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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Biology, Medicine, & Natural Product Chemistry Biomedika Bioeksperimen: Jurnal Penelitian Biologi Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) Majalah Kesehatan FKUB Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Herb-Medicine Journal MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Surya Medika: Jurnal Ilmiah Ilmu Keperawatan dan Ilmu Kesehatan Masyarakat Medfarm: Jurnal Farmasi dan Kesehatan Open Access Indonesian Journal of Medical Reviews Gemakes: Jurnal Pengabdian Kepada Masyarakat Proceeding ISETH (International Summit on Science, Technology, and Humanity) Prosiding University Research Colloquium Jurnal Pengabdian Masyarakat Medika Biomedika
Riandini Aisyah
Universitas Muhammadiyah Surakarta
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Biomedika

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Potential of Natural Larvicide Microemulsion Based on Pomegranate Peel Extract (Punica granatum L) against Dengue Haemorrhagic Fever Vectors Wahyuni, Sri; Aisyah, Riandini; Bestari, Rochmadina Suci; Ryanuranti , Rahma Ghaida; Anggreheni, Putri Dwi
Biomedika Vol 17, No 1 (2025): Biomedika Februari 2025
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v17i1.6696

Abstract

Background: Dengue fever, caused by the dengue virus which is transmitted by the Aedes aegypti mosquito, is a significant global health problem. Controlling the Aedes aegypti vector is key in efforts to reduce the spread of this disease. However, the use of chemical larvicides in vector control has raised concerns regarding environmental impacts and mosquito resistance. Therefore, research related to the development of natural larvicides based on pomegranate peel extract contain flavonoids, terpenoids, tannins, steroids, and saponins, in microemulsion form has an urgency to provide a safer and more sustainable alternative. Objective: To determine the larvicidal activity of microemulsion ethanol extract of pomegranate peel (Punica granatum) against Aedes Aegypti larvae. Methods: This research uses an experimental study design, post-test only controlled group design. The samples used were Aedes aegypti larvae instar III-IV. There were 12 treatment groups consisting of positive control, negative control, and treatment groups with microemulsion ethanol extract and ethyl acetate fraction of pomegranate peel extract, each with five different concentrations. Results: The probit analysis results indicate that the LC50 (Lethal Concentration for 50% mortality) for the ethanol extract microemulsion of pomegranate peel is 51,607 ppm, while the LC50 for the ethyl acetate fraction microemulsion of pomegranate peel is 52,401 ppm against Aedes aegypti larvae. Conclusion: the probit analysis shows that the ethanol extract microemulsion of pomegranate peel is slightly more effective in killing Aedes aegypti larvae compared to the ethyl acetate fraction microemulsion. These results emphasize the potential of pomegranate peel extracts as natural larvicides, contributing to sustainable and environmentally friendly mosquito control measures.  
Co-Authors Abd Ghani, Mohd Faiz Ahmad Alrizaldi Alfajri, Asri Anam, Ilham Hafizha Maulana Angesti Atiqah Ranasatri Anggitaratri, Zakia Novi Anggreheni, Putri Dwi Anika Candrasari Anindita Putri Handayani Ariffah, Hilda Zaniba Arrohma, Farah Aryanto Asfarina, Fatin Ayyasi, Quanta Azenta, Moch. Tabriz Bestari, Rochmadina Brilliantama, Fandy Akbar Devi Usdiana Rosyidah Dwi Advina Herdiyanti Dyah Farida Inli Em Sutrisna Erika Diana Risanti Estu Puguh Prabancono Faatiha, Arsyal Wanda Fauzi, Favian Fauzi, Favian Arriella Shabri Ikmal Fikri, Muhammad Ihsanul Fitri, Alifah Aulia Graffico Eryza Oldiara Gunawan, Ryan Budi Haliza, Sheli Nur Handayani, Anindita Putri Herdiyanti, Dwi Advina Hidayah Karuniawati Hidayatullah, Muhammad Alim Abdul Majid Iin Novita Nurhidayati Mahmuda Indra Nuroso Jatmiko, Safari Kamila, Aulida Azkia Kumala, Aswa Arsa Kurniati, Yuni Prestyo Lestari, Nining Listiana Masyita Dewi Mapa, Anna Rochim Maulida Rahmah, Maulida Maulida, Amira Hasna Maylafaiza, Annisa Mitoriana Porusia Muhamad Irfan Hidayatullah Muhammad Adha Muhammad Alim Abdul Majid Hidayatullah Nafisa, Balqis Najmii, Muhammad Firoos Allaam Noor Hafida Widyastuti Nordin, Noraziah Novita, Iin Nur Mahmudah Nur Mahmudah Nurhaliza, Sheli Nurhayani Nurhayani nurhayani Nurhayani, N Nuroso, Indra Pambudi, Nasrurrofiq Risvana Bayu Peni Indrayudha Prabancono, Estu Puguh Prabowo, Nurhasan Agung Pratama, Nur Puspitasari, Metana Rahayu, Destri Ramadhani, Marsyanda Ratnasari Bondan Wijayanti Reisya Tiara Kandita Reisya Tiara Kandita, Reisya Tiara Retno Sintowati - Rif'aini, Fidhia Nur Rochmadina Suci Bestari Rohman, Raihan Fadzlur Rohmaniar, Delianti Roslan, Nuruliza Ryan Budi Gunawan Ryanuranti , Rahma Ghaida Safari Wahyu Jatmiko Salsabila, Nabila Mutia Sella Felina Setiani, Hilda Sholeh, Muhammad Dzikru Irfan Sri Wahyuni Sri Wahyuni Sukardi, Nadya Sulistiyo, Azka Hafiy Sulistyo, Ayu Indah Supraba, Intan Pratiwi Suryani, Latifah Syahida, Safira Tara , Irmanawati Audhina Nirmala Tolibin, Restu Triwulandani Tri Agustina, Tri tri wahyuni Usdiana Rosyidah, Devi Utami, Aurelia Ratna Utami, Indari Wafiq, Muhammad Azzim Wahyu Jatmiko, Safari Wibowo, Haryo Kunto Wijayanti, Ratnasari Bondan Wulandari Berliani Putri Wulandari Berliani Putri, Wulandari Berliani