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All Journal Jurnal Kedokteran Diponegoro PENELITIAN DAN KARYA ILMIAH Universa Medicina Jurnal Kreativitas PKM Acta Biochimica Indonesiana Jurnal Biomedika dan Kesehatan JURNAL PENELITIAN DAN KARYA ILMIAH LEMBAGA PENELITIAN UNIVERSITAS TRISAKTI Jurnal Penelitian dan Karya Ilmiah Lembaga Penelitian Universitas Trisakti JUARA: JURNAL WAHANA ABDIMAS SEJAHTERA JURNAL ABDI MASYARAKAT INDONESIA (JAMIN) Jurnal Abdimas Kesehatan Terpadu Jurnal Pengabdian Masyarakat Trimedika
Husnun Amalia
Departement Of Opthalmology, Faculty Of Medicine, Universitas Trisakti, Jakarta, Indonesia
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Lensa kontak: keamanan dan pencegahan komplikasi Husnun Amalia
Jurnal Biomedika dan Kesehatan Vol 1 No 3 (2018)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2018.v1.170-171

Abstract

Lensa kontak saat ini dikenal oleh masyarakat secara luas dan sering digunakan dalam kehidupan sehari-hari.(1) Lensa kontak adalah alat bantu yang diletakkan di permukaan kornea, mudah digunakan, nyaman untuk beraktivitas dan berolahraga. Fungsi utamanya adalah untuk mengatasi gangguan refraksi dengan keunggulan memberikan lapang pandang lebih luas dan lebih baik secara estetik.(2)Saat ini penggunaannya telah berkembang menjadi atribut mode dan estetika.(3) Indikasi penggunaan lensa kontak lainnya adalah terapeutik (ulkus kornea, erosi kornea, albino, aniridia, post operasi kornea), preventif simblefaron, diagnostik dan occupational (olahragawam, pilot, aktor).(2)Lensa kontak yang sering digunakan adalah lensa kontak lunak (softlens) yang berbahan hidrogel atau silicon hidrogel.(4)
Efek sinar biru pada kornea, lensa dan retina Husnun Amalia
Jurnal Biomedika dan Kesehatan Vol 2 No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2019.v2.1-2

Abstract

Penggunaan gawai yang mengandung sinar biru dengan durasi tertentu dapat menyebabkan kelelahan mata sehingga sebaiknya pengguna dapat lebih bijaksana dalam menggunakan gawai untuk mencegah terjadinya kelelahan pada mata.(7) Mencegah dan mengontrol kerusakan yang diakibatkan oleh sinar biru merupakan hal yang sangat penting. Hal yang dapat dilakukan adalah dengan menggunakan filter sinar biru pada media elektronik atau kacamata anti sinar biru, mengurangi penggunaan media elektronik pada malam hari dan mengkonsumsi antioksidan dengan cukup.
Review: penyakit virus corona baru 2019 (COVID-19) Nany Hairunisa; Husnun Amalia
Jurnal Biomedika dan Kesehatan Vol 3 No 2 (2020)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2020.v3.90-100

Abstract

Sebuah virus corona baru diidentifikasi sebagai SARS-CoV-2, pertama kali teridentifikasi di Wuhan, Cina, pada Desember 2019 dan dikenal dengan nama COVID-19. Memiliki 85% homologi dengan SARS-CoV, S-protein pada virus ini akan mengikat reseptor target (ACE2) pada manusia terutama pada paru, jantung, dan ginjal. COVID-19 memiliki masa inkubasi lebih lama dan penularannya lebih tinggi. Penularan terjadi melalui droplet saluran nafas dan kontak erat dengan penderita. Pandemi terjadi dengan sangat cepat, hingga 19 Mei 2020 telah teridentifikasi 4.943.077 kasus dengan angka kematian 321.998 orang dari 212 negara. Gejala yang paling sering muncul adalah demam, fatique, batuk kering, myalgia, dan sesak. Tingkat keparahan penyakit meningkat pada lansia dan penderita dengan komorbid (penyakit jantung, diabetes melitus, penyakit paru kronis, hipertensi, dan kanker). Infeksi ini memiliki CFR sebesar 2.3% dan komplikasi yang paling sering menyebabkan kematian adalah komplikasi pada jantung dan paru. Hingga saat ini belum ditemukan pengobatan yang tepat maupun vaksin untuk penyakit ini, namun penelitian guna pengembangan pengobatan dan vaksin terus dilakukan di seluruh dunia. Upaya maksimal harus dilakukan karena wabah ini mempengaruhi infrastruktur kesehatan publik, ekonomi, dan seluruh aspek di semua negara di dunia. Tindakan pencegahan adalah sangat penting sebagai upaya memutus mata rantai penularan COVID-19.
Ketepatan hasil pengukuran keratometri dengan ukuran astigmatisme pada ametropia Handriwei Handriwei; Husnun Amalia
Jurnal Biomedika dan Kesehatan Vol 3 No 3 (2020)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2020.v3.131-136

Abstract

LATAR BELAKANGEmetropia adalah kondisi mata yang tidak memiliki kelainan refraksi atau mata normal. Sinar sejajar yang datang dari jarak tak berhingga akan difokuskan tepat di retina (makula). Sedangkan kondisi mata yang memiliki kelainan refraksi dikenal dengan ametropia, yaitu sinar sejajar yang datang dari jarak tak berhingga tidak dapat difokuskan tepat di makula. Ametropia terdiri dari miopia, hipermetropia dan astigmatisme. Astigmastisme adalah keadaan di mana sinar-sinar sejajar tidak dibiaskan pada satu titik fokus. Pengukuran astigmatisme dilakukan dengan obyektif dan subyektif. Secara obyektif dilakukan pengukuran keratometri dengan alat keratometer. Pengukuran secara subjektif dilakukan dengan pemeriksaan refraksi. Kedua hasil pengukuran tersebut dapat berbeda sehingga dapat berpengaruh pada tatalaksananya. Pengukuran astigmatisme kornea yang tepat sangat penting pada tatalaksanan astigmatisme. Oleh karena itu, peneliti tertarik untuk melakukan penelitian ini untuk mengetahui ketepatan hasil pengukuran keratometri dengan ukuran astigmatisme pada ametropia. METODEPenelitian ini menggunakan desain analitik observasional dengan desain potong lintang. Penelitian dilakukan di Rumah Sakit Masmitra, Bekasi pada bulan Februari-April 2019 dengan sampel 186 mata. Data keratometri dan astigmatisme didapatkan dari rekam medis yang dilakukan oleh dokter spesialis mata. Analisis data menggunakan uji Chi-square dengan tingkat kemaknaan sebesar 0.05. HASILAnalisis Chi-square menunjukkan astigmatisme lebih banyak ditemukan pada usia lansia (p=0.785). Tidak terdapat hubungan yang bermakna antara ketepatan hasil pengukuran keratometeri dengan astigmatisme pada berbagai kelompok usia (p=0.062). KESIMPULANTidak terdapat hubungan antara ketepatan hasil keratometri dan astigmatisme pada ametropia.
Omicron penyebab COVID-19 sebagai variant of concern Husnun Amalia
Jurnal Biomedika dan Kesehatan Vol 4 No 4 (2021)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2021.v4.139-141

Abstract

Virus penyebab COVID-19, SARS-CoV-2 terus mengalami mutasi membentuk varian baru. Varian terbaru yang telah terdeteksi, yaitu varian Omicron yang dikenal sebagai varian B.1.1.529.(1) Varian ini pertama kali dilaporkan di Afrika Selatan pada tanggal 24 November 2021 dan saat ini telah menyebar ke seluruh dunia.(1,2)
Review: Pengaruh Nanopartikel ZnO sebagai Antimikroba pada Multidrug Resistance Klebsiella Pneumonia Nuha Kudaer; Mohsen Hashim Risan; Emad Yousif; Mohammed Kadhom; Rasha Raheem; Nany Hairunisa; Husnun Amalia
Jurnal Biomedika dan Kesehatan Vol 5 No 3 (2022)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2022.v5.236-242

Abstract

Klebsiella pneumoniae (K. pneumoniae)is a common microorganism for different infections, including respiratory, urinary tract, and biliary diseases, where immunocompromised individuals are directly affected by this bacterium. However, with the emergence of hypervirulent strains, individuals,whether healthy or immunocompetent, are equally susceptible to K. pneumoniae infections. This problem is diagnosed by the wide spreading of multidrug-resistant bacteria in the environment with multiple resistance mechanisms, which are the main challenges for an effective treatment. This put physicians in an inflexible confusion because of the limitation of medical treatment options. Among many remedy substances, zinc oxide (ZnO) nanoparticles (NPs) showed remarkable antibacterial properties versus many Gram-positive and Gram-negative bacteria. This work focuses on presenting the influence of these NPs on the expression of genes in charged in generating the K. pneumoniae capsule. Furthermore, perspectives for applying ZnO NPs in clinical practices are also discussed. As the in vivo studies show a powerful impact of ZnO on bacteria, it is anticipated that this method of treatment will be utilized by hospitals.
DETEKSI DAN PENYULUHAN PENYAKIT AKIBAT KERJA PADA PENGUPAS KERANG HIJAU DI CILINCING, JAKARTA UTARA Amalia, Husnun; Hairunisa, Nany; Mashabi, Yasmine; Zaina, Nashita Amira
Jurnal Abdi Masyarakat Indonesia (JAMIN) Vol 6 No 2 (2024): JURNAL ABDI MASYARAKAT INDONESIA (JAMIN)
Publisher : Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jamin.v6i2.17861

Abstract

DKI Jakarta is the most populous city in Indonesia and 59.29% of North Jakarta's population are fishermen, and Cilincing is the largest producer of green mussels in DKI Jakarta with 286 green mussel fishermen (2010), which is 70% of the total number of green mussel fishermen of DKI Jakarta and involves around 1,200 workers. The professions of the community are fishermen and clam collectors (25%), shellfish peel workers (8%), and shellfish traders (6%). The profession of shelling shells is carried out less ergonomically for 6-8 hours a day. This can lead to occupational diseases including Low Back Pain, Frozen shoulder, trigger finger, and the threat of chemical hazards. This service activity aims to detect occupational diseases in green mussel peeling workers and provide preventive information so that the disease does not occur. The consultation and examination activities were attended by 87 residents, aged from 5-84 years. Occupational diseases are mainly found in residents who are still actively working in the Green mussel peeling industry. Occupational diseases are found to be fit for duty in this industry. The lifting officer seemed to lift less ergonomic activities so that abnormalities of Hernia Nucleus Purposus (HNP), myalgia Shoulder pain, and Low Back Pain (LBP) were detected. Scallop peelers complain of low back pain (LBP), neck pain, and Carpal Tunnel Syndrome (CTS). Counseling participants are women working as green mussel peelers aged 20-73. The duration of working hours per day > 5 hours (92.3%). Education level is low (76.9%) and length of work experience varies between 1->30 years. Counseling showed good results, judging from the post-test scores 100% of participants showed good results. Workers need follow-up from various parties to prevent occupational diseases in green mussel peeling workers.
Survei Pola Kuantitas Peresepan Antibiotik di Tiga Rumah Sakit di Indonesia dengan Penatagunaan Antimikroba Digital Natadidjaja, Ronald Irwanto; Lekok, Widyawati; Ariyani, Aziza; Adlani, Hadianti; Adianto, Raymond; Maharani, Ronaningtyas; Sumarsono, Hadi; Yenny, Yenny; Samira, Jihan; Hairunisa, Nany; Amalia, Husnun; Faradila, Meutia Atika; Fadilah, Tubagus Ferdi; Kalumpiu, Joice Viladelvia; Yuliana, Yuliana; Mulyani, Sri; Anggiat, Desi; Marja, Triyoko Septio; Pertiwi, Iin Indra; Dianawati, Dianawati; Legoh, Grace Nerry; Rantung, Alvin Lekonardo
Jurnal Biomedika dan Kesehatan Vol 8 No 2 (2025)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background Antimicrobial Stewardship Program (ASP) is very essential. There are three categories of antimicrobial agents as recommended by WHO: Access, Watch and Reserve. e-RASPRO, a digital ASP model, may alter antibiotic prescribing patterns by prioritizing Access category antibiotic prescribing. Methods Our manuscript presented a quantitative survey on antibiotic prescribing patterns within 3 months and 9 months before and after implementing digital electronic-RASPRO (e-RASPRO) in three Indonesian hospitals, utilizing retrospective inpatient data. This analysis included the appropriateness of empirical antibiotic prescribing and the quantity of antibiotic prescribing based on each category. Results In the first 3 months, we found that 90.16%, 83.98%, and 81.15% of patients were included in Type 1 Risk Stratification. The appropriateness of initial empirical antibiotic prescribing with the digital guideline on antimicrobial use of e-RASPRO in three hospitals was 81.59%, 76.09% and 24.48%, respectively. Within 9 months after implementing e-RASPRO in Hospital A and B and within 3 months in Hospital C, there was a trend of reduced quantity of Watch category antibiotic prescribing of 54.93% (-58.86% per inpatient), 21.11% (-9.97% per inpatient), and 8.59% (-4.15% per inpatient), respectively. There was a 12.42% (+2.61 % per inpatient) and 223.17% (+268.83% per inpatient) increase in the quantity of Access category antibiotic prescribing in Hospitals A and B, while in Hospital C, the quantity decreased by 6.81% (-2.29% per inpatient).   Conclusions There are changes in antibiotic prescribing patterns, particularly in the antibiotics included in the Watch and Access categories following the implementation of e-RASPRO. The relationship between digital antimicrobial stewardship use and the results still needs further research.
Deteksi gen secara Epidemiologi Molekuler pada Isolat Klinik Klebsiella pneumoniae dari Pasien Dewasa dengan komorbid di Rumah Sakit Baghdad Kudaer, Nuha B; Risan, Mohsen Hashim; Raheem, Rasha; Zainulabdeen, Khalid; Salman, Israa; Hairunisa, Nany; Amalia, Husnun; Hameed, Seenar; Yousif, Emad
Jurnal Biomedika dan Kesehatan Vol 6 No 2 (2023)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2023.v6.196-215

Abstract

Background Klebsiella species is one of the most worldwide opportunistic pathogens in the world that cause infections at multiple sites like lung, urinary tract, bloodstream, wound or surgical site, and brain. Klebsiella pneumoniae has many types of virulence factors that give the bacteria the ability to invade the host and cause infections. Methods A total of (105) human clinical samples were collected from different patients with different cases. Klebsiella pneumonia were isolated from 30 samples. The bacteria were identified by biochemical tests and certified by using VITEK 2 system and genetically by amplify using PCR for 16 rRNA gene. One of the Klebsiella pneumoniae virulence factors is the capsule that is responsible for the macrophage resistance and its also responsible for serotype. So to confirm the strains isolated, PCR Gene detection of, MagA, K2A, RmpA, and Kfu, where (magA, k2A, rmpA, kfu) gens are responsible for capsule synthesis of Klebsiella pneumonia have been done. Results There were 30 strains of Klebsiella pneumoniae were identified. Epidemiological studies show that infections are preceded by gastrointestinal colonization, with the gastrointestinal tract being the most important reservoir for transmission. The primary bacterial isolates were identified based on their cultural, microscopic, and biochemical traits. The API system (API 20E) and VITEK 2 systems were used to confirm the identity of the bacterial isolates. Colony morphology revealed that Klebsiella pneumonia was Gram-negative, non-motile, microscopic straight rods grouped singly or in pairs. Biochemical tests showed that neutral end products prevailed over acidic end products, with Klebsiella producing negative results for indole. The Kligler Iron Agar (KIA) test showed that Klebsiella isolates changed the color of the slant and butt, producing an acidic slant and acid butt, along with gas production. The urease test for Klebsiella distinguishes between Enterobacter and Klebsiella isolates, as Klebsiella can manufacture the urease enzyme. The indole test distinguishes K. pneumonia from K. pneumonia from K. mobiliz. The API 20E system was used for biochemical testing, and the VITEK 2 system was used for identification. The VITEK 2 system was used to test for biochemical and antibiotic susceptibility, and the results supported the findings from morphological and biochemical analyses. PCR amplification was used for molecular detection, and all nine isolates tested positive for the magA and k2A genes. The ferric iron uptake system gene (kfu) and the extracapsular polysaccharide synthesis regulator gene (rmpA) were amplified using specific primer pairs. The VITEK 2 system demonstrated promising outcomes for K. pneumoniae identification. However, standard diagnostic methods are costly and time-consuming. Conclusions Navigating the complex landscape of infectious diseases, collaborative research projects have become indispensable in unraveling the mysteries surrounding pathogens. The project in Baghdad, having stood as a shining example of such collaboration, provided valuable insights into the identification, characterization, and molecular aspects of Klebsiella pneumoniae strains. The findings, have not only contributed to the scientific community's understanding of bacterial infections but also paved the way for enhanced strategies in diagnosis and treatment.
Studi Faktor-Faktor yang Berhubungan dengan HIV pada Perempuan di Kalimantan Barat, Indonesia Hairunisa, Nany; Sabrina, Isra; Amalia, Husnun; Mashabi, Yasmine; Zaina, Nashita Amira; Yousif, Emad
Jurnal Biomedika dan Kesehatan Vol 6 No 1 (2023)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2023.v6.89-107

Abstract

Background According to national data, West Kalimantan is one of the ten top provinces that reported AIDS cases, ranked eighth. Until December 2019, based on data recorded in the Provincial Health Office that reported to the Indonesia Ministry of Health, the AIDS case rate in West Kalimantan was 49.35, showing over the national AIDS case rate (38.93). In this study, an unmatched case-control determines the factors associated with HIV/AIDS among women in West Kalimantan, Indonesia. Methods The study was conducted among 90 women who tested positive for HIV/AIDS (cases) and 90 who tested negative for HIV/AIDS (controls). Data were collected using questionnaires from June 2019 to August 2019 at three community health centres in West Kalimantan. Data were analyzed using IBM Statistical Package Social Science (SPSS) 19. Descriptive analyses and Multivariate logistic regression analysis were used to examine the factors associated with HIV/AIDS. Results: This study has found a significant association between crucial aspects such as marital status, occupation, knowledge about HIV/AIDS, HIV treatment, and VCT (Voluntary Counseling and Testing) service program with cases of HIV/AIDS. A significant association between marital statuses with HIV/AIDS suggests that divorced/widowed have a higher risk of having HIV/AIDS, followed by the married group. Women with good educational backgrounds will likely know how to prevent HIV infection and take preventive measures to protect themselves. Results This study found a significant relationship between several important aspects such as marital status, occupation, knowledge of HIV/AIDS, HIV treatment, and the VCT (Voluntary Counseling and Testing) service program with HIV/AIDS cases. The significant relationship between marital status and HIV/AIDS shows that divorced/widows have a higher risk of contracting HIV/AIDS, followed by the married group. Women with a good educational background tend to know about HIV infection prevention measures and take precautions to protect themselves. Conclusions Some factors are significantly related to HIV/AIDS. Thus, educating women about sex could potentially decrease the number of HIV/AIDS cases.
Co-Authors Adhiwardan, Anggraeni Adianto, Raymond Adlani, Hadianti Ahmed, Dina Alsayed, Raghda Alvina Alvina Andrianjah Andrianjah, Andrianjah Anggiat, Desi Anggraeni Adiwardhani Antin Tri Laksmi Ari Estuningtyas, Ari Ariyani, Aziza Bella, Isa Christian Christian David Tjahyadi dianawati, dianawati Diani Nazma Diani Nazma Djebli, Noureddine Effendi, Ida Emad Yousif Erlani Kartadinata Erlani Kartadinata, Erlani Eveline Margo, Eveline Faradila, Meutia Atika Ferdhian, Farrel Ferina, Mutiara Grace Nerry Legoh Gusti G. Suardana, Gusti G. Hadi Sumarsono Hairunisa, Nany Hameed, Seenar Handriwei Handriwei HANS-JOACHIM FREISLEBEN Hosea Jaya Edy Husain, Amani Irawan, Achmad Isa Bella Johan Hutauruk Joice Viladelvia Kalumpiu, Joice Viladelvia Kadhom, Mohammed Karina Karina Karlina Mahardieni Kartini Kartini Kudaer, Nuha B Kurniasari LEKOK, WIDYAWATI Lira Panduwaty Lira Panduwaty Maharani, Ronaningtyas Mahdi, Sarah Marja, Triyoko Septio Mashab, Yasmine Mashabi, Yasmine Mohammed Kadhom Mohsen Hashim Risan Monica Dwi Hartanti Monica Dwi Hartanti, Monica Dwi Mun’im, Abdul Mustopa, Ita Tazkiatul Izzati Nadia Fernanda Natadidjaja, Ronald Irwanto Noviani Prasetyaningsih Noviani Prasetyaningsih Nuha Kudaer Oladimeji, Ashaolu Victoria Onny Hernik Saputro Parwanto, Edy Patricia Budihartanti Liman Pertiwi, Iin Indra Prasetyaningsih, Noviani Pratiwi, Luh Ade Dinda Pradnya Pratiwi, Megawati Yulia Wina Rachmiyani, Irmiya Raheem, Rasha Rahman, Athaya Nayla Pasca Rahmawati Ridwan Rantung, Alvin Lekonardo Rasha Raheem Ratna Sitompul Redwan, Amamer M Risan, Mohsen Hashim Robiatul Adawiyah Sabrina, Isra Salman, Israa Samira, Jihan Sri Mulyani Thamer, Hamsa Trilaksmi, Antin Tubagus Ferdi Fadilah, Tubagus Ferdi Widya Artini Witjaksana, Riani YENNY YENNY Yohana Yousif, Emad Yuliana Yuliana Yuliarsa, Cyntha Nasyanda Yusop, Rahimi M Zaina, Nashita Amira Zainulabdeen, Khalid Zalfa, Afifah