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All Journal UNEJ e-Proceeding JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Dinamika Pengabdian (JDP) Universa Medicina Journal of Islamic Medicine CARADDE: Jurnal Pengabdian Kepada Masyarakat PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat JFIOnline Community Development Journal Indian Journal of Forensic Medicine & Toxicology Humanism : Jurnal Pengabdian Masyarakat Berkala Ilmiah Kimia Farmasi Berkala Penelitian Hayati Jurnal Masyarakat Madani Indonesia Indonesian Journal of Pharmacy and Natural Product Media Farmasi
Idha Kusumawati
Fakultas Farmasi Universitas Airlangga
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Journal : JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA

 1 
Aphrodisiac Activity of Ethanolic Extracts from the Fruits of Three Pepper Plants from Piperaceae Family Idha Kusumawati; Syailendra Mahatmaputra; Rohman Hadi; Rohmania Rohmania; Subhan Rullyansyah; Helmy Yusuf; Abdul Rahman
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 8 No. 2 (2021): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v8i22021.194-199

Abstract

Background: Pepper plants belong to the Piperaceae family with many pharmacological activities. The fruits of these plants have been widely used traditionally for various therapies, one of which is an aphrodisiac. Objective: The purpose of this study was to determine the aphrodisiac activity of the fruits of three pepper plants, Piper nigrum, Piper retrofractum, and Piper cubeba to prove their traditional use. Methods: The level of piperin, the active compound of plants from the family Piperaceae, was also determined in the ethanolic extract of those three fruits of the pepper plant. The aphrodisiac activity was determined by counting the number of introducing and mounting mice. The acute toxicity test of the extract was carried out according to the OECD-423 guidelines. Results: The ethanolic extract of Piper nigrum fruits had the highest piperin concentration, while the ethanolic extract of Piper retrofractum fruits had the highest aphrodisiac activity, according to the findings. During the entire duration of the acute toxicity study, no signs of toxicity or mortality were discovered.Conclusion: This study proves that all fruits of three species of pepper plants exhibit aphrodisiac activity. Furthermore, this study also shows that not only piperin is responsible for the aphrodisiac effect.
Growth Inhibitory Effects of Red and Yellow Passion Fruits against MRSA and ESBL-producing Bacteria Aprelita Nurelli Dwiana; Achmad Toto Poernomo; Iif Hanifa Nurrosyidah; Isnaeni; Dian Rahmawaty; Idha Kusumawati
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 10 No. 1 (2023): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v10i12023.86-91

Abstract

Background: Red passion fruit (Passiflora edulis Sims) and yellow passion fruit (Passiflora edulis f. flavicarpa) are native Indonesian fruits with numerous health benefits. This study used de Man, Rogosa, and Sharpe (MRS) medium for fermentation. Probiotics are beneficial microorganisms obtained from fermented food or drink (Hamid et al., 2020). Probiotics and lactic acid bacteria, which are known to have various benefits, particularly as antibacterial, are among the active components identified in passion fruit pulp. Objective: This study examinedthe antibacterial activity of red and yellow passion fruits. Methods: Freshly collected passion fruit pulps were fermented in MRS medium in a shaker incubator for 48 hours at 24°C. The filtrates from the fermented broth were tested against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA) and extended-spectrum beta-lactamase (ESBL)-producing bacteria. The analyses applied the streak plate method and the total plate count method. Results: The Minimum Inhibitory Concentrations (MICs) of red passion fruit ferment filtrate against MRSA 10 and MRSA 11 were 50% and 60%, respectively, and of yellow passion fruit ferment filtrate against MRSA 10 and MRSA 11 were both 30%. Meanwhile, the MICs of red passion fruit ferment filtrates were 35% against ESBL 41 and ESBL 43 and 25% against ESBL 45 and ESBL 47, whereas the MICs of yellow passion fruit (Passiflora edulis f. favicarpa) ferment filtrates were 25% against ESBL 41 and ESBL 43, and 12.5% against ESBL 45 and ESBL 47. Red passion fruit (Passiflora edulis Sims) and yellow passion fruit (Passiflora edulis f. flavicarpa) ferment filtrates became growth inhibitors against the clinical isolates of MRSA and ESBL-producing bacteria with an optimal fermentation time of 24 hours and an optimal concentration of 75%. Conclusion: The results of this study found that the fermented filtrates of red and yellow passion fruits in MRS media could be developed as an antibacterial against MRSA and ESBL-producing bacteria.
Comparative Study of Densitometry and Videodensitometry for Quantitating the Active Pharmaceutical Ingredients Using Thin Layer Chromatography – Systematic Review Firmansyah Ardian Ramadhani; Idha Kusumawati; Riesta Primaharinastiti; Subhan Rullyansyah; Fajar Jamaluddin Sandhori; Hanif Rifqi Prasetyawan
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 10 No. 2 (2023): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v10i22023.141-150

Abstract

Background: Chromatography is one of the analytical techniques widely used for the quality control process in the pharmaceutical industry. One of the analytical methods used in drug analysis is Thin Layer Chromatography (TLC). The analysis process of TLC can be performed using densitometry (scanner) or videodensitometry (videoscan). The principal analysis of densitometry (scanner) is based on the density measured from each spot on the TLC plate using a specific wavelength range, and videodensitometry (videoscan) is performed by taking pictures of the plate using a Visualizer at a specific wavelength. Objective: This review article discusses the application of densitometry and videodensitometry methods for quantitative analysis of pharmaceutical products. Methods: This study was conducted using a systematic review method using the PRISMA statement from January to April 2023. Four databases were searched: PubMed, ScienceDirect, Scopus, and Google Scholar with inclusion criteria: studies on thin layer chromatography analysis using densitometry and videodensitometry. Results: Based on the ten articles in this study, it is known that the active ingredient concentrations in pharmaceutical products can be determined using densitometry and videodensitometry. The statistical analysis results show no significant difference between the two methods' chemical concentrations of active ingredients in pharmaceutical products. Conclusion: TLC densitometry and videodensitometry is a valid methods analysis that can be used for quantitating the active pharmaceutical ingredient concentration in finished pharmaceutical products.
Effect of Integrated TOGA-Nutrition Education on Stunting Prevention Knowledge among Health Volunteers and Adolescents in Lamongan, Indonesia: A Pre-Post Intervention Study Kusumawati, Idha; Puspitasari, Hanni Prihhastuti; Soesilawati, Pratiwi; Izzah, Zamrotul; Fitria, Anisa Lailatul; Ramadhani, Firmansyah Ardian; Rullyansyah, Subhan; Pratama, Yusuf Alif; Pattymahu, Charlyna Veronika Puspitasari; Gamar, Fahmi Haitsami Ibnu; Ruzainah Ali
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 12 No. 3 (2025): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v12i32025.342-354

Abstract

Background: Lamongan, Indonesia, is facing a significant public health issue, with high rates of stunting (27.5% in 2022) and adolescent anemia (60.0% in Babat district). A significant knowledge gap exists in the community, particularly regarding the effective use of Family Medicinal Plants (TOGA) for prevention, highlighting the need for structured intervention programs to address these public health issues. This study evaluated an integrated education program designed to improve knowledge and shift perceptions regarding TOGA, assessing differential knowledge gains between health volunteers and adolescents. Methods: This pre-post intervention study involved 54 female participants (27 health volunteers and 27 adolescents) from Kebalanpelang Village, Babat District, Lamongan. All participants received the same 120-minute integrated TOGA-nutrition education based on Social Cognitive Theory, covering stunting prevention, complementary feeding, breastfeeding optimization, and TOGA applications using evidence-based traditional medicinal plants. Knowledge was assessed using the same validated 10-item questionnaire (Cronbach's α=0.81) for both groups, covering three domains: complementary feeding guidelines (3 items), breastfeeding optimization (3 items), and TOGA applications for stunting prevention (4 items), administered before and immediately after the intervention. Results: The intervention was highly effective, yielding a statistically significant 25.4% mean knowledge gain across all participants (3.6±2.1-point gain, p<0.001). Adolescents showed the most dramatic improvement, achieving a 39.7% knowledge increase (a 4.8-point gain). While health volunteers had a more modest gain of 14.7% (a 2.4-point increase), the intervention successfully narrowed the initial knowledge disparity between the two groups by 57% (reducing the gap from Δ4.2 to Δ1.8 points). Domain-specific analysis revealed significant gains across all areas: complementary feeding (+26.8%), breastfeeding (+26.7%), and TOGA applications (+23.9%, all p<0.001). A strong inverse correlation between age and knowledge gain (r=-0.72, p<0.001) indicated that younger participants, particularly those aged 15-17 years, demonstrated superior learning capacity. Conclusions: The implementation of integrated TOGA-nutrition education significantly enhanced stunting prevention knowledge. This intervention is particularly effective for adolescents, which employs role-specific content, successfully mitigates cultural barriers and leads to a measurable reduction in knowledge equity gaps. Strong evidence of participant confirms the program's cultural fit and operational readiness, making a compelling case for its integration and scaling within Indonesia’s broader stunting prevention efforts.
Co-Authors Abdul Rahman Abdul Rahman ACHMAD FUAD Achmad Toto Poernomo Amalia, Savira Rizky Meisya Ana Yuda Anang Teguh Eko Santoso Andi Hermansyah Aprelita Nurelli Dwiana Asri Darmawati Aty Widyawaruyanti Bambang Purwanto Bambang Tri Purwanto Dewanthy, Kyrana Sekar Dewi Isadiartuti Dewi Melani Hariyadi Dian Rahmawaty Diana Nurus S Dini Retnowati Diyah, Nuzul Wahyuning Dwi Setyawan Eka Pramyrtha Hestianah Ekapratista, Belinda Nabilah Esti Hendradi Estu Mahanani Dhilasari Fajar Jamaluddin Sandhori Fauzia Azzahra, Fauzia Fauzia, Alfi Nur Firmansyah Ardian Ramadhani Fitria, Anisa Lailatul Gamar, Fahmi Haitsami Ibnu Gemparing Bayu Wiyoto Hadi Poerwono Haliza, Nabila Nur Handayani, Rosita Hanif Rifqi Prasetyawan Hardiyanti, Merry Hari Basuki Notobroto Hari Setiono Harjono Suko Hermansyah, Andi Herra Studiawan Isnaeni Isnaeni Isnaeni Isnaeni Jusak Nugraha Laksmi, Farika Dyani Laksmi Lucia Tri Suwanti, Lucia Tri Mahalaksmi, Alika Sabrina Marcellino Rudyanto Maria Lucia Ardhani Dwi Lestari Mega Ferdina Suwito Melanny Ika Sulistyowaty Muhammad Agus Syamsur Rijal Munandar, Tristiana Erawati Najlaa, Fatimah Ahla Neni Purwitasari Ni Made Mertaniasih Novian, Farah Kusuma Wardhani Nur Hayati Nurrosyidah, Iif Hanifa Paramita, Diajeng Putri Pattymahu, Charlyna Veronika Puspitasari Pradnyanantha, I Putu Bagus Pramesti, Ragil Putri Prasetyawan, Hanif Rifqi Pratama, Yusuf Alif Pratiwi Soesilawati Primaharinastiti, Riesta Primaharinastiti Purwitasari, Neni Purwitasari, Neny Puspitasari, Hanni Prihastuti Puspitasari, Hanni Prihhastuti Rakhmawati - - Ramadhani, Firmansyah Ardian Rania, Athaya Putri Retno Sari Retno Widyowati Rice Disi Oktarina Riesta Primaharinastiti Riesta Primaharinastiti, Riesta Rohana, Melissa Rohman Hadi Rohmania Rohmania Ruzainah Ali Salam, Anisa Rakhmania Samirah Samirah, Samirah Sandhori, Fajar Jamaluddin Sari Retno Sholika Sari, Trisiyana Siammita, Dhea Anansya Sri Subekti Subhan Rullyansyah Suciati Suciati Suciati Suciati Sudjarwo Sudjarwo Sugiyartono, . Sugiyartono, . Sukardiman Suprapto Maat Suprapto Maat Syailendra Mahatmaputra Tri Widiandani Tristiana Erawati Tutiek Purwanti Tutik Sri Wahyuni Wahjo Djatmiko Wahjo Dyatmiko Wahjo Dyatmiko Wardhana, Brahma Wisnu Kusuma Warsito, Mega Ferdina Wiwied Ekasari Yoes Prijatna Dachlan Yusuf, Helmy Yusuf, Helmy Yuwono Mochamad Zamrotul Izzah