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All Journal Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Jurnal Kedokteran JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Panrita Abdi - Jurnal Pengabdian pada Masyarakat Acta Pharmaciae Indonesia : Acta Pharm Indo Jurnal Biologi Tropis Jurnal Penelitian Farmasi Indonesia SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pengabdian Magister Pendidikan IPA GERVASI: Jurnal Pengabdian kepada Masyarakat Jurnal Abdi Insani Community Development Journal: Jurnal Pengabdian Masyarakat Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Kesehatan Tambusai Sasambo Journal of Pharmacy INDRA: Jurnal Pengabdian kepada Masyarakat CERATA Jurnal Kefarmasian Indonesia
Nisa Isneni Hanifa
Program Studi Farmasi, Fakultas Kedokteran, Universitas Mataram, Mataram, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Solvent optimization of flavonoid extraction from Moringa oleifera L. using simplex lattice design Oktaviana, Siti Muhsonah; Hajrin, Wahida; Hanifa, Nisa Isneni
Acta Pharmaciae Indonesia Vol 10 No 1 (2022): Acta Pharmaciae Indonesia : Acta Pharm Indo
Publisher : Pharmacy Department, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.api.2022.10.1.5271

Abstract

Background: Flavonoids found mainly as pharmacologically active natural ingredient of moringa (Moringa oleifera L.). Therefore, optimizing the solvent to maximize the levels of flavonoid components is needed. Objective: This study was conducted to determine the optimum solvent composition for extracting flavonoid compounds from moringa leaves using the simplex lattice design (SLD). Methods: Moringa leaves were extracted using the sonication method with five combinations of 96% ethanol and water as the solvent. The solvent composition was optimized using Design-Expert version 11 software. Moreover, UV-Vis spectrophotometry was used to screen and identify flavonoid content. Results: Flavonoids were detected in moringa extract. Using the F test, a valid SLD equation, y= 440,243(A) + 142,983(B) - 47,324(A)(B), was obtained. This equation shows that the solvent ethanol 96% : water (100:0) was the best solvent and produced the maximum amount of moringa flavonoid content, which was 440,2427 mg QE/g extract. Conclusion: The flavonoid content was directly proportional to the high composition of 96% ethanol.
Optimasi formula sampo ekstrak etanol daun delima (Punica granatum L.) dengan metode Simplex Lattice Design Jannah, Syifaul; Hajrin, Wahida; Hanifa, Nisa Isneni
Sasambo Journal of Pharmacy Vol. 5 No. 2 (2024): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v5i2.347

Abstract

Anti-dandruff shampoo on the market still uses zinc pyriton which has the side effect of causing hair loss. Pomegranate leaves have strong antifungal activity against dandruff-causing fungi. This research aims to determine the optimum formula and physical properties of pomegranate leaf shampoo preparations with variations of SLS and cocamide DEA. The ethanol extract of pomegranate leaves was extracted by soxhletation and carried out in a tube test. Eight shampoo formula designs were determined using the SLD method. The shampoo was tested for foam height, pH, and viscosity to obtain the optimum formula. The optimum shampoo preparation was tested for physical properties, including organoleptic tests, homogeneity, foam stability, foam height, pH, and viscosity. The results of the test for the physical properties of the optimum shampoo preparation were verified using the SPSS application with the one-sample t-test method. Pomegranate leaf ethanol extract positively contains alkaloids, flavonoids, tannins, and saponins. The optimization results obtained the optimum shampoo formula, namely a combination of SLS 5.5% and cocamide DEA 15.5%. Optimum formula shampoo has a black color, menthol odor, gel form, ingredients mixed homogeneously, foam stability 81.83%, foam height 9.30 ± 0.26 cm, pH 5.91 ± 0.45, and viscosity 1646.66 ± 220.23 cP.
MERIAH: MENULIS ARTIKEL ITU MUDAH DENGAN METODE CIRC (COOPERATIVE INTEGRATED READING AND COMPOSITION) Candra Eka Puspitasari; Ni Made Amelia Ratnata Dewi; Nisa Isneni Hanifa; Astri Ferdiana; Dinatul Aini; Sulthon Annaji
GERVASI: Jurnal Pengabdian kepada Masyarakat Vol. 8 No. 2 (2024): GERVASI: Jurnal Pengabdian Kepada Masyarakat
Publisher : LPPM IKIP PGRI Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31571/gervasi.v8i2.7340

Abstract

Publikasi ilmiah merupakan salah satu syarat yudisium bagi sarjana di Universitas Mataram, namun jumlah publikasi ilmiah yang dilakukan mahasiswa masih kurang. Kurangnya minat mahasiswa dalam melakukan publikasi dapat disebabkan oleh pemahaman yang masih minim terkait penulisan artikel. Tujuan kegiatan ini untuk meningkatkan kompetensi mahasiswa Farmasi NTB dalam melakukan publikasi ilmiah. Kegiatan ini dilakukan dengan metode CIRC (Cooperative Integrated Reading and Composition). Kegiatan ini terdiri dua kegiatan yaitu seminar dan workshop. Jumlah peserta seminar 34 mahasiswa dan 15 mahasiswa yang mengikuti workshop. Tingkat pemahaman mahasiswa dilihat dengan melakukan pre-test dan post-test. Rata-rata nilai pre-test dan post-test seminar adalah 46,27% dan 62,61% dan pada workshop adalah 58,33% dan 55%. Terdapat kenaikan nilai pengetahuan mahasiswa pada sesi seminar, namun pada sesi workshop terdapat penurunan, hal ini dapat disebabkan oleh kejenuhan mahasiswa ketika sesi workshop. Berdasarkan hasil pengabdian ini, dapat disimpulkan terdapat peningkatan pengetahuan mahasiswa terhadap penulisan artikel ilmiah.
Optimasi Formula Krim Ekstrak Daun Katuk (Sauropus Androgynus) Variasi Konsentrasi Asam Stearat, Trietanolamin, dan Gliserin Lestari, Febia Arien; Hajrin, Wahida; Hanifa, Nisa Isneni
Jurnal Kefarmasian Indonesia VOLUME 10, NOMOR 2, AGUSTUS 2020
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v10i2.2496

Abstract

Sauropus androgynus (L.) Merr.) contain secondary metabolite compounds: flavonoids and polyphenols which has bioactivity as antioxidants. Antioxidants act as photoprotector, so it can be formulated into sun protection product. The selection of cream base is very important due to it’s not only as vehicle of active ingredients but also affecting cream’s physical properties and effectiveness. This study aims to determine the composition of the optimum base formula and evaluation formula cream of extract katuk leaves with variations concentration of stearic acid, TEA, and glycerin. Formula optimization was conducted through the Simplex Lattice Design methode with 13 formulas. The results of evaluation were processed with Design Expert software. The optimum formula was respectively at 13.16% stearic acid, 12% glycerin, and 3.84% TEA. The optimum formula cream evaluation was spreadability in 4.89 cm, 0.56 s stickiness power, and pH 6,1. Acceptability test results showed that the cream could accepted by society very well.
Pelatihan Pembuatan Sabun Dari Minyak Jelantah Pada Kader PKK Di Desa Bengkaung Hanifa, Nisa Isneni; Hidayati, Agriana Rosmalina; Mukhlishah, Neneng Rachmalia Izzatul; Subaidah, Windah Anugrah; Purnomo, Indra; Bayani, Faizul
Jurnal Pengabdian Magister Pendidikan IPA Vol 7 No 4 (2024): Oktober-Desember 2024
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpmpi.v7i4.9588

Abstract

The repeated use of cooking oil more than twice is still common in Indonesian society. However, used cooking oil can negatively affect health, being even more detrimental than saturated fatty acids. Additionally, it contributes to pollution in soil and water. One effective method for repurposing used cooking oil is by converting it into soap. This community service initiative aims to promote the utilization of used cooking oil in economically valuable products while reducing the amount of waste oil that is discarded into the environment. The training was conducted for PKK cadres in Bengkaung Village and facilitated by pharmacists, dermatologists, and students from the Faculty of Medicine and Health Sciences at the University of Mataram. The soap-making process begins by adding charcoal to the used cooking oil for 72 hours. This step helps remove hazardous substances and unpleasant odors. Afterward, the oil is filtered and combined with essential soap-making ingredients, including sunflower oil, virgin coconut oil (VCO), olive oil, sodium hydroxide (NaOH), and water. NaOH is critical for the saponification process, which transforms the oil into soap. To enhance the aesthetic value and benefits of the soap, ingredients like honey, yogurt, or natural dyes such as butterfly pea flowers can be incorporated. The mixture is then poured into molds and allowed to harden. Given the simple process and the ease of obtaining the necessary tools and materials, the PKK cadres in Bengkaung Village have shown enthusiasm for making soap from used cooking oil. This activity is expected to broaden their knowledge and provide business opportunities to help increase family income in the village.
STUDI ETNOMEDISIN RAMUAN OBAT DI DESA OBEL-OBEL KECAMATAN SAMBELIA KABUPATEN LOMBOK TIMUR Setiawan, Wahyu Aldi; Hanifa, Nisa Isneni; Sukenti, Kurniasih
Jurnal Kesehatan Tambusai Vol. 6 No. 1 (2025): MARET 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v6i1.39519

Abstract

Etnomedisin merupakan cabang dari ilmu medis yang membahas asal mula penyakit, serta sebab-sebab dan cara pengobatan menurut kelompok masyarakat tertentu. Masyarakat di Desa Obel-Obel Kecamatan Sambelia masih menggunakan pengobatan alternatif yang dilakukan oleh belian menggunakan tumbuhan sebagai obat. Penelitian ini bertujuan untuk mengetahui karakteristik informan serta komposisi, cara pembuatan dan cara penggunaan ramuan, dan nilai penting tumbuhan. Penelitian ini dilakukan secara kualitatif dan kuantitatif, data kuantitatif berupa nilai penting yang di dapatkan akan diolah menggunakan parameter Index of Cultural Significant (ICS) dan Fidelity Level (FL). Berdasarkan hasil wawancara dengan 6 orang informan, terdapat 24 spesies dari 18 famili tumbuhan yang digunakan untuk pembuatan ramuan penyakit demam, batuk, pencernaan, kulit, dan patah tulang. Proses pembuatan ramuan yaitu digiling dan diseduh. Terdapat cara penggunaan ramuan yaitu diminum, dioles, ditempel, dan dimakan. Nilai ICS tertinggi, yaitu 90 pada tumbuhan sirih (Piper betle L). Nilai FL tertinggi kategori demam yaitu Pohon kuda (Lannea coromandelica L) dengan nilai 50%. Nilai FL tertinggi kategori batuk yaitu sirih (Piper betle L) dengan nilai 49,8%. Nilai FL tertinggi kategori pencernaan yaitu jambu biji (Psidium guajava L) dengan nilai 50%. Nilai FL tertinggi kategori kulit yaitu sirih (Piper betle L) dengan nilai 66,4 % dan kunyit (Curcuma longa L) dengan nilai 66,4%. Nilai FL tertinggi kategori patah tulang yaitu sirih (Piper betle L) dengan nilai 33,2%. Dari data nilai pemanfaatan tertinggi perlu dilakukan penelitian lebih lanjut untuk penyakit demam, batuk, pencernaan, kulit, dan patah tulang yaitu, Lannea coromandelica L, Piper betle L, dan Psidium guajava L.
UJI AKTIVITAS MINYAK SONGAK TERHADAP PROSES PENYEMBUHAN LUKA INSISI PADA TIKUS (RATTUS NORVEGICUS) khalil, Luthfi Riza; Rosmalina, Agriana; Hanifa, Nisa Isneni
Jurnal Kesehatan Tambusai Vol. 6 No. 2 (2025): JUNI 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v6i2.45492

Abstract

Minyak Songak merupakan obat tradisional yang berasal dari Desa Songak, Kecamatan Sakra, Kabupaten Lombok Timur yang secara empiris Minyak Songak dipercaya dapat menyembuhkan luka dengan cepat. Namun, belum ada penelitian secara ilmiah terkait aktivitas Minyak Songak dalam penyembuhan luka. Penelitian ini bertujuan untuk mengetahui aktivitas dan cara penggunaan terbaik dari Minyak Songak dalam proses penyembuhan luka. Metode uji luka insisi dilakukan secara in vivo menggunakan hewan uji tikus (Rattus norvegicus) yang dibagi kedalam empat kelompok secara acak dan diuji selama 20 hari. Kelompok I adalah kontrol positif yang diberikan povidone iodine secara topikal sehari dua kali, kelompok II adalah kontrol negatif yang tidak diberikan perlakuan, kelompok III adalah kelompok uji yang diberikan Minyak Songak secara oral dan topikal sehari satu kali, kelompok IV adalah kelompok uji yang diberikan Minyak Songak secara topikal sehari dua kali. Hasil yang didapatkan berupa persentase penyembuhan luka, diperoleh bahwa kelompok IV menunjukkan hasil terbaik pada hari ke-8 sebesar 98% dibandingkan dengan kelompok kontrol. Hasil uji tensile strength menunjukkan bahwa kelompok IV memiliki kekuatan penutupan luka terbaik sebesar 11,316 g/mm2 dibandingkan dengan kelompok kontrol. Berdasarkan hasil penelitian tersebut dapat disimpulkan bahwa Minyak Songak dengan cara penggunaan topikal sehari dua kali memiliki aktivitas penyembuhan luka dan dapat menyembuhkan luka dengan cepat.
Potential of Ipomoea pes-caprae Extract as an Antibacterial: A Literature Review Nuralyza, Imasayu; Hanifa, Nisa Isneni
Jurnal Biologi Tropis Vol. 25 No. 2 (2025): April-Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i2.8839

Abstract

The increasing prevalence of antibiotic resistance shows the urgent need for discovering alternative compounds with potential antibacterial activity. Ipomoea pes-caprae (commonly known as katang-katang) has emerged as a promising natural source of antibacterial agents due to its bioactive constituents, including phenolics, alkaloids, flavonoids, and saponins. The purpose of this article is to review and compare previously reported antibacterial research findings of Ipomoea pes-caprae against various bacterial species. The literature review was conducted using relevant sources obtained from Google Scholar and PubMed databases, covering publications from 2014 to 2024. The findings show that different parts of Ipomoea pes-caprae exhibit antibacterial activity against both Gram-positive and Gram-negative bacterial strains, attributed to the presence of antibacterial compounds. Factors influencing the antibacterial activity of the extracts include the type of test bacteria, the extract concentration, and the solvent used. It can be concluded that Ipomoea pes-caprae has potential as an antibacterial agent.
KARAKTERISTIK PENGETAHUAN, SIKAP DAN PERILAKU MAHASISWA PENDERITA AKNE VULGARIS DI UNIVERSITAS MATARAM TERHADAP PENYAKIT DAN PENGOBATAN Prianggawe, Prianggawe; Andanalusia, Mahacita; Hidajat, Dedianto; Hidayati, Agriana Rosmalina; Hanifa, Nisa Isneni; Hajrin, Wahida
Jurnal Kesehatan Tambusai Vol. 6 No. 3 (2025): SEPTEMBER 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v6i3.49895

Abstract

Penelitian ini mengkaji pengetahuan, sikap, dan perilaku mahasiswa di Universitas Mataram terhadapAV yaitu suatu kondisi kulit inflamasi kronis yang umum disebabkan oleh Cutibacterium acnes danStaphylococcus epidermidis. Kondisi ini banyak ditemukan pada remaja akhir dan dewasa muda berusia 18-25tahun yang sebagian besar adalah mahasiswa. Tujuan penelitian ini yaitu mengetahui karakteristik pengetahuan,sikap dan perilaku mahasiswa penderita AV terhadap penyakit dan pengobatan. Metode penelitian inimenggunakan desain deskriptif dengan pendekatan cross-sectional yang melibatkan 81 responden yang dipilihdengan metode purposive sampling. Teknik pengambilan data dikumpulkan menggunakan kuesioner dandianalisis secara deskriptif. Data disajikan dalam bentuk tabel untuk memvisualisasikan persebaran jawaban.Hasil penelitian menunjukan sebagian besar responden memiliki pengetahuan baik (81,4%), sikap yang positif(100%) dan perilaku (96%). Instrumen penelitian ini telah menunjukkan validitas dan reliabilitas yang dapatdiuji ulang pada scope penelitian yang lebih besar dengan populasi yang lebih beragam meliputi masyarakatumum, mahasiswa, dan kelompok usia berbeda.Kata kunci: Akne vulgaris, Mahasiswa, Pengetahuan, Perilaku, Sikap
Preliminary In Vitro Antiplatelet Potential of Ipomoea pes-caprae from North Lombok with Adenosine Diphosphate-Induced Platelet Aggregation Ilsa Hunaifi; Dewi Suryani; Lalu Husnul Hidayat; Muhammad Naufal Farras Ananta; Muhammad Iqbal Farobbi; Nisa Isneni Hanifa; Raisya Hasina
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 12 No. 2 (2025): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v12i22025.229-246

Abstract

Background: Cardiovascular diseases, particularly ischemic stroke, remain a global health burden, necessitating potential candidate for further antiplatelet with fewer side effects. Objectives: This study aimed to evaluate the antiplatelet potential of ethanolic extracts from the leaves and stems of Ipomoea pes-caprae (Katang-katang) from North Lombok, Indonesia, through ADP-induced platelet aggregation. Phytochemical screening, total tannin quantification, and in vitro antiplatelet assays were conducted. Methods: The leaves and stems were macerated with 96% ethanol, followed by qualitative phytochemical tests, Folin-Ciocalteu-based tannin analysis, and platelet aggregation inhibition assays using human platelet-rich plasma. Results: The extracts contained alkaloids, flavonoids, and tannins, with higher tannin levels in leaves (4.02 ± 0.02 mgEAT/g) than stems (3.67 ± 0.17 mgEAT/g). Concentration-dependent antiplatelet activity was observed, with leaf extracts showing inhibition (85.9% at 2000 μg/mL) compared to stems (79.5%) and aspirin (77.3%). IC₅₀ values were 727.78 μg/mL (leaves) and 349.95 μg/mL (stems). Statistical analysis confirmed significant differences across concentrations (p < 0.05). Conclusion: These findings demonstrate that Ipomoea pes-caprae exhibits potent antiplatelet activity, attributed to its tannin and phytochemical content, with leaves being more effective. Although these findings suggest preliminary antiplatelet potential, further analysis is required to validate the method using aspirin IC₅₀, and subsequent in vivo and pharmacological investigations are necessary before therapeutic application can be claimed.
Co-Authors Abdillah, Lalu Khairi Ahmad, Dzakiyyah Sulthanah Aini, Siti Rahmatul Alamanda, Baiq Irzana Putri Aliefman Hakim Amni Hamid Ananta, Muhammad Naufal Farras Angelina, Varelia Anggit Listyacahyani Sunarwidhi Annisa Nurrahman Arinda Eka Muliani Astri Ferdiana Azizah, Hidayatul Bayani, Faizul Candra Eka Puspitasari Dani Syaiful Akbar Dedianto Hidajat Dewi Suryani Dewi Suryani Dinatul Aini Dyke Gita Wirasisya Dyke Gita Wirasisya Dyke Gita Wirasisya Dyke Gita Wirasisya Farobbi, Muhammad Iqbal Febia Arien Lestari Febriyanto Febriyanto Fidrus Affandy Fitri Haryani Fitri Haryani Fradnya Vrianka Praharsini Hajrin, Wahida Halimatussakdiyah Halimatussakdiyah, Halimatussakdiyah Handa Muliasari Happy Elda Murdiana, Happy Elda Hasin, Raisya Hidayati, Agriana Rosmalina Hidayati, Regina Tria Hidayatul Ihsan I Komang Ary Werdhi Widnyana Ilsa Hunaifi Ilsa Hunaifi, Ilsa Iman Surya Pratama Indra Purnomo Istiqamah, Juhratul Istri Bartini Jannah, Syifaul Kania, Nadira Kartika Permatasari Khalil, Luthfi Riza Kurniasih Sukenti Kurniasih Sukenti Laksono Trisnantoro Lalu Husnul Hidayat Lestari, Febia Arien Luthfanto Hafizhuddin Mahacita Andanalusia Mahacita Andanalusia Monika Sofi Nandini Muhamad Haikhal Muhammad Iqbal Farobbi Muhammad Naufal Farras Ananta Mukhlishah, Neneng Rachmalia Izzatul Muliasari, Handa Muliasari, Handa Neneng Rachmalia Izzatul Mukhlishah Ni Made Amelia Ratnata Dewi Nikasius Jonet Sinangjoyo Nmar Dewi Novi Susianti Novisma, Mutia Nuralyza, Imasayu Nurul Istiqomah Ocktaviana Saputri, Legis Oktaviana, Siti Muhsonah Permatasari, Lina Permatasari, Ni Made Ayu Dinda Praditama, Lalu Denendra Pramudia, Cindy Prianggawe, Prianggawe Raisya Hasina Raisya Hasina Ramadhan, Muhammad Arif Ramadhan, Muhammad Rafi Bintang Ridwan, Sucilawaty Rizka Dwi Rahmitasari rizki, alpa alfi Rizkika, Adila Rosmalina, Agriana Septia Budi Utami Setiawan, Wahyu Aldi Siti Muhsonah Oktaviana Sugeng Santoso Sulthon Annaji Sunarwidhi, Anggit Listyacahyani Surya Febrianto SUSANTI Susanti Susanti Wahida Hajrin Wahida Hajrin Wahida Hajrin Wahida Hajrin Wahida Hajrin Wahyu Widyaningsih Wardani, Ray Haerul Windah Anugrah Subaidah Yayuk Andayani Yohanes Juliantoni Yosua Adi Kristariyanto Zulfiana Fitrianingrum Annas