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Manajemen Anestesia pada Carotid Endarterectomy: Pasien dengan Kinking Arteri Karotis Interna Riyadh Firdaus; Iwan Fuadi; Sri Rahardjo; A Himendra Wargahadibrata
Jurnal Neuroanestesi Indonesia Vol 4, No 2 (2015)
Publisher : https://snacc.org/wp-content/uploads/2019/fall/Intl-news3.html

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2819.945 KB) | DOI: 10.24244/jni.vol4i2.113

Abstract

Prosedur Carotid Endarterectomy (CEA) adalah prosedur penting untuk pencegahan stroke karena sumbatan arteri karotis. Seorang laki-laki 71 tahun akan dilakukan operasi CEA. Pasien mengeluh pusing berputar, riwayat hipertensi diakui sejak 10 tahun dengan tekanan darah tertinggi 170/100 mmHg, riwayat stroke diakui 1 tahun yang lalu dan 1,5 bulan lalu. Gejala sisa stroke saat ini kelemahan extremitas sebelah kiri. Pasien terdapat riwayat sakit jantung, irama tidak teratur, tidak disertai sesak nafas 1 tahun yang lalu dan saat itu diberikan amiodaron tablet. Operasi dilakukan dengan anestesi umum, menggunakan pipa endotrakeal no.8.0, ventilasi kendali. Obat yang dipergunakan adalah midazolam 1 mg iv, fentanyl 150 mcg iv, propofol 70 mg iv, rocuronium 40 mg iv. Rumatan dilanjutkan dengan sevofluran, fraksi oksigen 45% dan propofol bolus jika diperlukan. Monitoring tanda vital (tekanan darah, nadi, SaO2, elektrokardiografi) dan artery line. CEA dilakukan selama 3,5 jam, tidak ditemukan stenosis tetapi terdapat kinking. Selama operasi hemodinamik relatif stabil. Pascaoperasi pasien di rawat di ruang perawatan intensif. Berbagai pendekatan bedah telah dikemukakan untuk kinking arteri karotis interna. Pilihan pendekatan dipengaruhi oleh pemilihan pasien, penilaian praoperasi optimasi, dan manajemen perioperatif perawatan untuk pasien yang akan menjalani CEA. Anesthetic Management for Carotid Endarterectomy:Patient with Internal Carotid Artery KinkingCarotid endarterectomy (CEA) is an important procedure for stroke prevention due to obstruction of carotid artery. A 71 years old male was scheduled for CEA surgery. The patient complained of spinning headache. He had been suffered from hypertension since 10 years ago with highest blood pressure of 170/100 mmHg, and had a two times stroke 1 year and 1.5 months ago. Sequelae symptom of stroke is weakness on the left extremity. Patient also had a history of heart disease, irregular rhythm, without shortness of breath approximatelly1year ago, treated with amiodarone tablets. The CEA operation was performed under general anesthesia using endotrachenal tube 8.0, controlled ventilation, 1 mg midazolam, 150 mcg fentanyl, 70 mg propofol and 40 mg rocuronium, given intravenously. Maintenance of anesthesia was done using sevoflurane, oxygen fraction of 45% and propofol 10 mg given intermittently as needed. Noninvasive vital signs monitoring and invasive arterial blood pressure were recorded. Hemodynamics were stable during the 3.5 hours operation. We found no plaque but a kinking on the carotid artery. Postoperatively, patients was admitted to the intensive care unit. Various surgical approaches have been done and developed to manage the internal carotid artery kinking. Options approach is influenced by patient selection, preoperative assessment and optimization, and perioperative management and care for patients undergoing CEA
Stroke pada Usia Muda Andi Basuki Prima Birawa; Lisda Amalia
Cermin Dunia Kedokteran Vol 42, No 10 (2015): Neurologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v42i10.955

Abstract

Hampir 10% stroke terjadi pada usia relatif muda (kurang dari 45 tahun). Angka kejadian stroke pada usia di bawah 45 tahun diperkirakan 7 – 15 kasus/100.000 penduduk/tahun dan lebih jarang pada kelompok anak-anak, yaitu 1 – 8 kasus/100.000/tahun. Faktor risiko terjadinya stroke pada usia muda berbeda-beda, antara lain: (1) Migren, (2) Sickle-cell disease, (3) Penyakit jantung, (4) Abnormalitas pembuluh darah serebral, (5) Focal cerebral arteriopathy of childhood (FCA), (6) Ensefalopati pasca-varisela, (7) Mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS), (8) Diseksi arteri, (9) Penyalahgunaan obat, (10) Vaskulitis serebral seperti arteritis temporal, arteritis Takayasu, polyarteritis nodosa (PAN), Wegener’s granulomatosis, (11) Systemic lupus erythematosus (SLE), (12) Cerebral autosomal dominant arteropathy with subcortical infarcts
and leucoencephalopathy (CADASIL), (13) Fabry’s disease, dan (14) Trombofilia. Khusus pada wanita usia muda, beberapa faktor risiko lainnya antara lain: (1) Penggunaan kontrasepsi oral terutama pada wanita perokok, migren dengan aura, dan hipertensi; (2) Kehamilan, terutama jika terdapat preeklampsi, eklampsi, dan sindrom HELLP (hemolysis, elevated liver enzymes, and low platelets). Stroke pada usia muda memiliki karakteristik tersendiri, sehingga membutuhkan pendekatan yang berbeda. Faktor risiko perlu diidentifikasi untuk penatalaksanaan dan pencegahan terjadinya stroke berulang. Penelitian berbasis populasi dengan metodologi yang baik penting untuk lebih mengetahui besaran masalah stroke pada usia muda.Nearly 10 % strokes occur at a relatively young age (less than 45 years old). The incidence of stroke in under 45 year-old is between 7-15 cases/100,000 persons/year and 1-8 cases /100,000/year in children. Disorders or diseases related or suspected as risk factors are: (1) Migraine, (2) Sickle - cell disease, (3) Heart disease, (4) Cerebral blood vessels abnormality,
Perbandingan Adductor Canal Block Dan Femoral Nerve Block Terhadap Kekuatan Otot Quadriceps Femoris Pascaoperasi Total Knee Replacement Eva Srigita Tari; Iwan Fuadi; M Andy Prihartono
Jurnal Anestesi Perioperatif Vol 10, No 2 (2022)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v10n2.2428

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Abstrak Blokade saraf femoral telah digunakan terlebih dahulu dalam penatalaksanaan nyeri pascaoperasi total knee replacement (TKR). Penelitian ini bertujuan mengetahui perbedaan kekuatan otot paha pascaoperasi TKR antara femoral nerve block (FNB) dan adductor canal block ACB dengan mengukur nilai manual muscle test (MMT), selain itu penelitian ini membandingkan nilai numeric rating scale (NRS) dengan total kebutuhan patient controlled anlagesia (PCA) morfin yang digunakan pascaoperasi TKR. Penelitian dilakukan pada periode Oktober–November 2020 di RS Santosa Bandung. Penelitian ini menggunakan metode uji klinis acak terkontrol buta tunggal melibatkan 18 pasien yang menjalani operasi TKR. Pasien dibagi menjadi dua kelompok, kelompok kelompok ACB, n=9 dan kelompok FNB, n=9. Pemeriksaan MMT otot kuadrisep femoris dilakukan pada jam ke-24 pascaoperasi TKR. Analisis data numerik dengan uji T tidak berpasangan dan Mann Whitney. Data kategorik dengan uji chi square. Nilai NRS ACB lebih tinggi pada jam ke- 24 saat diam dan bergerak serta total kebutuhan PCA morfin lebih tinggi pada kelompok ACB, namun tidak bermakna secara statistik (p>0,05). Nilai MMT pascaoperasi TKR pada jam ke-24 pada kelompok ACB lebih tinggi dibanding dengan kelompok FNB dengan perbedaan bermakna (p<0,05). Adductor canal block sebagai modalitas penatalaksanaaan nyeri pascaoperasi total knee replacement memberikan efek analgetik yang tidak berbeda dengan femoral nerve block, namun lebih baik memulihkan kekuatan motorik otot kuadrisep femoris yang dibuktikan  dengan penilaian MMT yang lebih baik. Comparison of Adductor Canal Block and Femoral Nerve Block with Quadriceps Femoris Muscle Strength PostoperativeTotal Knee Replacement Femoral nerve blocks (FNB) were previously used in pain management post-total knee replacement (TKR). This study aimed to determine the differences in thigh muscle strength post-TKR surgery between patients with FNB and adductor canal block (ACB) by measuring manual muscle tests (MMT). In addition to MMT scores, this study also compared the NRS scores and total patient-controlled analgesia (PCA) of morphine required post-TKR surgery. The study was conducted in October-November 2020 at Santosa Hospital, Bandung. The study was a controlled, randomized, blinded study of 18 patients who underwent TKR surgery. Patients were divided into two groups, one ACB group, n=9, and one FNB recipient group, FNB n=9. Next, an MMT examination of the quadriceps femoris muscle was performed 24 hours post-TKR surgery. Numerical data were analyzed using the unpaired T-test and Mann-Whitney test. Categorical data using chi-square test. MMT measurements in the ACB group were higher than in the FNB group at 24 hours (p), whereas NRS scores in the ACB group were higher at 24 hours when idle and with movement. The total PCA morphine required was higher in the ACB group but was not statistically significant. MMT examination in postoperative TKR patients was better in ACB patients compared to FNB patients. Adductor canal block as a postoperative pain modality in total knee replacement procedure provides a similar analgesic effect as a femoral nerve block. However, it is better in restoring motor strength of the quadriceps femoris muscle, as evidenced by a better assessment of MMT.
Gambaran Respons Peserta PPDS Anestesi FK Unpad Terhadap Pernyataan Seputar COVID-19 dan Tatalaksana Jalan Napas Pasien COVID-19 Hansen Wangsa Herman; Iwan Fuadi; Radian Ahmad Halimi
Jurnal Anestesi Perioperatif Vol 10, No 2 (2022)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v10n2.2631

Abstract

Peserta Program Pendidikan Dokter Spesialis (PPDS) Anestesi adalah salah satu tenaga kesehatan yang rentan terinfeksi Coronavirus disease 2019 (COVID-19) yang disebabkan oleh paparan droplet dan aerosol saat mereka mengerjakan prosedur tata laksana jalan napas pasien. Tujuan penelitian ini adalah menggambarkan bagaimana respons peserta PPDS anestesi Fakultas Kedokteran Universitas Padjadjaran (FK Unpad) terhadap pernyataan seputar COVID-19 dan tata laksana jalan napas pada pasien COVID-19. Penelitian ini adalah sebuah studi deskriptif dengan desain potong lintang.  Pengambilan data secara survei daring yang dilakukan kepada sebanyak 98 peserta PPDS Anestesi bulan Oktober 2021. Data penelitian terdiri atas karakteristik partisipan, respons terhadap pernyataan seputar COVID-19, dan tata laksana jalan napas pasien COVID-19. Data kemudian dianalisis dengan metode statistika deskriptif dengan aplikasi SPSS versi 26. Hasil penelitian ini adalah mayoritas peserta PPDS anestesi FK Unpad menunjukkan respons yang sesuai dengan referensi yang ada kecuali respons terhadap pernyataan mengenai periode inkubasi, lokasi pemeriksaan praoperatif, karantina setelah intubasi, dan masker laring sebagai pilihan pertama pembukaan jalan napas, dan pemberiaan pra-medikasi bagi pasien COVID-19 yang akan dianestesi. Simpulan penelitian ini adalah walaupun mayoritas peserta PPDS Anestesi FK Unpad sudah memberikan respons yang sesuai, namun masih diperlukan peningkatan literasi mengenai COVID-19, dan tata laksana jalan napas pasien COVID-19 agar mereka semakin aman dalam pekerjaannya. Responses of Universitas Padjadjaran Anesthesiology Residents to COVID-19 and Airway Handling for COVID-19 PatientsAnesthesiologists are healthcare workers vulnerable to COVID-19 infection as they are exposed to droplets and aerosols when working with patients' airways. This study aimed to describe how anesthesiology residents of the Faculty of Medicine, Universitas Padjadjaran responded to statements about COVID-19 and airway management in COVID-19 patients. This research was a descriptive study with a cross-sectional design. Data were collected through an online survey of 98 anesthesiology resident participants in October 2021. The data collected consisted of participant characteristics, responses to statements about COVID-19, and airway management of COVID-19 patients. Data analysis used descriptive statistical methods using the SPSS version 26 application. Study results were: most of the participants showed an appropriate response according to existing references except for responses to statements regarding the incubation period, preoperative examination location, quarantine after intubation, and laryngeal mask as the first choice to establish an airway, and providing premedication for COVID-19 patients who would be anesthetized. This study concludes that although most participants have responded appropriately, they must increase literacy about COVID-19 and the airway management of COVID-19 patients to remain secure at work. 
THE DISEASE PATTERN OF ELDERLY PATIENTS ADMITTED IN THE NEUROLOGY WARD OF HASAN SADIKIN GENERAL HOSPITAL Millata Azma Basmala; Cep Juli; Paulus Anam Ong; Nushrotul Lailiyya; Lisda Amalia
MNJ (Malang Neurology Journal) Vol. 9 No. 1 (2023): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2023.009.01.3

Abstract

Background: As life expectancy continues to increase, the elderly population in Indonesia has significantly doubled in the last five decades, making Indonesia a home to 4th largest population of elderly people in Asia. Unlike other age group, there are more challenges in handling older persons due to their increased mortality, morbidity, and disability risks. Objective: We performed this study to understand the disease pattern in elderly patients admitted in the neurology ward of Hasan Sadikin General Hospital. Methods: This was a descriptive cross-sectional study using data from medical resume. We included medical resume of elderly patients admitted in the neurology ward of Hasan Sadikin General Hospital from January 2015 to December 2019. All incomplete, lost, or inaccessible medical resumes were excluded. Results: Among a total of 400 subjects, 210 (52.5%) were males and 190 (47.5%) were females. Young old (59,5%) presented to be the most observed age group. The most frequent diseases of elderly patients seen in this study were ischemic stroke (55.3%), followed by hemorrhagic stroke (19.5%), subarachnoid hemorrhage (5.3%), and tetanus (4.5%). Atherothrombotic subtype (50,6%) of ischemic stroke was seen to be the most frequent. Conclusion: Noncommunicable diseases were the majority of all cases in the elderly with cerebrovascular diseases, such as stroke and subarachnoid haemorrhage, as the most common conditions. It is important to develop efficient hospital-based management strategies particularly for these diseases and intensify early detection and management of risk factors.
CLINICAL OUTCOME OF STROKE PATIENTS BASED ON THE NATIONAL INSTITUTES OF HEALTH STROKE SCALE (NIHSS) IN A TERTIARY HOSPITAL Liunardo Bintang Pratama; Lisda Amalia; Cep Juli; Uni Gamayani; Asep Nugraha Hermawan
MNJ (Malang Neurology Journal) Vol. 9 No. 1 (2023): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2023.009.01.4

Abstract

Background: Stroke is the second leading cause of death and the third cause of disability globally. Clinical outcomes caused by stroke are varied and influenced by various factors. Objective: This study aims to describe the clinical outcome of stroke patients based on neurological deficit using NIHSS at Dr. Hasan Sadikin General Hospital, Bandung. Methods: This study is a retrospective descriptive, cross-sectional study using secondary data from medical records recruited between January 2019 – December 2019 at the Department of Neurology Dr. Hasan Sadikin General Hospital Bandung with the total sampling method. Variables include demographic data, risk factors, and clinical characteristics. Neurological deficit was assessed using NIHSS. Data were analyzed and presented in the form of tables. Results: There were 202 subjects eligible for this study, including ischemic (71.8%) and intracerebral hemorrhage (28.2%) stroke patients. Most of the subjects were male (53%), aged ≥60 years (50,5%), presenting with onset >6 hours (72.3%), and had hypertension (92,1%). Most of the subjects have a moderate stroke (n=102;50.5%) based on the NIHSS score at admission and mild stroke (n=117;57.9%) based on the NIHSS score at discharge, with a motor deficit as the most common neurological deficit found. Conclusion: The majority of stroke patients presented with a moderate stroke on admission and had a clinical improvement during hospital treatment, with most of the patients experiencing a mild stroke on discharge based on NIHSS score. The motor deficit is the most common neurological deficit that affects clinical outcomes.
Characteristics and Risk Factors of Patients with Acute Ischemic Stroke in Dr. Hasan Sadikin General Hospital Bandung, Indonesia Nesyia Tara Restikasari; Uni Gamayani; Lisda Amalia; Sofiati Dian; Aih Cahyani
Althea Medical Journal Vol 9, No 4 (2022)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v9n4.2362

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Background: Stroke is the second most common cause of death globally and the third most common cause of disability. The prevalence of stroke is increasing despite managing various stroke risk factors that have improved considerably. Ischemic stroke is the most prevalent type, and about 90% of stroke events are attributable to modifiable risk factors. This study aimed to explore the characteristics and risk factors of patients with acute ischemic stroke in Dr. Hasan Sadikin General Hospital.Methods: A descriptive cross-sectional study was conducted retrospectively in October 2020, using a total sampling method on medical records of acute ischemic stroke patients in Dr. Hasan Sadikin General Hospital year 2019. Medical records with incomplete and missing data were excluded. Demographic and known risk factors data were collected and presented in the table.Results: Of the 355 subjects, male patients (n=69, 76.7%) were predominant, with the age range of 55–64 years old (36.1%). The majority of the subjects had an ischemic stroke of large-artery atherosclerosis (68.2%) with carotid system involvement (93.2%). As much as 305 subjects (85.9%) had hypertension as the risk factor, followed by dyslipidemia (47.3%), heart disease (39.4%), previous stroke history (33.8%), smoking (25.6%), diabetes mellitus (24.5%), hyperuricemia (12.1%), and blood disorders (2.3%).Conclusions: Males in the older age group have a higher risk of getting acute ischemic stroke with ischemic stroke of large-artery atherosclerosis and carotid system involvement, and hypertension has the highest prevalence.
Hiperkapnia Sebagai Prediktor Mortalitas Pasien COVID-19 di Ruang Rawat Intensif Indra Wijaya; Ezra Oktaliansah; M. Erias Erlangga; Iwan Fuadi; Erwin Pradian; Indriasari Indriasari
Jurnal Anestesi Perioperatif Vol 10, No 3 (2022)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v10n3.3048

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Virus SARS-CoV-2 menyebabkan penyakit pernapasan akut yang disebut COVID-19 dan menyebabkan pandemi global. Proses aktivasi trombosis intravaskular pada COVID-19 menyebabkan komplikasi trombosis mikrovaskular dan makrovaskular sehingga terjadi peningkatan ruang mati paru dan meningkatkan kadar PaCO2. Hiperkapnia menyebabkan banyak perubahan fisiologis dalam tubuh meliputi sirkulasi paru dan sistemik dan meningkatkan risiko mortalitas pasien ARDS. Penelitian ini bertujuan mengetahui apakah hiperkapnia merupakan prediktor mortalitas pasien COVID-19. Penelitian dilakukan berdasarkan data pasien pada periode Maret 2020–Desember 2021. Penelitian ini adalah penelitian analitik observasional dengan rancangan kohort retrospektif. Data PaCO2 pasien diambil saat hari pertama pasien dirawat di ICU RSUP Dr. Hasan Sadikin dan status mortalitas pasien di hari rawat ke-7 dan 28 hari. Analisis statistik yang digunakan adalah analisis bivariabel simple regression logistic. Hasil analisis statistik diperoleh nilai p< 0,05 dengan OR = 7,07 (CI 2,519–19,850) pada mortalitas hari ke-7, dan nilai p< 0,05 OR 44,33 (CI 9,182–214,062) pada mortalitas hari ke-28. Simpulan penelitian ini menunjukkan bahwa hiperkapnia merupakan prediktor mortalitas hari ke-7 dan ke-28 perawatan pada pasien COVID-19 yang dirawat di ruang rawat intensif isolasi.Hypercapnia as Mortality Predictor in COVID-19 PatientsThe SARS-CoV-2 virus causes COVID-19, an acute respiratory illness that caused a global pandemic. The activation of intravascular thrombosis in COVID-19 results in microvascular and macrovascular thrombosis complications, which increase lung dead space and PaCO2 levels. The hypercapnia condition causes many physiological changes in the body, including pulmonary and systemic circulation. It is known to increase the mortality risk in ARDS patients admitted to the Intensive Care Unit (ICU). This study aimed to determine if hypercapnia was a mortality predictor in COVID-19 patients treated in the isolation intensive care unit at Hasan Sadikin Hospital in Bandung. This observational analytic study used an observational analytic design with a retrospective cohort. The patient's PaCO2 data was collected on the first day of hospitalization in the ICU, and the patient's mortality status was collected on the 7th and 28th days of hospitalization. According to the statistical analysis, hypercapnia was associated with higher mortality, OR 7.07 (CI 2.519–19.850) on the 7th-day mortality and 44.33 (CI 9.182–214.062) on the 28th-day mortality, P value < 0.05. In conclusion, hypercapnia is a mortality predictor on the 7th and 28th days of treatment in COVID-19 patients treated in the isolation intensive care unit. 
Clinical Features and Outcomes of Patients with Tetanus at Dr. Hasan Sadikin General Hospital Bandung 2015–2019 Ananda Pratama Kesumaningtyas Gunawan; Ahmad Rizal Ganiem; Siti Aminah; Lisda Amalia; Sofiati Dian
Althea Medical Journal Vol 9, No 3 (2022)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v9n3.2299

Abstract

Background: Tetanus is a disease characterized by painful muscle spasms all over the body, which still becomes an important health issue worldwide, particularly in developing countries due to the high mortality rate. The clinical features also affect the mortality rate of adult tetanus patients. Tetanus severity score (TSS) is a prognostic scoring system developed in Vietnam that uses clinical features to predict the mortality rate in adult tetanus patients. The aim of this study was to describe the clinical features and outcomes of adult tetanus patients using TSS.Methods: A descriptive, cross-sectional study with a total sampling method was conducted between 2015 and 2019. A total of 71 medical records of adult generalized tetanus patients in the Department of Neurology Dr. Hasan Sadikin General Hospital Bandung were collected to analyze the clinical features and outcomes using TSS. Statistical analysis was performed using SPSS software ver. 25.0.Results: Among seventy-one tetanus patients, 62 (87.3%) were male, and the average age was 55.2±11.2 years. More than half of the patients (71%) were having grade III or worse and experienced dysautonomia complications (57.7%). The mortality rate was 38% and those who survived at discharge, 88.64% had TSS score <8, whereas 37.04% who died had TSS score ≥8.Conclusions: Tetanus in Bandung has a high mortality rate. Those who have died have high TSS scores, while the survivors have low TSS scores, suggesting that the TSS is a prospective scoring to predict the mortality rate in patients with tetanus in Indonesia.
PATTERN OF ANTICOAGULANT THERAPY IN CARDIOEMBOLIC STROKE Reihan Achmad Reza; Lisda Amalia; Nushrotul Lailiyya Dahlan; Cep Juli; Hanna Goenawan
MNJ (Malang Neurology Journal) Vol. 9 No. 2 (2023): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2023.009.02.11

Abstract

Background: Cardioembolic stroke is a category of ischemic stroke that manifests more severe, is prone to recurrence, and is related to a higher mortality rate than the other categories of ischemic stroke. Anticoagulant therapy is recommended in cardioembolic stroke, both for primary and secondary prevention. Objective: The objective of this study is to understand the pattern of anticoagulant therapy in cardioembolic stroke patients admitted at Hasan Sadikin General Hospital Bandung. Methods: The methodology of this study uses retrospective descriptive cross-sectional and use data from medical records collected during January 2015 to December 2020 at Neurology Department of Hasan Sadikin General Hospital with total sampling method. The inclusion criteria were cardioembolic stroke patients that received anticoagulant therapy. Anticoagulant therapy was stratified into Warfarin and New Oral Anticoagulants (NOACs) which consist of dabigatran, rivaroxaban, and edoxaban. To assess stroke severity outcome between warfarin and NOACs we use the National Institutes of Health Stroke Scale (NIHSS) Score. Results: From the 162 cardioembolic stroke patients, the most common oral anticoagulant used was warfarin (90.12%), followed by dabigatran (4.94%), rivaroxaban (3.70%), and edoxaban (1.23%). Only 1 (0.62%) patient who experienced complications from anticoagulant therapy, the complication was non-major bleeding and occurred in warfarin users. Both warfarin and NOACs mainly had NIHSS on discharge in a moderate category with the mean of NIHSS 7.615 and 7.276 for warfarin and NOACs respectively. Conclusion: Warfarin is the most common oral anticoagulant used for cardioembolic stroke based on this study. Both warfarin and NOACs groups have similar stroke severity outcomes measured by NIHSS on discharge and NOACs have lower incidence of bleeding compared to warfarin group.
Co-Authors - Elvidiansyah - Elvidiansyah A Himendra Wargahadibrata A Himendra Wargahadibrata A. Muthalib Nawawi A.A. Ketut Agung Cahyawan W Abdul Muthalib Nawawi Abdul Muthalib Nawawi Abdul rachman, Iwan Abdul Rahman Adnin Nugroho Adriana Damayanti Afdi Arahim Putra Agnes Rengga Indrati Agus Susanto Agusti Setiabudi Pramata Ahmad Doni ahmad doni Ahmad Rizal Ahmad Rizal Ahmad Rizal ahmad rizal Ahmad Rizal Ganiem Ahmad Rizal Ganiem, Ahmad Rizal Aih Cahyani Aisyah Ummu Fahma Al Rasyid Amanda Diannisa Azzahra Amany Khansa Amaylia Oehadian Aminuyati Anam Ong Anam Ong Ananda Pratama Kesumaningtyas Gunawan Andi Basuki Prima Birawa Andi Basuki Prima Birawa Andi Basuki Prima Birawa Andre Aditya Andre Tanuwijaya, Andre Andy Hutariyus Anindyta Murfia Khairunnisa Ardhana Risworo Anom Yuswono Ardhana Risworo Anom Yuswono Ardi Zulfariansyah Ardi Zulfariansyah Ardi Zulfariansyah Ardiana Ari Saptadi Ari Saptadi Aries Saifudin Ariestian, Erick Army Zaka Anwary, Army Zaka Arna Fransisca Arsy Felisita Dausawati Arsy Felisita Dausawati Arviana Adamantina Putri Asep Nugraha Hermawan Asep Nugraha Hermawan Asep Nugraha Hermawan Asyer Asyer Ayu, Auliya Putri Badriyah, Nur’aini Jamilatul Berliana, Sobaryati Biben, Vitriana Bisri, Tatang https://scholar.google.co.id/citations?u Bramantyo Pamugar Calista, Chandra Cep Juli Chandra Calista Citra Windani Mambang Sari Dedi Fitri Yadi Defri Aryu Dinata Defri Aryu Dinata, Defri Aryu Dessy Sutoyo Dewi Ramadani Dewi Ramadani Dewi Yulianti Bisri Dian Novitasari Doddy Tavianto Dzulfikar D. L. Hakim Eka Damayanti Eko Nofiyanto Eppy Buchori Eppy Buchori Aristiady Eri Surahman Eri Surahman Erick Ariestian Erwin Pradian Eva Srigita Tari Ezra Oktaliansah Fadila Arsanti Fahma, Aisyah Ummu Fauzan Musyaffa Fifi Veronica Firdaus, Riyadh Fithrah, Bona Akhmad Fithrah, Bona Akhmad Fitri Sepviyanti Sumardi Fitri Yanti Gaga Irawan Nugraha Galuh Saputri Ginna Megawati Glenn Mark Togu Gloria Kartika Gunadharma, Suryani Guntur Darmawan Hamzah Hamzah Hanna Goenawan Hanna Goenawan Hansen Wangsa Herman Haqun Baitika Harahap, M Sofyan Harry Galuh Nugraha Hartiah Haroen Hermawan, Asep Nugraha Hidayat, Dede A Hidayat, Faqih Hidayat, Shaffana Hilman Hilman Hunter D. Nainggolan Hunter D. Nainggolan Ida Parwati Ike Sri Redjeki Ike Sri Redjeki Indra Wijaya Indriasari Indriasari Islami, Aditya Iwan Abdul Rachman Jerico Franciscus Pardosi Jimmy Setiadinata Jimmy Setiadinata, Jimmy Jonathan Jeremi Siagian Kartapraja, Roni D. Kartika, Gloria Khairunnisa, Shafa Ayu Khofifah Nurfaisah Lailiyya, Nushrotul Laniyati Hamijoyo, Laniyati Lee Shok Chen Lee Shok Chen, Lee Shok Leni Lismayanti Liunardo Bintang Pratama Lukman Hidayat Lulu Eva Rakhmilla, Lulu Eva M Andy Prihartono M. Erias Erlangga M. Erias Erlangga, M. Erias Maharani, Nurmala Dewi Mariko Gunadi Mariko Gunadi Marina A. Moeliono Marina A. Moeliono, Marina A. Martaria, Nency Martinus, Fardian Martinus, Fardian Maulana Muhammad Maulana Muhammad, Maulana Mayasari, Ferra Mayasari, Ferra Millata Azma Basmala Muhammad Adjie Pratama Muhammad Mustofa Ramadhan Nadya, Siti Fairuz Nandina Oktavia Nani Kurniani Nesyia Tara Restikasari Neti Juniarti Nur Atiik Nurmin, Rahmawati Nurohman Nushrotul Lailiyya Nushrotul Lailiyya Nushrotul Lailiyya Dahlan Oktivia, Wenny Ong, Paulus Anam Pamugar, Bramantyo Pandji Irani Fianza Paranita Utama Paulus Anam Ong Paulus Anam Ong Paulus Anam Ong Pison, Osmond Muvtilof Pramodana, Bintang Prihatno, M. Mukhlis Rudi Putri, Dini Handayani R, Tubagus Yuli R, Tubagus Yuli Radian Ahmad Halimi Rahmadsyah, Teuku Rahmatisa, Dimas Rahordjo, Sri Ramdan Panigoro Reihan Achmad Reza Reza W. Sudjud Ria Bandiara Richard Pahala Sitorus Rico Defryantho,* Lisda Amalia,* Ahmad Rizal,** Suryani Gunadharma,* Siti Aminah,* Nushrotul Lailiyya* Rini Rustini Rita Arsika Fauziah Riyadh Firdaus Rizkia, Fildza Intan Rizky Gimnastiar Roni D. Kartapraja Rudi Kurniadi Kadarsah Ruli Herman Sitanggang S, Achmad Afif Saleh, Siti Chasnak Saleh, Siti Chasnak Saprudin Saprudin Saputra, Gilang Nispu Sari, Kartika Indah Setiawan Setiawan Shenny Dianathasari Santoso Sidabutar, Berliana Sitanggang, Ruli H. Siti Aminah Siti Aminah Siti Aminah Siti Aminah Siti Aminah Siti Aminah Sobana Siti Nur Fatimah Sitorus, Richard Pahala Siuliyanty, Siuliyanty Sobaryati Sobaryati Sobaryati Sobaryati Sobaryati, Sobaryati Sofiati Dian Sri Rahardjo Sri Rahardjo Sudadi Sudadi Sukmawati, Rani Suryadi Suryadi Suryani Gunadharma Suryani Gunadharma Suryani Gunadharma Sutoyo, Dessy Suwarman, S Suwarman, S Syifa, Nadia Syifa, Nadia Tantarto, Tamara Tatang Bisri Tatang Bisri Theresia C. Sipahutar Theresia C. Sipahutar Theresia Monica Rahardjo Thomas Thomas Tiara Pramaesya Tiene Rostini, Tiene Tinni T. Maskoen Tinni T. Maskoen Tinni T. Maskoen Trislawati, Cristina Trully Deti Rose Sitorus Uni Gamayani Uni Gamayani Uni Gamayani Uni Gamayani Uni Gamayani Uni Gamayani Uni Gamayani Uni Gamayani Uni Gamayani, Uni Vania Angeline Bachtiar Verolia Yunita Putri Wandira, Rega Dwi Wardhani, Ildzamar Haifa Wardoyo, Chandra Calista Wargahadibrata, A. Hmendra Wargahadibrata, A. Hmendra Widiastuti, Monika - Wildan Firdaus Wirayuga Rizkia Suwahyo Yovita Stevina Yunita Susanto Putri Yunita Susanto Putri Yusuf Wibisono Yusuf Wibisono Zamzami, Nyiemas Moya Zamzami, Nyiemas Moya