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Journal : Current Biomedicine

Hubungan teknik pemerahan dengan jumlah Escherichia coli pada susu segar dari peternakan sapi perah di KUD Kertajaya, Kabupaten Kediri, Jawa Timur Rahadyan, Raihan Alif; Tyasningsih, Wiwiek; Puspitasari, Yulianna; Permatasari, Dian Ayu; Widjiati, Widjiati
Current Biomedicine Vol. 1 No. 1 (2023): January
Publisher : School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/currbiomed.1.1.19-24

Abstract

Background: The coliform bacteria group is a group of bacteria used as an indicator of food sanitation, one of which is in dairy products. Objective: This study aimed to determine the relationship of milking techniques with the number of Escherichia coli in raw milk compared to the bacterial contamination limit set by the National Standardization Agency. Methods: The design of this study was a descriptive study. Raw milk samples were taken from Lucky Farm and several traditional dairy farms in the KUD Kertajaya area, Kediri Regency, East Java. This study uses the most probable number (MPN) test. Results: The results showed 11 (73.3%) of raw milk samples using conventional milking techniques exceeding the maximum limit of E. coli bacterial contamination determined by the National Standardization Agency (< 3 MPN/mL). However, all 15 samples, or 100% of raw milk samples using machine milking techniques, were negative for E. coli and met the maximum bacterial contamination limit requirements. Conclusion: The milking techniques affect E. coli contamination limits in raw milk. The milk samples taken using machine milking techniques had better results with MPN values ​​< 3 MPN/mL than those taken using conventional milking techniques.
Pengaruh Pemberian Nanocurcumin (Curcuma longa) Terhadap Gambaran Histopatologis Pulmo Tikus (Rattus norvegicus) Yang Dipapar Carbon Black Rahmaniabdi, El Roy Achmad; Mustofa, Imam; Hestianah, Eka Pramyrtha; Widjiati, Widjiati; Kurnijasanti, Rochmah; Plumeriastuti, Hani
Current Biomedicine Vol. 3 No. 1 (2025): January
Publisher : School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/currbiomed.3.1.38

Abstract

Background Exposure to carbon black can induce respiratory toxicity, leading to tissue remodeling, inflammation, and fibrosis. Curcumin, a compound from Curcuma longa, has been shown to exert protective effects on lung tissue by inhibiting cell proliferation and reducing alveolar epithelial thickening and inflammatory responses. Objective This study aimed to evaluate the effect of nanocurcumin administration on alveolar septal thickness and fibrosis in the lungs of rats (Rattus norvegicus) exposed to carbon black. Methods Thirty female rats were divided into five groups: the negative control group (K-) received distilled water without carbon black exposure; the positive control group (K+) received distilled water and was exposed to carbon black at a dose of 1064 mg/m³ for 6 hours; and treatment groups P1, P2, and P3 received nanocurcumin at doses of 50, 100, and 200 mg/kg body weight, respectively, along with carbon black exposure at a dose of 1064 mg/m³ for 6 hours/day over 30 days. Results Alveolar septal thickness and fibrosis in the P1, P2, and P3 groups showed significant reductions (P<0.05) compared to the K+ group. Notably, groups P2 and P3 exhibited similar alveolar septal thickness to the K- group, with statistically lower (P<0.05) fibrosis levels than P1 but not significantly different from K- (P>0.05). Conclusion Nanocurcumin administration demonstrates potential in mitigating alveolar septal thickening and fibrosis in rat lungs subjected to carbon black exposure, suggesting a protective role against pulmonary damage from particulate matter.
Co-Authors Achmad Salman Faridz, Achmad Salman Agung Budianto Achmad, Agung Budianto Agustina, Widayati Alfiah Hayati Aliyah, Suhartatik Amila, Ukhti Mukminah ilmi Annise Proboningrat Ardy, Carolina Arimbi Askandar Tjokroprawiro Bambang Poernomo Berlina, Cyrcilia Relita Budi Wicaksono Chairul Anwar Darsono, Roesno Dewita Dewita Dwi Gustin, Mandasari Eighty Mardiyan K, Eighty Eka Pramyrtha Hestianah, Eka Pramyrtha Endang Setyaningsih endra, priawasana Erma Safitri Erry Gumilar Dachlan, Erry Gumilar Gandul Atik Yuliani Hana Eliyani Hani Plumeriastuti Hariadi, Mas'ud Hermanto Hermanto Hermanto Tri Joewono Hidajati, Nove Hidayatullah, Amiruddin IMAM MUSTOFA INDRA YULIATI, INDRA Iwan Sahrial Hamid Jeanita, Winny Jojor Sihotang Kartikasari, Dhesy Khasanah, Rima Nur Kuncorojakti, Suryo Kurniawati, Sepvian Dewi Lilik Maslachah Luqman, Epy Muhammad Machmudia, Ainun Mafruchati, Maslichah Meles, Dewa Ketut Muninggar, Laili Ngakan Made Rai Widjaja Ningrum, Nyna Puspa Nurbayatin, Anita Nursadida, Milla Nusdianto Triakoso Pardede, Sabrina Melisa Pardede, Sabrina Melisa Paulus Sugianto, Paulus Permatasari, Dian Ayu Poedjo Hartono Poetranto, Emmanuel Djoko Portia Sumarsono, Portia Pudji Srianto Rahadyan, Raihan Alif Rahayu, Pipit Sri Estuning Rahmaniabdi, El Roy Achmad Rao, Sherbrina Bai Seenivasa Relly Yanuari Primariawan, Relly Yanuari Rimayanti Rimayanti RINA YUDIWATI BM, RINA Risna Y, Dyah Ayu Roro Rochmah Kurnijasanti Rusyawardani, Aldis Ingrid Sami, Abdul Sarudji, Suryanie Shabira, Zahra Sri Mulyati Sri Pantja Madyawati, Sri Pantja Suherni Susilowati Sulistiawati Sulistiawati Suzanita Utama Tias, Eriza Putri Ayu Ning Tita Damayanti Lestari Tjuk Imam Restiadi Tri Wahyu Suprayogi Tyasningsih, Wiwiek Viski Fitri Hendrawan Wahyuni, Retno Sri Wicaksono, M Galih Widya Paramita Lokapirnasari Wiranata, Try Ardhi Wurlina, W Yaner, Nurul Ramadhani Yeni Dhamayanti Yudhana, Aditya Yulianna Puspitasari