Article Per Year (5 Year)
p-Index From 2020 - 2025
3.687
P-Index
This Author published in this journals
All Journal Majalah Kedokteran Bandung Medula Juke Jurnal Kesehatan JURNAL ILMIAH KESEHATAN SANDI HUSADA Bioscientia Medicina : Journal of Biomedicine and Translational Research JURNAL PENELITIAN PERAWAT PROFESIONAL JK Unila (Jurnal Kedokteran Universitas Lampung) Bioscientia Medicina : Journal of Biomedicine and Translational Research Indonesian Journal of Nursing and Health Sciences (IJNHS) Majority Jurnal Ilmiah Kesehatan Sandi Husada JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia
Rizki Hanriko
Universitas Lampung
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

Published : 33 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 33 Documents
Search

 1   2   3   4 
PENGARUH EKSTRAK BAWANG PUTIH (Alium sativum) TERHADAP GAMBARAN HISTOPATOLOGI HEPAR PADA TIKUS PUTIH (Rattus norvegicus) GALUR Sprague- dawley YANG DIINDUKSI STREPTOZOTOCIN Fadly, Ahmad Aulia; Windarti, Indri; Hanriko, Rizki
Medula Vol 14 No 6 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i6.1154

Abstract

Diabetes Mellitus (DM) is a chronic disease characterized by blood sugar levels that exceed normal limits. Chronic DM can cause liver complications in the form of inflammation. Streptozotocin can induce mice to become a DM model and can also directly damage the liver. Garlic (Allium sativum) is a tuber that is often found in Indonesia. The various compounds contained in it have anti-diabetic and antioxidant effects which have the potential to prevent inflammation in the liver. This research was conducted to determine the effect of garlic extract (Allium sativum) on histopathological features in the form of lymphocyte cell infiltration in the portal and lobular tracts of the liver in white rats (Rattus norvegicus) of the Sprague-dawley strain induced by streptozotocin. The method used was a randomized controlled design with a pre-clinical Post-test Only Control Group Design pattern. This study used 24 mice divided into 4 groups with 6 mice in each group. The appearance of lymphocyte cell infiltration will be assessed based on the Omenetti scoring. The mean scores for lymphocyte cell infiltration in the portal tract obtained were KN=0.22, K+=2.10, P1=0.60, and P2=0.56. From the analysis using the One-Way ANOVA test followed by the Post Hoc Benferroni test, the results showed a significant difference in scores between K+ and P1 and P2. Meanwhile, the mean scores for lymphocyte cell infiltration in the lobular area obtained were KN=0.50, K+=1.16, P1=0.50, and P2=0.33. From the analysis using the Kruskal-Wallis test, no significant differences in scores were found between all groups. There was an effect of garlic extract (Allium sativum) on the infiltration of lymphocyte cells in the portal tract and no effect was found on the lobular area of ​​the liver in white rats (Rattus norvegicus) of the Sprague-dawley strain which were induced by streptozotocin.
Mesothelin Sebagai Biomarker Deteksi Dini Kanker Pankreas Fauziyyah Nuur Al azizah; Rizki Hanriko
Jurnal Ilmiah Kesehatan Sandi Husada Vol 8 No 2 (2019): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v10i2.132

Abstract

Abstract: Pancreatic cancer is difficult to diagnose at an early stage and generally has a poor prognosis. Surgical resection is the only potentially curing treatment for pancreatic carcinoma. To improve the prognosis of this disease, it is important to detect tumors at an early stage. The lack of sensitive and specific tumor markers for early diagnosis has a major contribution to the poor prognosis. For this reason, it is necessary to make an early diagnosis of pancreatic cancer through a biomarker in the form of mesothelin which can be found in the blood and urine. Mesothelin is a glycoprotein that is expressed in normal mesothelial cells but is overexpressed in pancreatic cancer. How to check mesothelin levels in the blood can use ELISA and for those in the urine can use spectrophotometry. And mesothelin has been shown to increase in early stage cancer and 64% in metastatic cancer. Mesothelin can also be expressed in other organs such as endometrioid adenocarcinoma (59-64%), cervix (25%), pancreas (86-100%), colorectal (28-50%), esophagus (25-46%) and gastric carcinoma (27-58%) but in pancreatic cancer the amount of mesothelin produced is greater. Therefore mesothelin can be an early detection biomarker that is useful for pancreatic cancer Keywords: biomarkers, mesothelin, blood, urine, overexpression
HUBUNGAN USIA DAN HIPERTENSI DENGAN KEJADIAN BPH DI BANGSAL BEDAH RSUD DR. H. ABDUL MOELOEK TAHUN 2017 Muhammad Iz Zuddin Adha; Rizki Hanriko; Dian Isti Angraini
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol 8 No 1 (2020): JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Volume 8.1 Edisi November 201
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53366/jimki.v8i1.34

Abstract

ABSTRAK Pendahuluan: Benign prostate hyperplasia (BPH) sering terjadi pada usia lanjut. Sekitar 50% laki-laki yang memiliki usia diatas 50 tahun diketahui memiliki bukti patologi BPH. Usia dan hipertensi diketahui menjadi faktor dalam proses terjadinya BPH. Tujuan dari penelitian ini adalah untuk mengetahui hubungan usia dan hipertensi dengan kejadian BPH di Bangsal Bedah RSUD Dr. H. Abdul Moeloek tahun 2017. Metode: Penelitian ini menggunakan metode case control study. Jenis data yang dipakai adalah data sekunder dari rekam medis. Sampel diambil dari pasien bangsal bedah RSUD Dr. H. Abdul Moeloek tahun 2017. Teknik pengambilan sampel adalah consecutive. Analisis data dilakukan dengan analisis univariat, analisis bivariat dengan chi-square, dan analisis multivariat dengan metode regresi logistik ganda. Hasil: Rerata usia subjek penelitian adalah 66,00 ± 10,17 tahun untuk kelompok kasus. dan 53,36 ± 16,19 tahun untuk kelompok kontrol. Pada kelompok kasus, persentase hipertensi sebesar 36,7% sedangkan yang tidak hipertensi sebesar 63,3%. Pada kelompok kontrol persentase hipertensi sebesar 10% sedangkan yang tidak hipertensi sebesar 90%. Hasil penelitian menunjukan bahwa usia ?50 tahun (OR = 11,947; nilai p=0,009) dan hipertensi (OR = 7,898; nilai p=0,017) merupakan faktor risiko terjadinya BPH. Pembahasan: Pada usia tua, terjadi ketidakseimbangan hormon testosteron dan estrogen sehingga mempengaruhi pembesaran kelenjar prostat. Peningkatan ekspresi VEGF (Vascular Endothelial Growth Factor) pada kondisi hipertensi akan menginduksi angiogenesis dan mengakibatkan terjadinya peningkatan gejala klinis BPH. Kesimpulan: Terdapat hubungan usia dan hipertensi dengan kejadian BPH di Bangsal Bedah RSUD Dr. H. Abdul Moeloek tahun 2017. Kata Kunci: BPH, hipertensi, usia ABSTRACT Background: Benign prostate hyperplasia (BPH) often occurs in old age. About 50% of men over 50 years are known to have BPH pathology evidence. Age and hypertension are known to be factors in the process of BPH. The purpose of this study was to determine the relationship of age and hypertension with the occurrence of BPH in the Surgical Ward of RSUD Dr. H. Abdul Moeloek in 2017. Methods: This study uses a case control study method. The type of data used is secondary data from medical records. Samples were taken from surgical ward patients of Dr. H. Abdul Moeloek in 2017. The sampling technique was consecutive sampling. Data analysis was performed with univariate analysis, bivariate analysis with chi-square, and multivariate analysis with multiple logistic regression methods. Results: The mean age of the study subjects was 66.00 ± 10.17 years for the case group. and 53.36 ± 16.19 years for the control group. In the case group the percentage of hypertension was 36.7% while non-hypertension was 63.3%. In the control group the percentage of hypertension was 10% while non-hypertension was 90%. The results showed that age ?50 years (OR = 11,947; p value = 0.009) and hypertension (OR = 7.898; p value = 0.017) were risk factors for BPH. Discussion: In old age, there is an imbalance of the hormones testosterone and estrogen which affects the enlargement of the prostate gland. Increased VEGF (Vascular Endothelial Growth Factor) expression in hypertensive conditions will induce angiogenesis and result in an increase in clinical symptoms of BPH. Conclusion: There is a relationship between age and hypertension with the occurrence of BPH in the Surgical Ward Dr. H. Abdul Moeloek in 2017. Keywords : BPH, hypertension, age
Co-Authors - Muhartono - Muhartono Ahmad Syah Putra Alif Fernanda Putra Anggun Elidiya Annisa Shafira Pramono ari wahyuni Ari Wahyuni Dian Isti Angraini Dian Isti Angraini Dwi Indria Anggraini Eca Cania Ety Apriliana Ety Apriliana Fadly, Ahmad Aulia Fatahillah, Fatahillah Fauziani, Andra Nabila Fauziyyah Nuur Al azizah Gede Ardi Saputra Hanna Mutiara Haryani Dwita Haula Rizqiyah Helsa Apty Tamara Hendra Tarigan Sibero Hendri Busman Indri Windarti KHAIRUNNISA SALSABILA M. Yusran Mohamad Reihansyah Deswindra Muhammad Iz Zuddin Adha Muhartono Muhartono Muhartono Muhartono Muhartono Muhartono Nabil Abdurrahman Naufal Rasyid Aswan Nisa Karima Okki Muhammad Fajar Muthahhari Oktadoni Saputra Pairulsyah Pairulsyah Putu Devie Sri Astari Rani Himayani Ratna Dewi PS Ratna Dewi Puspita Sari Retno Ariza Soeprihatini Rodiani Septiani, Linda Siti Raqiya Rasyid Suharmanto Suharmanto Suharyani Susianti Susianti Tasya Khalis Ilmiani Tri Umiana Soleha Trixie Almira Veny Anisya Waluyo Rudiyanto Yovani Rehuel Br Sitepu