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Formulasi Dan Evaluasi Fisik Lipstik Dari Ekstrak Kulit Umbi Bit (Beta vulgaris L.) Eryani, Mikhania Christiningtyas; Aditama, Agnis Pondineka Ria; Husni, Patihul; Permatasari, Lina Putri
JURNAL FARMASI GALENIKA Vol 12 No 3 (2025): Jurnal Farmasi Galenika Volume 12 No 3
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v12i3.417

Abstract

Lipstick is a cosmetic used to add color to the lips. Natural dyes that can be used as a lipstick component are beet (Beta vulgaris L.) skin extract. The skin of beet contains betacyanin which can give color to the lips. This study aims to determine the effect of varying concentrations of beet skin extract on the physical properties of lipstick. There are 3 lipstick formulas used with a 1% (F1), 2% (F2), and 3% (F3) concentration of beet skin extract. The research results show that F1 is pink, F2 is red, and F3 is dark red. The entire formula has even spreadability. The pH values of F1, F2, and F3 are 4.9±0.173, 5±0.3, and 5.3±0, respectively. The melting points of F1, F2, and F3 are 50.66±1.15°C, 52.66±1.15°C, and 53.66±0.58°C, respectively. The conclusion of this study is that variations in the concentration of beet extract affect the color, pH, and melting point of lipstick but do not affect the spreadability of lipstick.
Pengembangan Sediaan Losio Ekstrak Buah Naga Putih Husni, Patihul; Budianto, Muhamad Oke; Baitariza, Ardian; Eryani, Mikhania Christiningtyas; Febryanto, Hery Diar; Januarti, Melinda
JURNAL FARMASI GALENIKA Vol 12 No 3 (2025): Jurnal Farmasi Galenika Volume 12 No 3
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v12i3.419

Abstract

White dragon fruit (Hylocereus undatus) is a tropical fruit from a type of cactus plant that contains various powerful antioxidants. The purpose of this study was to obtain the best lotion formula containing extract of white dragon fruit based on physical evaluation. Three lotion formulas (F1, F2, F3) containing 7,5% white dragon fruit extract were prepared in this study. Physical assessment of the lotion preparation included organoleptic tests, homogeneity, pH determination, and viscosity evaluation. The results showed that the preparation was in the form of a liquid and homogeneous lotion with a white color and a rose odor. The pH of the preparation was around 5.2-6.5 with a viscosity between 1200-1800 cps. F3 is the best lotion formula based on physical evaluation during four weeks of storage with a composition of 7.5% white dragon fruit extract, 1% glycerin, 0.05% triethanolamine, 3% liquid paraffin, 0,3% methyl paraben, 2% dimethicone, 2% stearyl alcohol, 1.5% glycerol monostearate, 3% virgin coconut oil, 0.1% disodium edetate, 3% cetyl alcohol, 0.2% titanium dioxide, parfum qs, and aquadest ad 100%.
Strategi Komunikasi dan Peran BPOM dalam Menghadapi Produk Bahan Alam Ilegal Yusuf, Marsha Afifah; Husni, Patihul; Ratnawati, Aini
Indonesian Journal of Biological Pharmacy Vol 5, No 3 (2025): IJBP (Desember)
Publisher : Department of Biological Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijbp.v5i3.68556

Abstract

Peredaran produk bahan alam ilegal, terutama Obat Tradisional (OT) yang mengandung Bahan Kimia Obat (BKO) terus meningkat di Indonesia, dari 31 kasus pada tahun 2020 menjadi 61 kasus pada tahun 2022. Fenomena ini merupakan tanggung jawab Badan Pengawas Obat dan Makanan (BPOM). Artikel ulasan ini bertujuan untuk menganalisis strategi komunikasi dan peran BPOM dalam menghadapi isu produk bahan alam ilegal. Penelitian ini menggunakan metode tinjauan pustaka (literature review) dengan mengidentifikasi, mengevalusi, dan mensintesis studi dan publikasi resmi BPOM/pemerintah dalam rentang waktu 2015-2025. Hasil analisis menunjukan bahwa peran BPOM sudah komprehensif, mencakup regulasi, pengawasan, dan penindakan. Namun, peningkatan tren kasus produk ilegal yang berulang mengindikasikan bahwa regulasi yang ketat dan upaya penindakan seperti penarikan produk yang rutin dilakukan BPOM pada Juli, Agustus, dan September 2025 belum sepenuhnya efektif. Keberhasilan pengawasan juga bergantung pada kerjasama antar lembaga dan penagak hukum untuk meningkatkan efek jera. Strategi komunikasi BPOM dan BBPOM berfokus pada Komunikasi, Informasi, dan Edukasi (KIE) melalui media daring dan luring. Diperlukan optimalisasi platform regional BBPOM agar informasi resmi dapat bersaing dengan berita palsu. 
Dampak Minor Stoppage terhadap Overall Equipment Effectiveness pada Lini Produksi Sediaan Steril : Tinjauan Literatur Aziz, Calista Sasikirana Finola; Husni, Patihul; Sigalingging, Asima Rohana
Majalah Farmasetika Vol 11, No 3 (2026)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/mfarmasetika.v11i3.70346

Abstract

Industri farmasi, khususnya pada lini produksi sediaan steril, menuntut tingkat mutu dan efisiensi yang tinggi untuk menjamin keselamatan pasien serta memenuhi persyaratan regulasi. Salah satu faktor yang memengaruhi efektivitas produksi adalah penghentian singkat (minor stoppage), yaitu gangguan singkat pada mesin atau lini produksi yang cenderung dapat diatasi dengan intervensi ringan operator. Tinjauan literatur ini bertujuan untuk mengkaji dampak penghentian singkat (minor stoppage) terhadap Efektivitas Keseluruhan Peralatan (Overall Equipment Effectiveness / OEE) pada lini produksi sediaan farmasi steril. Metode yang digunakan adalah tinjauan literatur melalui database Google Scholar, PubMed, dan ScienceDirect. Hasil menunjukkan bahwa minor stoppage termasuk kategori kerugian akibat penurunan kecepatan (speed losses) yang dominan menurunkan komponen kinerja (performance) pada OEE. Meskipun berdurasi singkat, frekuensi kejadian minor stoppage yang tinggi menyebabkan akumulasi kehilangan waktu operasional yang signifikan. Dampak tersebut semakin kompleks pada produksi sediaan farmasi steril karena keterbatasan intervensi operator dan persyaratan lingkungan aseptik. Faktor penyebab minor stoppage dapat berasal dari mesin, manusia, material, dan lingkungan. Pengendalian melalui Pemeliharaan Produktif Total (Total Productive Maintenance / TPM) terbukti efektif menekan gangguan dan meningkatkan OEE. Kesimpulannya, minor stoppage merupakan salah satu penyebab utama penurunan OEE sehingga perlu dikendalikan secara sistematis. 
Duck Egg Shell and Bay Leaf Extracts (Syzygium polyanthum [Wight] Walp.) Toothpaste Development Using Sodium CMC as a Binder ERYANI, MIKHANIA; perwita, tista; aditama, agnis; rashati, dewi; husni, patihul; wijiani, nina
Pharmaceutical Journal of Indonesia Vol. 11 No. 2 (2026)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Background: Toothpaste is a semi-solid preparation that helps shield teeth from bacterial harm by including abrasive compounds and other helpful elements. Duck eggshells are one of the natural materials that contain calcium carbonate as an abrasive, while bay leaves are a plant that hassantibacterial properties. Objectives: This study aims to formulate duck egg shell toothpaste and bay leaf extract (Syzygium polyanthum [Wight] Walp.) with sodium CMC variation concentrations. Methods: toothpaste is formulated with variation CMC concentration are 3% for F1; 4.5% for F2; and 6% for F3 and evaluate its physical properties. The physical properties tests conducted included organoleptic tests, homogeneity, pH, viscosity, spreadability, and foam height. Results: From the research results, there is an effect of varying sodium CMC concentrations on the physical properties of pH, viscosity, spreadability, and foam height, but no effect of varying sodium CMC concentrations on the organoleptic and homogeneity properties. Conclusions: The research indicate that all formulas meet the requirements for the physical property tests of duck egg shell toothpaste and bay leaf extract.
Duck Egg Shell and Bay Leaf Extracts (Syzygium polyanthum [Wight] Walp.) Toothpaste Development Using Sodium CMC as a Binder ERYANI, MIKHANIA; perwita, tista; aditama, agnis; rashati, dewi; husni, patihul; wijiani, nina
Pharmaceutical Journal of Indonesia Vol. 11 No. 2 (2026)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Background: Toothpaste is a semi-solid preparation that helps shield teeth from bacterial harm by including abrasive compounds and other helpful elements. Duck eggshells are one of the natural materials that contain calcium carbonate as an abrasive, while bay leaves are a plant that hassantibacterial properties. Objectives: This study aims to formulate duck egg shell toothpaste and bay leaf extract (Syzygium polyanthum [Wight] Walp.) with sodium CMC variation concentrations. Methods: toothpaste is formulated with variation CMC concentration are 3% for F1; 4.5% for F2; and 6% for F3 and evaluate its physical properties. The physical properties tests conducted included organoleptic tests, homogeneity, pH, viscosity, spreadability, and foam height. Results: From the research results, there is an effect of varying sodium CMC concentrations on the physical properties of pH, viscosity, spreadability, and foam height, but no effect of varying sodium CMC concentrations on the organoleptic and homogeneity properties. Conclusions: The research indicate that all formulas meet the requirements for the physical property tests of duck egg shell toothpaste and bay leaf extract.
Co-Authors Adi Prayitno Aditama, Agnis Agita, Kiva Agnis Pondineka Ria Aditama Ahmad Muhtadi Alicia Ima Dara Ami Tjitraresmi, Ami Anis Yohana Chaerunisaa, Anis Yohana ANUGRAHANI YUNIAR EKAWATI Apriyani, Mila Ardian Baitariza, Ardian Aryani, Annisa Fitri Astri Sherly Inggriani Astri Sherly Inggriani Ayuning Trias, Diah Aziz, Calista Sasikirana Finola Billa Nidia Hikmatiana Budianto, Muhamad Oke Cahya Lestari, Riska Carolina, Theresia Denok Risky Ayu Paramita Dolih Gozali Dwi Puji Astuti Een herliani Erika Herawati, Irma ERYANI, MIKHANIA Eryani, Mikhania Christiningtyas Fakhirah, Maitsa Alya Fakhri Rabbani FARIANTI EKO NUR KHASANAH Fauziah, Neneng Alifia Nur Firmansyah Firmansyah Hazrina, Aghnia Henny Lucida Hery Diar Febryanto Ida Musfiroh -, Ida Musfiroh IRMA RAHAYU LATARISSA Januarti, Melinda Judy Handojo, Kukuh Khanifah Hidayati Puspa Negara Khoirunnisa, Arina Kurniati, Bunga Dian Kusdi Hartono Kusdi Hartono, Kusdi Layyareza, Rania Talinta Luthfiah, Annisa Mayang K. Dewi MEGA HIJRIAWATI Mikhania Christiningtyas Eryani Muhaimin Muhaimin Mulyani, Tuti Sri Muthia Izati NADYA INDAH DEWANTI, NADYA INDAH Nafisa Nurfatia Hidayat Nina Wijiani Norisca A. Putriana NORISCA ALIZA PUTRIANA NUR DIANA HADAD Nuryani, Tri Winarsih Permatasari, Lina Putri Perwira, Anggun Putri perwita, tista Puspitaningrum, Kartika Putri, Refitha Nurul Rashati, Dewi Ratnawati, Aini RESTIKA ERIA PUTRI Rini Hendriani Safitri, Manzil Salsabila, Annisa Siti Sigalingging, Asima Rohana Silvia, Nurfianti Siti Nur Azizah, Siti Nur Sitinjak, Bernap Dwi Putra Soewahju, Renata Bella SORAYA RATNAWULAN MITA, SORAYA RATNAWULAN Syuhuriah, Ainin Taofik Rusdiana Tryani Sutisna Putri, Sussy Vinny Hosiana Widayanti Supraba Yoga Windhu Wardhana Yosita Aulia Mustofa Yuli Agung Prasetyo YUNIKE KARUNIA PUTRI Yusuf, Marsha Afifah