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GAMBARAN HISTOPATOLOGI PARU PADA PASIEN COVID-19: SEBUAH TINJAUAN LITERATUR Hermafasya, Ayu Octarin; Asri, Aswiyanti; Hardisman, Hardisman; Yenita, Yenita; Anggrainy, Fenty; Yulistini, Yulistini
SINERGI : Jurnal Riset Ilmiah Vol. 2 No. 3 (2025): SINERGI : Jurnal Riset Ilmiah, Maret 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v2i3.983

Abstract

COVID-19 was declared a pandemic on March 11, 2020, posing a global challenge for healthcare workers. Understanding the histopathological characteristics of the lungs in COVID-19 patients is crucial for elucidating the disease's pathophysiology. This literature review analyzes pulmonary histopathological findings based on 34 articles retrieved from PubMed, including case reports, case series, and other descriptive studies published between March 2020 and April 2022. A total of 264 patients were examined, the majority of whom were male (184 individuals) with an average age of 64 years. Most patients had comorbidities such as hypertension, cardiovascular disease, diabetes, obesity, and chronic pulmonary disease. Key histopathological findings included hyaline membrane formation, endothelial cell damage, interstitial cell involvement, alveolar and interstitial edema, hemorrhage, microthrombi, and fibrin deposits. These histological patterns suggest diffuse alveolar damage (DAD) in both exudative and proliferative phases, organizing pneumonia (OP), and acute fibrinous organizing pneumonia (AFOP), with varying combinations observed in individual patients.
HUBUNGAN PERILAKU PENCEGAHAN COVID-19 DENGAN TINGKAT STRES PADA MAHASISWA KEPANITERAAN KLINIK PROFESI DOKTER FAKULTAS KEDOKTERANUNIVERSITAS ANDALAS Erika, Niken Ayu Putri; Yaunin, Yaslinda; Isrona, Laila; Yulistini, Yulistini; Ashal, Taufik; Almurdi, Almurdi
SINERGI : Jurnal Riset Ilmiah Vol. 2 No. 5 (2025): SINERGI : Jurnal Riset Ilmiah, Mei 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v2i5.1215

Abstract

The COVID-19 pandemic has affected the clinical learning environment of medical students, who are required to have knowledge, attitudes, and take actions to control COVID-19 infection. The pandemic can be one of the stressors for students undergoing clinical clerkships. Incorrect knowledge, attitudes, and actions can result in infection transmission and cause an increase in stress. The aim of this study was to determine the relationship between knowledge, attitudes, and preventive actions of COVID-19 with the level of stress among medical students undergoing clinical clerkships at the Faculty of Medicine, Andalas University. This study was an analytical research with a cross-sectional approach. The research sample consisted of 246 individuals obtained using cluster random sampling techniques. The research data were in the form of primary data obtained through filling out questionnaires regarding knowledge, attitudes, and preventive actions of COVID-19, and DASS-42. Data analysis used the Spearman rank test with statistical significance determined if p-value < 0.05. Bivariate analysis showed a significant relationship between knowledge, attitudes, and actions with the level of stress with the value of knowledge (p = 0.008, r = -0.168), attitudes (p = 0.045, r = -0.128), and actions (p = 0.011, r = -0.162). The conclusion of this study is that there is a significant relationship, a negative relationship pattern, and a very weak strength of the relationship between knowledge, attitudes, and preventive actions of COVID-19 with the level of stress among medical students undergoing clinical clerkships at the Faculty of Medicine, Andalas University
Comparison of quality of life, anxiety, and depression levels based on acne vulgaris severity Husna, Annisaul; Yenny, Satya Wydya; Desmawati, Desmawati; Akhyar, Gardenia; Masrul, Masrul; Yulistini, Yulistini
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 8, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Acne vulgaris is a chronic inflammation of the pilosebaceous unit. Although acne vulgaris is not fatal, it can cause psychological effects. This study aimed to compare the quality of life, anxiety, and depression levels based on the severity of acne vulgaris among medical students at Andalas University. Methods: This was an observational-analytic study with a cross-sectional design. It was conducted from May to June 2023. The population included the third-grade students of the Medical Study Program of the Faculty of Medicine, Andalas University, who had acne vulgaris. The respondents were 70 people, recruited with consecutive sampling techniques. This research used Lehmann classifications to classify acne severity, the Cardiff Acne Disability Index (CADI) to assess quality of life, and the Depression Anxiety Stress Scale (DASS-21) to assess anxiety and depression. The statistical analysis used the Kolmogorov-Smirnov test. Results: Most female respondents, aged 20 years old, experienced mild acne vulgaris (84.3%). Additionally, the respondents predominantly had mild quality of life disorders (80%), normal anxiety level (32.9%), and normal depression level (52.9%). The Kolmogorov-Smirnov test found no relationship between the severity of acne vulgaris with quality of life (p = 0.076), anxiety level (p = 0.623), and depression level (p = 0.751). Conclusion: The results showed that most respondents had mild acne vulgaris, mild impairment in quality of life, normal anxiety level, and normal depression level. Statistical tests revealed no significant association between the severity of acne vulgaris and these variables.
Profil Pasien Lupus Eritematosus Sistemik di RSUP Dr. M. Djamil Padang Tahun 2020-2021 Akmal, Elfi Fauzana; Dwitya Elvira; Noverika Windasari; Malinda Meinapuri; Raveinal, Raveinal; Yulistini, Yulistini
Consilium Sanitatis: Journal of Health Science and Policy Vol. 2 No. 2 (2024)
Publisher : EDUPEDIA Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56855/jhsp.v2i2.1867

Abstract

Objective: To understand the profile of SLE patients at RSUP.Dr.M.Djamil Padang period of 2020-2021. Methods: The research is a descriptive type with a retrospective approach. Medical record data were collected using total sampling technique,189 samples met the inclusion criteria. Data analysis using Microsoft Excel. Results: The study found that the majority of characteristics include female patients (95.8%), age group 17-25 years (33.9%), housewives (41.8%), medium-level education (66.1%), and of Minangkabau ethnicity (86.8%). Most patients had a disease duration of ≥ 2 years (78.8%), mild disease activity (36%), the most common clinical manifestation being mucocutaneous involvement (82%). ANA Profile results, the most prevalent finding was positive dsDNA (25.4%). Patients meeting ACR 1997 criteria were 57.1%, SLICC 2012 35.4%, and EULAR 2019 10.6%. The most frequently therapy was a combination of HCQ and glucocorticoids (45%), while the most common patient outcome was survival (96.8%). Conclusion: Majority of SLE patients at RSUP Dr.M.Djamil Padang are in the productive age group with mild disease activity. The majority of patients have good outcome, indicating a favorable prognosis for SLE at RSUP Dr. M. Djamil Padang.
Co-Authors Abdiana Abdiana, Abdiana Adrial Adrial Adrial Adrial, Adrial Afriwardi Afriwardi Aisyah Elliyanti Akmal, Elfi Fauzana Almurdi Almurdi Amel Yanis Anggrainy, Fenty Anisha Fazlisia Arina Widya Murni Ashal, Taufik Asri, Ennesta Aswiyanti Asri Aziz Djamal Azura Darmawan Cimi Ilmiawati, Cimi Delmi Sulastri Desi Kurniati Desmawati Desmawati Dia Rofinda, Zelly Dia Dian Pertiwi Dian Pertiwi Dwitya Elvira, Dwitya Efrida Efrida Elizabeth Bahar Elmatris Sy Erika, Niken Ayu Putri Ermayanti, Sabrina Eti Yerizel Eva Chundrayetti Fairuz Raffelstha Fathiyyatul Khaira, Fathiyyatul Firdawati, Firdawati Gardenia Akhyar Gustia Anugrahwati Gusya Liza, Rini Hardisman Hasmiwati Hendra Herizal Hendra, Gabriel Septian Hendriati, Hendriati Herik Okta Jonanda Hermafasya, Ayu Octarin Herman, Deddy Husna, Annisaul Ilmiati Ilmiati Ilmiawati, Ilmiawati Khairunnisa Lizzikrillah Laila Isrona Liandhu Hakim, Sonya Liliyana Sari Mafaza Mafaza Malinda Meinapuri Masnadi, Nice Rachmawati Masrul Muhamad Imamhamda Muttaqien Muhammad Zulfadli Syahrul Mustafa Noer Netti Suharti Netti Suharti, Netti Nita Afriani Nora Harminarti Noverika Windasari Nur Afany Nur Afrainin Syah Nurhajjah, Sitti Nurul Husna Muchtar Prameswary, Canticha Aulia Putra, Alby Dwinanda Putri, Biomechy Oktomalio Rahmatina B Herman Rahmi, Wahida Rani Armalita RAVEINAL RAVEINAL Restu Susanti Rieke Arya Putri Rima Semiarty Rina Gustia Rosfita Rasyid Rozi Sastra Purna Sagung Adi Sresti Mahayana Satya Wydya Yenny Siti Nurhajjah Syafitri Ayu Asyifa Syamsir, Elmatris Tiara Mardalifa Tomas Apriady Trisuliandre, Muhammad Rizki Wati, Westi Permata Yantri Maputra Yaslinda Yaunin Yenita . Zelly Dia Rofinda Zhuhra, Rahma Tsania