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All Journal Buletin Peternakan ADITYA - Pendidikan Bahasa dan Sastra Jawa Berkala Perikanan Terubuk Jurnal Statistika Universitas Muhammadiyah Semarang Perspektif : Review Penelitian Tanaman Industri Jurnal Online Mahasiswa (JOM) Bidang Ilmu Sosial dan Ilmu Politik Jurnal Online Mahasiswa (JOM) Bidang Keguruan dan Ilmu Pendidikan Jurnal Optimasi Sistem Industri PROFIT : Kajian Pendidikan Ekonomi dan Ilmu Ekonomi Jurnal Masharif al-Syariah: Jurnal Ekonomi dan Perbankan Syariah Jurnal Elementer (Elektro dan Mesin Terapan) Jurnal Ilmiah Inovasi JURNAL FARMASIMED (JFM) Jurnal Pancar (Pendidik Anak cerdas dan Pintar) JURNAL EKOBIS DEWANTARA GAUSS: Jurnal Pendidikan Matematika Jurnal Padegogik Akrab Juara : Jurnal Ilmu-ilmu Sosial Journal of Community Development JIKEM: Jurnal Ilmu Komputer, Ekonomi dan Manajemen Lontar Merah: Studi Keilmuan Hukum IKA BINA EN PABOLO : PENGABDIAN KEPADA MASYARAKAT Kajian Moral dan Kewarganegaraan Indonesian Journal on Medical Science (IJMS) Jurnal Dedikasia : Jurnal Pengabdian Masyarakat Jurnal Riset Rumpun Agama dan Filsafat Jurnal Mahasiswa Akuntansi Samudra Jurnal Pengmas Kestra (JPK) Diagnosa: Jurnal Ilmu Kesehatan dan Keperawatan Jurnal Hukum dan Sosial Politik SOSIO YUSTISIA Jurnal Hukum dan Perubahan Sosial Jurnal Ilmiah Multidisiplin Nusantara Jurnal Manajemen Pariwisata dan Perhotelan Perspektif: Jurnal Pendidikan dan Ilmu Bahasa Al-Zayn: Jurnal Ilmu Sosial & Hukum Jurnal Pengabdian Masyarakat dan Riset Pendidikan Jurnal Pendidikan, Bahasa dan Budaya Harmoni Pendidikan: Jurnal Ilmu Pendidikan Journal of Governance and Public Administration Katalis Pendidikan: Jurnal Ilmu Pendidikan dan Matematika Jurnal Ilmiah Nusantara MAXIMAL Abdisembrani: Jurnal Pengabdian Masyarakat Jurnal Indah Sains dan Klinis Serambi Engineering Jukerdi: Jurnal Kewirausahaan Cerdas Dan Digital JURNAL AKADEMIK EKONOMI DAN MANAJEMEN Rabbayani: Jurnal Pendidikan dan Peradaban Islami Pemberdayaan Masyarakat: Jurnal Aksi Sosial Jurnal Riset Multidisiplin Edukasi Jurnal Kesehatan, Rekam Medis dan Farmasi (JUK-Medifa) PESHUM Lumbung Ngabdi: Jurnal Pengabdian Masyarakat Jurnal Ekonomi, Manajemen Pariwisata dan Perhotelan JAMBE: Jurnal Akuntansi Manajemen Bisnis dan Ekonomi
Suci Wulandari
Departemen Teknologi Industri Pertanian, Fakultas Teknologi Pertanian, Institut Pertanian Bogor
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Journal : JURNAL FARMASIMED (JFM)

 1 
Test to Determine The Quercetin Content of Tenggiang (Polystichum setiferum) Using the High Performance Liquid Chromatography (HPLC) Method and Its Antifungal Activity Against Pityrosporum ovale Turnip, Nur Ulina M. Br.; Ratih Anggraeni; Sihombing, Yanna Rotua; Suci Wulandari
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2361

Abstract

Background: Indonesia is a country with high temperature and humidity, which are supporting factors for the development of microbes. One of the microbes that causes infection is the fungus Pityrosporum ovale which can cause dandruff, especially on the scalp. Treatment is usually done using shampoo containing an antidandruff formula. Synthetic chemicals used in hair care have been widely known and used to treat various infections caused by fungi. Tenggiang, a shrub originating from the Toba Samosir area, is used empirically as a wound medicine. In previous studies, Tenggiang has been shown to have antimicrobial, antioxidant, and anti-inflammatory effects. This is related to the content of secondary metabolites found in tenggiang, such as flavonoids, terpenoids/steroids, saponins, and phenolics. Flavonoids, which are secondary metabolites of the polyphenol group. Objective: to measure the levels of quercetin in tenggiang using the HPLC method and to evaluate its antifungal activity against Pityrosporum ovale. Method: measurement of quercetin using the HPLC method and measurement of antifungal activity using the Kirby-bauer method. Results: The measurement results were then calculated as quercetin equivalents, the extract contained a total of 1.33% flavonoids. The retention time data of the standard quercetin was 5.405 minutes and the retention time of the ethanol extract of mackerel was 5.332. The ethanol extract of mackerel was  said to contain quercetin because it had a retention time that was relatively the same as the retention time of the standard quercetin. The extract also showed potential as an antimicrobial agent, where an increase in extract concentration was directly proportional to an increase in the diameter of the inhibition zone. In addition, when compared to the blank, the resulting difference was statistically significant (p <0.05). Conclusion: Tenggiang, extract has antifungal activity and antioxidant potential.
Co-Authors Adib Norma Respati Adrias Adrias Afifatun Nikmah Afrah Junita Agus Anjar Agus Sujarwadi Ahmad Zidan Al Arif Aina Sarah Hafawati Aini Nurul Akhmad Fandik Al Baihaqi Anas Albar Kresna Lukito Nugroho Alditya Putri Yulinarsari Ali Agus Aminah Syarifuddin Anisa Mutiara Rizky Antonio Lisiadi Arya Saputra Ashfiya Rahmawati Asrina Mulyati Aulia Nur Azizah Azahra, Friska Anggita Azida Noor Batubara B. S. Kusmuljono Baru Harahap Bemby Navita Chintia Niltu Farokah Cucu Arum Dwi Cahya DADIK PANTAYA Dahlia Darma Ista Maulana Darmawati Darmawati Deaz Aji Pratama Diah Ayu Lestari Dibyo Susilo Diyah Larasati, Nova Hidayati Dzun Nur&#039;ain Edy Kurniawan Elsa Nurhabibi Eriyatno . Fadilla Suciana Faishal Hasyim Fani Rahmasari Fathul Umam Febby Nanda Utami Felixs Ade Santoso Ferdian, Feri Fergio Rizkya Refin Fitri Mudia Sari Fitri Novita Qothrinada Fitria Naifa Nurul Huda Fitriyanti . Gayatri Aprilia Hamdiah Hana Nurul Hafizah Hariadi Subagja Harmawati Hawaidah Salsabillah An Nahdah hayati, rahmatul Henni Syawal Heriyani Hilda Aprilia Azizi Hilda Hilda Ida Bagus Ngurah Swacita Ida Fitri Anggarini Iesje Lukistyowati Imrona Hayati Indah Noviyanti Intan Sari Ramdhani Irhamni Isnadia Ni&#039;matul Khoiriyah Joko Tri Nugraha Jumadi Jumadi Jumaiti Jumaiti Junita Junita Kuswan Hadji Laila Wahyu Nur Safitri Lenggogeni Arrefa Sago Lia Bayu Natasha Lisa Yuniarti Liska Lestari Lola Tersya Fitriani M. Fajar Hidayah Kembaren M. Faldi Kurniawan M. Iqbal M. Rafif Syauqi Al-Hadi Madona, Putri Mariyam, Rahel MAS DJOKO RUDYANTO Meika Syahbana Rusli Meria Ultra Gusteti Mia Erpinda Moh. Ali Ridho Moh. Bagus Mohamad Soejono Monika Adela Muhammad Haikal Faran Fajri Muhammad Nur Cahyanto Muhammad Wisnu Haikal Nanda Maziyah I’anatillah Nasution, Annio Indah Lestari Naura Nurul Fajri Nazwa Febri Herviana Nila Farihatul Maulidia Nisrina Qurrotu A Nizwan Zukhri Nur Azizah Putri Ferdianti Nur Faizaturrohmah Nur Fitriani NUR HASANAH Nur Lailiyatul Fitriyah Nur Ulina M. Br. Turnip Nurliyani Malau Nurmas Indah Wati NURUL HIDAYAT Oktarina Yusra Panggih Nur Adi Pebriani Nainggolan Pingkan Utari Puan Arliza Azmy Putri Eka Yenita Putri Kurni Wati Racjmalia Vinda Kusuma rambe, nova Ratih Anggraeni Rio, Rio Ripka Ingan Ristanto Utomo Rita Fitri Utami RIZKA AULIA Rohana Rohana Ruben Thomson Napitupulu Saefudin Saefudin Salmayunicha Listie Putri Satria Budi Kusuma Sihombing, Yanna Rotua Siti mutmainnah Sofya Yuliana B. Sopiatun Nawa Sri Novia Martin Sri Setiyo Ningrum - Poltekkes Bhakti Mulia Sukoharjo Sujoko Sumanto Sumanto Sunanda Zalianti Surya Darmawan Syamsiar, Syamsiar Tasya Halimah Nia Purwanti Thobary, Amim Tiara Arianti Tiara Augus Fitriani Tiara, Tiara Augus Fitriani Titi Anjar Pangetsu Toni Toni TOTOK SUYANTO Tuti Meutia Ummi Atiyah Widdya Rahmalina Widiya Widiya Yayuk Suyudi Rahayu Yulia Djahir Yulia Novita Yulistina Nur DS Yustina Yustina Zaili Rusli Zetri Rahmat