Article Per Year (5 Year)
p-Index From 2021 - 2026
3.742
P-Index
This Author published in this journals
All Journal International Journal of Public Health Science (IJPHS) Media Kesehatan Masyarakat Indonesia JURNAL GIZI INDONESIA Journal of Nutrition College Jurnal Kedokteran Indonesia Nexus Kedokteran Komunitas LINK Indonesian Journal of Human Nutrition Jurnal Gizi dan Kesehatan International Research Journal of Management, IT & Social Sciences Ilmu Gizi Indonesia Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) Jurnal Gizi Klinik Indonesia Jurnal Gizi dan Pangan Soedirman (JGPS) Indonesian Journal of Medicine Indonesian Journal of Global Health research Jurnal Dunia Gizi Nusantara Science and Technology Proceedings PROFESI (Profesional Islam): Media Publikasi Penelitian Proceedings of the International Conference on Nursing and Health Sciences Proceeding ISETH (International Summit on Science, Technology, and Humanity) Journal of International Conference Proceedings Jurnal Penyakit Dalam Indonesia Media Penelitian dan Pengembangan Kesehatan Jurnal Info Kesehatan
Budiyanti Wiboworini
Fakultas Kedokteran, Universitas Sebelas Maret
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

Published : 38 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : JURNAL GIZI INDONESIA

 1 
Red dragon fruit juice in reducing ros levels and insulin resistance In rats with type 2 diabetes mellitus model Putri, Mahendri Deayu; Wiboworini, Budiyanti; Dirgahayu, Paramasari
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 10, No 1 (2021): December
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.10.1.6-14

Abstract

Background: The peel of red dragon fruit (Hylocereus polyrhizus) had been proven to have a total polyphenol content and total flavonoids 2 to 3 times more than its flesh. These components could reduce oxidative stress and maintain the function of pancreatic beta cells, which could affect blood sugar levels.Objectives: This study aimed to test the red dragon fruit juice using peel and flesh to reduce oxidative stress and insulin resistance in T2DM model rats.Materials and Methods: This study was a true experimental study with a randomized controlled trial, with a Matching Pretest Post-test Control Group Design. We used 21 white male rats (Rattus norvegicus) Wistar strain which was divided into three groups: (P1) negative control group (induced Streptozotocin + Nicotinamide induction), (P2) positive control group (given Streptozotocin + Nicotinamide and given Metformin HCl induction 0,9 mg/kg BW, and (P3) Red Dragon fruit group (induced Streptozotocin + Nicotinamide and given Red Dragon Fruit juice 3.6 ml / 200 g BW / day given for 14 days. The data were analyzed using a one-way ANOVA test, paired t-test, and Post Hoc.Results: After 14 days of intervention, the average HOMA-IR levels were as follows: negative control group (Mean=8.32; SD=0.26), positive group (Mean 4.89; SD=0.29), and the Red Dragon Fruit intervention group (Mean=4.65; SD=0.30). The average MDA levels were as follows: control group (Mean = 9.08; SD = 0.68), positive group (Mean=3.34;SD=0.22), and the red dragon fruit intervention group (Mean = 3.05; SD = 0.47). Both the Metformin group and the Red Dragon Fruit group had low HOMA-IR and MDA levels compared to the negative control group.Conclusions: When administered alone, red dragon fruit and metformin effectively reduced HOMA-IR and MDA levels in rats with type 2 DM. Red dragon fruit can be used as an alternative to metformin because of its effectiveness in reducing plasma HOMA-IR and MDA.
Co-Authors AA Subiyanto, AA Adi Prayitno Agustina Indri Hapsari Ali Djamhuri Ari Natalia Probandari Ari Probandari Arum, Wuryan Dewi Miftahtyas Ayu Kusuma Dewi Ayusari, Amelya Aughustina Ayusari, Amelya Augusthina Azzahrah, Aisyah Bambang Purwanto Banun Rohimah, Banun Betania, Sakha Ukta Billah, Muhammad Muayyad Brian Wasita Budiastuti, Veronika Ika Dhoni Akbar Ghozali Didik Gunawan Tamtomo Diffah Hanim Dono Indarto Dwi Rahayu ernawati, ammik Ernawati, Erni Firnanda, Sani Widya Handayani, Sutartinah Sri Hanifah, Rosalinda Abir Hasibuan, Wahyu Aulia Jokomarsono, Elisabet Puspita Kezia Elian Devina khusnul khotimah Kuntari Astriana, Kuntari Kusmadewi Eka Damayanti kusnandar kusnandar Kusumawati, Ratna Kusumawati, Ratna Lilik Retna Kartikasari Lourena, Crysty Mahyaningtyas, Fransisca Pradnya Majestika Septikasari, Majestika Mariestu, Farah Kurnia Maulidya, Rizki Muhammad Akhyar Nilasari, Aprilina Citra Ayu Nur Hafidha Hikmayani Nurgajayanti, Cendi Paramasari Dirgahayu Pasaribu, Sudana Fatahillah Putri, Mahendri Deayu Putri, Yulia Rahmawati Wibowo Qadrijati, Isna Retnowati, Sri Sanjaya, Evan Japutra SANTOSO SANTOSO Sapja Anantanyu, Sapja Sari, Amelya Augusthina Ayu Sari, Atriany Nilam Shabrina, Amalina Shanti Listyawati Sinaga, Ruth Dearani Sogen, Maria Dolorosa P. Sri Mulyani Sugiarto S Sugiarto, S Sukamto, Ika Sumiyarsi Suminah Suminah, Suminah Supriyadi Heri Respati, Supriyadi Heri Tjung, Vivienne Tri Nugraha Susilawati Tri Rejeki Andayani Valensia, Yualeny Wahidah, Nurul Jannatul widardo, Widardo Widyaningsih, Vitri Wrisnijati, Dita Wrisnijati, Dita Wulandari, Anggraini yulia lanti retno dewi Yuniarti, Windy