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Selvia Selvia
Universitas Bina Nusantara
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Journal : Jurnal Midpro

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Qualitative and Quantitative Analysis of Hydroquinone in Face Cream with TLC and HPLC Methods Dona, Rahma; Selvia, Selvia
Jurnal MIDPRO Vol 12 No 2 (2020): JURNAL MIDPRO
Publisher : Universitas Islam Lamongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30736/md.v12i2.175

Abstract

Hydroquinone is a chemical compound widely used in cosmetics that acts as a removal of black spots/spots on the face. The use of hydroquinone in cosmetics, according to BPOM regulations, is only allowed with a maximum level of 2%. Excessive use of hydroquinone can cause pigment abnormalities in the face. The materials used in this study were hydroquinone BPFI, 96% ethanol, absolute ethanol, sodium sulfate, methanol (HPLC grade), aquadest, ethyl acetate, and face cream samples (X and Y). Qualitative and quantitative analysis of hydroquinone content in both face cream samples was carried out by TLC and HPLC methods. The results of the qualitative analysis by TLC on both face cream samples (X and Y creams) showed that both samples had the same Rf value 1as the standard hydroquinone Rf while the HPLC chromatogram results of both samples had the same retention time as the standard hydroquinone. Simultaneously, the results of quantitative analysis on cream X samples contained hydroquinone of 3.06% and Y cream of 4.15%. From these results, both face cream samples positive contained hydroquinone with levels> 2%.
Co-Authors Aekram Faisal Afrianto Daud Agung Hartoyo Aisya, Nakhlatul Aisyah Aisyah Aldianor, Aldianor Andi Rahmaniar Andre, Lesis Angelica, Cheryl ashari, septiana Asmayani Salimi Aspadil, Aspadil Astuti, Fanni Azmiana, Risca Bintal Amin Cindrya, Elsa Darmayanti, E Febri Dede Suratman Dengga, Jenovan R Deviani Deviani Dewi Agustina Dewi, Saharani Saari Dianty, Annisa Djais, Siti Yasmine Raqiqah Djunaedi Djunaedi Dunggio, Abdul Rivai Saleh Eva Chris Veronica Gultom Fadly Azhar Fatni Mufit Fitri Wahyuni Fitriani Fitri Ginting, Laditri Br Harahap, Novy Ramini Harahap, Wafiq Azizah Hasibuan, Hasni Periadi Heri Sukendar, Heri Hidayati, Neilin Intang, Nur Intang, Siti Nur Intang, Sitti Nur Irhamni Irhamni Istiyati Mahmudah Jasiah Jasiah Jawoto Nusantoro Jesi Alexander Alim Julia Alamsyah, Sarah Amanda Kamsir, Rita Zahara Khofifah Khofifah Laloan, Nelviana Nelce Lamiang, Lamiang Lasabuda, Taufan Eka Putra Lestari, Dinda Lubis, Nurhasanah Malaha, Naomi Mardhia Soleha, Annisa Masithah, St Masithah, St. Mawaddah, Rezky Alya MB, Andi Rahmaniar Melaweny, Melaweny Mirdad, Jamal Natasha, T. Naswa Nofita Dewi Kok Mesa Nurcahyani, Icha Dian NURMA, TIA Okta Karneli, Okta P, Nur Triningtias Palias, Sosiopater Panjaitan, Tirolyn Paputungan, Cendra Parwati, Eka Pranata, Rio Prasetya, Rayhandi Gilang Pratiwy D, Ulvy Purnama, Shilmy Purnamasari, Feby Rahma Dona Rahmadani, Nofia Rahmaniar MB, Andi Ramadhani Ismi, Dian Rezky Rika Afriyanti Rika Dwi Yulihartika, Rika Dwi Rina Rina Rina Sofiana, Rina Rinaldy, Rahmat Riwun, Riwun Riyana, I Kadek Rizky, Dinda Julia Roziqin, Muhammad Arif Saputri, Nurul Aini Suria Sari, Indah Dewi Septerianie Sutandi Siska, Widya Siswahyudianto Siti Uswatun Hasanah Sri Fitria Retnawaty Sri Mulyani Sri Vandayuli Riorini St. Masithah, St. Masithah Stiawan, Yolanda Ajeng Ayu Sugiyanti, Sri Sulistianti, Maylara Sulistyarini, Sulistyarini Susanti Susanti Suyanti Suwardi Syafruddin Syafruddin Syafruddin2, Syafruddin Syamsu, Rezky Rahmadhani Tay, Cherrie Treasa, Adisty Dwi Triadi, Defri Ummi Kalsum Via, Sel Victor Victor Vitariani, Aisyah Wathon, Nurul Windari, Ratna Wulan, Mayang Yossie Yumiati Yunita, Asma Yusuf, Kurnia Zetra Hainul Putra