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Journal : Gunung Djati Conference Series

MONYET EKOR PANJANG (Macaca fascicularis) SEBAGAI HEWAN MODEL DAN ETIKA PENGGUNAANNYA Ratni Ernita; Tatang Mitra Setia; Fitriya Nur Annisa Dewi; Huda Shalahudin Darusman
Gunung Djati Conference Series Vol. 6 (2021): Seminar Nasional Biologi (SEMABIO) 6 Tahun 2021
Publisher : UIN Sunan Gunung Djati Bandung

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Abstract

The use of nonhuman primates as animal models in biomedical research has an important role in the development of human health. A close phylogenetic relationship with humans as well as similarities in genetics, behavior and biochemical activities are some of the things that underlie the selection of nonhuman primates as animal models. Cynomolgus macaques (Macaca fascicularis) is one of Indonesia's endemic primates which is widely used in research. Its current status as Appendix II in Convention International Trade in Endangered Species of Wild Fauna and Flora (CITES) defines that the population remains quite large in nature, which allows this species to be used in research, as long as they are sourced from the captive-bred population. Although the use of nonhuman primates in research is unavoidable, it is warranted that potential harm such as distress, discomfort, stress, pain and even death have to be avoided or minimized. Implementation of ethics is therefore required for the care and use of cynomolgus macaques in research, such as by assuring that the 3R principles (replacement, reduction, refinement) are met. Refinement can be achieved by applying the principles of animal welfare known as the Five Freedoms of Animal Welfare (5F). The active implementation of these ethical principles continues to develop along with the development of science and technology, and receives more spotlight in the world of biomedical research globally. Ensuring adequate implementation of ethical principles in research with nonhuman primates in each research institution must be under the oversight of an IACUC (Institutional Animal Care and Use Committee), which will weigh on the harm to animals compared to the benefits to humans. Active implementation of the principles of ethics and animal welfare will result in increasing the quality of research, serves as an assurance to the society, and in compliance to the requirements for good scientific publication.
Co-Authors A.S. Satyaningtijas Achmad, Yusuf Farid Adi Winarto Adi Winarto Agik Suprayogi Ahmad Kamal Nasution Ahmad Subhan Ai Hertati, Ai Akhiruddin Maddu Andhika Yudha Prawira Andi Hiroyuki Angela Mariana Lusiastuti Anita Esfandiari Annisa Dewi, Fitriya Nur Apon Zaenal Mustopa Aprilyana, Lia Ardiansyah Nurdin Benvika Chairunnisa, Sheila Damiana Rita Ekastuti Dayana, Hepy Dewi Ratih Agungpriyono Dewi, Fitriya Nur Annisa Dondin Sajuthi DYAH PERWITASARI -FARAJALLAH Ekawati, Nurlaili Ekowati Handharyani Elok Budi Retnani Entang Iskandar Entang Iskandar Entang Iskandar Entang Iskandar Ernes Andhesfa Etih Sudarnika Fadla, Ilma Nadya Fauzi Abdurrahman Munggaran Femke Den Haas Ferdinandez, Mariana Firdaus, Moh Egy Rahman Fitri, Arni Diana Habib Ilham Maulana Al Adhim Hana Intishar Sawitri Hardo Basuki Harrold Halilintar MR Subu Taopan Hasya, Karin katina HERA MAHESHWARI Hidayaturrahmah Hidayaturrahmah I wayan Teguh Wibawan Ice Lusia Marta IETJE WIENTARSIH Ikramullah, Muh. Chaeril Indra Bachtiar Indra Bachtiar Indriawati, Iin Iqbal Ngabdusani Irawan, Herman Irawan, Shasmita Irma Herawati Suparto Jendri Mamangkey Joko Pamungkas Jusak Nugraha Kanti Rahmi Fauziyah Katrin Roosita koekoeh santoso Krisnayanti, Ni Putu Eka Lina Elfita Lina Elfita Linda Tjhin Lis Rosmanah Loe, Fhady Risckhy Loes (ML) Schure Maria Fatima Palupi Maria Fatima Palupi Maria Fatima Palupi Megawati Iskandar Mia Audina Muhammad Hamdan Mustopa, Apon Z. Ningrum, Emilna Mega Novi Mayasari Noviana, Rachmitasari Novianti, Ela Novriyandi Hanif Nugroho, Setyo Widi Nurfatwa, Maritsa Perdhana, Ika Satya Permanawati Permanawati PERMANAWATI, PERMANAWATI Puji Rianti Putri, Indah Aprianti Rachmitasari Noviana Rahmania Hanim Rahminiwati, Min Randall C. Kyes Rasyida Ulfa Ratna, Lita Tri Ratni Ernita Ratu, Safira Pinaka Pramestika Raymond R. Tjandrawinata Ridzki M.F. Binol Rifqiyah Nur Umami, Rifqiyah Nur Rika Sudranto Rizal, Muhammad Farid Rizki Aulia Ansari Roostita L Balia Rosmanah, Lis Rosyid, Bahaudien Sari, Isti Kartika Savitri Novelina Sela Septima Mariya Setyawaty, Dyah Setyo Widi Nugroho Sibit, Denniswara SILMI MARIYA Silmi Mariya Silmi Mariya Silvy Thiyana Soedarso, Yovi Alwi Sony Hartono Wijaya Sri Wahyuni Srihadi Agungpriyono Subu Taopan, Harrold Halilintar MR Suduri, Adam Sukenda Sukenda Sumitro - Sundari, Betty Suparto, Irma H. SURYA, MARYATI Suryo Saputro Tambunan, Anggitha Tatang Mitra Setia Tatik Mufidah Tommy Langgeng Abimanyu Tri Wibawa UUS SAEPULOH Uus Saepuloh Uus Saepuloh Vinka Aftinata Kusumaputri Wartika Rosa Farida Wasmen Manalu WIDANARNI WIDANARNI Wira, Dwi Wahyuda Yuliana Yuliana Yuliana Zaelani, Bella Fatima Dora