hasil penelitian menunjukkan bahwa ekstrak daun singkong yang mengandung flavonoid dan klorofil terbukti dapat menurunkan kadar malondialdehida (MDA) pada puyuh yang mengalami cekaman panas. Kualitas telur juga meningkat berdasarkan parameter tinggi albumin, tinggi kuning telur, dan tebal cangkang, namun kadarnya tidak signifikan. Parameter total leukosit, rasio heterofil per limfosit, dan diferensial leukosit tidak menunjukkan perbedaan yang signifikan. Ekstrak daun singkong juga belum terbukti mampu menurunkan total protein pada puyuh yang mengalami cekaman panas. Hasil vaksinasi ND inaktif yang dilakukan satu kali menunjukkan titer antibodi yang rendah pada semua kelompok.
Edukasi Praktik Pemberian Makanan MP-ASI sebagai Upaya Pencegahan Stunting pada Anak di Bontang Kuala, Kalimantan Timur Hapsari, Afrilia Bagus Putri; Cintiyah, Farida; Khairina, Amalia; Simanjuntak, Saut Renato Rahmat; Rachmani, Ratasha Zahwanda; Noor, Muhammad Primadevan Pascaharchana; Fauziah, Kholidah; Simanjuntak, Imelda Yanti Lumongga; Mutaqqin, M. Ichwan; Santoso, Koekoeh
Jurnal Pusat Inovasi Masyarakat Vol. 4 No. 2 (2022): Oktober 2022
Publisher : Direktorat Pengembangan Masyarakat Agromaritim, Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jpim.4.2.13-22

Abstract

Stunting ialah bagian dari kondisi gizi kronis yang disebabkan oleh kekurangan asupan zat gizi dalam jangka panjang akibat asupan makanan yang tidak mencukupi untuk memenuhi gizi optimal. Pengumpulan data dalam survei ini dilakukan secara tatap muka dengan masyarakat yang tinggal di Bontang Kuala, Provinsi Bontang Utara, yang juga merupakan tujuan dari survei ini. Metode yang diterapkan adalah identifikasi pola masyarakat berdasarkan analisis deskriptif yang didapat dari persepsi masyarakat dan permasalahan yang mempengaruhi stunting. Banyak keluhan masyarakat Bontang Kuala tentang balita dan bayi yang masih menangis setelah disusui. Hal ini dapat terjadi karena balita dan bayi tidak merasa kenyang setelah disusui dan asupan makanan yang diberikan tidak mencukupi. Untuk itu kelompok KKN-T telah memberikan materi tentang MP-ASI. Kegiatan KKN-T IPB di Kelurahan Bontang Kuala telah berjalan sesuai harapan, berkat kerjasama peserta KKN-T IPB, Kelurahan Bontang Kuala, kelompok PKK dan masyarakat berdasarkan analisis sosial budaya dengan analisis deskriptif.
Profil eritrosit, hemoglobin, dan nilai hematokrit luwak Jawa (Paradoxurus hemaphroditus) pemakan dan tidak pemakan buah kopi Elsi Rahmadhani; I Wayan Teguh Wibawan; Damiana Rita Ekastuti; Ronald Tarigan; Pudji Achmadi; Isdoni Isdoni; Koekoeh Santoso; Aryani Satyaningtijas
ARSHI Veterinary Letters Vol. 7 No. 1 (2023): ARSHI Veterinary Letters - Februari 2023
Publisher : School of Veterinary Medicine and Biomedical Sciences, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avl.7.1.15-16

Abstract

Luwak Jawa (Paradoxurus hemaphroditus) merupakan hewan yang memiliki kemampuan menghasilkan biji kopi yang berkualitas, sehingga status kesehatannya perlu untuk diperhatikan. Gambaran darah dapat dijadikan sebagai indikator status kesehatan luwak pada kondisi tertentu. Penelitian mengenai luwak telah banyak dilaporkan, namun belum ada penelitian mengenai parameter fisiologis khususnya profil eritrosit dari luwak yang sengaja diberikan buah kopi secara terus menerus selama 3 bulan. Penelitian ini bertujuan untuk menghitung profil eritrosit pada luwak Jawa pemakan pemakan kopi dan tidak pemakan buah kopi. Gambaran darah luwak Jawa pada saat adaptasi dan pemeliharaan berfluktuasi. Rataan jumlah eritrosit luwak pemakan buah kopi dan tidak pemakan buah kopi adalah (8,24±2,40) x 106/mL dan (8,25±2,16) x 106/mL, kadar hemoglobin adalah (6,18±2,21) g/dL dan (6,40±2,21) g/dL dan nilai hematokrit adalah (16,50±2,21) % dan (16,00±2,14) %. Secara umum gambaran darah luwak Jawa pemakan buah kopi memiliki rataan yang lebih rendah dari pada luwak Jawa yang tidak diberi buah kopi.
Pemendekan waktu siklus estrus pada luwak Jawa (Paradoxurus hermaphroditus) terdeteksi melalui metode ulas vagina Nelda Fliza Zora; Mokhamad Fakhrul Ulum; Damiana Rita Ekastuti; Ronald Tarigan; Pudji Achmadi; Isdoni Bustaman; Koekoeh Santoso; Hera Maheshwari; Agik Suprayogi; Wasmen Manalu; Aryani Satyaningtijas
ARSHI Veterinary Letters Vol. 7 No. 2 (2023): ARSHI Veterinary Letters - Mei 2023
Publisher : School of Veterinary Medicine and Biomedical Sciences, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avl.7.2.35-36

Abstract

Luwak Jawa (Paradoxurus hermaphroditus) merupakan salah satu hewan liar yang dapat dimanfaatkan sebagai penyeleksi biji kopi untuk menghasilkan kopi berkualitas dan bernilai ekonomis tinggi. Pemeliharaan yang tidak sesuai dapat memengaruhi kondisi fisiologis dan reproduksi luwak sehingga penting untuk diketahui sebagai dasar manajemen pemeliharaan dan kesehatan untuk optimalisasi produksi, pencegahan penyakit, dan konservasi luwak. Pemantauan ini bertujuan untuk mengetahui panjang waktu total siklus estrus dan waktu dari setiap fase estrus yaitu fase proestrus, estrus, metestrus dan diestrus. Luwak Jawa dari diperoleh dari pasar hewan sebanyak 2 ekor berjenis kelamin betina dengan bobot badan sekitar 4 kg diambil data ulas vagina selama 21 hari pada pagi dan sore hari. Sel epitel vagina diperiksa di bawah mikroskop dan dianalisa secara kuantitatif. Hasil pengamatan menunjukkan pemendekan siklus estrus dengan panjang total siklus estrus yaitu 121,5±7,5 jam (5 hari). Durasi waktu proestrus 12,0±0,0 jam, estrus 22,5±3,0 jam, metestrus 25,5±3,0 jam dan diestrus 61,5±3,0 jam.
Co-Authors A.S. Satyaningtijas Abdul Zahid Abidah, Puri Adzrok ACHMAD FARAJALLAH Afiff , Usamah Agik Suprayogi Agung Eru Wibowo Agus Wijaya Ainul Khadija Saleema Akhiruddin Maddu Aldo Febriano Tarigan Alfarisi, Hamzah Amrozi Andayani, Prawita Lintang Anindita Sista Widyadhari Anindita Sista Widyadhari Annisa Madyanti Geminastiti Parampasi Ardilasunu Wicaksono Aryani Satyaningtijas Asah Hilaliah Athirah Rerana Fitrianthy Aziz, Sandra Cintiyah, Farida Dalia Sukmawati Damhuri Damhuri Damiana Rita Ekastuti Daryanti, Edhita Putri David Anwar Denny Widaya Lukman Denny Widya Hikman Desrayni Hanadhita Dhani S. Wibawa Dwi Nurhidayah Zubaidah Edi Sukmawinata Edi Sukmawinata Elok Budi Retnani Elsi Rahmadhani Etih Sudarnika Fauziah, Kholidah Hadri Latif Hapsari, Afrilia Bagus Putri heny Nitbani HERA MAHESHWARI Herwin Pisestyani Huda Shalahudin Darusman I wayan Teguh Wibawan Ika Mayasari, Ni Luh Putu ikhwan wirahadikesuma Ikhwan Wirahadikesuma Ira Agustina Dewi Gandasari Irwan Oktoni Isdoni Bustaman Isnaeni Isnaeni Isnaeni Jefri Naldi Jumadin, La Jumardin jumardin jumardin Khairina, Amalia Komariah komariah komariah Kudang Boro Seminar Kusnandar Anggadiredja La Jumadin La Jumadin La Jumadin La Jumadin Lili Darlian Lili Darlian MADE ASTAWAN Made Darawati Maharani Salsabila Mahendra, Arindina Maria, Joanita Maryce Agusthinus Walukou Mawali, Maharja Mokhamad Fakhrul Ulum, Mokhamad MUHAMMAD AGIL Mutaqqin, M. Ichwan Nadhear Nadadyanha Dannar NASTITI KUSUMORINI Nelda Fliza Zora Nenis Rahma Wulandari Niken Ulupi Noor, Muhammad Primadevan Pascaharchana Nugraha, Arifin Budiman Nuri Ardiani Nurul Masyita, Nurul Okta Irviana Muminin Okti Nadia Poetri Pudji Achmadi Putri, Anisya Saeila Rachmani, Ratasha Zahwanda Rani Audona Rasyida Ulfa Ridi Arif Ridzky Pratama Risqika Akla Velayati Rivangga Yuda Hendika Ronald Tarigan Rotinsulu, Dordia Anindita Sadiah, Siti Sasmita, Annissa Nuridfi Simanjuntak, Imelda Yanti Lumongga Simanjuntak, Saut Renato Rahmat sri murtini . Supiyani, Atin Tarigan, Ronald Tutik Wresdiyati Ulfatin Khoiriyah Herowati Warysatul Ummah Wasmen Manalu Wijaya, Yanuar Restu Yulvian Sani Yusuf Ridwan Zulvia Maika