Eric Edwin Yuliantara
Department Of Obstetrics And Gynaecology, Faculty Of Medicine, Universitas Sebelas Maret/Dr. Moewardi General Hospital, Surakarta

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Syphilis in Pregnancy: Education to Increase Knowledge in Reproductive Couples Sulistyowati, Sri; Bachnas, Muhammad Adrianes; Yuliantara, Eric Edwin; Anggraini, Nutria Widya Purna; Respati, Supriyadi Hari; Nurinasari, Hafi; Ridwan, Robert; Astetri, Lini; Nuur, Aliffudin; Pradana, Muhammad Denny Gagah; Khoeronisa, Siti; Rahmawati, Oktantia Dyah
Journal of Maternal and Child Health Vol. 10 No. 4 (2025)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/thejmch.2025.10.04.01

Abstract

Background: Syphilis is believed to be one of the oldest diseases, first discovered in the late 15th century. Indonesian Ministry of Health reported a total of 76,923 new cases in 2020. WHO has set an ambitious target to reduce the incidence by 90% before 2030, in spite of slow global  response.  This number is lower than the number obtained in 2019, which was 4,169 people. Syphilis can be transmitted through sexual contact, blood transfusion, and vertical mother-to-child transmission (MTCT). It is estimated that the risk of transplacental infection ranges from 20-80%, depending on various factors, such as the stage of infection in the mother. This study aimed to assess the effect of counseling in increasing patient knowledge of syphilis cases in pregnancy. Subjects and Method: This was a quasi experiment conducted at obstetrics and gynecology department in Dr. Moewardi Hospital, Surakarta, Central Java, Indonesia, in June 2025. A sample of 84 pregnant women was selected for this study. The independent variable was counselling. The dependent variable was knowledge about Syphilis in pregnancy. Knowledge was tested before and after counselling. The data were examined using independent t test.             Results: The knowledge score of pregnant women about syphilis after the intervention (Mean= 77.14; SD= 13.85) was higher than before (Mean= 56.43; SD= 15.88), and it was statistically significant (p <0.001). Conclusion: The results of this study indicate that this recovery is effective in improving understanding of syphilis cases in pregnancy in obgyn polyclinic patients at Dr. Moewardi Hospital.
Multidisciplinary Approach of Placenta Accreta Spectrum Management to Reduce Blood Loss and Prevent Organ Injury in Referral Center Nugraha, Gagah Baskara Adi; Yuliantara, Eric Edwin
Indonesian Journal of Obstetrics and Gynecology Volume 12 No. 3 Jully 2024
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v12i3.2098

Abstract

Objective: To investigate the differences in blood loss and organ injury at our PAS referral center over the past six years.Methods: This retrospective analytical study included 150 subjects diagnosed with PAS based on histopathological findings from 2018 to 2023 at the PAS Center of Dr. Moewardi Regional Hospital, Surakarta, Indonesia. Subjects were divided into two groups: before 2020 and after 2021, based on multidisciplinary team appointments.Results: The highest number of Placenta Accreta Spectrum (PAS) cases occurred in 2020, with 36 patients. Hysterectomy was the most frequently performed procedure for managing PAS in all groups. However, differences in blood loss, organ injury, and length of hospital stay between the periods from 2018 to 2020 and 2021 to 2023 were statistically significant (p < 0.05).Conclusion: Multidisciplinary approaches involving various medical specialties and teams are essential to ensure maternal safety and effectively manage massive blood loss and organ damage during PAS surgery procedures.Keywords: Placenta accreta spectrum, Blood loss reduction, Organ injury prevention.
Transfusi Masif dan Tatalaksana Intensif Post Histerektomi pada Plasenta Akreta Trsitiarti, Alfi Marita; Yuliantara, Eric Edwin
Jurnal Biomedika dan Kesehatan Vol 7 No 2 (2024)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2024.v7.145-151

Abstract

Background Placenta accrete remains a problem in developing countries. The incidence rate has increased over the last 30 years accompanied by the risk of maternal death. Bleeding is still the main cause of death. This rising incidence rate has increased Sectio Caesaria (SC) operations, resulting in greater treatment costs. This is due to its cost management as it requires intensive care and massive use of blood transfusions. This study aims to describe the characteristics, management, and maternal outcomes of placenta accrete spectrum cases. Methods A Cross-sectional study was conducted at Moewardi Hospital Surakarta between January 2016 and December 2021. Sample selection was based on medical records with a suspected diagnosis of PAS. A total of 121 cases of placenta accrete spectrum had been confirmed by anatomical pathology results were analyzed Assessments were carried out on maternal characteristics, risk factors, MAP score, intraoperative management, and postoperative care. Statistical analysis was carried out with a 95% confidence interval (CI), chi-square test, and odds ratio assessment using SPSS edition 23. Results Hysterectomy has more morbidity and maternal complications than conservative management in blood loss, massive transfusion, iatrogenic incident, and a long stay in the Intensive care unit. Conclusions The high rate of morbidity in the management of the placenta accrete spectrum requires comprehensive management to reduce maternal mortality.
Hypoxia Inducible Factor-1-Alpha Expression on Preeclampsia Mice Model With L-Arginine Administration Anggraini, Nutria Widya Purna; Sulistyowati, Sri; Bachnas, Muhammad Adrianes; Yuliantara, Eric Edwin; Prabowo, Wisnu; Budihastuti, Uki Retno
Folia Medica Indonesiana Vol. 57, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

Preeclampsia is hypertension in pregnancy that affects 2% to 8% of pregnancies worldwide and causes significant maternal and perinatal morbidity and mortality. In the pathogenesis of preeclampsia, placental hypoxia plays an important role, associated with excessive trophoblast apoptosis resulting in decreased trophoblast and spiral arteries invasion. This placental hypoxic condition will induce increased expression of Hypoxia Inducible Factor -1-Alpha (HIF-1-A). L-Arginine is a potent vasodilator presumably to improve preeclampsia placental hypoxic conditions and reduce HIF-1-A expression. This study was an experimental study with a parallel-group post-test only design. Thirty-six preeclamptic mice models were divided into 2 groups. The control group (K1) 18 preeclamptic mice model without treatment and the treatment group (K2) 18 preeclamptic mice given L-Arginine. The independent variable was the administration of L-Arginine and the dependent variable is the placental HIF-1-A expression. Statistical analysis used unpaired t-test on normal data distribution, and Mann Whitney test on abnormal data distribution. The mean of placental HIF-1-A expression K1 was 2.47 ± 1.65 with a minimum value of 0.4 and a maximum value of 6.6. At K2 0.93 ± 0.55 with a minimum value of 0.0 and a maximum value of 2.0. Statistical tests showed that the placental HIF-1-A expression in the treatment group was significantly lower than that in the control group (p <0.001). In conclusion, the expression of HIF-1-A in preeclamptic mice model placenta decreased with L-Arginine administration.
LEARNING TO PREVENT AND BREAK THE CHAIN OF TRANSMISSION OF COVID-19 BY VACCINATE WOMEN, PREGNANT AND BREASTFEEDING MOTHERS THROUGH THE WEBINAR Bachnas, Muhammad Adrianes; Anggraini, Nutria Widya purna; Sulistyowati, Sri; Yuliantara, Eric Edwin; Prabowo, Wisnu; Nugraha, Gagah B Adi; Firmansyah, Aldi; Prameilita, Dympna
Placentum: Jurnal Ilmiah Kesehatan dan Aplikasinya Vol 10, No 1 (2022): February
Publisher : Program Studi Kebidanan Fakultas Kedokteran Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/placentum.v10i1.52880

Abstract

Background: The incidence of Covid-19 in women, pregnant, and breastfeeding mothers is still high. Currently, the government is trying to prevent and break the chain of Covid-19 transmission by vaccination. However, knowledge about Covid-19 vaccination is still limited. Therefore, Indonesian Obstetrics and Gynecology Association/Perkumpulan Obstetri dan Ginekologi Indonesia  (POGI) members, as the spearhead of women's health, play an essential role in breaking the chain of transmission by providing knowledge about Covid-19 vaccination.Methods: All member of POGI and Youth POGI in Surakarta was educated by online method via the webinar zoom application. The level of knowledge was evaluated pre and post-webinar by using a questionnaire to see the significance.Result: Analysis of 110 participants with paired t-test obtained an average pretest value of 44.82 while the average post-test value was 57.45, with a significance value of p=0.001 (p<0.05). The results of the analysis with the Chi-square test obtained p = 0.002 (p <0.05) and OR = 23.40.Conclusion: There is an increased understanding of preventing and breaking the chain of transmission of Covid-19 in women, pregnant, and breastfeeding mothers by vaccinating youth POGI and POGI members after webinar and discussion, with a significance value of p=0.001 (p<0.05). Webinars and discussions on preventing and breaking the chain of transmission of Covid-19 to women, pregnant, and breastfeeding mothers with vaccination by researchers provided 23.40 times better understanding than before the webinar and discussions were given.   
Early Detection and Good Team Collaboration for Preventing Maternal Death Caused by Placenta Accreta Spectrum Disorder Yuliantara, Eric Edwin; Bachnas, Muhammad Adrianes; Anggraini, Nutria Widya Purna; Prabowo, Wisnu; Nugraha, Gagah Baskara Adi; Chasanah, Meriska Dewi; Alim, Fadel Muhammad S.; Merina, Hikmah F.
Placentum: Jurnal Ilmiah Kesehatan dan Aplikasinya Vol 11, No 2 (2023): August
Publisher : Program Studi Kebidanan Fakultas Kedokteran Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/placentum.v11i2.71047

Abstract

Background: Placenta accreta spectrum (PAS) is considered one of the most harmful pregnancy conditions, as it is strongly linked with maternal morbidity and mortality. An accurate and early prenatal diagnosis of PAS allows time for a multidisciplinary team to plan the best course of action for delivery management. The aim of this study is to describe placenta accreta spectrum management and outcomes with early detection and a multidisciplinary team approach.Method: A retrospective cohort study was conducted on 167 cases of placenta accreta from 2016 to 2021. Medical records were then reviewed, and data were collected for delivery management and maternal outcome, including estimated amounts of bleeding, urinary tract injury, delivery time, ICU referral, and maternal death.Result: Delivery management (hysterectomy and conservative management) and maternal bleeding were significantly associated with MAP score (p < 0.05), while urinary tract injury, delivery time, ICU admission, and maternal death were not significantly associated (p > 0.05). 55.1% of patients underwent hysterectomy, and the rest 44.9% underwent conservative surgery. Massive bleeding of more than 2500 mL happened in 54.5% of patients, and the rest 45.5% managed to bleed less than 45.5%. Preterm deliveries accounted for 29.9% of all deliveries, with the remaining 70.1% being term. 5.4% of patients experienced urinary tract injuries. 6.6% of patients were referred to the intensive care unit. The maternal mortality rate is 4.8%.Conclusion: Early detection of the placenta accreta spectrum, as well as good collaboration among members of a multidisciplinary team from various medical fields, are required to ensure the mother and baby's safety and survival.
The Effectiveness of Letrozole-Electroacupuncture Adjuvant Therapy in Reducing Resistance and Pulsatility Indices in Women with Polycystic Ovarian Syndrome Dhamayanti Eka Octavia; Uki Retno Budihastuti; Eriana Melinawati; Nutria Widya Purna Anggraini; Eric Edwin Yuliantara; Ida Nurwati; Cahyono Hadi
Journal of Maternal and Child Health Vol. 5 No. 4 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (35.881 KB)

Abstract

Background: Polycystic Ovarian Syndrome (PC