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All Journal Jurnal Kedokteran Syiah Kuala Jurnal Berkala Epidemiologi Jurnal NERS Indonesian Journal of Tropical and Infectious Disease Jurnal Biometrika dan Kependudukan (Journal of Biometrics and Population) Sari Pediatri Paediatrica Indonesiana Molecular and Cellular Biomedical Sciences (MCBS) Jurnal Gizi Klinik Indonesia Jurnal Keperawatan Muhammadiyah Journal of Maternal and Child Health INTERNATIONAL JOURNAL OF NURSING AND MIDWIFERY SCIENCE (IJNMS) Jurnal Respirasi (JR) Jurnal Gema Ngabdi Biomolecular and Health Science Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Community Development Journal: Jurnal Pengabdian Masyarakat Majalah Biomorfologi (Biomorphology Journal) CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Indian Journal of Forensic Medicine & Toxicology INDONESIAN MIDWIFERY HEALTH AND SCIENCES JOURNAL PROFESSIONAL HEALTH JOURNAL Journal of Multidisciplinary Applied Natural Science KESANS : International Journal of Health and Science Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Jurnal Indonesia Sosial Sains Jurnal Keperawatan JUKEJ: Jurnal Kesehatan Jompa Jurnal Vokasi Keperawatan (JVK) Jurnal Widya Medika Folia Medica Indonesiana
Dominicus Husada
Departemen Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Airlangga
Agriculture, Biological Sciences & Forestry Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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The Association Between Maternal Knowledge of Immunization and Acceptance of Multiple Injection Immunization at Community Health Posts in an Urban Primary Healthcare Setting Sabrina, Haifa Rafiqa; Husada, Dominicus; Ningtyas, Woro Setia; Lestari, Pudji
Jurnal KESANS : Kesehatan dan Sains Vol 5 No 4 (2026): KESANS: International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v5i4.544

Abstract

Introduction: Multiple injection immunization is a service strategy that administers more than one vaccine in a single visit to improve immunization efficiency and coverage. Despite evidence of safety, parental concerns regarding adverse effects remain a major barrier to its acceptance. Maternal knowledge plays a critical role in decision-making related to childhood immunization. Objective: This study aimed to analyze the association between maternal knowledge of immunization and acceptance of multiple injection immunization at community health posts in an urban primary healthcare setting. Method: An analytical observational study with a cross-sectional design was conducted among 82 mothers with children aged 2–24 months, selected using purposive sampling. Data were collected using structured questionnaires and analyzed using the Chi-square test. Result and Discussion: More than half of respondents demonstrated a high level of immunization knowledge (57.3%), and the majority accepted multiple injection immunization (68.3%). Among mothers who accepted multiple injections, 67.9% had a high knowledge level. Statistical analysis showed a significant association between maternal knowledge level and acceptance of multiple injection immunization (p = 0.001). Conclusions: Maternal knowledge of immunization is significantly associated with acceptance of multiple injection immunization. Strengthening educational interventions targeting mothers and families is essential to improve acceptance and sustain optimal immunization coverage.
Genetic Diversity and Multiplicity of Plasmodium falciparum Infection in Southeast Asia: New Insights from a Systematic Review Praswitasari, Rengganis; Husada, Dominicus; Hasan, Nur Aini; Adnyana, I Made Dwi Mertha
Journal of Multidisciplinary Applied Natural Science Articles in Press
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/jmans.2774-3047.357

Abstract

Plasmodium falciparum caused four million new malaria cases in Southeast Asia in 2023, with heterogeneous transmission patterns and the development of artemisinin resistance. The merozoite surface protein genes (msp-1 and msp-2) serve as genetic markers for analyzing the parasite population structure and multiplicity of infection (MOI). However, a comprehensive synthesis of regional data is limited. This study aimed to determine the genetic diversity and MOI of P. falciparum in Southeast Asia. This systematic review was guided by PRISMA guidelines with searches in the Scopus, PubMed, ProQuest, and Google Scholar databases (2014–2024). The inclusion criterion was observational studies, analyzing the genetic diversity of P. falciparum via msp-1 and msp-2 markers in Southeast Asia. The extracted data included the frequency of msp-1 and msp-2 family alleles, the prevalence of polyclonal infections, and the mean MOI value. Quality assessment was performed via the joanna briggs institute critical appraisal tools with narrative synthesis following the synthesis without meta-analysis (SWiM) guidelines. Fifteen studies; Indonesia (40%), Thailand (26.67%), Myanmar (20%), Vietnam and Malaysia (6.66%) with 1,830 samples successfully genotyped from 2,130 collected samples. The MAD20 (msp-1) allele dominated most locations, with frequencies of up to 100% in Lampung. The distribution of msp-2 alleles showed geographical variation, with FC27 dominating in Papua (96.2%) and 3D7/IC in Vietnam (97.0%). The prevalence of polyclonal infection ranged from 0-84.6%, with MOI values ranging from 1.0-2.93. The hyperendemic areas presented high MOIs (>2.0), whereas the hypoendemic areas presented MOIs close to 1.0, confirming a positive correlation with malaria transmission intensity. The P. falciparum population in Southeast Asia shows high genetic diversity, with geographically variable allele distribution patterns, and MOI values are correlated with malaria endemicity levels. These findings support the need for regional molecular surveillance and a polyvalent approach to the development of msp-based vaccines.
Hubungan Imunisasi Dasar Lengkap dengan Kejadian Pneumonia pada Balita di Indonesia Tahun 2020-2025: Studi Literatur Nugraheny, Risca Ayu; Ferdinandus, Euvanggelia Dwilda; Husada, Dominicus; Sulistiawati, Sulistiawati
JUKEJ : Jurnal Kesehatan Jompa Vol 5 No 1 (2026): JUKEJ: Jurnal Kesehatan Jompa
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/jkj.Vol5.Iss1.2447

Abstract

Pneumonia merupakan salah satu penyebab utama morbiditas dan mortalitas pada balita di Indonesia, dengan angka kematian mencapai 19.000 kasus pada tahun 2018. Penelitian ini bertujuan untuk menganalisis hubungan antara kelengkapan imunisasi dasar dengan kejadian pneumonia pada balita melalui studi literatur. Penelusuran dilakukan pada Google Scholar, DOAJ, dan ResearchGate, dengan kriteria artikel yang diterbitkan tahun 2020-2025. Sebanyak 10 artikel yang memenuhi kriteria dianalisis secara deskriptif naratif untuk mengidentifikasi pola hubungan antara imunisasi dasar lengkap dan risiko pneumonia. Hasil kajian menunjukkan bahwa balita dengan imunisasi dasar tidak lengkap memiliki risiko lebih tinggi mengalami pneumonia dibandingkan balita yang telah menerima imunisasi lengkap, khususnya melalui vaksin DPT, Hib, dan Campak. Efektivitas imunisasi dipengaruhi oleh faktor tambahan seperti status gizi, pemberian vitamin A, pemberian ASI eksklusif, dan kondisi lingkungan rumah. Temuan ini menegaskan pentingnya strategi pencegahan pneumonia yang bersifat komprehensif, mengintegrasikan pemberian imunisasi lengkap, perbaikan gizi, promosi ASI eksklusif, serta peningkatan kualitas lingkungan. Secara praktis, hasil penelitian dapat menjadi acuan dalam pengembangan program intervensi yang melibatkan keluarga, tenaga kesehatan, dan masyarakat untuk menurunkan kejadian pneumonia pada balita secara efektif..
Profil Isolat Corynebacterium diphtheriae Toksigenik di Jawa Timur Tahun 2012-2017 Sugi Deny Pranoto Soegianto; Adi Pramono Hendrata; Eveline Irawan; Ismoedijanto; Dominicus Husada
Majalah Kedokteran Indonesia Vol 69 No 2 (2019): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.69.2-2019-75

Abstract

Introduction: Diphtheria has been reported as an outbreak in some regions inIndonesia, most of the cases are from East Java.Objective: To describe the profile of toxigenic Corynebacterium diphtheriaeisolates in East Java. Methods. An descriptive study from August 20th -November 30th, 2018. Isolates was selected by cluster random sampling. The viability and toxigenicity testwere done in BBLK Surabaya. Viable and toxigenic isolates were done forcharacteristic analysis. Result: A total of 114 isolates, 6 were non-viable, 108 were viable and toxi-genic. The majority of the hosts were male (58,3%), median age 6,5-year-old(minimum 1, maximum 14-year-old), 50% from the 1-5-year-old age group. Highest origin of isolates from patients (78,7%) rather than carriers (21,3%).The most isolates from Madura (47,2%) and horseshoe area (20,4%). Most ofthem (74.1%) were taken from a pharyngeal swab rather than a nasal swab(25,4%). Mitis was 76,9% and gravis was 23,1%. Conclusion: In this study, the majority of toxigenic Corynebacterium diphtheriae were found in the 1-5-year-old age group and most of them domi-cile in Madura and horseshoe area. Most of the isolates were taken from apharyngeal swab of patients. Mitis was the major variant.
Faktor Risiko Kelahiran Prematur di RSUD Dr. M. Soewandhi Surabaya pada Tahun 2017 Bulqis Inas Sakinah; Dominicus Husada; Sulistiawati Sulistiawati
Majalah Kedokteran Indonesia Vol 69 No 12 (2019): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, V
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.69.12-2019-165

Abstract

Introduction: Preterm labor is one of the biggest direct cause of neonatal death and determined by various risk factors. Objective: To determine the effect of mother’s age, parity, preterm labor history, multiple pregnancy and pregnancy complications on the incidence of preterm labor. Method: Retrospective case-control method was conducted. Data were obtained from medical records of mothers who did labor in RSUD Dr. M. Soewandhi in 2017. Result: The analysis showed significant relationship between mother’s age (p=0,004), preterm labor history (p=0,006) and pregnancy complications (p less than 0,001) with the incidence of preterm labor. Based on multivariate analysis, mothers aged less than sign 20 and greater than sign dari 35 years old and those who had pregnancy complications were at risk of 3,510 (95% CI 1,481-8,230) and 5,203 (95% CI 2,248-12,040) times of having preterm labor.Conclusion: Maternal age and pregnancy complications were two contributing factors that increase the risk of preterm labor. These factors should be given special attention while assessing pregnancy to prevent preterm labor.
Vaksin SARS-CoV-2: Tinjauan Kepustakaan Dominicus Husada
Majalah Kedokteran Indonesia Vol 70 No 10 (2020): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, V
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.70.10-2020-254

Abstract

The pandemic of Systemic Acute Respiratory Syndrome-coronavirus-2 (SARS-CoV-2) could not be stopped until mid-June 2020. The difficulty in finding a panacea for this disease made the vaccine very valuable. At present there are more than 100 vaccine candidates worldwide, with at least 10 have begun undergoing clinical trials in humans. The vaccine at its farthest stage is from the University of Oxford, which has entered phase 3. There are multiple approaches in vaccine research, and some methods have never been used before. Some of the vaccines in the study were originally intended for the previous SARS-CoV and Middle East Respiratory Syndrome-coronavirus (MERS-CoV). The main target in general is the protein spike S. Several obstacles need to be considered, such as the absence of a vaccine for the corona virus, the antibody-dependent enhancement (ADE) mechanism, and the possibility of immunopotentiation. In Indonesia there are 4 teams with vaccine research, and 3 other companies that work with international institutions abroad to directly enter the clinical trial phase 2 or 3. After the vaccine has been found, it is necessary to guarantee equality in gaining access among various countries.
Co-Authors A’yuni, Zera Qurrota Adi Pramono Hendrata Adnyana , I Made Dwi Mertha Aflahudin, M. Ahda Naufal Agung Dwi Wahyu Widodo Ahmad Suryawan Akbar Panjinegara, Muhammad Alfi Layali Muntaza Anang Endaryanto Andi Airina Binti A Agus Annisa Fira Salsabila Arguni, Egi Ari Prayitno Ari Prayitno, Ari Arien Dwi Ajeng Adhe Safitri Arina Setyaningtyas Aris Wiji Utami Aryati Aryati Aryati Aryati Atika Atika Atika Atika Atika Bangkit Putrawan Bastiana Bermawi Basuki, Setio Budi Prasetyo Budi Utomo Budi Utomo Budiono Budiono Bulqis Inas Sakinah Bulqis Inas Sakinah Candra Maulana Catarina Rani Cissy B Kartasasmita Cissy B. Kartasasmita Cita Rosita Sigit Prakoeswa Darto Saharso Dessy Putri Pratiwi Destasari Tri Hartanti Desy Primayani Djoko Marsudi Dwi Prasetyo Dwi Prasetyo Dwiyanti Puspitasari, Dwiyanti Edward Adijaya Rusli Egi Arguni Endyka Erye Frety Erna Supatmini Erni Rosita Dewi Esti Yunitasari Estin Puspaningrum Eveline Irawan Eveline Irawan Fadilla, Aulia Nur Febtarini Rahmawati Ferdinandus, Euvanggelia Dwilda Fitri Ramadhani Fitriah Fitriah Fitriah, Muhammad Yasin Flora Ramona Sigit Prakoeswa Gatot Irawan Sarosa Gatot Irawan Sarosa, Gatot Irawan Gunadi Ranu, I Gusti Made Reza Hanifah Oswari Hanifah Oswari Hanna Dyahferi Anomsari Haq, Arini Hardyanto Soebono Hari Basuki Notobroto Hartono Gunardi Hartono Gunardi Hasan, Nur Aini Hendrata, Adi Pramono Hilwana, Lutifta I Dewa Gede Ugrasena I Gusti Ngurah Twi Adnyana Ida Safitri Laksanawati Ilya Krisnana, Ilya Irawan, Eveline Irene Ratridewi Irwanto Irwanto, Irwanto Ismoedijanto Isnin Anang Marhana Jihan Kalishah Johanis Johanis Juniastuti Juniastuti Juniastuti Juniastuti Jusak Nugraha Kartina, Leny Kevin Sastra Dhinata Khen Mikhael Kristina Marbun Kristoforus Samson Kusnandi Rusmil Kusnandi Rusmil Laili Primasari Laksmi Wulandari Lilik Djuari Linda Dewanti M. Y. Probohoesodo M. Yulianto Listiawan M.Y. Probohoesodo Maddepunggeng, Martira Martira Maddepunggeng Ma`ruf, Anwar Mei Neni Sitaremi Mei Neni Sitaresmi Mufidah Binti Eka Muhammad Akbar Panjinegara Muhammad Miftahussurur Muhammad Vitanata Arfijanto, Muhammad Vitanata Muntia Rizki Alzahra Mustikasari, Rahma Ira MUTHMAINNAH Muthmainnah Muthmainnah Muziburrahman Muziburrahman Nastiti Kaswandani Natalia Yuwono Nihar, Mahdiyyah Husna Nike Aprilidia Nugraheny, Risca Ayu Parwati S. Basuki Parwati Setiono Basuki Pasulu, Soraya Salle Polanunu, Masayu Ramadhani Praswitasari, Rengganis Prodjosoewojo, Susantina Pudji Lestari Raihan Raihan Raihan Raihan, Raihan Rania, Najwa Miftah Ratni Indrawanti Reka Elvia Dirda Prasasta Renaldy, Raden Bagus Yanuar Retno Asih Setyoningrum Retno Palupi Retnosari Widowati Risa Etika, Risa Rossyanti, Lynda Rusli, Musofa Sabrina, Haifa Rafiqa Salma Asri, Hanifa Irfani Salma, Zukhaila Samson, Kristoforus Santi Martini Sari, Arabella Vonia Sari, Marlita Mustika Sarjana, IWayan Savitri Laksmi Winaputri Sesilia Serly Kebo Setiawati, Yunias Setyo Handryastuti Soedjatmiko Soedjatmiko Soedjatmiko Soegianto, Sugi Deny Pranoto Sofia Alfarizi Sopha, May Ira Sri Rejeki H Hadinegoro. Sri Rezeki S. Hadinegoro, Sri Rezeki S. Sri Umijati Sri Utami Sriwijayanti Sulistyawati Sugi Deny Pranoto Soegianto Suhintam Pusarawati Sukmawati Basuki Sulistiawati Sulistiawati Sulistiawati Sulistiawati Sulistiawati Sumaryono Sumaryono Sunari, I Gusti Agung Ayu Eka Putri Supiatun.M, Lilis Sri Susanti Susanti Susanto Nugroho Sutjonong, Tioky Theresia Indah Budhy Sulisetyawati Thiono, Marischa Tita Wafirotul Rizqi Hasanah Widodo Darmowandowo Woro Setia Ningtyas Yuli Astika Yulia Nadar Indrasari Yulida Mufidah Zakiudin Munasir Zakiudin Munasir