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All Journal Farmaka Dharmakarya : Jurnal Aplikasi Ipteks Untuk Masyarakat Jurnal Riset Kimia Indonesian Journal of Pharmaceutical Science and Technology Jurnal Farmasi Klinik Indonesia IDJP (Indonesian Journal of Pharmaceutics) As-syifaa Jurnal Farmasi Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Indonesian Food Science and TechnologyJournal Pharmacology and Clinical Pharmacy Research JSFK (Jurnal Sains Farmasi & Klinis) Pharmaceutical Journal of Indonesia JURNAL FARMASI GALENIKA Majalah Farmasetika Jurnal Ilmiah Farmasi Farmasyifa ad-Dawaa : Journal of Pharmaceutical Sciences Jurnal Sabdariffarma: Jurnal Ilmiah Farmasi Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang MAHESA : Malahayati Health Student Journal Jurnal Abdimas Indonesia : Jurnal Abdimas Indonesia Indonesian Journal of Biological Pharmacy Journal of Pharmaceutical and Sciences. Medical Laboratory Journal Media Kesehatan Politeknik Kesehatan Makassar Journal of The Indonesian Society of Integrated Chemistry Vitalitas Medis : Jurnal Kesehatan Dan Kedokteran Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Journal of Agropharmacy Jurnal Farmasi Galenika
Patihul Husni
Departemen Farmasetika Dan Teknologi Farmasi, Fakultas Farmasi, Universitas Padjadjaran, Indonesia
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Other

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Pengembangan Lotion Anti Nyamuk Ekstrak Daun Kenikir (Tagetes erecta L.) Dengan Variasi Konsentrasi Setil Alkohol Mikhania Christiningtyas Eryani; Dewi Rashati; Asa Falahi; Patihul Husni; Eka Yulia Agustin
JURNAL FARMASI GALENIKA Vol 13 No 1 (2026): Jurnal Farmasi Galenika Volume 13 No 1
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v13i1.423

Abstract

The use of chemical-based mosquito repellents has excellent repellent power, but their use can cause hypersensitivity and irritation. In Indonesia, there are several plants that contain essential oils and have mosquito repellent effects. One of them is cosmos (Tagetes erecta L). Cosmos leaf extract is formulated into a lotion preparation so that it can adhere to the skin for a longer time, thus providing longer-lasting mosquito repellent properties. This research aims to determine the effect of varying cetyl alcohol concentrations on the physical properties of lotion. There are 3 lotion formulas used with cetyl alcohol concentrations of 2% (F1), 2.5% (F2), and 3% (F3). The research results show that F1 has a thick texture and brownish-yellow color, F2 has a thick texture and green color, and F3 has a very thick texture and green color. All formulas are homogeneous. F1, F2, and F3 had pH values of 7.5±0, 7.5±0, and 7.9±0, respectively. F1, F2, and F3 have respective viscosities of 20±0 dPas, 30±0 dPas, and 35±0 dPas. F1, F2, and F3 had spreadability values of 8.48±0.51 cm, 7.81±0.05 cm, and 7.10±0.37 cm, respectively. The conclusion of this study is that variations in cetyl alcohol concentration affect the texture, color, pH, viscosity, and spreadability of the lotion.
Pengaruh Variasi Konsentrasi Cocamidopropyl Betaine Pada Karakteristik Fisik Sampo Ekstrak Kering Teh Hijau Patihul Husni; Rini Silviya; Uswatul Hasanah; Mikhania Christiningtyas Eryani; Mayang Kusuma Dewi; Norisca Aliza Putriana; Melinda Januarti
JURNAL FARMASI GALENIKA Vol 13 No 1 (2026): Jurnal Farmasi Galenika Volume 13 No 1
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v13i1.435

Abstract

Hair growth–promoting preparations are used to prevent hair damage problems. Compounds contained in green tea extract have activity as hair growth promoters. This study aimed to obtain data on the effect of variations in cocamidopropyl betaine concentration on the physical characteristics of shampoo containing dry green tea extract. The formulations were prepared in three formulas (F1, F2, and F3) containing different concentrations of cocamidopropyl betaine (8.25%, 8.5%, and 8.75%). The research stages included formulation followed by physical evaluation, including organoleptic properties, homogeneity, pH, viscosity, and foam stability. The results showed that the shampoo preparations were viscous liquids, brown in color, with a characteristic odor, pH of 7–8, viscosity of 250–300 cPs, and foam stability of 15–20 cm. The conclusion of this study is that variations in cocamidopropyl betaine concentration affect the physical characteristics of shampoo containing dry green tea extract. The concentration of cocamidopropyl betaine greatly influences the physical stability of the shampoo, with F3 as the best formula based on physical evaluation, which contains 8.75% cocamidopropyl betaine.
Duck Egg Shell and Bay Leaf Extracts (Syzygium polyanthum [Wight] Walp.) Toothpaste Development Using Sodium CMC as a Binder ERYANI, MIKHANIA; perwita, tista; aditama, agnis; rashati, dewi; husni, patihul; wijiani, nina
Pharmaceutical Journal of Indonesia Vol. 11 No. 2 (2026)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Background: Toothpaste is a semi-solid preparation that helps shield teeth from bacterial harm by including abrasive compounds and other helpful elements. Duck eggshells are one of the natural materials that contain calcium carbonate as an abrasive, while bay leaves are a plant that hassantibacterial properties. Objectives: This study aims to formulate duck egg shell toothpaste and bay leaf extract (Syzygium polyanthum [Wight] Walp.) with sodium CMC variation concentrations. Methods: toothpaste is formulated with variation CMC concentration are 3% for F1; 4.5% for F2; and 6% for F3 and evaluate its physical properties. The physical properties tests conducted included organoleptic tests, homogeneity, pH, viscosity, spreadability, and foam height. Results: From the research results, there is an effect of varying sodium CMC concentrations on the physical properties of pH, viscosity, spreadability, and foam height, but no effect of varying sodium CMC concentrations on the organoleptic and homogeneity properties. Conclusions: The research indicate that all formulas meet the requirements for the physical property tests of duck egg shell toothpaste and bay leaf extract.
Duck Egg Shell and Bay Leaf Extracts (Syzygium polyanthum [Wight] Walp.) Toothpaste Development Using Sodium CMC as a Binder ERYANI, MIKHANIA; perwita, tista; aditama, agnis; rashati, dewi; husni, patihul; wijiani, nina
Pharmaceutical Journal of Indonesia Vol. 11 No. 2 (2026)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Background: Toothpaste is a semi-solid preparation that helps shield teeth from bacterial harm by including abrasive compounds and other helpful elements. Duck eggshells are one of the natural materials that contain calcium carbonate as an abrasive, while bay leaves are a plant that hassantibacterial properties. Objectives: This study aims to formulate duck egg shell toothpaste and bay leaf extract (Syzygium polyanthum [Wight] Walp.) with sodium CMC variation concentrations. Methods: toothpaste is formulated with variation CMC concentration are 3% for F1; 4.5% for F2; and 6% for F3 and evaluate its physical properties. The physical properties tests conducted included organoleptic tests, homogeneity, pH, viscosity, spreadability, and foam height. Results: From the research results, there is an effect of varying sodium CMC concentrations on the physical properties of pH, viscosity, spreadability, and foam height, but no effect of varying sodium CMC concentrations on the organoleptic and homogeneity properties. Conclusions: The research indicate that all formulas meet the requirements for the physical property tests of duck egg shell toothpaste and bay leaf extract.
Stability Study Of Paracetamol Drops Mixed With Date Juice Concentrate During 24 Hours Of Storage Under Room Temperature (≤30 °C) And Refrigerated Temperature (2–8 °C) Patihul Husni; Rina Haryani; Ginayanti Hadisoebroto; Norisca Aliza Putriana; Mikhania Christiningtyas Eryani
JURNAL FARMASI GALENIKA Vol 13 No 2 (2026): August 2026
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v13i2.463

Abstract

Parents occasionally mix paracetamol drops with date juice concentrate before administration a paracetamol drops to children to mask the bitter taste of the paracetamol. Such a practice may result in interactions between paracetamol and the chemical constituents present in date juice concentrate, potentially affecting the drug's stability. This study aimed to evaluate the stability of paracetamol concentration in paracetamol drops after being mixed with date juice concentrate under different storage conditions. Paracetamol drops were mixed with date juice concentrate and stored at room temperature (≤30°C) and refrigerated conditions (2–8°C). Organoleptic properties and paracetamol concentration were evaluated at 0, 5, 10, 15, 20, 30, 45, 60, 120, 180, and 1440 minutes using UV–Visible spectrophotometer. The organoleptic evaluation demonstrated that the mixture remained stable as a dark brown liquid with the characteristic odor for up to 24 hours under both storage conditions. Results showed a decrease in paracetamol concentration during 24 hours of storage; however, because the study did not include a paracetamol-only control group, this decrease cannot be definitively attributed to date juice concentrate, and the interpretation should therefore be limited to the observed change in paracetamol concentration in the mixture during storage. Under room temperature and refrigerated conditions, the remaining paracetamol concentrations after 24 hours were 43.291 ± 0.437% and 38.527 ± 0.019%, respectively. Statistical analysis indicated no significant difference in the reduction of paracetamol concentration between the two storage conditions. In conclusion, mixing of paracetamol drops with foods or beverages, such as date juice concentrate, may affect paracetamol stability and can cause reducing of paracetamol concentration.
Pengetahuan, Sikap, dan Perilaku Mahasiswa Prodi Non Kesehatan Universitas Padjadjaran Pada Penggunaan Produk Kosmetik Halal Norisca Aliza Putriana; Muhammad Dimas; Patihul Husni; Mayang Kusuma Dewi; Soraya Ratnawulan Mita
JURNAL FARMASI GALENIKA Vol 13 No 2 (2026): August 2026
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v13i2.444

Abstract

In Indonesia, cosmetic products are required to obtain halal certification, as stipulated in Law No. 33 of 2014 on Halal Product Assurance (Jaminan Produk Halal/JPH), which states that the government is responsible for implementing the halal assurance system. This requirement is further reinforced by Article 141 of Government Regulation No. 39 of 2021, which regulates the mandatory halal certification of cosmetic products until October 17, 2026. One of the challenges in halal certification for cosmetics is the use of imported raw materials whose halal status cannot always be guaranteed. This condition may influence consumers’ decisions regarding the selection and use of halal cosmetic products. This study aimed to assess the knowledge, attitudes, and behaviors of non-health students at Universitas Padjadjaran regarding the use of halal cosmetic products. A descriptive cross-sectional study was conducted using an online questionnaire. A total of 248 students aged ≥18 years were consecutively recruited, and data were collected from April to May 2023. Data were analyzed using the chi-square, Kruskal-Wallis, and Spearman’s rho tests with SPSS version 28. The results showed that 59.27% of non-health students had a positive level of knowledge regarding halal cosmetic products. More than half of the respondents demonstrated positive attitudes and behaviors toward the use of halal cosmetics, with percentages of 56.45% and 60.89%, respectively. Age was significantly associated with behavior in usage decisions (p=0.008; OR=1.607; 95% CI: 0.939–2.751). Faculty differences were also significantly associated with knowledge (p=0.006), attitudes (p<0.001), and behavior in usage decisions (p=0.005). Overall, non-health students at Universitas Padjadjaran demonstrated positive tendencies in knowledge, attitudes, and behaviors toward halal cosmetics, with positive correlations among these variables in their decisions to use halal cosmetic products.
Utilization of 1-(3-aminopropyl)-imidazole in development of pH-sensitive nanocarrier for anticancer drug delivery Husni, Patihul Husni; Aliza Putriana, Norisca
Indonesian Journal of Pharmaceutics Vol 4, Issue 1, Jan - April 2022
Publisher : Universitas Padjadjaran (Unpad)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/idjp.v4i1.40691

Abstract

pH-sensitive nanocarriers have demonstrated as successful drug carriers due to the higher drug accumulation at the tumor site by pH dependent release at acidic tumor microenvironment. Imidazole can be utilized to obtain the pH-sensitive nanocarriers. One of imidazole-based compounds used by researchers in development of pH-responsive carriers is 1-(3-Aminopropyl)-imidazole. This review is focused on utilization of 1-(3-aminopropyl)-imidazole to develop pH-sensitive nanocarrier especially for delivery of anticancer drug. In addition, this review also shows research performed by researchers to develop pH-sensitive nanocarrier for anticancer drug delivery using 1-(3-aminopropyl)-imidazole to prepare imidazole-based pH-sensitive nanocarriers. The data were collected from published journals with 15 and 20 journals as primary and supporting literatures, respectively. Properties of imidazole groups to deprotonate at pH 7.4 and protonate at pH ≤ 6.5 implies that the drug release was pH-dependent, leading to limited release of drug from carriers under physiological pH conditions and diminishing the drug’s effect in blood circulation before reaching the tumor site, resulting in more effective anticancer activity.
Co-Authors Adi Prayitno Aditama, Agnis Agita, Kiva Agnis Pondineka Ria Aditama Ahmad Muhtadi Ahmad Muhtadi Alicia Ima Dara Alika Nuansa Pratiwi Alyanis Mufid SWM Ami Tjitraresmi Ami Tjitraresmi, Ami Anggia Diani Amalia Anggun Putri Perwira Anis Yohana Chaerunisaa, Anis Yohana Annisa Luthfiyah Handini ANUGRAHANI YUNIAR EKAWATI Apriyani, Mila Ardian Baitariza Ardian Baitariza Ardian Baitariza, Ardian Aryani, Annisa Fitri Asa Falahi Astri Sherly Inggriani Astri Sherly Inggriani ASTRI SULASTRI Ayuning Trias, Diah Aziz, Calista Sasikirana Finola Azizul Hakim Billa Nidia Hikmatiana Budianto, Muhamad Oke Cahya Lestari, Riska Carolina, Theresia Denok Risky Ayu Paramita Devani Olivia Winardi Dewi Rashati Dolih Gozali Dolih Gozali Dwi Puji Astuti Een herliani Eka Yulia Agustin Ella Masliana Dewi Erika Herawati, Irma Eryani, Mikhania Christiningtyas Fairuzati Anisah Murthadiah Fakhirah, Maitsa Alya Fakhri Rabbani FARIANTI EKO NUR KHASANAH Fauziah, Neneng Alifia Nur FIKAMILIA HUSNA Firmansyah Firmansyah Ghifari, M Alvien Hadisoebroto, Ginayanti Hazrina, Aghnia Henny Lucida Hery Diar Febryanto Hosiana, Vinny Ida Musfiroh Ida Musfiroh -, Ida Musfiroh Imam Adi Wicaksono Indriana Agustin Claradila Frinda IRMA RAHAYU LATARISSA Januarti, Melinda Judy Handojo, Kukuh Junaedi Junaedi Junaedi Junaedi Kartika Puspitaningrum Khanifah Hidayati Puspa Negara Khoirunnisa, Arina Kurniati, Bunga Dian Kurniawan Syah, Insan Sunan Kusdi Hartono, Kusdi La Ode Zahid Al Hajri Nur Salam Layyareza, Rania Talinta Luluk Luqyana Mahdiyah Luthfiah, Annisa Mala Fitriani Mayang K. Dewi Mayang Kusuma Dewi MEGA HIJRIAWATI Melinda Januarti Melinda Januarti Muchamad Luthfi Fadhiilah Muhaimin Muhaimin Muhammad Dimas Mulyani, Tuti Sri Muthia Izati Mutia Dwi Lestari Nadya Indah Dewanti NADYA INDAH DEWANTI, NADYA INDAH Nafisa Nurfatia Hidayat Nina Wijiani Norisca A. Putriana Norisca A. Putriana Norisca Aliza Putriana Nur Aisyah NUR DIANA HADAD Nurulita Dina Ulfah Nuryani, Tri Winarsih Permatasari, Lina Putri Perwira, Anggun Putri perwita, tista Puspitaningrum, Kartika Putri, Refitha Nurul Rashati, Dewi Ratnadani Amalia Safitri Ratnawati, Aini Regina Liviandari RESTIKA ERIA PUTRI Rina Haryani Rini Hendriani Rini Silviya Riska Cahya Lestari Safitri, Manzil Salsabila, Annisa Siti Santi Sinala SHEILA PRATIWI Sigalingging, Asima Rohana Silvia, Nurfianti Siti Nur Azizah, Siti Nur Sitinjak, Bernap Dwi Putra Soewahju, Renata Bella Soraya Ratnawulan Mita Soraya Ratnawulan Mita Mita SORAYA RATNAWULAN MITA, SORAYA RATNAWULAN Sri Agung Fitri Kusuma Sriwidodo Sriwidodo Syuhuriah, Ainin Taofik Rusdiana Tryani Sutisna Putri, Sussy Uswatul Hasanah Uswatul Hasanah Uvita Kafilatul Ikhrom Vinny Hosiana Vista Kamilania Widayanti Supraba Wirna Grace Tua Sihombing Yasarah Hisprastin Yoga Windhu Wardhana Yoshihito Shiono Yosita Aulia Mustofa Yuli Agung Prasetyo Yuni Ruspriyani YUNIKE KARUNIA PUTRI Yusuf, Marsha Afifah Zelika Mega Ramadhania, Zelika Mega