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All Journal Buletin Farmatera Journal of Epidemiology and Public Health Indonesian Journal of Medicine Contagion: Scientific Periodical Journal of Public Health and Coastal Health Best Journal (Biology Education, Sains and Technology) Jurnal Prima Medika Sains Jurnal Pengabdian pada Masyarakat Kepulauan Lahan Kering Multidiciplinary Output Research for Actual and International Issue (Morfai Journal) Jurnal Pengabdian Pada Masyarakat METHABDI Majalah Ilmiah METHODA Cermin Dunia Kedokteran
Siahaan, Jekson Martiar
Institut Kesehatan Deli Husada Deli Tua
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PENYULUHAN KONTROL HIPERTENSI DAN DIABETES SEJAK DINI KEPADA JEMAAT GEREJA HKBP GEDUNG JOHOR RESORT, KECAMATAN MEDAN JOHOR Anto, Endy Juli; Hutasoit, Eka Samuel P.; Siahaan, Jekson M.; Rimbun, Surjadi; Manullang, Frengky S.; Tiji, Widjaya Taufik; Tambunan, Ronald Tunggul Hotmarojahan; Lim, Hadyanto; Pasaribu, Sumihar Maurist Rantos; Tarigan, Menang Bastanta; Jamnasi, Juli; Sinatra, Jadeny; Silitonga, Hendrika Adriana
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 3 No 2 (2023): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methabdi.Vol3No2.pp128-132

Abstract

Community Service (PKM) in the form of health education conducted by lecturers at the Faculty of Medicine, Indonesian Methodist University provides outreach about the benefits of controlling hypertension and diabetes mellitus from an early age. PKM was held on August 5 2023 at the HKBP church, Medan Johor District, North Sumatra. Lectures, question and answer discussions and motivation are used as orientation methods. A question and answer discussion was held with the aim of gaining insight and understanding to avoid complications from hypertension and DM. The results of PKM's socialization and work are very effective considering that there are still many people who have not received information about the benefits of vaccination through the basic immunization program. This education makes people more aware of the importance of routine control of health services. The HKBP church community must be aware and know the importance of early control in avoiding complications.
Penyuluhan Otitis Media Akut kepada Anak Panti Asuhan Advent Peduli Sembiring, Budi Darmanta; Anto, Endy Juli; Fauzi, Tengku Muhammad; Siahaan, Jekson Martiar; Tarigan, Menang Bastanta; Sijabat, Kesia; Sihaloho, Kerin Repaskatri; Manik, Widya Dayanti Feronika; Simanjuntak, Jeremia; Wijaya, Mega; Sihaloho, Lovian Nauli; Sembiring, Mikael; Panjaitan, Bintang Andika; Sitompul, Michael Sabatino; Momot, Estela Salomina
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 4 No 1 (2024): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methabdi.Vol4No1.pp6-10

Abstract

In accordance with the application of the Tri Darma of Higher Education in the doctor's professional study program, one of which is community service. The purpose of community service activities is to provide explanations and education that can influence community behavior. This community service was carried out at an advent orphanage caring for children and adolescents with 25 participants. This community service activity was carried out on December 6, 2023, with the material of acute otitis media. This topic is very much needed in order to provide information and knowledge about acute Otitis media. Behavior to maintain ear hygiene and health to prevent this disease. Lack of knowledge many are subjected to unfavorable issues. Through this health counseling, it is expected that children and adolescents at Advent Peduli Orphanage, Gg. Kasih no 8, Sudirejo II, Kec. Medan Kota are always motivated to stay alert when playing with friends and keep their ears healthy.
CHAYOTE (SECHIUM EDULE JACQ. SWARTZ) EXTRACT AND FRACTIONS IMPROVE MDA LEVELS AND TESTOSTERONE HORMONES IN MALE RATS WITH TYPE 2 DIABETES Imelda Montes Monika Simanungkalit; Jekson Martiar Siahaan; Hendrika Silitonga
Multidiciplinary Output Research For Actual and International Issue (MORFAI) Vol. 4 No. 4 (2024): Multidiciplinary Output Research For Actual and International Issue
Publisher : RADJA PUBLIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/morfai.v4i4.2414

Abstract

This study aimed to analyze the effects of chayote (Sechium edule Jacq. Swartz) extract and fractions on male reproductive function, specifically by observing Malondialdehyde (MDA) levels and testosterone hormones, in a rat model of type 2 diabetes. The study used a laboratory experimental method with a posttest-only controlled group design on male Wistar rats. The rats were randomized into 17 groups, including a negative control group, a positive control group, and groups that received ethanol extract, n-hexane fraction, ethyl acetate, and water of chayote at doses of 50 mg/KgBW, 100 mg/KgBW, and 150 mg/KgBW. The results showed that the ethanol extract, n-hexane fraction, and ethyl acetate of chayote can reduce MDA activity and increase testosterone hormone levels in male white rats (Rattus novergicus) induced by streptozotocin, NA, and HFD. This study suggests that chayote has the potential to be used as a natural ingredient to improve male reproductive function in people with type 2 diabetes.
Literature Review: Relationship Between Rubber Factory Pollution Exposure and Reactive Oxygen Species (ROS) Levels in Workers Pasaribu, Sumihar MR; Purba, Amril; Perangin-angin, Guntur; Siahaan, Jekson Martiar
Buletin Farmatera Vol 10, No 3 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i3.25610

Abstract

Abstract: Working in rubber factories exposes personnel to a cocktail of airborne contaminants—hydrogen sulfide, organic solvents, and fine dust—that jeopardise health over the long term. A key pathological response to such pollution is the upsurge in reactive oxygen species (ROS), which drives oxidative stress and underlies injury to cells, tissues, and organ systems. The present review compiles biomarker and mechanistic data showing how encounters with factory fumes correlate with elevated ROS levels in exposed workers. Cross-sectional surveys and laboratory experiments consistently report raised indicators such as malondialdehyde (MDA) and 8-hydroxy-2-deoxyguanosine (8-OHdG), establishing a robust link between airborne toxins and molecular damage. Genetic variants that weaken antioxidant enzymes further shape individual risk, reminding us that not every worker faces the same burden even under identical exposure conditions. Consequences typically affect the respiratory tract, heart, and metabolic pathways, reinforcing calls for stronger engineering controls, personal monitoring, and health surveillance in the plant. Early trials of antioxidant supplements show promise for damping ROS pathways, yet the field still lacks evidence-based protocols that tailor interventions to sources and dosages of pollution. By clarifying these oxidative processes, the review aims to guide regulators and industry managers in crafting rules that truly protect workers' lives and livelihoods
Antidiabetic and Anti-inflammatory Effects of Peperomia pellucida Leaf Extract: Modulation of Blood Glucose, IL-1β, and Pancreatic Histopathology in STZ-Induced Diabetic Rats Oktavia, Ria; Anto, Endy Juli; Siahaan, Jekson Martiar
Indonesian Journal of Medicine Vol. 10 No. 3 (2025)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2025.10.3.870

Abstract

Background: Diabetes mellitus (DM) is a significant global health challenge with a rapidly increasing prevalence. Although synthetic antidiabetic drugs remain the standard treatment, long-term use often leads to adverse side effects, prompting exploration of natural alternatives. This study investigated the therapeutic potential of ethanol extract of Peperomia pellucida (L.) Kunth leaves in diabetes management through comprehensive assessment of glycemic control, inflammatory marker (IL-1β), and pancreatic tissue histopathology. Subjects and Method: Thirty male Wistar rats were randomized into five groups (n=6): normal control, negative control (STZ-induced), positive control (STZ+metformin 50 mg/kg BW), and two treatment groups receiving Peperomia pellucida extract at doses of 40 mg/kg BW and 80 mg/kg BW, respectively. After 7 days of treatment, blood glucose levels, serum IL-1β concentrations, and pancreatic histopathology were evaluated. Phytochemical screening was conducted to identify bioactive compounds in the extract. Results: Phytochemical analysis confirmed the presence of alkaloids, flavonoids, tannins, saponins, and phenolics. Blood glucose measurements showed significant intergroup differences on day 0 (p<0.001) and day 7 (p<0.001). The 80 mg/kg BW extract group showed a reduction in blood glucose from day 0 (Mean=312.83; SD=40.92) to day 7 (Mean=281.00; SD=34.86). IL-1β serum analysis revealed significant differences among groups (p<0.001), with lower IL-1β levels observed in extract-treated groups compared to the negative control. Histopathological examination demonstrated improved pancreatic tissue structure in extract-treated groups, especially at higher doses. Conclusion: Ethanol extract of Peperomia pellucida (L.) Kunth leaves exhibits promising antidiabetic and anti-inflammatory properties in STZ-induced diabetic rats, as evidenced by reduced blood glucose, decreased IL-1β levels, and improved pancreatic histology. These findings suggest that Peperomia pellucida (L.) Kunth is a potential candidate for the development of natural therapies for diabetes management.  
POTENSI LABU SIAM SEBAGAI ANALGETIK Sinatra, Jadeny; Siahaan, Jekson M.
Majalah Ilmiah METHODA Vol. 14 No. 1 (2024): Majalah Ilmiah METHODA
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methoda.Vol14No1.pp8-16

Abstract

Pain is an unpleasant emotional sensation. Pain can begin after inflammation and/or after tissue damage. The use of analgesic or anti-pain drugs so far has undesirable side effects, so people have begun to look for alternative traditional medicines as a substitute. One of the plants that can be used as an alternative medicine for analgesics is chayote (S. edule). The purpose of this review is to provide information about chayote as an analgesic. This study focused on reviewing articles on experimental studies conducted in vivo and its bioactive components.
Sensitivitas Dan Spesifitas Pemeriksaan Mikroskopis Sputum BTA Terhadap Tes Cepat Molekuler (TCM) Dalam Diagnosis Mycobacterium Tuberculosis Pada Pasien Suspek Tuberkulosis Paru Di Puskesmas Sigambal Siahaan, Jekson Martiar; Sari, Nur Mala; Fahdi, Firdaus; Panjaitan, Goklas
BEST Journal (Biology Education, Sains and Technology) Vol 8, No 1 (2025): Juni 2025
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v8i1.11963

Abstract

Tuberculosis merupakan penyakit infeksi paru yang disebabkan oleh infeksi Mycobacterium tuberculosis. Pemeriksaan mikroskopis BTA merupakan pemeriksaan untuk menemukan adanya basil tahan asam dalam sputum dan pemeriksaan TCM dapat mendeteksi adanya kuman Mycobacterium tuberculosis dengan pemeriksaan molekuler dan juga mendeteksi resistensi M. tuberculosis terhadap rifampisin. Penelitian ini bertujuan untuk mengetahui sensitivitas dan spesifisitas hasil pemeriksaan mikroskopis sputum BTA terhadap tes cepat molekuler (TCM) pada suspek TB Paru. Metode penelitian ini adalah survey deskriptif analitik dengan rancangan penelitian cross sectional, dilaksanakan di RSUD Bangkinang, penelitian dilakukan selama 6 bulan pada tahun 2023. Sampel yg digunakan dalam penelitian ini adalah seluruh populasi yang merupakan suspek TB Paru di RSUD Bangkinang. Dari hasil penelitian terhadap 100 sampel, didapatkan hasil positif pada pemeriksaan TCM sebanyak 15, hasil negatif pada pemeriksaan TCM sebanyak 85. Sedangkan pada pemeriksaan mikroskopis BTA diperoleh hasil positif sebanyak 88 dan hasil negatif pada pemeriksaan mikroskopis BTA sebanyak 12. Dari uji diagnostik didapat kan nilai sensitivitas 80% dan nilai spesifisitas 100% pada pemeriksaan mikroskopis BTA terhadap TCM
Systemic Barriers to Postpartum Midwifery Visits and Their Effect on Exclusive Breastfeeding in Rural Indonesia Ariani, Peny; Ariescha, Putri Ayu Yessy; Bahar, Dinillah Salsabila; Siahaan, Jekson Martiar; Sari, Nurmala
Contagion: Scientific Periodical Journal of Public Health and Coastal Health Vol 7, No 2 (2025): CONTAGION
Publisher : Universitas Islam Negeri Sumatera Utara, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/contagion.v7i2.24285

Abstract

Postpartum visits by independent midwives play a critical role in initiating and sustaining exclusive breastfeeding. However, operational and institutional barriers may compromise their effectiveness, particularly in semi‑urban and rural settings such as Deli Tua District. This study examined the association between these barriers and exclusive breastfeeding practices among mothers in Deli Tua. A quantitative cross-sectional study was conducted in 2025, involving all independent midwives in the district (n = 85) and a purposive sample of 120 postpartum mothers (1–6 weeks post-delivery). Data were collected using structured questionnaires and analyzed through Chi-Square tests and multivariate logistic regression at a 95% confidence level. Key barriers negatively associated with exclusive breastfeeding included lack of government incentives (OR = 0.23; 95% CI: 0.09–0.61; p = 0.004), excessive workload and fatigue (OR = 0.33; 95% CI: 0.14–0.78; p = 0.013), high operational costs (OR = 0.38; 95% CI: 0.17–0.83; p = 0.015), and limited time for visits (OR = 0.43; 95% CI: 0.19–0.96; p = 0.043). Conversely, institutional support from health centers significantly increased the likelihood of breastfeeding success (OR = 2.01; 95% CI: 1.01–4.01; p = 0.046). Socio-cultural factors such as stigma and customary practices showed no significant association. To enhance the effectiveness of postpartum care and promote exclusive breastfeeding, the study recommends implementing performance-based incentives, reducing workload burdens, providing financial subsidies, and establishing standardized visit-time guidelines. Strengthening cross-sectoral collaboration and resource allocation is essential to improve service delivery and breastfeeding outcomes. Keywords: Exclusive breastfeeding, postpartum care, health system barriers, community midwives, maternal health services
Anti-inflammatory and Anti-infertility Effects of Ethanol Extract of Turmeric (Curcuma longa) in Male Wistar Rats with Type 2 Diabetes Mellitus Induced by Streptozotocin-Nicotinamide-High Fat Diet Vivian, Vivian; Lim, Hadyanto; Siahaan, Jekson Martiar; Anto, Endy Juli; Ilyas, Syaffrudin; Ardinata, Dedi
Indonesian Journal of Medicine Vol. 10 No. 4 (2025)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2025.10.4.891

Abstract

Background: Type 2 diabetes mellitus (T2DM) is a complex metabolic disorder associated with chronic inflammation and male reproductive dysfunction. The ethanol extract of turmeric (Curcuma longa) has demonstrated potential as an alternative therapeutic agent due to its anti-inflammatory and reproductive restorative properties. This study aims to analyze the anti-inflammatory and anti-infertility effects of the ethanol extract of Curcuma longa in male Wistar rats with T2DM induced by a streptozotocin-nicotinamide-high fat diet (STZ-NA-HFD). Subjects and Method: Thirty male Wistar rats were randomized into six groups (n=5): normal control (K1), diabetic control (K2), positive control (T2DM + metformin 45 mg/kgBW, K3), and three treatment groups receiving Curcuma longa extract at doses of 50 mg/kgBW (K4), 100 mg/kgBW (K5), and 150 mg/kgBW (K6). Diabetes was induced with STZ (55 mg/kgBW) and nicotinamide (120 mg/kgBW). Blood glucose, IL-6, testosterone levels, sperm count, and sperm motility were evaluated after 21 days of treatment. Results: The turmeric extract significantly reduced blood glucose levels (p<0.001) and IL-6 concentrations from 574.06±68.99 to 214.06±78.71 ng/mL at a dose of 150 mg/kgBW (p<0.001). Normal sperm motility increased significantly at 150 mg/kgBW (20.0±2.55%) compared to the diabetic control (8.40±2.07%) (p=0.008). Conclusion: The ethanol extract of Curcuma longa demonstrated significant anti-inflammatory activity by reducing IL-6 levels and improving glycemic control. Its anti-infertility effect was reflected by enhanced sperm motility, particularly at the 150 mg/kgBW dose. These findings indicate that Curcuma longa possesses potential as an adjuvant therapy for the management of T2DM and its associated complications.
Co-Authors Agnes Imelda Manurung Ainun, Nur Azizah Ardinata, Dedi - Ariani, Peny Ariescha, Putri Ayu Yessy Atmawidjaja, Rachmat Bahar, Dinillah Salsabila Br. T. Tambun, Gita Sradha Budi Darmanta Sembiring Butar-Butar, Harry Chalil, M. Jalaluddin A. Daulay, Agus Husein Dina Riani Purba Dona Pasaribu Dwi Lunarta Doderina Siahaan Efbertias Sitorus Eka Samuel P. Hutasoit Endy Juli Anto Endy Juli Anto endyjulianto Fadinie, Wulan FAHDI, FIRDAUS Fauzi, Tengku M. Fauzi, Tengku Muhammad Hadyanto Lim Hadyanto Lim Hakim, Enggrek Pelita Hamdi, Tasrif Hendrika A. Silitonga Hendrika Silitonga Hutagalung, Mangatas Halomoan Parluhutan Hutagalung, Sanggam B. Hutagalung, Sanggam Bangun Hutapea, Kenal P. Hutasoit, Eka Samuel P. Ilyas, Syaffrudin Imelda Montes Monika Simanungkalit Irfan Hamdani, Irfan Irina, Sinta Jadeny Sinatra Jan Pieter Sihombing Jones Simatupang Juli Jamnasi Juli Jamnasi Juli Y. Mega kenvin rusli Laura Octavina Siagian Lesmana Syahrir Lesmana Syahrir, Lesmana Lubis, Andriamuri P. Maestro B. U. Simanjuntak Maludin Panjaitan Manik, Widya Dayanti Feronika Manullang, Frengky S. Maria, Lasma Menang Bastanta Tarigan Momot, Estela Salomina Nababan, Manaor Bismar Posman Nababan, Titus Imanuel Nainggolan, Ranatha NH Nainggolan, Serevina Napitupulu, Helen Debora Natalie S., Karen Nazma, Diani Nurmala Sari Pakpahan, Edwin Anto Panataria, Lince Romauli Panjaitan, Bintang Andika Panjaitan, Goklas Parhusip, Rudolf S. Pasaribu, Sumihar M. R. Pasaribu, Sumihar Maurist Rantos Pasaribu, Sumihar MR Paul Saut Marganda L Tobing Perangin-angin, Guntur Pratiwi, Ade Dwi Purba, Amril Putri C. Eyanoer Putri Chairani Eyanoer Putri Chairani Eyanoer, Putri Chairani Ria Oktavia Ricke Loesnihari Rimbun, Surjadi Ronald T. H. Tambunan Sagala, Daniela Salamon, Yuda Monang Salomo G. U. Simanjuntak Salomo Garda Utama Simanjuntak Sanggam B Hutagalung Sanggam B. Hutagalung SARAGIH, MEYLIN KRISTINA Sari, Nur Mala Sembiring, Bob Agustinus Sembiring, Budi Darmanta Sembiring, Mikael Siahaan, Dwi Lunarta D. S. Sihaloho, Kerin Repaskatri Sihaloho, Lovian Nauli Sihombing, Amordekhai Imvan Parlindungan Sihombing, Parsaoran Sihotang, Ruth Wydia Wati Sijabat, Kesia Silaen, Ester L. R. Silalahi, Veraci Silangit, Thomas Silitonga, Hendrika Adriana Silitonga, Hendrika Andriana Silitonga, Hendrika Andriani Simangunsong, Batara Simanjuntak, Jeremia Simanjuntak, Maestro Simanjuntak, Maestro Bina Utama Simanjuntak, Pantas Simanjuntak, Salomo Garda Utama Simanjuntak, Salomo Garda Utama Simatupang, Aditia Erick Cantona Simbolon, Boyke M. Sinatra, Jadeny Sinurat, Suryati Sirait, Kilian Sitepu, John Frans Siti Normi, Siti Sitompul, Michael Sabatino Sitorus, Ragnar Oktavianus Stephanie S., Kezia Surjani, Lylys Suryati Sinurat Syahputra, Fahmi Tambunan, Ronald T. H. Tambunan, Ronald Tunggul Hotmarojahan Tampubolon, Ruth Septianna Br. Tanjung, Qodri F. Tarigan, Juliyanti Tarigan, Leonardo Tarigan, Menang Bastanta Tengku M. Fauzi Tengku Muhammad Fauzi Tiji, Widjaya Taufik Tobing, Paul S. M. L. Urip Harahap Vivian Vivian Wijaya, Mega Yohanna Agustina Sinaga YUNAFRI, ANDRI Zainumi, Cut M.