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All Journal Jurnal Anestesiologi Indonesia JBIO: jurnal biosains (the journal of biosciences) Public Health of Indonesia Molecular and Cellular Biomedical Sciences (MCBS) Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat Journal of Epidemiology and Public Health Indonesian Journal of Medicine Journal of Maternal and Child Health Callosum Neurology Journal : Jurnal Berkala Neurologi Bali Jurnal Respirologi Indonesia Oto Rhino Laryngologica Indonesiana Jurnal Respirasi (JR) Sumatera Medical Journal Medika Kartika : Jurnal Kedokteran dan Kesehatan Jurnal Prima Medika Sains Respiratory Science Jurnal Impresi Indonesia Prosiding Konferensi Nasional PKM-CSR Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara The Journal of Society Medicine (JSOCMED) MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation Cermin Dunia Kedokteran

Putri Chairani Eyanoer, Putri Chairani

Department Of Publich Health Faculty Of Medicine, Universitas Sumatera Utara

Author-ID : 555559

Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Neutrophyl Lymphocyte Ratio in Tuberculosis Patients and Multi Drug Resistant Tuberculosis Patients Delores Elisabeth Sormin; Parluhutan Siagian; Bintang YM Sinaga; Putri Chairani Eyanoer
Jurnal Respirologi Indonesia Vol 38, No 3 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Background: Delayed in diagnosis and treatment of tuberculosis will increase the risk of MDR TB. WHO recommends Xpert MTB/RIF as diagnostic tools to identify MDR TB. Availability of Xpert MTB/RIF is still limited, another diagnostic tool is needed. Neutrophyl lymphocyte ratio (NLR) was presumed to be able to identify the probability of MDR TB. The aim of this study is to evaluate the comparison of NLR in tuberculosis and MDR TB patients. Methods: This is an analytic descriptive study with case series approach in Adam Malik General Hospital Medan. This study held since January – December 2015 with number of sample as much as 100 bacteriological confirmed TB patients and 100 MDR TB patients. We performed leukocyte differential count from peripheral blood examination to obtain NLR Result: Mean NLR of TB patient 4.62±2.37 and MDR TB 3.28±1.44. There was significant difference of NLR between both groups using Mann-Whitney test (P=0.001). The cut off value by ROC analysis was 2.91 with sensitivity, specificity, positive predictive value, negative predictive value and accuracy was 77%, 50%, 60.6%, 68.4% and 63.5% respectively. Conclusion: There was significant difference of NLR between bacteriological confirmed TB patients and MDR TB patients. Value of NLR

Pleura Fluid Leukocyte Levels Test in Establish of Pleura Tuberculosis Effusion in Exudative Pleural Effusion Patients at H. Adam Malik General Hospital Medan in 2018 Selvy Wulandari; Fajrinur Syahrani; Ade Rahmaini; Putri Chairani Eyanoer
Jurnal Respirologi Indonesia Vol 41, No 3 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i3.182

Background: Tuberculous pleural effusion is an accumulation of fluid in the pleural cavity produced by Mycobacterium tuberculosis (MTB). The gold standard of TB pleural effusion diagnosis is to obtain TB bacilli in pleural fluid or pleural tissue. However, this is often constrained due to the low identification level of these bacilli and the slow growth of MTB cultures. This study aimed to assess the pleural fluid leukocyte level in establishing a diagnosis of pleural effusion caused by TB. Methods: This was a diagnostic study conducted on 111 patients with pleural effusion, caused by TB, malignancy or non-TB infections that were assigned by supporting examinations obtained from medical records, which then assessed for pleural fluid leukocytes. Statistical analysis was performed using Kruskal Wallis Test and Receiver Operating Characteristic (ROC) curve to attain the cut-off point of pleural fluid leukocyte level. Results: Pleural fluid leukocyte levels in TB cases were significantly different when compared to pleural effusion caused by malignancy and non-TB infections (P<0.001). Pleural fluid leukocyte level ≥1100 cell/mm3 was a cut-off diagnostic test for tuberculous pleural effusion with a sensitivity of 77% and specificity of 60.3%. Conclusion: Pleural fluid leukocyte level ≥1100 cell/mm3 could assist in diagnosing tuberculous pleural effusion.

The Effect of Vitamin C Supplementation on Chest X-Rayimprovementin Pulmonary Tuberculosis Patients During Intensive Phase in Medan Budi Jefri; Bintang YM Sinaga; Parluhutan Siagian; Putri Chairani Eyanoer
Jurnal Respirologi Indonesia Vol 40, No 2 (2020)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Backgrounds: Tuberculosis (TB) is still a public health problem in the world.Vitamin C is a water-soluble micronutrient, protects the host from reactive oxygen and reactive nitrogen intermediates generated during mycobacterial infection, involved in the synthesis of collagen, iron transport, and acts as physiological antioxidant. Vitamin C plays role in killing Mycobacterium tuberculosis by fenton reaction. This study was to determine the effect of vitamin C supplementation on chest X-ray (CXR) improvement in pulmonary TB patients during intensive phase. Methods: This was a quasy experimental study with single blind-randomized controlled trial design. Subjects were divided into 2 groups, first group was pulmonary TB patients treated with anti tuberculosis drugs (ATD) plus vitamin C and the second group was treated with ATD plus placebo. This study was conducted in several public health center in Medan City. The subjects were pulmonary TB patients with positive AFB sputum in intensive phase from December 2017 to May 2018. Data were analized using t-test dependent. Results: From 80 total subjects, 53 males (66%) and 27 females (34%). After 2 months of treatment, improvements in CXR images were found in the ATD plus vitamin C group, about 21 subjects (52.5%) had no more lesions on CXR, while the same condition was found on 15 subjects (37.5%) in the placebo group. Conclusion: Vitamin C supplementation in pulmonary TB provided better improvements of CXR images. (J Respir Indo. 2020; 40(2): 82-7)

Correlation of Hemostatic Parameter with Lung Tumor Marker in Non-Small Cell Lung Cancer Patient with Chemotherapy Ganda M. Leonard Samosir; Parluhutan Siagian; Putri Chairani Eyanoer
Jurnal Respirologi Indonesia Vol 38, No 1 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v38i1.137

Backgrounds: There is a subclinical activation of coagulation and ﬁbrinolysis system in patient with lung cancer. Alterations in hemostatic system are seen frequently in lung cancer correlated with the prognosis of disease. In oncology practice, the use of tumor markers may be helpful in the diagnosis and pathologic classification of tumors. Tumor marker may reflect both, stage of the disease and prognosis. Aim of this research is to asses the correlation of this parameters in patient non-small cell lung cancer with chemotherapy. Methods: This research is an analytic observational with a cross sectional design. The research was conducted at RSUP Haji Adam Malik, Medan from January 1, 2015 to May 31, 2016. Blood test examination was performed to measure the hemostatic parameter (PT, INR, APTT, TT, D-dimer) and serum tumor marker (CEA, Cifra21-1, NSE) of 41 non-small cell lung cancer patients before first cycle of chemotherapy and after fourth or sixth cycles of chemotherapy. Results: The study comprised 41 patients of non-small cell lung cancer (31 adenocarcinoma, 10 squamous cell carcinoma), There were 35 men (85,4%) and 3 women (14,6%) with mean age of 56,7 years. For all patients, we give a platinum based therapy as first line chemotherapy (gemsitabine and carboplatin regimen in 27 patients, paclitaxel and carboplatin in 10 patients, vinorelbine and carboplatin in 4 patients). There is no significant difference of hemostatic parameter and serum tumors marker values before chemotherapy againts after chemotherapy values. And there is a weak negative correlation of hemostatic parameter againts serum tumor marker on non-small cell lung cancer patients with chemotherapy. Conclusion: There is a weak negative correlation of hemostatic parameter againts serum tumor marker in non-small cell lung cancer patients with chemotherapy. (J Respir Indo 2018; 38(1): 33-38)

Hubungan merokok dengan gangguan pendengaran akibat bising pada pekerja pabrik kelapa sawit X Maesyara Adinda Sari; Adlin Adnan; Delfitri Munir; Putri Chairani Eyanoer
Oto Rhino Laryngologica Indonesiana Vol 47, No 2 (2017): Volume 47, No. 2 July - December 2017
Publisher : PERHATI-KL

Latar belakang: Paparan bising dapat mengakibatkan kerusakan pada organ korti, dan menurunkan aliran darah koklea yang mengakibatkan hipoksia koklea. Merokok diketahui sebagai ototoksik langsung dan pemicu iskemia koklea. Kebiasaan merokok dan paparan bising secara sendiri ataupun secara bersama-sama dapat menyebabkan gangguan pendengaran. Tujuan: Mengetahui hubungan merokok terhadap kejadian gangguan pendengaran akibat bising (GPAB). Metode: Penelitian analitik dengan pendekatan potong lintang. Hasil: Dari 122 pekerja, didapati sebanyak 89,3% pekerja mengalami GPAB. Tuli ringan paling banyak ditemukan (68,8%). Didapatkan adanya hubungan yang signifikan antara tipe perokok dengan derajat beratnya GPAB (p=0,000). Kemungkinan pekerja yg merokok untuk mengalami GPAB 1,224 kali lebih besar dibandingkan dengan pekerja yang tidak merokok (PR=1,224, p=0,002, CI 95%=1,077–1,392). Kesimpulan: Terdapat hubungan yang signifikan antara kebiasaan merokok dengan kejadian GPAB.Kata kunci: Merokok, gangguan pendengaran, gangguan pendengaran akibat bising, bising lingkungan kerja ABSTRACT Introduction: Noise exposure can lead to the organ of corti damage, and decrease the blood flow to the cochlea resulting in cochlear hypoxia. Cigarette smoking could be ototoxic to cochlea, and could evoke cochlear ischemia. Cigarette smoking habit and noise exposure, each or together can cause hearing loss. Objective: To identify the correlation between cigarette smoking and noise induced hearing loss (NIHL). Method: Analytic with a cross-sectional study. Results: From the 122 workers, we found that the proportion of NIHL was 89.3%. Mild deafness was most common (68.8%). We found that there was a significant correlation between type of smokers and grade of hearing loss (p=0.000). Workers who smoked likely to undergo NIHL 1.224 times greater than nonsmokers (PR=1.224, p=0.002, CI 95%=1.077–1.392). Conclusion: There was a significant correlation between cigarette smoking habit and noise induced hearing loss.Keywords : Cigarette smoking, hearing loss, noise induced hearing loss, occupational noise exposure

The Effect of Two-Mile Jogging Training on Lung Function Values in TNI Soldier Kodam I/Bukit Barisan Rifda Hayati; Nuryunita Nainggolan; Amira Permatasari Tarigan; Putri Chairani Eyanoer
Respiratory Science Vol. 1 No. 1 (2020): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v1i1.8

Background: Military soldiers are army personnel who are required to have good physical endurance and optimal fitness, include. So, it's needed physical exercise, include to be able to improve lung function. One parameter that can reflect physical fitness are lung function and m VO2max. This study aims to determine whether there is a relationship between physical exercise in the form of 2-mile jogging with increased lung function and VO2max of military soldiers Kodam 1 Bukit Barisan Methods: This research is an experimental study carried out in February-April 2019 against the TNI soldiers of the Bukit Barisan Military District 1. The research subjects were divided into two groups, group 1 who underwent regular 2-mile jogging exercises 3-5 times a week with a duration of 25 minutes for 2 months, and group 2 who underwent non-routine jogging exercises (less than 3 times a week). Lung function was assessed by spirometry. Results: As many as 68 military soldiers were involved in this study which were divided into two groups, 38 people in the group 1 who routinely trained and 30 people in group 2 that did not routinely practice. Group 1 VEP1 values were higher than group 2 (p=0.03). No significant differences in terms of KVP, MVV and VO2max in both groups. Lung function of smokers were lower than non-smokers, but not statistically significant. Conclusion: There were significant differences in VEP1 values between military soldiers who routinely and did not routinely undergo 2-mile jogging exercises.

Accuracy Between CURB-65 Score and PSI in Determining The Prognosis of Community-Acquired Pneumonia Patients at H. Adam Malik General Hospital, Medan Fransisco Sentosa Pakpahan; Syamsul Bihar; Fajrinur Syarani; Putri Chairani Eyanoer
Respiratory Science Vol. 1 No. 3 (2021): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v1i3.25

Background: Community-Acquired Pneumonia (CAP) is an important problem associated with morbidity and mortality. An accurate initial assessment is required before starting management of a CAP patient to determine the prognosis of the patient as early as possible. The CURB-65 score and PSI (Pneumonia Severity Index) are initial assessment scores that can be used. This study aimed to compare the accuracy between the CURB-65 score and the PSI in determining the prognosis in CAP patients at H. Adam Malik General Hospital Medan. Method: A descriptive study was conducted on 76 patients diagnosed with CAP. Each patient was assessed for their CURB-65 score, PSI class and mortality within 30 days of admission. Data were collected through patient medical records diagnosed CAP in 2018 and performed statistical analysis using 2x2 tables. Results: The CURB-65 ≥3 score showed accuracy (71.0%), sensitivity (53.8%), and specificity (89,2%). The CURB-65 ≥ 2 score showed accuracy (75.0%), sensitivity (82.1%), and specificity (67.6%). Meanwhile, the Class IV-V PSI showed accuracy (77.6%), sensitivity (87.2%) and specificity (67.6%). Conclusion: The accuracy of the PSI is higher when compared to the CURB-65 score in determining the prognosis of CAP patients at H. Adam Malik General Hospital Medan. Although PSI is more accurate, CURB-65 is simpler, easier and less expensive to use

CT Guided TTNA and Core Biopsy in Suspected Lung Cancer, Review of Cases in Adam Malik General Hospital, Medan Hadi Suhendra; Fajrinur Syarani; Syamsul Bihar; Putri Chairani Eyanoer
Respiratory Science Vol. 2 No. 1 (2021): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v2i1.27

ounds: The cytological and histopathological findings establish the type of lung cancer cells as the definitive diagnosis of lung cancer. This study aimed to determine the characteristics of lung cancer patients in terms of age, mean age, gender, staging, the proportion of lung cancer cells by cytologic examination of Transthoracic Needle Aspiration (TTNA) and histopathologic evaluation from CT-guided core biopsy. Method: This is a descriptive study involving 42 subjects diagnosed with lung cancer at H. Adam Malik Hospital Medan in 2016-2020 that met the inclusion criteria through consecutive sampling. Data was analysed using descriptive statistics for categorical variables. Results: Of 42 study subjects, the 60–71-year age group had the highest percentage of lung cancer (42.9%). Male (71.4%) was higher than female, the most common lung cancer staging was IVA (57.1%), and adenocarcinoma was found to be the most frequent type of lung cancer in both cytology (33.3%) and histopathology (31.0%). Conclusion: We concluded that core biopsy is superior in diagnosing lung cancer compared to TTNA.

Vitamin C Supplementation Improves Pulmonary Tuberculosis Patients' Sputum Conversion During Intensive Phase Category I Treatment in Medan Elok Ariyani Safitri; Parluhutan Siagian; Bintang Yinke Magdalena Sinaga; Putri Chairani Eyanoer
Respiratory Science Vol. 2 No. 2 (2022): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v2i2.30

Background: Many factors influence the success of the acceleration of Acid-Fast Bacilli (AFB) sputum conversion in the treatment of the intensive phase of pulmonary tuberculosis (TB). One of these factors is the nutritional status or nutrition of pulmonary TB patients. Through a fenton reaction, Vitamin C is known to be able to sterilize Mycobacterium tuberculosis. This study aims to determine the effect of giving vitamin C on the conversion of AFB sputum in the intensive phase of pulmonary TB treatment. Method: This study was an inferential, quasi-experimental evaluation of the acceleration of AFB sputum conversion following vitamin C supplementation in patients with category I pulmonary TB. The study group was separated into two groups: 40 TB patients getting Anti Tuberculosis Treatment (ATT) with vitamin C, and 40 TB patients receiving ATT with placebo. Every two weeks, AFB sputum was examined, and vitamin C levels were measured before and after two months of therapy. Results: Conversion of AFB occurred sooner in the vitamin C group of pulmonary TB patients, with as many as 29 patients (72.5%) experiencing conversion of AFB sputum at the end of the second week of therapy, whereas there was no conversion in the placebo group. At the end of the fourth week, all patients (100%) given vitamin C showed AFB sputum conversion, whereas only eight patients (20%) in the placebo group had conversion at the end of the fourth week of treatment. Vitamin C levels increased significantly in the group of pulmonary tuberculosis patients who received vitamin C supplementation. Conclusion: Vitamin C supplementation in the treatment of pulmonary TB can accelerate the conversion of AFB sputum, which is statistically significant.

The Associations Between Severity Of Symptoms, D-Dimer and Incidence of ARDS In COVID-19 Herani Mutia Riandini; Fajrinur Syaran; Syamsul Bihar; Putri Chairani Eyanoer
Respiratory Science Vol. 2 No. 3 (2022): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v2i3.40

Background: Severe acute respiratory injury caused by COVID-19 (ARDS) is a serious emerging complication. ARDS results from a cytokine storm that occurs in the second week of the disease course and acute-onset hypoxemia can be seen with bilateral infiltrates on chest radiograph. This study aimed to relate the severity of symptoms and D-dimer level to the incidence of ARDS in COVID-19 at H. Adam Malik Hospital as the referral center for COVID-19 in North Sumatra. Method: This was a descriptive study with a retrospective cohort design. The sample of this study was secondary data from medical records of positive RT-PCR COVID-19 patients from November 2020 to April 2021. The inclusion criteria were patients with moderate to critical COVID-19 cases with D-dimer examination taken from the first day of admission. Subjects were then followed up until discharge from the hospital to assess for ARDS episodes which were confirmed by the results of PaO2/FiO2 in arterial blood gases and bilateral infiltrations in chest X-Ray. The exclusion criteria were incomplete medical records. Results: The association between the severity of symptoms and the incidence of ARDS, 1 of which was found to be moderate, 19 cases were severe and 20 were critical. However, there was a statistically significant correlation between the severity of symptoms and the incidence of ARDS (P=0.0001). Conclusion: There was a significant correlation between the severity of symptoms and the D-dimer value on the incidence of ARDS.

Co-Authors -, Fadhlia Ade Rahmaini Adlin Adnan Alona, Ivana Alwi Thamrin Nasution Amaiappan, Jesvinder Amira P. Tarigan Amira Permatasari Tarigan Amira Permatasari Tarigan Andika Pradana Andika Pradana Andika Pradana Arieta, Lydia Arlinda Sari Wahyuni Armon Rahimi Asnir, Rizalina Arwinati Azali, Chairul Nurdin Azizah Ghanie Icksan Bintang Yinke Magdalena Sinaga Bintang Yinke Magdalena Sinaga Bintang YM Sinaga Bintang YM Sinaga Budi Jefri Budi Wiweko Chairiza Muttaqien Dana Jauhara Layali Delfitri Munir Delfitri Munir Delores Elisabeth Sormin Destylya, Dyana Dyana Destylya Eddy Bangun Elisabeth Elisabeth Elizabeth Napitupulu Elmeida Effendy Elok Ariyani Safitri Elva Susanty Elvita Rahmi Daulay Endy Juli Anto Endy Todo Sirait endyjulianto endyjulianto Eva Susanti Debora Hutabarat Evo Elidar Harahap Fachrezi, Muhammad Alfian Fajrinur Syahrani Fajrinur Syahrani Fajrinur Syaran Fajrinur Syarani Fajrinur Syarani Fajrinur Syarani Faradila, Devita Farhat, Farhat Faried, Mukhamad Febiyanti, Mica Felisia Felisia Firdaus, Ruby Fransisco Sentosa Pakpahan Fujiati, Isti Ilmiati Ganda M. Leonard Samosir Ghazali Akhmad Putranta Ginting, Franciscus Hadi Suhendra Hafizhalaila Ammar Hakim, Enggrek Pelita Hamdi, Tasrif Harahap, Juliandi Haryuna, Tengku Siti Hajar Hasibuan, Mangain Hemma Yulfi Hendri Wijaya, Hendri Henny Maisara Sipahutar Herani Mutia Riandini Hidayat Hidayat Ihsan, Mhd. Joshua Asley Juli Anto, Endy Juliandi Harahap Kadri, Alfansuri Kartini harahap Kembaren, Tambar kenvin rusli Kiking Ritarwan Listyoko, Aditya Sri Lubis, Muhammad Allif Syafrin Lubis, Netty Delvrita Maesyara Adinda Sari Muhammad Ichwan Muhammad Zainul A Muntasir Abdullah Nababan, Windika Nasution, Duma Ratna Sari Netty Delvrita Lubis Netty Delvrita Lubis Noni Novisari Soeroso Noni Novisari Soeroso Noni Novisari Soeroso Nurdiansah, Firman Nurul Citta Banu Putri Nurul Ramadhani Nuryunita Nainggolan Octavia, Nur Afni Heryanti Pandia, Pandiaman Pandiaman Pandia Pandiaman Pandia Panjaitan, Alfred Johnatan Pardede, Sujahn Anto Parluhutan Siagian Parluhutan Siagian Parluhutan Siagian Pase, M Aron Pendiaman Pandia Perangin-angin, Gwanita Nawariantina Peter Peter Pratama, Mhd. Rizki Pratiwi, Ade Dwi R.A Henny Anggriani Ramadhani, Adini Arifah Rambe, Andrina Yunita Murni Restuti Hidayani Saragih Ribawanto, Muhammad Rafif Rifda Hayati Rina Amelia Rina Yunita Ririe Fachrina Malisie Risqin, Muhammad Anas Fatah Rosita Juwita Sembiring Salsabila, Anisa Samodra, Yoseph Leonardo Sarah, Dewi Maya Sekali, Oktaviani Karo Selvy Wulandari Siahaan, Jekson Martiar Sikumbang, Rahmat Hidayat Sinaga, Bintang Yinke Magdalena Sinaga, Joshua Princeman Sinaga, Sudirman Parningotan Sirait, Asima Rodiarta Siregar, Nondang Purnama Syamsul Bihar Syamsul Bihar Syamsul Bihar Syarani, Fajrinur Tarigan, Amira Permatasari Tarigan, Setia Putra Tri Setia Negara Sinulingga Vera, Yeni Wahyuni, Arlinda Sari Wan Betty Pratiwi Yahwardiah Siregar Yessi Andriani Zainal Yunanda, Yuki Zainuddin Amir Zakirah, Sarah Chairani

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