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Hairunisa, Nany
Department Of Occupational Medicine, Faculty Of Medicine, Universitas Trisakti, Jakarta, Indonesia
Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Social Sciences Transportation Veterinary Other

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Review: penyakit virus corona baru 2019 (COVID-19) Nany Hairunisa; Husnun Amalia
Jurnal Biomedika dan Kesehatan Vol 3 No 2 (2020)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2020.v3.90-100

Abstract

Sebuah virus corona baru diidentifikasi sebagai SARS-CoV-2, pertama kali teridentifikasi di Wuhan, Cina, pada Desember 2019 dan dikenal dengan nama COVID-19. Memiliki 85% homologi dengan SARS-CoV, S-protein pada virus ini akan mengikat reseptor target (ACE2) pada manusia terutama pada paru, jantung, dan ginjal. COVID-19 memiliki masa inkubasi lebih lama dan penularannya lebih tinggi. Penularan terjadi melalui droplet saluran nafas dan kontak erat dengan penderita. Pandemi terjadi dengan sangat cepat, hingga 19 Mei 2020 telah teridentifikasi 4.943.077 kasus dengan angka kematian 321.998 orang dari 212 negara. Gejala yang paling sering muncul adalah demam, fatique, batuk kering, myalgia, dan sesak. Tingkat keparahan penyakit meningkat pada lansia dan penderita dengan komorbid (penyakit jantung, diabetes melitus, penyakit paru kronis, hipertensi, dan kanker). Infeksi ini memiliki CFR sebesar 2.3% dan komplikasi yang paling sering menyebabkan kematian adalah komplikasi pada jantung dan paru. Hingga saat ini belum ditemukan pengobatan yang tepat maupun vaksin untuk penyakit ini, namun penelitian guna pengembangan pengobatan dan vaksin terus dilakukan di seluruh dunia. Upaya maksimal harus dilakukan karena wabah ini mempengaruhi infrastruktur kesehatan publik, ekonomi, dan seluruh aspek di semua negara di dunia. Tindakan pencegahan adalah sangat penting sebagai upaya memutus mata rantai penularan COVID-19.
Di masa COVID-19, bagaimana cara melindungi diri sendiri dan orang lain? Angham G Hadi; Mohammed Kadhom; Emad Yousif; Nany Hairunisa
Jurnal Biomedika dan Kesehatan Vol 3 No 3 (2020)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2020.v3.153-158

Abstract

Coronaviruses are a big identified group of viruses that could result in sickness in humans and animals. It was confirmed that many of these viruses caused respiratory diseases among humans and their symptoms range from popular colds to more serious diseases, such as the Middle East respiratory syndrome (MERS) and severe acute respiratory syndrome (SARS). The recently detected Coronavirus (called SARS-CoV-2) causes the COVID-19 pandemic, which causes a serious threat worldwide. There was no previous knowledge of this virus before the outbreak of Wuhan city in China in December 2019. However, there is progress in defining, understanding and dealing with this virus. In this review, we are focusing on the common questions regarding coronavirus transition and spread, and how to prevent the infection.
Occupational Health During the Covid-19 Pandemic Nany Hairunisa
Jurnal Biomedika dan Kesehatan Vol 5 No 1 (2022)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2022.v5.1-3

Abstract

Despite the significant global burden of COVID-19, the current pandemic has resulted in unprecedented economic hardship. When various business fields are trying to reopen during the present coronavirus disease (COVID-19) pandemic, industrial hygiene (IH), occupational health and safety (K3) are being challenged to be able to assess and manage COVID-19 risks in the workplace. In general, many measures have been designed to control workplace hazards; however, efforts to adapt them specifically to prevent infectious disease outbreaks are still limited. All employers should remain alert and informed about changing outbreak conditions, including the spread of the virus in the community and the availability of testing, and implement appropriate infection prevention and control measures. For this reason, the government and employers need to prepare workers to return to work safely and safely with preventive measures to help reduce the transmission of the virus, especially in the workplace.
Review: Pengaruh Nanopartikel ZnO sebagai Antimikroba pada Multidrug Resistance Klebsiella Pneumonia Nuha Kudaer; Mohsen Hashim Risan; Emad Yousif; Mohammed Kadhom; Rasha Raheem; Nany Hairunisa; Husnun Amalia
Jurnal Biomedika dan Kesehatan Vol 5 No 3 (2022)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2022.v5.236-242

Abstract

Klebsiella pneumoniae (K. pneumoniae)is a common microorganism for different infections, including respiratory, urinary tract, and biliary diseases, where immunocompromised individuals are directly affected by this bacterium. However, with the emergence of hypervirulent strains, individuals,whether healthy or immunocompetent, are equally susceptible to K. pneumoniae infections. This problem is diagnosed by the wide spreading of multidrug-resistant bacteria in the environment with multiple resistance mechanisms, which are the main challenges for an effective treatment. This put physicians in an inflexible confusion because of the limitation of medical treatment options. Among many remedy substances, zinc oxide (ZnO) nanoparticles (NPs) showed remarkable antibacterial properties versus many Gram-positive and Gram-negative bacteria. This work focuses on presenting the influence of these NPs on the expression of genes in charged in generating the K. pneumoniae capsule. Furthermore, perspectives for applying ZnO NPs in clinical practices are also discussed. As the in vivo studies show a powerful impact of ZnO on bacteria, it is anticipated that this method of treatment will be utilized by hospitals.
DETEKSI DAN PENYULUHAN PENYAKIT AKIBAT KERJA PADA PENGUPAS KERANG HIJAU DI CILINCING, JAKARTA UTARA Amalia, Husnun; Hairunisa, Nany; Mashabi, Yasmine; Zaina, Nashita Amira
Jurnal Abdi Masyarakat Indonesia (JAMIN) Vol 6 No 2 (2024): JURNAL ABDI MASYARAKAT INDONESIA (JAMIN)
Publisher : Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jamin.v6i2.17861

Abstract

DKI Jakarta is the most populous city in Indonesia and 59.29% of North Jakarta's population are fishermen, and Cilincing is the largest producer of green mussels in DKI Jakarta with 286 green mussel fishermen (2010), which is 70% of the total number of green mussel fishermen of DKI Jakarta and involves around 1,200 workers. The professions of the community are fishermen and clam collectors (25%), shellfish peel workers (8%), and shellfish traders (6%). The profession of shelling shells is carried out less ergonomically for 6-8 hours a day. This can lead to occupational diseases including Low Back Pain, Frozen shoulder, trigger finger, and the threat of chemical hazards. This service activity aims to detect occupational diseases in green mussel peeling workers and provide preventive information so that the disease does not occur. The consultation and examination activities were attended by 87 residents, aged from 5-84 years. Occupational diseases are mainly found in residents who are still actively working in the Green mussel peeling industry. Occupational diseases are found to be fit for duty in this industry. The lifting officer seemed to lift less ergonomic activities so that abnormalities of Hernia Nucleus Purposus (HNP), myalgia Shoulder pain, and Low Back Pain (LBP) were detected. Scallop peelers complain of low back pain (LBP), neck pain, and Carpal Tunnel Syndrome (CTS). Counseling participants are women working as green mussel peelers aged 20-73. The duration of working hours per day > 5 hours (92.3%). Education level is low (76.9%) and length of work experience varies between 1->30 years. Counseling showed good results, judging from the post-test scores 100% of participants showed good results. Workers need follow-up from various parties to prevent occupational diseases in green mussel peeling workers.
EDUKASI PERSONAL HYGIENE PADA PEKERJA PENANGANAN PRASARANA DAN SARANA UMUM (PPSU) Lestari, Ade Dwi; Ridwan, Alvin Mohamad; Hairunisa, Nany; Khairani, Rita; Khairunisa, Adinda; Kencana, Gita; Iskandar, Dian
Jurnal Pengabdian Masyarakat Trimedika Vol. 2 No. 2 (2025)
Publisher : Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/abdimastrimedika.v2i2.22920

Abstract

Personal hygiene is a crucial component of occupational health, particularly for sanitation workers, including Public Infrastructure and Facility Handling (PPSU) workers in Rawa Buaya Village. This community service project aimed to provide education and assess the knowledge and awareness of PPSU workers regarding personal hygiene, with a focus on handwashing. The activity included counseling sessions, pre- and post-tests, and the distribution of educational materials such as posters and presentations. The results showed a significant improvement in workers' knowledge, with an average post-test score increase of 37.68%. These findings highlight the importance of continuous occupational health education to enhance hygiene practices and reduce health risks among PPSU workers
Survei Pola Kuantitas Peresepan Antibiotik di Tiga Rumah Sakit di Indonesia dengan Penatagunaan Antimikroba Digital Natadidjaja, Ronald Irwanto; Lekok, Widyawati; Ariyani, Aziza; Adlani, Hadianti; Adianto, Raymond; Maharani, Ronaningtyas; Sumarsono, Hadi; Yenny, Yenny; Samira, Jihan; Hairunisa, Nany; Amalia, Husnun; Faradila, Meutia Atika; Fadilah, Tubagus Ferdi; Kalumpiu, Joice Viladelvia; Yuliana, Yuliana; Mulyani, Sri; Anggiat, Desi; Marja, Triyoko Septio; Pertiwi, Iin Indra; Dianawati, Dianawati; Legoh, Grace Nerry; Rantung, Alvin Lekonardo
Jurnal Biomedika dan Kesehatan Vol 8 No 2 (2025)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background Antimicrobial Stewardship Program (ASP) is very essential. There are three categories of antimicrobial agents as recommended by WHO: Access, Watch and Reserve. e-RASPRO, a digital ASP model, may alter antibiotic prescribing patterns by prioritizing Access category antibiotic prescribing. Methods Our manuscript presented a quantitative survey on antibiotic prescribing patterns within 3 months and 9 months before and after implementing digital electronic-RASPRO (e-RASPRO) in three Indonesian hospitals, utilizing retrospective inpatient data. This analysis included the appropriateness of empirical antibiotic prescribing and the quantity of antibiotic prescribing based on each category. Results In the first 3 months, we found that 90.16%, 83.98%, and 81.15% of patients were included in Type 1 Risk Stratification. The appropriateness of initial empirical antibiotic prescribing with the digital guideline on antimicrobial use of e-RASPRO in three hospitals was 81.59%, 76.09% and 24.48%, respectively. Within 9 months after implementing e-RASPRO in Hospital A and B and within 3 months in Hospital C, there was a trend of reduced quantity of Watch category antibiotic prescribing of 54.93% (-58.86% per inpatient), 21.11% (-9.97% per inpatient), and 8.59% (-4.15% per inpatient), respectively. There was a 12.42% (+2.61 % per inpatient) and 223.17% (+268.83% per inpatient) increase in the quantity of Access category antibiotic prescribing in Hospitals A and B, while in Hospital C, the quantity decreased by 6.81% (-2.29% per inpatient).   Conclusions There are changes in antibiotic prescribing patterns, particularly in the antibiotics included in the Watch and Access categories following the implementation of e-RASPRO. The relationship between digital antimicrobial stewardship use and the results still needs further research.
Deteksi gen secara Epidemiologi Molekuler pada Isolat Klinik Klebsiella pneumoniae dari Pasien Dewasa dengan komorbid di Rumah Sakit Baghdad Kudaer, Nuha B; Risan, Mohsen Hashim; Raheem, Rasha; Zainulabdeen, Khalid; Salman, Israa; Hairunisa, Nany; Amalia, Husnun; Hameed, Seenar; Yousif, Emad
Jurnal Biomedika dan Kesehatan Vol 6 No 2 (2023)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2023.v6.196-215

Abstract

Background Klebsiella species is one of the most worldwide opportunistic pathogens in the world that cause infections at multiple sites like lung, urinary tract, bloodstream, wound or surgical site, and brain. Klebsiella pneumoniae has many types of virulence factors that give the bacteria the ability to invade the host and cause infections. Methods A total of (105) human clinical samples were collected from different patients with different cases. Klebsiella pneumonia were isolated from 30 samples. The bacteria were identified by biochemical tests and certified by using VITEK 2 system and genetically by amplify using PCR for 16 rRNA gene. One of the Klebsiella pneumoniae virulence factors is the capsule that is responsible for the macrophage resistance and its also responsible for serotype. So to confirm the strains isolated, PCR Gene detection of, MagA, K2A, RmpA, and Kfu, where (magA, k2A, rmpA, kfu) gens are responsible for capsule synthesis of Klebsiella pneumonia have been done. Results There were 30 strains of Klebsiella pneumoniae were identified. Epidemiological studies show that infections are preceded by gastrointestinal colonization, with the gastrointestinal tract being the most important reservoir for transmission. The primary bacterial isolates were identified based on their cultural, microscopic, and biochemical traits. The API system (API 20E) and VITEK 2 systems were used to confirm the identity of the bacterial isolates. Colony morphology revealed that Klebsiella pneumonia was Gram-negative, non-motile, microscopic straight rods grouped singly or in pairs. Biochemical tests showed that neutral end products prevailed over acidic end products, with Klebsiella producing negative results for indole. The Kligler Iron Agar (KIA) test showed that Klebsiella isolates changed the color of the slant and butt, producing an acidic slant and acid butt, along with gas production. The urease test for Klebsiella distinguishes between Enterobacter and Klebsiella isolates, as Klebsiella can manufacture the urease enzyme. The indole test distinguishes K. pneumonia from K. pneumonia from K. mobiliz. The API 20E system was used for biochemical testing, and the VITEK 2 system was used for identification. The VITEK 2 system was used to test for biochemical and antibiotic susceptibility, and the results supported the findings from morphological and biochemical analyses. PCR amplification was used for molecular detection, and all nine isolates tested positive for the magA and k2A genes. The ferric iron uptake system gene (kfu) and the extracapsular polysaccharide synthesis regulator gene (rmpA) were amplified using specific primer pairs. The VITEK 2 system demonstrated promising outcomes for K. pneumoniae identification. However, standard diagnostic methods are costly and time-consuming. Conclusions Navigating the complex landscape of infectious diseases, collaborative research projects have become indispensable in unraveling the mysteries surrounding pathogens. The project in Baghdad, having stood as a shining example of such collaboration, provided valuable insights into the identification, characterization, and molecular aspects of Klebsiella pneumoniae strains. The findings, have not only contributed to the scientific community's understanding of bacterial infections but also paved the way for enhanced strategies in diagnosis and treatment.
Studi Faktor-Faktor yang Berhubungan dengan HIV pada Perempuan di Kalimantan Barat, Indonesia Hairunisa, Nany; Sabrina, Isra; Amalia, Husnun; Mashabi, Yasmine; Zaina, Nashita Amira; Yousif, Emad
Jurnal Biomedika dan Kesehatan Vol 6 No 1 (2023)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2023.v6.89-107

Abstract

Background According to national data, West Kalimantan is one of the ten top provinces that reported AIDS cases, ranked eighth. Until December 2019, based on data recorded in the Provincial Health Office that reported to the Indonesia Ministry of Health, the AIDS case rate in West Kalimantan was 49.35, showing over the national AIDS case rate (38.93). In this study, an unmatched case-control determines the factors associated with HIV/AIDS among women in West Kalimantan, Indonesia. Methods The study was conducted among 90 women who tested positive for HIV/AIDS (cases) and 90 who tested negative for HIV/AIDS (controls). Data were collected using questionnaires from June 2019 to August 2019 at three community health centres in West Kalimantan. Data were analyzed using IBM Statistical Package Social Science (SPSS) 19. Descriptive analyses and Multivariate logistic regression analysis were used to examine the factors associated with HIV/AIDS. Results: This study has found a significant association between crucial aspects such as marital status, occupation, knowledge about HIV/AIDS, HIV treatment, and VCT (Voluntary Counseling and Testing) service program with cases of HIV/AIDS. A significant association between marital statuses with HIV/AIDS suggests that divorced/widowed have a higher risk of having HIV/AIDS, followed by the married group. Women with good educational backgrounds will likely know how to prevent HIV infection and take preventive measures to protect themselves. Results This study found a significant relationship between several important aspects such as marital status, occupation, knowledge of HIV/AIDS, HIV treatment, and the VCT (Voluntary Counseling and Testing) service program with HIV/AIDS cases. The significant relationship between marital status and HIV/AIDS shows that divorced/widows have a higher risk of contracting HIV/AIDS, followed by the married group. Women with a good educational background tend to know about HIV infection prevention measures and take precautions to protect themselves. Conclusions Some factors are significantly related to HIV/AIDS. Thus, educating women about sex could potentially decrease the number of HIV/AIDS cases.
Studi Banding tentang pengembangan vaksin untuk COVID-19 Alsayed, Raghda; Zainulabdeen, Khalid; Salman, Israa; Hairunisa, Nany; Amalia, Husnun; Yusop, Rahimi M; Redwan, Amamer M; Yousif, Emad
Jurnal Biomedika dan Kesehatan Vol 6 No 1 (2023)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2023.v6.127-132

Abstract

The human respiratory system can be infected with coronaviruses (CoVs), one of the families of viruses that can lead to symptoms ranging from mild to fatal. Seven genera of CVS have been identified as having human infection to date. The virus can spread as fine, liquid particles from the mouth or nose of an infected person when coughing, sneezing, speaking, or breathing. The diameter of droplet particles ranges from large to small. In this review, we summarize vaccine development for COVID-19. We anticipate this study will be a valuable resource for any researcher interested in creating a COVID-19 vaccine.
Co-Authors Abikusno, Revalita Adhiwardan, Anggraeni Adianto, Raymond Adlani, Hadianti Agil, Nadifa Ahmed, Dina Alsayed, Raghda Alvin M. Ridwan Anastasya, Karina Shari Anggiat, Desi Angham G Hadi Ariyani, Aziza Aswar, Andini Briliant, Permaisonya Cylla Revata David Tjahyadi dianawati, dianawati Djebli, Noureddine Dwi Lestari, Ade Emad Yousif Emad Yousif Eric Fahed Faza Erlani Kartadinata, Erlani Fadlyah, Nur Ashfiya Faradila, Meutia Atika Florinda Ilona Gerie Amarendra Grace Nerry Legoh Hadi Sumarsono Hameed, Seenar Hari Krismanuel Hosea Jaya Edy Husain, Amani Husnun Amalia Irmiya Rachmiyani Isahak, Marzuki bin Iskandar, Dian Joice Viladelvia Kalumpiu, Joice Viladelvia Julian Chendrasari Kadhom, Mohammed Karina Shari Anastasya Kencana, Gita Khairunisa, Adinda Kudaer, Nuha B Larasari, Andira LEKOK, WIDYAWATI Lestari, Ade Dwi Lie T. Merijanti Lie Tanu Merijanti, Lie Tanu Liman, Patricia Budihartanti Magdalena Wartono Maharani, Ni Putu Radela Maharani, Ronaningtyas Mahdi, Sarah Mario Mario Marja, Triyoko Septio Mashabi, Yasmine Meiriani Sari Meiyanti Meiyanti, Meiyanti Mohamad Ridwan, Alvin Mohammed Kadhom Mohammed Kadhom Mohsen Hashim Risan Mulia Rahmansyah Natadidjaja, Ronald Irwanto Nugroho Abikusno Nuha Kudaer Oladimeji, Ashaolu Victoria Parwanto, Edy Patricia Budihartanti Liman Pertiwi, Iin Indra Pramesti Indri Miranti Prasetyaningsih, Noviani Primandari, Rima Anindita Purnamawati Tjhin Purnamawati Tjhin, Purnamawati Pusparini Pusparini Raheem, Rasha Rantung, Alvin Lekonardo Rasha Raheem Redwan, Amamer M Ridwan Harrianto Ridwan, Alvin Mohamad Ridwan, Alvin Muhamad Rima Anindita Risan, Mohsen Hashim Rita Khairani, Rita Sabrina, Isra Salman, Israa Samira, Jihan Setyaningrum, Dyah Ayu Woro Sri Mulyani Sudarma, Verawati T, Febrina Thamer, Hamsa Tjahjadi, Muljadi Tjam Diana Samara Tubagus Ferdi Fadilah, Tubagus Ferdi Verawati Sudarma Wawan Kurniawan Witjaksana, Riani YENNY YENNY Yousif, Emad Yudhisman Imran Yuliana Yuliana Yusop, Rahimi M Zaina, Nashita Amira Zainulabdeen, Khalid